助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   chronic b lymphocytic leukemia 的翻译结果: 查询用时:0.007秒
图标索引 在分类学科中查询
所有学科
心血管系统疾病
肿瘤学
更多类别查询

图标索引 历史查询
 

chronic b lymphocytic leukemia
相关语句
  慢性b淋巴细胞白血病
     Cloning of Ig Fab genes of patients with chronic B lymphocytic leukemia and sequences analysis of their variable regions
     慢性B淋巴细胞白血病患者免疫球蛋白Fab段基因克隆及其可变区序列分析
短句来源
     Here we investigated acute and chronic B lymphocytic leukemia (B-ALL and B-CLL) in terms of expression and functions of chemokines and their receptors, and explored the pathogenesis of B lymphocytic leukemia.
     我们初步研究了急性B淋巴细胞白血病(B-ALL)和慢性B淋巴细胞白血病(B-CLL)细胞表面趋化因子受体的表达情况,并结合相应的趋化因子,对B淋巴细胞白血病的发病机制进行了初步的探索。
短句来源
     ANALYSIS OF THE IMMUNOLOG1C PHENOTYPES IN CHRONIC B LYMPHOCYTIC LEUKEMIA
     慢性B淋巴细胞白血病的免疫表现型分析
短句来源
     Objective Sequences analysis of Ig variable regions from the peripheral blood mononuclear cells (PBMC) of patients with chronic B lymphocytic leukemia.
     目的 分析慢性B淋巴细胞白血病患者外周血单个核细胞免疫球蛋白Fab段基因。
短句来源
  “chronic b lymphocytic leukemia”译为未确定词的双语例句
     DETECTION OF TRISOMY 12 IN CHRONIC B LYMPHOCYTIC LEUKEMIA (B CLL) BY FLUORESCENCE IN SITU HYBRIDIZATION
     荧光原位杂交技术检测慢性B-CLL第12号染色体三体畸变
短句来源
     The results revealed that 4 cases were diagnosed as chronic B lymphocytic leukemia (B-CLL) , 1 case as B pro-lymphocytic leukemia (B-PLL) ,and these were subdivided into k and r types respectively, according to their different expressions of a single Ig light chain.
     根据表现型5例中有4例诊断为B—CLL,1例为幼淋巴细胞白血病(B—PLL),根据不同的轻链表达又分为κ型和λ型。
短句来源
     Nineteen kinds of McAbs were used to test the lymphocyte surface markers of the peripheral blood from 5 cases of chronic B lymphocytic leukemia, using indirect immunofluorescence technique,The stages of leukemic cell differentiation and immunologic typing were assessed according to their immunologic phenotypes.
     本研究应用19种单克隆抗体检测5例人类慢性B淋巴细胞性白血病(B—CLL)细胞的表现型,并据此进行免疫分型及细胞分化阶段的分析。
短句来源
  相似匹配句对
     Molecular Cytogenetics of Chronic Lymphocytic Leukemia
     慢性淋巴细胞白血病的分子细胞遗传学
短句来源
     Study of immunophenotype in chronic lymphocytic leukemia
     慢性淋巴细胞白血病的免疫表型研究
短句来源
     Progress in the drug therapy for chronic lymphocytic leukemia
     慢性淋巴细胞白血病的药物治疗进展
短句来源
     Molecular cytogenetic characteristics of chronic lymphocytic leukemia
     慢性淋巴细胞白血病的分子遗传学特点
短句来源
     ANALYSIS OF THE IMMUNOLOG1C PHENOTYPES IN CHRONIC B LYMPHOCYTIC LEUKEMIA
     慢性B淋巴细胞白血病的免疫表现型分析
短句来源
查询“chronic b lymphocytic leukemia”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  chronic b lymphocytic leukemia
Structural aspects of human IgM antibodies expressed in chronic B lymphocytic leukemia.
      
Lack ofdetectable somatic hypermutation in the V region of the Ig H chain gene of a human chronic B lymphocytic leukemia.
      


Nineteen kinds of McAbs were used to test the lymphocyte surface markers of the peripheral blood from 5 cases of chronic B lymphocytic leukemia, using indirect immunofluorescence technique,The stages of leukemic cell differentiation and immunologic typing were assessed according to their immunologic phenotypes. The results revealed that 4 cases were diagnosed as chronic B lymphocytic leukemia (B-CLL) , 1 case as B pro-lymphocytic leukemia (B-PLL) ,and these were subdivided...

Nineteen kinds of McAbs were used to test the lymphocyte surface markers of the peripheral blood from 5 cases of chronic B lymphocytic leukemia, using indirect immunofluorescence technique,The stages of leukemic cell differentiation and immunologic typing were assessed according to their immunologic phenotypes. The results revealed that 4 cases were diagnosed as chronic B lymphocytic leukemia (B-CLL) , 1 case as B pro-lymphocytic leukemia (B-PLL) ,and these were subdivided into k and r types respectively, according to their different expressions of a single Ig light chain.The malignant B cells in 3 cases of B-CLL are intermediately differentiated cells, the other one is differentiated as between the mature and intermediate stages in B cell development , and 1 case of PLI, revealed the characteristics of mature B cells.

