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portal blood
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  门静脉血
     The free cancer cells in portal blood were more than those in peripheral blood (1.81% VS 0.42%,P<0.01).
     胃癌组门静脉血中游离癌细胞阳性率高于外周血(1.81%VS0.42%,P<0.01)。
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     Conclusion Portal blood flow measurements using Cine PC MRI closely reflect physiologic conditions.
     结论MRI Cine PC在正常呼吸情况下对门静脉血流行定量测量,接近人体生理状态,适合门静脉血流测量;
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     The level of portal blood D-lactate, TNF-α and intestinal mucosa MDA at T_(0) and T_(1) was significantly higher (P<0.05, or P<0.01). The histologic damage in the intestinal mucosa was observed in Group B, and the rat survival in Group B was lower than that in Group A (P<0.05).
     T0,T1门静脉血D-乳酸,TNF-α及肠黏膜MDA含量明显升高(P<0.05),B组肠黏膜光镜及电镜下存在明显组织学损害,48h生存率明显低于A组(P<0.05)。
短句来源
     Blood sample(10 ml) of peripheral venous were obtained in each pig before liver resection and after resection at the following time 5 min、30 min、12 h、24 h、48 h、72 h and 7 d. Sample of portal blood(10 ml) were also obtained at 5 and 30 min after resection,each sample was assayed TNF α.
     所有动物于切肝前、切肝后 5min、切肝后 30min ,取外周静脉血及门静脉血检测TNF α(tumornecrosisfactor,TNF α) ,并于切肝后 12h、2 4h、4 8h、72h及 7d取外周静脉血检测ALT及TNF α。
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     The plasma nitrite and nitrate (NO2 NO3) anionic ratio was detected and the portal blood flow(PBF), heart rate (HR) and mean blood pressure (MBP) were measured in 72 patients with liver cirrhosis and in30 normal persons in order to study relationship between nitric oxide (NO) and hyperdynamic circulation in cirrhosis.
     对72例肝硬化患者和30例正常人血浆NO2/NO3水平和门静脉血流量、心率与平均血压进行测定,探讨NO与肝硬化高动力循环之间的关系。
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  门脉血
     It is found that the values of portal blood flow in 10 schistosome-infected rabbits and 8 normal rabbits were 34.4 ±7.3ml/min and 66.9 ±5.5ml/min respectively,the difference being statistically signifi-cant.
     血吸虫病性肝硬变兔组门脉血流量为34.4±7.3ml/min,正常兔组门脉血流量为66.9±5.5ml/min,P<0.01,两者相差显著。
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     Results:The CEA level in the peripheral blood of 18 patients with colorectal cancer was much lower than that in the portal blood( P <0.01),and the CEA level in the peripheral blood of 16 cases was much higher than that in the portal blood( P <0.01).
     结果 :18例患者外周血CEA值低于门脉血 (P <0 .0 1) ,16例患者外周血CEA值高于门脉血 (P <0 .0 1)。
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     The results show that the portal blood endotoxin level is significantly higher than the systemic blood endotoxin level(P<0.001)in control group.
     结果对照组门脉血内毒素水平明显高于外周血内毒素水平(P<0.001)。
短句来源
     The results show that the portal blood endotoxin level is significantly higher than the systemic blood endotoxin level (P<0.001) in control group.
     结果对照组门脉血内毒素水平明显高于外周血内毒素水平(P<0.001)。
短句来源
     Methods:The CEA in the peripheral and portal blood of 34 patients with colorectal cancer was detected by monoclonal antibody radioimmunoimaging.
     方法 :采用单克隆抗体放射显影法 ,对 34例结直肠癌患者手术时抽取外周血与门脉血作CEA检测。
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  “portal blood”译为未确定词的双语例句
     The portal blood flow velocity increased from 11.6±3.8 cm/s to 43.5±13.2 cm/s(P<0.01).
     门脉血流速度(43.5±13.2)cm/s与术前的(11.6±3.8)cm/s比较;
短句来源
     Subsequently,2 mL of 5% glucose solution was injected into the intestinal lumen and the glucose concentrations of portal blood were determined at 0,15,30,45,60 min after the injection.
     取材后向小肠内注入5%葡萄糖溶液2 mL,分别测定0,15,30,45和60 min门静脉血糖浓度。
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     Propranolol plus ISMN caused a marked reduction in portal blood flow, from 711.76 ± 515.52 to 484.02 ± 222.93 ml/min (P<0.0l);
     采用同个体自身治疗前后对照研究。 结果表明应用普萘洛尔与ISMN治疗1周后,Dpv、Vpv均显著性下降(P<0.01),Opv也显著性降低(711.76±515.52 vs 484.02±222.93)mL/min,P<0.01;
短句来源
     Results Of the 504 patients examined, the median velocity of the portal blood flow was 46.27 cm/s (range: 15.8 to 110.8) on the day of the operation.
     结果术后当日门静脉平均血流速度为46.27 cm/s,最小流速为15.8 cm/s,最大流速为110.8 cm/s。
短句来源
     Results The area of the portal trunk and portal blood flow velocity showed no marked changes in patients with hepatic fibrosis, with the value 152.25±24.60mm 2 and 11.90±1.23cm/s, respectively. But the portal blood flow volume was significantly increased to 17.99±2.67ml/s.
     结果 肝纤维化患者门脉主干截面积和平均血流速度无明显改变 (分别为 15 2 .2 5± 2 4.60mm2 和 11.90± 1.2 3cm/s) ,但门脉血流 ( 17.99± 2 .67ml/s)显著增加。
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  portal blood
The portal blood flow was reduced by one-third of that before shunt.
      
