助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   neuron calcium 的翻译结果: 查询用时:0.16秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

neuron calcium
相关语句
  神经元钙
     Conclusions In the early stage of brain injury, ACh can cause neuron calcium overload, oxide free radical reaction, cerebral vasospasm, and increase blood-brain barry(BBB) permeability. Scopolamine, a muscarinic receptor antagonist, can improve these pathologic changes. As a result, Sco has protective effects on brain tissue injury.
     结论 :脑外伤后早期ACh可致神经元钙超载、氧自由基反应、脑血管痉挛和血脑屏障 (BBB)通透性增强 ,M受体拮抗剂东莨菪硷可改善这些病理变化 ,具有脑保护作用
短句来源
  “neuron calcium”译为未确定词的双语例句
     Many factors can cause the neuron calcium homeostasis imbalance in Alzheimers disease. For example, the increase of intracellular calcium can induce the excitotoxicity, oxidative stress, Tau protein accumulation and hyperphosphylation, and vulnerable to the Aβ, activation of calpain and induce the apoptosis .
     AD的发病机制中多种因素可以使神经元 [Ca2 + ]i 平衡失调 ,而 [Ca2 + ]i 的升高可引起兴奋性毒性反应、自由基损伤、Tau蛋白的积聚和过度磷酸化、Aβ的毒性增大、激活Cal pain以及诱发细胞凋亡。
短句来源
  相似匹配句对
     Neuron Presynaptic Calcium Channel States and Its Equivalent Circuit
     神经元突触前膜C~(2+)通道状态特性及等效电路
短句来源
     About Calcium
     补钙切莫一“钙”而论
短句来源
     It implied that Puerarin could inhibit L-type calcium channel in neuron.
     提示临床上葛根素治疗缺血性中风可能与其抑制神经细胞L-型钙离子通道的开放防止钙超载有关。
短句来源
     Fenoprofen Calcium
     苯氧布洛芬钙
短句来源
     neuron and receptor.
     神经元普遍存在突触前受体;
短句来源
查询“neuron calcium”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  neuron calcium
These were the best-fit values for the squid neuron calcium channel.
      
This is also true of the two bag cell neuron calcium currents.
      
An understanding of their mechanism of modulation provides an added impetus for the molecular characterization of bag cell neuron calcium channels.
      


Alzheimers disease is correlated to the aging and the imbalance of the intracellular calcium homeostasis. Many factors can cause the neuron calcium homeostasis imbalance in Alzheimers disease. For example, the increase of intracellular calcium can induce the excitotoxicity, oxidative stress, Tau protein accumulation and hyperphosphylation, and vulnerable to the Aβ, activation of calpain and induce the apoptosis . The article reviews the advance about the calcium homeostasis imbalance...

Alzheimers disease is correlated to the aging and the imbalance of the intracellular calcium homeostasis. Many factors can cause the neuron calcium homeostasis imbalance in Alzheimers disease. For example, the increase of intracellular calcium can induce the excitotoxicity, oxidative stress, Tau protein accumulation and hyperphosphylation, and vulnerable to the Aβ, activation of calpain and induce the apoptosis . The article reviews the advance about the calcium homeostasis imbalance hypothesis in recent year.

阿尔采末病与衰老和细胞内钙稳态的失调等因素有关 ;AD的发病机制中多种因素可以使神经元 [Ca2 + ]i 平衡失调 ,而 [Ca2 + ]i 的升高可引起兴奋性毒性反应、自由基损伤、Tau蛋白的积聚和过度磷酸化、Aβ的毒性增大、激活Cal pain以及诱发细胞凋亡。该文综述了最近关于钙平衡失调假说的有关进展。

Objective To study the protective effects of scopolamine (Sco) (a muscarinic receptor antagonist) on rabbits with acute brain injury, and preliminarily explore the roles of acetylcholine (ACh) in the early pathologic changes of traumatic brain injury(TBI). Methods The model of acute brain injury was established by a free-falling device, and the rabbits received Sco intraperitoneally at 5 minutes and 2 hours after brain injury respectively. Transcranial Doppler (TCD) was used to monitor cerebral blood flow...

