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malignant mixed mesodermal tumor
相关语句
  恶性中胚叶混合瘤
     Expression of p53, epidermal growth factor receptor and Ki 67 antigen in uterine malignant mixed mesodermal tumor
     p53、EGFR和Ki-67抗原在子宫恶性中胚叶混合瘤中的表达
短句来源
     Purpose To study the correlation between expression of p53, EGFR, Ki 67 antigen and stage, histological grade and prognosis of uterine malignant mixed mesodermal tumor.
     目的:研究子宫恶性中胚叶混合瘤p53、EGFR和Ki-67抗原的表达及与肿瘤临床分期、组织学分级和预后的关系。
短句来源
     Malignant Mixed Mesodermal Tumor—Report of 3 Cases
     恶性中胚叶混合瘤(附三例报告)
短句来源
     Although the incidence of the malignant mixed mesodermal tumor in female genital tract is low. the malignancy is of high grade.
     女性生殖道恶性中胚叶混合瘤发病率低,恶性程度高。
短句来源
     The concrete types were carcinosarcoma(6 cases),stromal tumour(4 cases: malignance 3 case,incline to benign 1 case),spindle cell squamous carcinoma(2 cases),malignant mixed mesodermal tumor(2 cases),low malignance endometrial stroma sarcoma(2 cases),spindle cell synovial sarcoma(1 case),sarcomatoid carcinoma(1 case),neurilemmoma(1 case),leiomyosarcoma(1 case),malignant fibrous histiocytoma(1 cases).
     癌肉瘤6例,间质瘤4例(恶性3例,良性1例),梭形细胞鳞癌,恶性中胚叶混合瘤(癌肉瘤),低度恶性子宫内膜间质肉瘤各2例,梭形细胞滑膜肉瘤,肉瘤样癌,神经鞘瘤,平滑肌肉瘤,恶纤组各1例。 免疫组化:Keratin、EMA或CEA与V im分别表达不同形态瘤细胞8例。
短句来源
  “malignant mixed mesodermal tumor”译为未确定词的双语例句
     MALIGNANT MIXED MESODERMAL TUMOR OF THE UTERINE BODY AFTER RADIOTHERAPY FOR CARCINOMA OF UTERINE CERVIX: report of 15 cases
     宫颈癌放射治疗后发生的子宫中胚叶混合瘤15例报告
短句来源
     A clinical analysis of uterine malignant mixed mesodermal tumor
     子宫恶性混合性中胚叶肿瘤临床分析
短句来源
     Abstract15 patients with malignant mixed mesodermal tumor of the uterine body were found in12,973 cases of carcinoma of uterine cervix 5-27 years after radiotherapy with an incidence of0.12%.
     1958年至1988年放射治疗宫颈癌12973例,随诊4~34年,发现子宫中胚叶混合瘤15例,占宫颈癌放疗总数的0.12%。
短句来源
     Light and Electron Microscope Observation of a Malignant Mixed Mesodermal Tumor of the Ovary
     卵巢恶性中胚叶混合瘤的光镜和电镜观察
短句来源
  相似匹配句对
     MALIGNANT MIXED TUMOR OF SALIVARY GLAND
     唾腺恶性混合瘤——18例报导
短句来源
     Mixed malignant tumor of the urinary tract
     尿路复合性恶性肿瘤(附21例报告)
短句来源
     Malignant mixed Miiller's tumor: one case
     恶性混合性苗勒氏瘤1例
短句来源
     Three cases of malignant mixed mesodermal tumors
     原发卵巢恶性中胚叶混合瘤(附3例报告)
短句来源
     REPORTING OF PULMONARY MIXED MALIGNANT TUMOR IN 8 CASES
     肺混合性恶性肿瘤8例报道
短句来源
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  malignant mixed mesodermal tumor
We report here a case of a 62-years old woman with serous cystadenocarcinoma in the right ovary and a heterologous malignant mixed mesodermal tumor in the left one.
      