Fructoselysine appeared in the portal blood very late compared to amino acids resulting from a very slow release and corresponded to 8.2 and 18.6 % of the ingested amount after 12 and 72h, respectively.
      
Significant changes of the appearance in the portal blood were observed only for lysine (-60 %), alanine (-17 %) and cystine (+37 %).
      
Uptake of radiolabeled copper from portal blood containing fructose or glucose
      
In the liver the periportal necrosis is probably a direct cytopathic effect of the highest levels of iron carried to these cells by the portal blood flow.
      
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The present paper reports the use of colorimetric method to determine the blood level of F-30066 in portal vein and heart in rabbits. By spectrophotometry, paper and column chromatography, the metabolites of F-30066 in the intestine and urine of the host were investigated.The therapeutic effect of the drug as shown by different routes of administration, including the oral route, was compared. Owing to the absorption of F-30066 in the gastro-intestinal tract, a certain concen- tration of the drug was found in...

The present paper reports the use of colorimetric method to determine the blood level of F-30066 in portal vein and heart in rabbits. By spectrophotometry, paper and column chromatography, the metabolites of F-30066 in the intestine and urine of the host were investigated.The therapeutic effect of the drug as shown by different routes of administration, including the oral route, was compared. Owing to the absorption of F-30066 in the gastro-intestinal tract, a certain concen- tration of the drug was found in the portal blood, F-30066 could be decomposed in liver, a part of it being re-excreted into intestine after inactivation.The transformation pro- ducts did not show any effect on schistosomes in mice. After oral administration of F-30066, two metabolites were detected in urine. None of them showed any killing effect on schistosome. When the solution of F-30066 was exposed to diffused sunlight, the drug was de- composed and became inactive. When 15 mg/kg of F-30066 in suspension were given intravenously to rabbits three times daily for 14 days, no therapeutic effect was observed. When a dose of 45 mg/kg of this drug was administered intramuscularly once daily for 10 days, the result was disappointing.F-30066 was still found at the site of injec- tion four weeks later. Intraperitoneal injection of 4 mg/20 g of F-30066 to mice did produce a satisfactory response; its blood content determined 1/2, 1, and 2 hours after injection was found to be 8.2, 2.2, and 1.6 μg/ml respectively.Neither intravenous nor intramuscular injection could result in such a high level.It seemed likely that the therapeutic effect of F-30066 was closely related to the concentration in blood.

本文利用比色法测定了家兔门静脉血液及心脏血内呋喃丙胺(F30066)的含量.应用光谱分析,纸层析及柱层析法研究了宿主肠道内及尿内呋喃丙胺代谢产物.采用实验治疗血吸虫病的方法,比较胃肠道外不同给药途径的治疗效果.家兔口服呋喃丙胺经胃肠道吸收后,在门静脉血液内有一定浓度的药物.此药经过肝脏转化后部分排泄入肠道.此肠内转化物无治疗血吸虫病的效用.口服呋喃丙胺后尿内可发现二个药物的代谢产物.经体内、体外试验此二代谢产物,均无杀死血吸虫的作用.静脉、肌肉注射呋喃丙胺混悬液治疗血吸虫病家兔都无疗效.腹腔注射呋喃丙胺治疗小白鼠血吸虫病却获得良好效果.

