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binding indices
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  结合指数
     The binding indices of ACA-IgM and IgA in these groups were significantly higher than the control group.
     与对照组比较,各组ACA-IgM、IgA结合指数均显著增高(P<0.001-0.05);
短句来源
     The ACA-IgG binding indices increased significantly in the group with gestational complications.
     妊娠并发症组ACA-IgG结合指数显著增高(P<0.001)。
短句来源
     The correlation was not significant between the neonate weight and ACA binding indices of the group of low birth weight ( P > 0.1). Comparing the patients with one kind of gestational complication and those with two kinds of gestational complications, no significant difference showed on ACA-IgM and IgG while significant difference showed on ACA-IgA.
     低体重儿组新生儿体重与ACA结合指数无显著相关性(P均>0.1),1种并发症和2种并发症患者间比较,ACA-IgM、IgG无显著性差异(P>0.1,P>0.05),ACA-IgA有显著性差异(P<0.001)。
短句来源
     Methods Binding indices of serum ACA-IgM, IgA and IgG were detected for 309 gravidas in third trimester by ELISA . The relationships between ACA in gravida serum and gestational complications, low birth weight of neonate, perinatal anoxia were analyzed respectively.
     方法 采用ELISA测定309名妊娠晚期妇女的血清ACA-IgM、IgA、IgG结合指数,观察孕妇血清ACA水平与妊娠并发症、新生儿低出生体重及围产儿缺氧的关系。
短句来源
     Results The changes of ACA binding indices happened mainly on IgM and IgA in the groups of gestational complications, low birth weight of neonate and perinatal anoxia.
     结果 妊娠并发症组、低出生体重组和围产儿缺氧组ACA结合指数的变化以IgM、lgA为主。
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  相似匹配句对
     XML Indices
     XML数据索引技术
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     protein binding;
     蛋白结合;
短句来源
     The ACA-IgG binding indices increased significantly in the group with gestational complications.
     妊娠并发症组ACA-IgG结合指数显著增高(P<0.001)。
短句来源
     Investigation of cord serum Retinal Binding protein and prealbumin as nutritional indices of Fetus
     新生儿脐血视黄醇结合蛋白和前白蛋白作为胎儿营养指标的探讨
短句来源
     On the Indices of Illite Crystallinity
     关于伊利石结晶度诸指数的评价
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  binding indices
Results: Binding indices did not differ between suicide victims and controls in either brain area and did not correlate with age.
      
Covalent binding of 13 monocyclic aromatic amines to hemoglobin was studied in female Wistar rats and hemoglobin binding indices were determined.
      
Binding indices in this case were 30±3 and 85±19, respectively.
      
(14C)-Labeled acetanilide and nitrobenzene were orally administered to female Wistar rats and binding indices [Binding(mmol/mol Hb)/Dose(mmol/kg)] determined; these were 12±1 and 73±10, respectively.
      
The b3a2 and b2a2 junction peptides had very low binding indices.
      
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Determination of serum anti-Borrelia burgdorferi antibody(A BB Ab) is a diagnostic aid useful in Lyme disease. Borrelia burgdorferi(BB) obtained from American Type culture was grown in modified Kelly medium. The spirochaetes were incubated at 35℃ for 5-7 days and the organisms were harvested by centrifugation and sonicated by sonicator. The sonicate was centrifuged. The supernatant was used as the antigen. The serum anti-BB Ab of 99 normal controls was measured by ELISA. 2SD above the nomal mean values of Binding...

Determination of serum anti-Borrelia burgdorferi antibody(A BB Ab) is a diagnostic aid useful in Lyme disease. Borrelia burgdorferi(BB) obtained from American Type culture was grown in modified Kelly medium. The spirochaetes were incubated at 35℃ for 5-7 days and the organisms were harvested by centrifugation and sonicated by sonicator. The sonicate was centrifuged. The supernatant was used as the antigen. The serum anti-BB Ab of 99 normal controls was measured by ELISA. 2SD above the nomal mean values of Binding Index (BI) of IgM and IgG anti-BB Ab were set as the upper limit for nomal value. The normal BI of IgM was 2.51 and that of IgG 2.85. The results were fairly stable. The coefficient of variation was less than 10 per cent.