本研究应用19种单克隆抗体检测5例人类慢性B淋巴细胞性白血病(B—CLL)细胞的表现型,并据此进行免疫分型及细胞分化阶段的分析。根据表现型5例中有4例诊断为B—CLL,1例为幼淋巴细胞白血病(B—PLL),根据不同的轻链表达又分为κ型和λ型。4例B—CLL中有3例细胞处于中间分化阶段,1例处于中间与成熟分化阶段之间。1例B—PLL则处于成熟分化阶段。

Using the polymerase chain reaction(PCR), the authors have amplified immunoglobulin heavy chain (IgH)gene from B-lymphocytic leukemic DNA samples. The IgH gene rearrangement in acute and chronic B-lymphocytic leukemia and lymphoid blast crisis of CML has been found unusual and specific. Some of them show two kinds of amplified products. Even if the leukemic cells are less than 4%, the unusual rearrangement of IgH can still be detected by the PCR method. The PCR technique is...

Using the polymerase chain reaction(PCR), the authors have amplified immunoglobulin heavy chain (IgH)gene from B-lymphocytic leukemic DNA samples. The IgH gene rearrangement in acute and chronic B-lymphocytic leukemia and lymphoid blast crisis of CML has been found unusual and specific. Some of them show two kinds of amplified products. Even if the leukemic cells are less than 4%, the unusual rearrangement of IgH can still be detected by the PCR method. The PCR technique is helpful for the diagnosis, therapy and prognosis of the B-lymphocytic leukemia.

用PCR方法对B-淋巴细胞白血病患者的免疫球蛋白(Ig)重链基因进行扩增。发现急、慢性B-淋巴细胞白血病、慢粒急淋变的Ig重链基因重排出现异常。有的患者出现两种基因扩增产物。即使在骨髓抑制期和完全缓解期白血病细胞少于4%时,也可以检出异常重排的Ig重链基因。本研究对B-淋巴细胞白血病的诊断和治疗具有重要意义。

Objective Sequences analysis of Ig variable regions from the peripheral blood mononuclear cells (PBMC) of patients with chronic B lymphocytic leukemia. Methods Total RNA was isolated from PBMC of patients with chronic B lymphocytic leukemia, oligo-dT-primed cDNA was synthesized from RNA. The cDNA was amplified by Taq DNA polymerase with a set of specific 5′ primers corresponding to Ig FR1 and 3′ primers corresponding to CH1(Cμ/C) or CL(Cκ/Cλ), the PCR products of variable regions of Ig heavy...

Objective Sequences analysis of Ig variable regions from the peripheral blood mononuclear cells (PBMC) of patients with chronic B lymphocytic leukemia. Methods Total RNA was isolated from PBMC of patients with chronic B lymphocytic leukemia, oligo-dT-primed cDNA was synthesized from RNA. The cDNA was amplified by Taq DNA polymerase with a set of specific 5′ primers corresponding to Ig FR1 and 3′ primers corresponding to CH1(Cμ/C) or CL(Cκ/Cλ), the PCR products of variable regions of Ig heavy (IgH) and light (IgL) chains were sequenced by ABI PRISM Dye terminator cycle sequencing ready reaction kit and ABI PRISM 310 Genetic Analyzer. The gene homology of variable regions of IgH and IgL chains was compared by using DNA tools 5 1 system and “the international immunogenetics database”. Results Four light chains and 3 heavy chains were amplified from 4 and 3 patients respectively. Homology analysis of the sequences of 4 light chains and 3 heavy chains were performed by DNA tools system. The sequences of light chains are high homologous. And the sequences of heavy chains are quite different. The homologous analysis of the sequences of variable region by using “the international immunogenetics database" showed that the sequences were higher homologous to idiotype gene of some B lymphocytic leukemia. Four VL genes belong to human Ig Vκ subgroup Ⅰ, 2 of 3 VH genes belong to VH3 family and 1 belongs to VH5 family. Conclusion Ig genes have idiotype and same disease may have same idiotype.

目的 分析慢性B淋巴细胞白血病患者外周血单个核细胞免疫球蛋白Fab段基因。方法 提取慢性B淋巴细胞白血病患者外周血单个核细胞RNA ,选用与IgFR15′和CH1Cμ 3′或CL区(Cκ/Cλ) 3′互补的多对引物 ,通过RT PCR扩增IgFab段基因 ,进行克隆和序列测定 ,并通过DNAtools和计算机网络对其可变区基因同源性进行分析和基因家族归类。结果  7例患者中 4例外周血单个核细胞扩增出轻链基因 ,3例扩增出重链基因。所扩增的 4条轻链基因均属于κ轻链 ,3条重链均为 μ链基因。利用DNAtools分析软件 ,对轻链和重链分别进行同源性比较 ,3条重链可变区基因差异较大 ,轻链可变区基因具有一定的同源性。对所扩增的Ig基因进行归类 ,结果 4例患者的轻链均属于VκI亚组 ;3例患者的重链中 2例属VH3家族 ,1例为VH5家族。结论 慢性B淋巴细胞白血病患者存在独特的决定簇和相似决定簇

 
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关chronic b lymphocytic leukemia的内容
在知识搜索中查有关chronic b lymphocytic leukemia的内容
在数字搜索中查有关chronic b lymphocytic leukemia的内容
在概念知识元中查有关chronic b lymphocytic leukemia的内容
在学术趋势中查有关chronic b lymphocytic leukemia的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社