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female genital tracts infection
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  女性泌尿生殖道感染
     BACKGROUND: Ureaplasma urealyticum may cause female genital tracts infection and lead sterility,infertility and spontaneous abortion. But it still is not clear whether Ureaplasma urealyticum is one of the factors responsible for fetal malformation.
     背景:解脲脲原体引起女性泌尿生殖道感染可导致不育不孕和自然流产,但其是否为导致胎儿畸形的因素之一尚不十分清楚。
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Objective To study the prevalence of female genital tract infection diseases and the relative risk factors,so as to find a intervention strategy.Methods 1111 investigated population from gynecologic clinic patients,family planning clinic patients,workers,farmers,officers who had routine gynecologic examination in our hospital and prostitutes women who had commercial sexual activity were given questionnaires including occupation,education,economic status,marriage,personal hygiene,sexual...

Objective To study the prevalence of female genital tract infection diseases and the relative risk factors,so as to find a intervention strategy.Methods 1111 investigated population from gynecologic clinic patients,family planning clinic patients,workers,farmers,officers who had routine gynecologic examination in our hospital and prostitutes women who had commercial sexual activity were given questionnaires including occupation,education,economic status,marriage,personal hygiene,sexual activity and hygiene.Pelvic examination and laboratory tests were taken at the same time.Results The average age of 1111 cases was (32\^7±8\^85)years old.The personal hygiene during the menstruation was bad especially in farmers(P<0\^01).The average age of first coition was 23\^6,earlier than the average marriage age 24\^4.In the prostitutes group the earlier coition,the more sexual intercourse per week,multiple sex partners,bad sexual hygiene,multiple coition methods were more common than other groups(P<0\^01).The rate of suffering general gynecological inflammation diseases for all groups was 97\^7%,the highest was cervicitis(56\^0%),the following was vulvitis and vaginitis 35\^6%,pelvic inflammation diseases(PID)6\^1%.The incident of STD for all was 52\^7%,the highest was trichomonas vaginitis 11\^7%,the following was gonorrhea 9\^4%,hepatitis B 8\^0%,chlamydia 7\^8%,human papilloma virus 5\^7%,candida albicans 4\^0%,cytomegalovirus 2\^7%,human herpes virus 2\^3%,ureaplasma urealyticum 1\^1%.The positive rates of general gynecological inflammation diseases and STD in prostitutes group were higher than that of other groups(P<0\^01)and this group had characteristics of low education,servers in occupation,high proportion of abortion before marriage,multiple general gynecological inflammation diseases and STD infection.Conclusion The general gynecological inflammation diseases and STD are important diseases among women's psychological and physical health.The occurrence of these diseases has close relationship with occupation,personal hygiene,sexual hygiene and sexual morality.The strategy for prevention is early diagnosis and treatment and stopping the path of transmission.

目的 为进一步了解女性生殖道感染性疾病的发病情况及影响发病的相关因素 ,提出防治疾病的干预措施。方法  1111例来自妇科门诊病人、早孕要求终止妊娠妇女、来本院健康体检的工人、农民、机关干部及性乱妇女 ,通过问卷调查了解其职业、受教育情况、经济状况、卫生习惯、性卫生习惯等情况 ,同时对每位妇女进行常规妇科检查及有关病原体实验室检查。结果  1111例妇女年龄范围为 15~ 6 6岁 ,平均 (32 7± 8 85 )岁。经期使用不消毒月经垫、不洗外阴者分别占 5 7%及 19 9%。卫生习惯以农民组较差 (P <0 0 1)。平均初次性生活年龄为 2 3 6岁 ,小于平均结婚年龄 2 4 4岁。婚前性生活经历尤以性乱组明显 (P <0 0 1) ,性生活频繁、多个性伴侣、性交前后不清洗外阴及口交、肛交等多样性交方式也以性乱组比例最高 (P <0 0 1)。生殖道普通炎症患病率为 97 7% ,以宫颈炎症性疾病为主 ,为 5 6 0 % ,其次为外阴阴道炎、盆腔炎 ,分别为 35 6 %及 6 1%。性传播疾病 (STD)检出率平均为 5 2 7% ,以滴虫为主 ,为 11 7% ,其次为淋病...