Objective To study the protective effects of scopolamine (Sco) (a muscarinic receptor antagonist) on rabbits with acute brain injury, and preliminarily explore the roles of acetylcholine (ACh) in the early pathologic changes of traumatic brain injury(TBI). Methods The model of acute brain injury was established by a free-falling device, and the rabbits received Sco intraperitoneally at 5 minutes and 2 hours after brain injury respectively. Transcranial Doppler (TCD) was used to monitor cerebral blood flow velocity (CBV) and pulsatility index (PI) of middle cerebral artery (MCA). The levels of Ca 2+ , the activities of superoxide dismutase (SOD), the contents of malondiadehyde (MDA) and Evans blue (EB) were measured, and the pathological changes were observed in brain tissue. Results This model consisted with the pathologic changes of accelerated brain injury. Sco reduced the levels of Ca 2+ , EB and MDA, increased the activities of SOD, and improved cerebral blood flow following brain injury. Conclusions In the early stage of brain injury, ACh can cause neuron calcium overload, oxide free radical reaction, cerebral vasospasm, and increase blood-brain barry(BBB) permeability. Scopolamine, a muscarinic receptor antagonist, can improve these pathologic changes. As a result, Sco has protective effects on brain tissue injury.

目的 :研究M受体拮抗剂东莨菪硷对兔急性脑损伤的保护作用 ,并初步探讨乙酰胆碱 (ACh)在创伤性脑伤早期病理变化中的作用。方法 :用自由落体打击器制作兔脑外伤模型 ,并于伤后 5min ,2h腹腔注射东莨菪硷 ,用经颅多谱勒监测大脑中动脉血流速度和搏动指数的变化 ;取脑组织检测Ca2 +、伊文思蓝 (EB)、超氧化物歧化酶 (SOD)、丙二醛 (MDA) ,并作病理检查。结果 :病检证实本模型符合临床所见加速性脑损伤的病理变化 ,东莨菪硷可降低兔脑外伤后脑组织中Ca2 +,MDA ,EB含量 ,升高SOD ,增加脑血流。结论 :脑外伤后早期ACh可致神经元钙超载、氧自由基反应、脑血管痉挛和血脑屏障 (BBB)通透性增强 ,M受体拮抗剂东莨菪硷可改善这些病理变化 ,具有脑保护作用

OBJECTIVE This study examined the variation of fluorescent intensity of neuron dissociative calcium in hippocampus as to explore the effects of different protective methods with DHCA and correlate the effects of calcium over loading to the neuron injury. METHODS Sixteen pigs (22~25 kg) were divided randomly into four groups, and 4 in each group group Ⅰ DHCA; group Ⅱ ACP; group Ⅲ RCP; group Ⅳ RCP+Nim. All animals were cooled 90 minutes at 18 degrees ℃ (pharyngeal) for 90 min and then rewarmed...

OBJECTIVE This study examined the variation of fluorescent intensity of neuron dissociative calcium in hippocampus as to explore the effects of different protective methods with DHCA and correlate the effects of calcium over loading to the neuron injury. METHODS Sixteen pigs (22~25 kg) were divided randomly into four groups, and 4 in each group group Ⅰ DHCA; group Ⅱ ACP; group Ⅲ RCP; group Ⅳ RCP+Nim. All animals were cooled 90 minutes at 18 degrees ℃ (pharyngeal) for 90 min and then rewarmed 120 minutes to 36℃. Left hippocampi were removed and then dissociated. These dissociated cells were stained with Fluo 3 and then measured with Flow Cytometry to analyze the variation of fluorescent intensity of neuron dissociative calcium. The mitochondrial ultrastructure changes were examined by electron microscope. RESULTS Free calcium fluorescent intensity was higher in group Ⅰ than in the other three groups; group Ⅲ was higher than group Ⅱ. There were no significant difference between group Ⅱ and group Ⅳ; group Ⅲ and group Ⅳ. (P=0.05) Accordingly, the severest injuries of mitochondria were found in group Ⅰ and the mildest in group Ⅱ. CONCLUSIONS Neuron calcium overload after DHCA, ie severe injuries of mitochondria was probably relative to central nerve system dysfunction. ACP could protect brain best by decreasing calcium overload ie milder injuries of mitochondria. RCP could also depress calcium overload and alleviate mitochondrial injury. But its effect was less than ACP. Nimodipine depressed partly calcium influx by blocking up VDCC (voltage dependent calcium channel) and enhanced the effect of RCP. But its effect was nonremarkable.