After administration of pyquiton (Praziquantel, Embay 8440) to rabbits, the drug was determined directly, either in the biological sample or after extraction of the active compound with chloroform. By placing schistosomes into an aliquot of the diluted biological sample, a criterion is obtained whetherthe concentration of the drug is above or below the threshold that produces stimulation and contraction of the worms. The limit of sensitivity is 0.005 /μg/ml.When pyquiton was injected into various segments of...

After administration of pyquiton (Praziquantel, Embay 8440) to rabbits, the drug was determined directly, either in the biological sample or after extraction of the active compound with chloroform. By placing schistosomes into an aliquot of the diluted biological sample, a criterion is obtained whetherthe concentration of the drug is above or below the threshold that produces stimulation and contraction of the worms. The limit of sensitivity is 0.005 /μg/ml.When pyquiton was injected into various segments of the alimentary canal of rabbits, the drug was best absorbed from the duodenum and ileum, relatively so from the rectum and much less from the colon or stomach. After absorption from the small intestine, the pyquiton plasma level in the peripheral venous blood was about tenfold lower than that in the portal blood.After oral or subcutaneous application of pyquiton at the respective dosages of 100 mg/kg and 20 mg/kg, the plasma levels were about the same. The drug was absorbed rapidly and maximal plasma level was reached within 1 to 1.5 hours. After intramscular injection the concentration of pyquiton in the plasma was higher than that after subcutaneous administration. A rather high plasma level was obtained just after intravenous injection, but the drug was rapidly eliminated from the blood.No accumulation of the drug in plesma was observed when pyquiton was given orally to rabbits once daily for 3 days. With repeated oral doses at 4-hour intervals, distinctly higher dose-dependent plasma levels were obsarved after the second and third doses than after the first.After oral administration to rabbits, pyquiton was rapidly distributed in all organs tested. However, higher concentrations of drug in stomach and small intestine were found 0.5 to 4 hours after administration. It was eliminated in 24 hours from most organs, leaving only trace amounts in stomach and intestine. Biological activity was detectable in rabbits urine and faeces after administration of pyquiton.

用以血吸虫为标本的生物鉴定法,观察了抗血吸虫新药吡喹酮在家兔体内的代谢。自家免胃肠道的不同部位注入吡喹酮时,以小肠的吸收最好,直肠次之,而结肠和胃则较差。药物自小肠吸收后,周围静脉血浆的药浓度较门静脉的低10倍以上。家兔口服吡喹酮100mg/kg的血浆药浓度与皮下注射20mg/kg的相仿;肌肉注射吡喹酮20mg/kg的血浆药浓度较皮下注射的为高;若静脉注射相同剂量,则于注射完毕时虽有甚高的血药浓度值,但药物可迅速自血浆中消除。吡喹酮多次给药时无积蓄作用;若每4小时给药一次,连给3次,则可依次增加血浆的药浓度。家兔一次口服吡喹酮30分钟~4小时,以胃、小肠组织的含药量较高,肝、肾和脑等次之。给药后24小时,除胃和小肠外,其余脏器组织中的药物均已消除。此外,自服药兔的粪、尿中检获有生物活性的物质。

It has been concerned by the people for a long time to unfold the interruption of hepatic blood flow in security. The present work was undertaken for the clinical practice. 59 heathy adult rabbits were used in this study. These animals were divided into three groups; (1) ligating the right branch of the hepatic artery, (2) ligating tne right branch of the portal vein, and (3) ligating both the right branch of the hepatic artery and portal vein. The hepatic weight, histology, ultrastructure and serum enzymes...