We report a patient with ovarian malignant mixed mesodermal tumor (MMMT) that produced immunoreactive human chorionic gonadotropin β-subunit (IR-hCGβ).
      
Ovarian malignant mixed mesodermal tumor producing the free form of the β-subunit of human chorionic gonadotropin
      
The authors conclude that this is the first case of malignant mixed mesodermal tumor with evident osteosarcomatous areas, described in the gallbladder.
      
In diagnosing a malignant mixed mesodermal tumor of the gallbladder it was imperative that we excluded malignant neoplasms with multiple histological patterns.
      
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Abstract15 patients with malignant mixed mesodermal tumor of the uterine body were found in12,973 cases of carcinoma of uterine cervix 5-27 years after radiotherapy with an incidence of0.12%. The radiation doses given were from 55-120 Gy to the area of uterine body. Fivepatients had vaginal discharge, 8 patients had mass in the lower abdomen and 5 had nosymptoms except an enlarged uterus. Four patients were diagnosed by endometrial biopsybefore treatment,11 by operation, 13 patients were treated by operation,...

Abstract15 patients with malignant mixed mesodermal tumor of the uterine body were found in12,973 cases of carcinoma of uterine cervix 5-27 years after radiotherapy with an incidence of0.12%. The radiation doses given were from 55-120 Gy to the area of uterine body. Fivepatients had vaginal discharge, 8 patients had mass in the lower abdomen and 5 had nosymptoms except an enlarged uterus. Four patients were diagnosed by endometrial biopsybefore treatment,11 by operation, 13 patients were treated by operation, 1 had by radiationand 1 no any treatment. All the 15 patients died of tumor. 13 patients died within 2 years. Itis believed that the malignant mixed mesodermal tumor of the uterine body is closely relatedto radiotherapy and the prognosis is poor. Therefore, in the follow-up examination, if vaginaldischarge and enlarged uterus are found, endometrial biopsy should be done to ensurecorrect diagnosis and early operation in order to obtain a better result.

1958年至1988年放射治疗宫颈癌12973例,随诊4~34年,发现子宫中胚叶混合瘤15例,占宫颈癌放疗总数的0.12%。平均年龄为63.3岁。潜伏期为5~27年。主诉为阴道排物者5例,下肢肿块5例,检查时发现的5例,15例均有子宫增大体征。治疗前经内膜活检证实者4/11例,11例经手术证实。手术治疗13例,放疗1例,未治1例。15例全部在5年内死于肿瘤,其中13例均死于治疗后2年内。

Although the incidence of the malignant mixed mesodermal tumor in female genital tract is low. the malignancy is of high grade. 29 cases of the malignant mixed mesodermal tumors of the female genital tract in the Gynecological and Obstetrical Hospital of Shanghai Medical University were presented in this paper from 1965 to 1 993,of them, 20 cases from endometrium, 2 from cervix, 6 from ovary, 1 from fallopian tube- They occupied about 0. 3 % of all patients hospitalized in gynecological department,...

Although the incidence of the malignant mixed mesodermal tumor in female genital tract is low. the malignancy is of high grade. 29 cases of the malignant mixed mesodermal tumors of the female genital tract in the Gynecological and Obstetrical Hospital of Shanghai Medical University were presented in this paper from 1965 to 1 993,of them, 20 cases from endometrium, 2 from cervix, 6 from ovary, 1 from fallopian tube- They occupied about 0. 3 % of all patients hospitalized in gynecological department, and about 5. 9 %. of all gynecological oncological patients during the same period in the hospital. The clinical manifestations were vagina bloody disoharge (74. 4% ) and aboominal pain (27. 6 % ). Diag nostic curettage is helptul to diagnosis for the patients with vagina bloedy discharge preoperativeIy, the success rate is 71 %. But it was insignificance in the patients without these symptoms. The prognosis of the tumor was poor, which 12 of 29 patients died within two years, only 7 of 29 patients lived more than five years. The prognosis of the malignant mixed rnesoclermal tumor of uterus may be better than the tumor of other fernale genital organs. The survival rate of five years is higher in patients after a complete surgery than those af-ter hyserectomy and bisalpingo-oophorectomy only. The effectiveness of chemotherapy is uncertain, but the use of the combined chemotherapy of the long-term, mainly in DDP, may lead to complete or partial remission.