目的 为进一步了解女性生殖道感染性疾病的发病情况及影响发病的相关因素 ,提出防治疾病的干预措施。方法  1111例来自妇科门诊病人、早孕要求终止妊娠妇女、来本院健康体检的工人、农民、机关干部及性乱妇女 ,通过问卷调查了解其职业、受教育情况、经济状况、卫生习惯、性卫生习惯等情况 ,同时对每位妇女进行常规妇科检查及有关病原体实验室检查。结果  1111例妇女年龄范围为 15~ 6 6岁 ,平均 (32 7± 8 85 )岁。经期使用不消毒月经垫、不洗外阴者分别占 5 7%及 19 9%。卫生习惯以农民组较差 (P <0 0 1)。平均初次性生活年龄为 2 3 6岁 ,小于平均结婚年龄 2 4 4岁。婚前性生活经历尤以性乱组明显 (P <0 0 1) ,性生活频繁、多个性伴侣、性交前后不清洗外阴及口交、肛交等多样性交方式也以性乱组比例最高 (P <0 0 1)。生殖道普通炎症患病率为 97 7% ,以宫颈炎症性疾病为主 ,为 5 6 0 % ,其次为外阴阴道炎、盆腔炎 ,分别为 35 6 %及 6 1%。性传播疾病 (STD)检出率平均为 5 2 7% ,以滴虫为主 ,为 11 7% ,其次为淋病 9 4%、乙肝病毒感染 8 0 %、衣原体7 8%、人乳头状瘤病毒 5 7%、白色念珠菌感染 4 0 %、巨细胞病毒 2 7%、单纯疱疹病毒 2 3%、脲支原体 1 1%。普通妇科炎症及STD患病率均以性

Objective: To observe effect of IUD with thread on female genital tract infections among childbearing age women. Methods:1762 women with IUDs were divided into two groups. Women taking IUD with thread (876 cases) were in group A, and those taking IUD without thread (886 cases) were in group B. Laboratory test of vaginal secretion (including pathogen) was taken and cervical cell morphology was observed 3,6,12,24,36 months after IUD insertion respectively. Result:There was no significant...

Objective: To observe effect of IUD with thread on female genital tract infections among childbearing age women. Methods:1762 women with IUDs were divided into two groups. Women taking IUD with thread (876 cases) were in group A, and those taking IUD without thread (886 cases) were in group B. Laboratory test of vaginal secretion (including pathogen) was taken and cervical cell morphology was observed 3,6,12,24,36 months after IUD insertion respectively. Result:There was no significant difference between two groups 3 months after insertion (P>0.05). But 6 months later, the rate of abnormal leucorrhoea and pathogen as well as squamous epithelium in group A was higher than that in group B (P<0.05). Conclusion :Although IUD with thread may have better contraceptive effect, it increase the rate of abnormal leucorrhoea and pathogen. Sometimes it also affect the quality of sex between husband and wife. So it needs more attention and improvement to better women's reproductive health.

目的:观察健康已婚育龄妇女放置宫内节育器后尾丝对其生殖道健康的影响。方法:采用实验室检测方法,对在本中心放置宫内节育器的1762例妇女(其中有尾丝IUD组876例、无尾丝IUD组886例),分别在置器后3、6、12、24、36个月进行阴道分泌物常规、病原体(支原体、衣原体)、病原菌(淋球菌、放线菌)、宫颈细胞形态学等检测观察。结果:置入3个月时,两组观察对象各项检查差异无统计学意义(P>0.05);6个月后,阴道分泌物常规异常、病原体以及中间型鳞状上皮细胞检出率,有尾丝组高于无尾丝组,且随置器时间的延长而增加,差异具有统计学意义(P<0.05)。结论:带尾丝型IUD虽可起到较好的避孕效果,但在置入6个月后出现不同程度的阴道分泌物及病原体异常,尾丝的粗硬度也不同程度影响着夫妻的性生活,应引起广大临床工作者高度重视,并不断完善IUD质量以提高妇女的生殖健康水平。