It has been concerned by the people for a long time to unfold the interruption of hepatic blood flow in security. The present work was undertaken for the clinical practice. 59 heathy adult rabbits were used in this study. These animals were divided into three groups; (1) ligating the right branch of the hepatic artery, (2) ligating tne right branch of the portal vein, and (3) ligating both the right branch of the hepatic artery and portal vein. The hepatic weight, histology, ultrastructure and serum enzymes were observed at regular intervals after the operation. Vaso-graphys were also performed in the selected animals to investigate reconstruction of collateral vessels.The experiment results;1. During the earlier stage after the ligation of the right hepatic artery, in-farct areas of various extent were occurred in the lobe from which the arterial blood supply had been excluded. Finally, they can be classified into two types, the restored type (55.6%) and the infarction type (44.4%). After the ligation of the right portal vein, the ligated lobes became atrophic, and nonligated lobes became compensatory hepertrophic, and by a balance of the two processes the original weight of the liver was maintained. After the ligation of both the right branch of the hepatic artery and portal vein, the infarction was total in lobes supplied by the occluded vessels in 83 per cent of animals. There were partial normal liver tissues remained only in three rabbits.2.On the third postoperative day, the serum GPT activity rose much higher in the animals of 3 rd group than that in the 1 st or 2 nd group.3.The collateral circulation was reconstructed at the 25 th day after ligating the right hepatic artery, while there was no collateral circulation reconstructed after ligating the right portal vein.4.The rabbits could tolerate about 20 per cent of acute infarction of liver tissues.The authors are conveined that;1.There were some dangerous after the ligation of the hepatic artery. The extent of hepatic infarction may be reduced after interrupting the hepatic arterial flow if we could take some methods to alter the stagnation of portal blood flow and to enhance the hepatic cell against hypoxymia.2.The ligation of the branch of the portal vein may be practiced in the clinic. There was no bad result to the organism.3.The ligation of both the branch of the hepatic artery and portal vein should not be performed, and this may lead to severe consequence.4.In the early period after operation dynamic observating the serum GPT activity may be used to evaluate the degree of the liver damage.

安全开展肝血流阻断术是人们关注的问题。为指导临床工作,本实验共用59只家兔进行研究。分3个实验组,分别或同时结扎肝动脉、门静脉右叶分枝,观察术后肝脏重量、组织学、超微结构及血清酶活性的变化,並选择性作血管造影,了解血流阻断情况。 实验结果为:1.肝动脉分枝结扎后早期,结扎叶均发生不同程度的梗死。总的趋势可分为两型:恢复型(占本组55.6%)和梗死型(占本组的44.4%);门静脉分枝结扎后引起结扎叶的萎缩、非结扎叶代偿性肥大,两者处于相对的平衡状态;两种血管同时被结扎后,83%动物的梗死区占据整个结扎叶,仅3只残留有部分色泽尚正常的肝组织。 2.肝动脉、门静脉分枝同时结扎组与单个血管结扎组比较,术后第3天血清GPT活性相差显著(P<0.01)。 3.肝动脉分枝结扎后第25天,动脉侧枝循环已经建立,门静脉分枝结扎后则未见入肝的侧枝循环形成。 4.20%左右肝组织发生急性梗死对于家兔是可以耐受的。 本文认为:1.肝动脉结扎术存在一定的危险性。在肝动脉血流完全阻断情况下,从术前、术中开始提供改善门静脉血流淤滞状态、增强肝细胞对低氧血症抵抗力的措施可以减轻术后肝梗死的严重程度。 2.门静脉分枝结扎对机体不产生严重的影响...

安全开展肝血流阻断术是人们关注的问题。为指导临床工作,本实验共用59只家兔进行研究。分3个实验组,分别或同时结扎肝动脉、门静脉右叶分枝,观察术后肝脏重量、组织学、超微结构及血清酶活性的变化,並选择性作血管造影,了解血流阻断情况。 实验结果为:1.肝动脉分枝结扎后早期,结扎叶均发生不同程度的梗死。总的趋势可分为两型:恢复型(占本组55.6%)和梗死型(占本组的44.4%);门静脉分枝结扎后引起结扎叶的萎缩、非结扎叶代偿性肥大,两者处于相对的平衡状态;两种血管同时被结扎后,83%动物的梗死区占据整个结扎叶,仅3只残留有部分色泽尚正常的肝组织。 2.肝动脉、门静脉分枝同时结扎组与单个血管结扎组比较,术后第3天血清GPT活性相差显著(P<0.01)。 3.肝动脉分枝结扎后第25天,动脉侧枝循环已经建立,门静脉分枝结扎后则未见入肝的侧枝循环形成。 4.20%左右肝组织发生急性梗死对于家兔是可以耐受的。 本文认为:1.肝动脉结扎术存在一定的危险性。在肝动脉血流完全阻断情况下,从术前、术中开始提供改善门静脉血流淤滞状态、增强肝细胞对低氧血症抵抗力的措施可以减轻术后肝梗死的严重程度。 2.门静脉分枝结扎对机体不产生严重的影响,这种手术方式是安全的,在临床上可以开展。 3.同时结扎肝动脉、门静脉肝叶

 
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