目的 通过观察海马区神经元细胞内 Ca2 +荧光强度的变化 ,说明 DHCA时不同脑保护方法对细胞内游离钙离子浓度的影响 ,并证明细胞内钙超载在神经元损伤中的作用。方法 北京农业大学实验用小型猪 16头 ,体重 2 2 kg~ 2 5 kg。鼻咽温降至 18℃时分别给予如下处理 90 m in:DHCA( 组 ) ,ACP( 组 ) ,RCP( 组 ) ,RCP+Nim ( 组 )。复温 12 0 m in至鼻咽温 3 6℃。取左侧海马头部制备细胞悬液 ,Fluo- 3染色 ,应用流式细胞仪分析细胞内 Ca2 +荧光强度的变化情况。电镜观察神经元线粒体超微结构的变化。结果 细胞内 Ca2 +荧光强度 组明显高于其他 3组 , 组明显高于 组 , 组和 组、 组和 组之间无显著差异 (显著性界值 P =0 .0 5 )。与之相应 ,线粒体损伤 组最重 , 组最轻。结论  DHCA时神经元内钙超载 ,线粒体损伤严重 ,可能与 DHCA后中枢神经系统功能障碍有关 ;ACP明显减轻细胞内钙超载 ,线粒体损伤轻 ,脑保护作用效果理想 ;RCP亦能减轻细胞内钙超载、减轻线粒体损伤 ,但作用不及 ACP;Nim通...

目的 通过观察海马区神经元细胞内 Ca2 +荧光强度的变化 ,说明 DHCA时不同脑保护方法对细胞内游离钙离子浓度的影响 ,并证明细胞内钙超载在神经元损伤中的作用。方法 北京农业大学实验用小型猪 16头 ,体重 2 2 kg~ 2 5 kg。鼻咽温降至 18℃时分别给予如下处理 90 m in:DHCA( 组 ) ,ACP( 组 ) ,RCP( 组 ) ,RCP+Nim ( 组 )。复温 12 0 m in至鼻咽温 3 6℃。取左侧海马头部制备细胞悬液 ,Fluo- 3染色 ,应用流式细胞仪分析细胞内 Ca2 +荧光强度的变化情况。电镜观察神经元线粒体超微结构的变化。结果 细胞内 Ca2 +荧光强度 组明显高于其他 3组 , 组明显高于 组 , 组和 组、 组和 组之间无显著差异 (显著性界值 P =0 .0 5 )。与之相应 ,线粒体损伤 组最重 , 组最轻。结论  DHCA时神经元内钙超载 ,线粒体损伤严重 ,可能与 DHCA后中枢神经系统功能障碍有关 ;ACP明显减轻细胞内钙超载 ,线粒体损伤轻 ,脑保护作用效果理想 ;RCP亦能减轻细胞内钙超载、减轻线粒体损伤 ,但作用不及 ACP;Nim通过阻断电压依赖性钙通道 ,部分抑制了 Ca2 +内流 ,加强了 RCP的作用 ,但效果一般

 
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关neuron calcium的内容
在知识搜索中查有关neuron calcium的内容
在数字搜索中查有关neuron calcium的内容
在概念知识元中查有关neuron calcium的内容
在学术趋势中查有关neuron calcium的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社