女性生殖道恶性中胚叶混合瘤发病率低,恶性程度高。上海医科大学妇产科医院1965年~1993年共收治20例生殖道恶性中胚叶混合瘤,其中子宫20例,宫颈2例,卵巢6例,输卵管1例。占同期妇科住院患者的0.3‰、妇科肿瘤患者的5.9‰;。本病的临床表现主要有:阴道流血水(74.4%)、腹痛(27.6%)。在术前诊断中诊断性刮它对有阴道流血水的病例有一定帮助,确诊率为71%,而对拉他病例则意义不大。本病预后较差,29例中2年内死亡者12例。生存时间超过5年者7例。发生在子宫的恶性中胚叶混合瘤可能较发生在其他部位的预后好。五年存活率在较广泛的手术切除者比单纯全宫加双附件切除者要高。化疗对本病的治疗效果尚不肯定,但术后长期用以铂剂为主的联合化疗可得到明显缓解或完全缓解。临床分期与本病预后尚不明显。影响本病预后的可能因素有:1.手术治疗是否彻底。2术后是否加用以铂剂为主的联合化疗。3临床分期。

Purpose To study the correlation between expression of p53, EGFR, Ki 67 antigen and stage, histological grade and prognosis of uterine malignant mixed mesodermal tumor. Methods Expression of p53, EGFR and Ki 67 antigen were detected and compared by immunohistochemical S P method. Results The positive rates of p53, EGFR and Ki 67 were 61 9%、61 9% and 71 4% respectively. p53 overexpression was significantly more in stage Ⅱ ̄Ⅳ MMMT(10/15) than in stage Ⅰ (3/9) ( P <0 05). Histologically, there...

Purpose To study the correlation between expression of p53, EGFR, Ki 67 antigen and stage, histological grade and prognosis of uterine malignant mixed mesodermal tumor. Methods Expression of p53, EGFR and Ki 67 antigen were detected and compared by immunohistochemical S P method. Results The positive rates of p53, EGFR and Ki 67 were 61 9%、61 9% and 71 4% respectively. p53 overexpression was significantly more in stage Ⅱ ̄Ⅳ MMMT(10/15) than in stage Ⅰ (3/9) ( P <0 05). Histologically, there was more positive expression of p53 in grade Ⅱ carcinoma component than in the grade Ⅰ and EGFR expressed more in the grade Ⅲ sarcoma component than in the grade Ⅱ ( P <0 05). There was a significant difference of p53 staining between those cases who died within one year and those patients who survived for more than 2 years ( P <0 05), EGFR and Ki 67 antigen overexpressions in uterine MMMT were not associated with the stage and survival. Conclusion The expression of p53 was related to tumor stage and the pathological degree. The p53 expression has prognostic value.

目的:研究子宫恶性中胚叶混合瘤p53、EGFR和Ki-67抗原的表达及与肿瘤临床分期、组织学分级和预后的关系。方法:用免疫组化S-P法对21例子宫恶性中胚叶混合瘤的存档资料作染色观察。结果:p53、EGFR和Ki-67抗原的阳性表达率分别为61.9%、61.9%和71.4%。临床分期Ⅱ~Ⅳ期肿瘤(10/12)的p53阳性表达率明显高于Ⅰ期肿瘤(3/9)(P<0.05)、肿瘤癌性成分Ⅱ级的p53阳性表达高于Ⅰ期(P<0.05)。6例在1年内死亡的病例,其中5例p53阳性染色,而5例生存2年以上的肿瘤p53免疫染色全部阴性,两组比较(P<0.05)。肉瘤成分Ⅲ级的EGFR阳性率高于Ⅱ级(P<0.05),除此而外,EGFR和Ki-67的表达和肿瘤分期、预后均无相关性。结论:肿瘤的p53表达具有预后意义

 
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