助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   mouse hepatocyte 的翻译结果: 查询用时:0.009秒
图标索引 在分类学科中查询
所有学科
药学
更多类别查询

图标索引 历史查询
 

mouse hepatocyte
相关语句
  小鼠肝细胞
     INHIBITORY EFFECT OF 2 ( N ACETYL METHYL AMINO) 3′,4′ METHYLENEDIOXYACETYL AMINOPHENE(SY 640) ON COVALENT BINDING OF CARCINOGENIC BENZO(a)PYRENE WITH MOUSE HEPATOCYTE NUCLEAR DNA
     N-甲基(3,4-亚甲二氧基苯甲酰)甲基-乙酰胺(SY-640)对化学致癌剂苯并芘与小鼠肝细胞核DNA共价结合的抑制作用
短句来源
     Methods Full length mEndostatin was obtained with the technique of RT PCR and using mouse hepatocyte mRNA as template, pMD18T mEndostatin was sequenced automatically and an expression vector containing Egr 1 promoter, IFNγ, and endostatin genes was constructed with gene recombinant technique.
     方法 :利用逆转录多聚酶链反应法 (RT- PCR) ,以小鼠肝细胞 m RNA为模板 ,扩增获得全长 m Endostatin,与 p MD1 8T载体连接作全自动测序 ,并利用基因重组技术构建含 Egr- 1启动子的 IFNγ和m Endostatin双基因表达质粒。
短句来源
     Results:(1)The mouse hepatocyte appeared albuminous swelling and some nucleus of hepatocyte became smaller in hypoxia group.
     结果:(1)缺氧组小鼠肝细胞出现混浊肿胀,部分肝细胞核变小;
短句来源
     The Effects of Diverse Doses of Rifapentine on Mouse Hepatocyte Structure and the Activites of 10 Enzymes
     不同剂量利福喷丁对小鼠肝细胞结构和10种酶活性的影响
短句来源
     MATERIAL AND METHODS: Primary mouse hepatocyte culture was treated with30%of the lethal dose of13chemicals. 24hours after treatment,RNA was extracted and reverse transcribed to cDNA. The cDNA were detected by DNA microarray.
     材料与方法用30%的致死剂量染毒原代培养的小鼠肝细胞,24h后提取RNA,用芯片进行检测。
短句来源
更多       
  “mouse hepatocyte”译为未确定词的双语例句
     Results The suspension of fetal mouse hepatocyte can increase the expression of CD 3, CD 4 and CD 8,they were 40.74±2.95(P<0.01),37.53±4.88(P<0.02) and 24.99±2.74(P<0.05),respectively.
     结果 :鼠胎肝细胞悬液可以提高CD3 、CD4 、CD8的表达 ,分别为 4 0 74± 2 95 (P <0 0 1)、37 5 3± 4 88(P <0 0 2 )、2 4 99± 2 74 (P <0 0 5 ) ;
短句来源
     Inhibition of mouse hepatocyte apoptosis by anti-caspase-12 small interfering RNA
     抗小鼠 Caspase—12小干扰 RNA 对肝细胞凋亡的抑制作用
短句来源
     Influences of retrorsine on mouse hepatocyte proliferation after liver injury
     Retrorsine对小鼠肝损伤后肝细胞增殖的影响
短句来源
     The Effect of the Fetal Mouse Hepatocyte on the Immunological and Anti-comcer Functions of Mice Bearing S180 Sarcoma
     鼠胎肝细胞对S180荷瘤小鼠免疫功能影响及抗肿瘤作用的实验研究
短句来源
     The Influence of Pre-Treatment with pHGF on the Fas Antigen Expressions in Mouse Hepatocyte Demages Induced by Con-A
     pHGF对Con A诱导肝损伤小鼠的肝细胞Fas抗原表达的影响
短句来源
更多       
  相似匹配句对
     Mouse
     鼠标
短句来源
     A transgenic mouse that targets the expression of Cre recombinase in hepatocyte
     肝细胞特异性表达Cre重组酶转基因小鼠的建立
短句来源
     THE LION AND THE MOUSE
     狮子和老鼠
短句来源
     Objective To study the role of cycloheximide inducting hepatocyte apoptosis in mouse.
     目的 研究放线菌酮 (CHX)诱导小鼠肝细胞凋亡的作用机制。
短句来源
     The hepatocyte is bigger and polygonal.
     肝细胞较大,呈多边形,细胞间分界明显.
短句来源
查询“mouse hepatocyte”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  mouse hepatocyte
Previously we have shown that a nontumorigenic mouse hepatocyte line harboring simian virus 40 large tumor antigen (SV 40 TAg) could be converted to a full-malignant phenotype by transfection with HBV DNA.
      
L-Ethionine elevated AFP mRNA levels in primary mouse hepatocyte cultures; however, ethionine treatment also increased albumin mRNA levels in vitro.
      
The extinction, therefore, of mouse hepatocyte genes is attributed to the inhibitory action of the rat genome.
      
The deduced amino acid sequences revealed a strikingly high homology to a mouse hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs), but no homology to UDP-galactose: ceramide galactosyltransferase.
      
These results suggest that the ability to inhibit mouse hepatocyte intercellular communication is an effect specific to tumor promoters.
      