BACKGROUND: Ureaplasma urealyticum may cause female genital tracts infection and lead sterility,infertility and spontaneous abortion.But it still is not clear whether Ureaplasma urealyticum is one of the factors responsible for fetal malformation. OBJECTIVE:To investigate whether Ureaplasma urealyticum is one of the key factor responsible for fetal malformation. DESIGN:Non-randomized observation of compromised children and their parents with concurrent control. SETTING:The department of immunology and...

BACKGROUND: Ureaplasma urealyticum may cause female genital tracts infection and lead sterility,infertility and spontaneous abortion.But it still is not clear whether Ureaplasma urealyticum is one of the factors responsible for fetal malformation. OBJECTIVE:To investigate whether Ureaplasma urealyticum is one of the key factor responsible for fetal malformation. DESIGN:Non-randomized observation of compromised children and their parents with concurrent control. SETTING:The department of immunology and microbiology of a medical college. PARTICIPANTS:Totally 16 malformed fetuses(3 female and 13 male cases) and their parents were chosen from the family seeking pregnancy care in the Department of Gynecology and Obstetrics of the First Affiliated Hospital of Luzhou Medical College and Luzhou First People's Hospital from 1995 to 1997. METHODS:Ureaplasma urealyticum detection was performed in 16 samples of the umbilic blood of the malformed fetuses,sperms of the father,and cervical mucus of the mother who conceived the malformed fetus.The 11 couples positive for Ureaplasma urealyticum were treated with macrolides and aminoglycoside antibiotics and followed up for the outcome of the following pregnancy. MAIN OUTCOME MEASURES:The relation between Ureaplasma urealyticum infection and fetal malformation was examined. RESULTS:Totally 11 of the 16 umbilical blood samples(69%) were positive for Ureaplasma urealyticum,and serological tests of parents in the 11 positive cases detected rubella virus,cytomegalovirus or Toxoplasma gondii antibodies,nor was abnormality found in chromosomal examination.The following pregnancies and delivery were followed up in 4 women,and the babies showed no functional or organic abnormities with good development till the age of 2 years. CONCLUSION:Female genital tract Ureaplasma urealyticum infection is related to fetal malformation,which provides evidence to support interventions of the occurrence of fetal malformation.

背景:解脲脲原体引起女性泌尿生殖道感染可导致不育不孕和自然流产,但其是否为导致胎儿畸形的因素之一尚不十分清楚。目的:探讨解脲脲原体感染是导致胎儿畸形重要因素之一。设计:以患儿及其父母为研究对象,非随机化同期对照,观察对比研究。单位:一所医学院的微生物与免疫学教研室。对象:选择1995/1997由泸州医学院微免教研室对泸州医学院第一附属医院妇产科和泸州市第一人民医院妇产科门诊及住院16例畸形胎儿(女3例,男13例)及其父母为研究对象。方法:对16例畸形胎儿脐带血,畸形儿父亲的精液和异常妊娠产妇的宫颈黏液或阴道分泌物进行解脲脲原体分离。采用大环内酯类和氨基糖甙类抗生素对11例夫妇进行治疗,然后追踪再次妊娠及生育现象。主要观察指标:脲脲原体感染与胎儿畸形的关系。结果:16例中11例解脲脲原体阳性,阳性率为69%。11例解脲脲原体阳性者抗风疹病毒、抗巨细胞病毒、抗弓形抗体和染色体均未发现异常。已追踪到的4例再次妊娠结果、妊娠过程正常,新生儿发育良好,追踪观察到2岁未发现器质性和功能性异常。结论:女性生殖道解脲脲原体感染与胎儿畸形的发生有一定关系,从而为干预胎儿畸形发生提供理论依据。

 
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