用ELISA方法测定血清抗BB抗体是诊断Lgme病的唯一特异和灵敏的实验室手段。BB螺旋体1331接种于改良kelly培养基.置35℃孵育5~7天,经离心、冻融及超声破膜后为BB抗原。检测99例正常人血清抗BB抗体,IgM-BI及IgG-B1分别为2.51和2.85。此结果较稳定,重复性好,变异系数在10%以内。

Seiologic and pathologic studies of 24 cases with erythema chronicum migrans (ECM) were reported. The serum anti-Borrelia burgdorferi(BB) antibody was measured by ELISA in 24 cases with ECM. The Binding Indexes of IgM and IgG anti-BB antibodies were significantl increased in 20(83%)and 11(45%) out of the 24 cases with ECM, respectively (p<0.01). The histologic findings of skin biopsy specimens from ECM lesion in 7 cases consisted of perivascular and interstitial infiltrate of lymphocytes, plasma cells...

Seiologic and pathologic studies of 24 cases with erythema chronicum migrans (ECM) were reported. The serum anti-Borrelia burgdorferi(BB) antibody was measured by ELISA in 24 cases with ECM. The Binding Indexes of IgM and IgG anti-BB antibodies were significantl increased in 20(83%)and 11(45%) out of the 24 cases with ECM, respectively (p<0.01). The histologic findings of skin biopsy specimens from ECM lesion in 7 cases consisted of perivascular and interstitial infiltrate of lymphocytes, plasma cells and/or eosinophils, mast cells. These studies showed that the determination of anti-BB antibody is sensitive and specific for diagnosing early Lyme disease.

24例患者均在蜱咬后出现皮肤慢性游走性红斑,其中16例伴淋巴结大、头痛、发热及项强。用ELISA法测定24例患者血清抗BB抗体水平,20例IgM—抗BB抗体阳性;11例IgG—抗BB抗体阳性;两种抗体总阳性率达91.67%。7例皮肤红斑标本病理检查呈急性非特异性渗出性炎症。提示血清抗BB抗体测定是诊断LD的一种敏感和特异的方法。

uantitative determination of anticardiolipin antibodies (ACA) was performedwith a highly specific,sensitive and reproducible ELISA method.Experimental re-sults showed that the percentage of inhibition of cardiolipin binding activity toACA amounts to 90%,Binding index(BI)variation was less than 4% intra-assayand 8% inter-assay.Results were expressed as a BI instead of optical density(OD)for compensation of the variation due to changes of conditions and procedures inthe experiments.The average value(X)...

uantitative determination of anticardiolipin antibodies (ACA) was performedwith a highly specific,sensitive and reproducible ELISA method.Experimental re-sults showed that the percentage of inhibition of cardiolipin binding activity toACA amounts to 90%,Binding index(BI)variation was less than 4% intra-assayand 8% inter-assay.Results were expressed as a BI instead of optical density(OD)for compensation of the variation due to changes of conditions and procedures inthe experiments.The average value(X) of BI plus 2 standard derivation(SD)in144 healthy individuals was defined as the upper limit of normal value.The normalvalue(X+2SD)of IgG-,IgA-and IgM-ACA BI is 2.35、2.06、and 2.5 respectively.Theprevalence of ACA in the patients with SLE and RA(46% and 35%)is higher thanthat of normal individuals(3.5%.P<0.05).In 50 patients with SLE,the ACApositive rate of IgG,IgM,and IgA is 44%,30%,and 22% respectively.This stu-dy confirms that ACA may act as the assistant factor for diagnosis of SLE andRA and the necessarily diagnostic basis of APS.The presence of ACA implicatesthe risk of developing thrombosis clinically.

 本文介绍一种检测ACA的ELISA方法。该法重复性好、特异性强、敏感性高、方法简便,144份正常人血清BI的X+2SD作为正常值上限,其中IgG-ACABI为2.35,IgA-ACA为2.06,IgM-ACA为2.5。SLE和RA患者ACA阳性率(46%和35%)明显高于正常人群(3.5%,P<0.05)。SLE患者中各类ACA检出阳性率为IgG44%,IgM30%、IgA22%。因此,ACA值可作为SLE和RA的辅助诊断指标和抗磷脂综合征的诊断依据;也可作为临床上预测血栓形成趋势的危险标志。

 
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