更多          


The activatory effect of the Mech extract of Chai Hu (Bupleurum Chinese DC) on adenylate cyclase in mouse hepatocyte preparation (ACHP) was reported by us. Recently we have been investigated that the isolation the active fractions of Chai Hu by monitoring its activatory or inhibitory activities on the ACHP. The results showed that the isolated of fractions of Chai Hu still has the activatory effect on the ACHP. We firstly found that two isolated fractions, named CH-5 and CH-7, have the inhibitory effects...

The activatory effect of the Mech extract of Chai Hu (Bupleurum Chinese DC) on adenylate cyclase in mouse hepatocyte preparation (ACHP) was reported by us. Recently we have been investigated that the isolation the active fractions of Chai Hu by monitoring its activatory or inhibitory activities on the ACHP. The results showed that the isolated of fractions of Chai Hu still has the activatory effect on the ACHP. We firstly found that two isolated fractions, named CH-5 and CH-7, have the inhibitory effects on the ACHP significantly. CH- 5 and CH- 7 inhibit the ACHP in a concentration dependent manner.

在柴胡甲醇提取物活化小鼠肝或腹水癌细胞腺苷环化酶(Ac)研究基础上,作者将柴胡的有效成分分离,用小鼠肝组织匀浆Ac活性为指标,鉴测分离组分的作用,结果发现:经分离的柴胡组分除有活化Ac作用外,并首次发现有抑制Ac的作用,其中两个组分有显著抑制Ac的作用,且成量效关系。

The activatory effect of the Mech extract of Chai Hu, Bupleurum Chinese DC, on adenylate cyclase in mouse hepatocyte preparation (ACHP) was reported by us Recently we have been investigated that the isolation of the active fractions of Chai Hu by monitoring its activatory or inhibitory activities on the ACHP. The results showed that the isolated fractions of Chai Hu still has the activatory effect on the ACHP. And we firstly founde that two isolated fractions, named CH-5 and CH-7, have the inhibitory effects...

The activatory effect of the Mech extract of Chai Hu, Bupleurum Chinese DC, on adenylate cyclase in mouse hepatocyte preparation (ACHP) was reported by us Recently we have been investigated that the isolation of the active fractions of Chai Hu by monitoring its activatory or inhibitory activities on the ACHP. The results showed that the isolated fractions of Chai Hu still has the activatory effect on the ACHP. And we firstly founde that two isolated fractions, named CH-5 and CH-7, have the inhibitory effects on the ACHP significantely. CH-5 and CH-7 inhibite the ACHP in a concentraction depentent manner.

我们曾报导柴胡甲醇提取物活化小鼠肝或腹水癌细胞腺苷酸环化酶(AC)的作用。近来,我们对柴胡进行有效成份分离,并用小鼠肝制备AC的活性为指标鉴测分离组分的作用。结果发现经分离的柴胡组分有活化AC的作用外,还首次发现柴胡组分有抑制AC的作用,其中两个柴胡组分有显著抑制AC作用,而且成量效关系。

Many carcinogens must be first transformed into electrophilic ultimate carcinogens via metabolic activation in liver microsomes before covalent binding to nucleophilic center of DNA. SY 640 is a synthetic compound with hepatoprotective activity. Results of the present study indicate that the covalent binding of 3H benzo(a)pyrine to mouse hepatocyte nuclear DNA in vitro and in vivo was markedly inhibited by SY 640. Further studies found that the liver microsomal cytochrome P 450 content...

Many carcinogens must be first transformed into electrophilic ultimate carcinogens via metabolic activation in liver microsomes before covalent binding to nucleophilic center of DNA. SY 640 is a synthetic compound with hepatoprotective activity. Results of the present study indicate that the covalent binding of 3H benzo(a)pyrine to mouse hepatocyte nuclear DNA in vitro and in vivo was markedly inhibited by SY 640. Further studies found that the liver microsomal cytochrome P 450 content and aminopyrine demethylase activity were significantly increased in mice treated with SY 640(150 mg·kg -1 po) once daily for three days, while the hepatic microsomal aminopyrine demethylase activity was obviously inhibited two hours after oral administration of SY 640 150 mg·kg -1 in mice. The aminopyrine demethylase activity of liver microsomes from normal, PB and 3 MC treated mice was also significantly inhibited by the addition of SY 640 in vitro . When SY 640 was incubated with NADPH reduced mouse liver microsomes, a metabolic intermediate(MI) complex at 457 nm was formed. The effects of SY 640 on cytochrome P 450 and its formation of MI complex with cytochrome P 450 may partially explain why SY 640 could inhibit covalent binding of BP to mouse hepatocyte DNA in vitro .

用小鼠肝细胞核制备和肝微粒体制备,研究了化合物SY640对致癌剂苯并芘(BP)损伤肝细胞核的保护作用及与P450的关系。结果表明,SY640可显著抑制3HBP与小鼠肝细胞核的DNA共价结合。SY640连续po3d,可显著诱导小鼠肝微粒体细胞色素P450含量及氨基比林脱甲基酶活性;给药1次2h内却只抑制氨基比林脱甲基酶活性。体外温孵实验表明,SY640对小鼠肝微粒体氨基比林脱甲基酶活性也具有明显的抑制作用。差示光谱分析表明,SY640可与细胞色素P450形成络合物。提示该化合物对肝微粒体细胞色素P450酶系的影响与其对化学致癌剂BP所致肝细胞毒性的保护作用有关。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关mouse hepatocyte的内容
在知识搜索中查有关mouse hepatocyte的内容
在数字搜索中查有关mouse hepatocyte的内容
在概念知识元中查有关mouse hepatocyte的内容
在学术趋势中查有关mouse hepatocyte的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社