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slow-release carrier
相关语句
  缓释载体
     Objective Three soluble materials were used as carrier of recombinant human bone morphogenetic protein-2(rhBMP-2) in order to seek suitable slow-release carrier of rhBMP-2,which induced neogenetic cartilage in canine tracheal autografting segment.
     目的 以三种可溶性物质作为重组人骨形态发生蛋白 - 2 (rhBMP - 2 )的载体 ,寻求适合作为rhBMP- 2在犬的自体气管移植段内诱发新生软骨的缓释载体
短句来源
     To investigate the validity of hydroxyapatite bone cement (HAC) as a slow-release carrier of bioactive factor.
     探讨羟磷灰石骨水泥(HAC)作为生物活性因子缓释载体的有效性。
短句来源
     CORAL AS A SLOW-RELEASE CARRIER FOR RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2
     应用珊瑚作为重组人骨形成蛋白-2缓释载体的动物实验研究
短句来源
     As a slow-release carrier of drug and BMP, HAC throw out a good release characteristic.
     这表明 HAC作为药物和 BMP 缓释载体显示出良好的缓释特性。
短句来源
     Selecting high efficiency and low toxicity chrysanthine ester compounds as insecticide and high absorbency Sepiolite as slow-release carrier, the compatibility problem of insecticide and coatings can be solved.
     选用高效低毒的菊酯类化合物为杀虫剂 ,以具有高效吸附性的海泡石为杀虫剂的吸附剂及缓释载体 ,解决了杀虫剂与涂料体系的相容性问题。
短句来源
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  “slow-release carrier”译为未确定词的双语例句
     Experiment study on hydroxyapatite bone cement as a slow-release carrier of bioactive factor
     羟磷灰石骨水泥载体缓释生物活性因子的有效性研究
短句来源
  相似匹配句对
     Slow Food
     美食卫士——意大利“慢餐者”
短句来源
     On "The Slow Nature
     On“The Slow Nature”
短句来源
     On the“slow and gentle” in Taiji-quan
     初论太极拳之“缓慢轻柔”
短句来源
     Review on slow-release fertilizer
     缓释化肥再认识
短句来源
     Development of slow-release fertilizers
     缓释肥料的开发
短句来源
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  slow-release carrier
Characteristics of clay as a slow-release carrier of Zn by direct implantation into tree trunks
      


Objective:To prepare recombinant human morphogenetic protein 2 (rhBMP 2)/coral composite attificial bone and to determine its osteoinductivity.Methods:The composite artificial bone was prepared by combining coral with rhBMP-2,and was implanted into the muscle pouches of mice.Sixty six mices were divited into three groups:Group 1, the composite bone (coral:rhBMP 2(w/w)=20∶1)transplanted;Group 2, the composite bone (coral∶rhBMP 2(w/w)=40∶1);and Group 3 the coral alone.All the animals were killed at intervals...

Objective:To prepare recombinant human morphogenetic protein 2 (rhBMP 2)/coral composite attificial bone and to determine its osteoinductivity.Methods:The composite artificial bone was prepared by combining coral with rhBMP-2,and was implanted into the muscle pouches of mice.Sixty six mices were divited into three groups:Group 1, the composite bone (coral:rhBMP 2(w/w)=20∶1)transplanted;Group 2, the composite bone (coral∶rhBMP 2(w/w)=40∶1);and Group 3 the coral alone.All the animals were killed at intervals of 1,3,5 weeks after operation.The speciments were evaluated by light microscope and image analysis.Results:Cartilage growth in the pores or on the surface of the implants was observed one week after operation, woven bone three weeks and lamellar bone with bone marrow six weeks,partial coral absorption was observed,the amount of induced endochondral bone was time and rhBMP 2 dose dependent.Conclusion:The results indicate that the composite possesses a superior osteoinductivity and coral may act as one of the most suitable rhBMP 2 slow releasing carriers currently available.

目的:制备珊瑚(coral)与重组人骨形成蛋白-2(rhBMP-2)复合人工骨并测试其骨诱导活性。方法:将rhBMP-2与珊瑚复合后植入鼠肌袋内。66只小鼠随机分为3组:第1组为复合骨(1∶20w/w);第2组为复合骨(1∶40w/w);第3组为单独珊瑚。术后1、3、6周处死动物,光镜下观察,并用图象分析法作成骨定量测定,结果:术后1周,可见复合材料表面及孔洞内有软骨形成。3周出现编织骨。6周形成含骨髓的板层骨。珊瑚被部分吸收。诱导成骨的量有时间依赖性和rhBMP-2剂量依赖性。结论:rhBMP-2/coral复合人工骨具有良好的诱导成骨能力;珊瑚可能是目前能使用的rhBMP-2最合适的缓释载体。

By combining coral with recombinant human bone morphogenetic protein-2 (rhBMP-2), rhBMP-2/coral composited artificial bone was obtained; then, the composite was implanted into the muscle pouches of mice, coralused as control. The mice were sacrificed at 1, 3, 6 week respectively after operation and ectopic osteoinductive activity was examined by histology. The results showed that the composite possessed definitive osteoinductivity andinduced endochondral bone formation in the regions of implantation; coral did...

By combining coral with recombinant human bone morphogenetic protein-2 (rhBMP-2), rhBMP-2/coral composited artificial bone was obtained; then, the composite was implanted into the muscle pouches of mice, coralused as control. The mice were sacrificed at 1, 3, 6 week respectively after operation and ectopic osteoinductive activity was examined by histology. The results showed that the composite possessed definitive osteoinductivity andinduced endochondral bone formation in the regions of implantation; coral did not disturb the osteoinductive activity of rhBMP-2 and acted as one of the most suitable rhBMP-2 slow-release carriers currectly available. Thecomposite will be a new type of bone substitute in orthopaedics and maxillofacial surgery.

将大肠杆菌表达的重组人骨形成蛋白-2(rhBMP-2)和珊瑚(coral)复合,制成rhBMP-2/coral复合人工骨,将其植入小鼠股部肌肉内,并以单纯珊瑚植入作对照,术后1、3、6周取材,组织学观察。结果显示:rhBMP-2/coral复合人工骨在植入局部诱导形成骨和软骨,表现出良好的异位诱导成骨能力;珊瑚对rhBMP-2的活性未产生不利影响,是rhBMP-2的良好缓释载体。此复合人工骨可望作为一种新型生物性植骨材料而应用于骨科和颌面外科。

Objective Three soluble materials were used as carrier of recombinant human bone morphogenetic protein-2(rhBMP-2) in order to seek suitable slow-release carrier of rhBMP-2,which induced neogenetic cartilage in canine tracheal autografting segment.Methods 32 mongrel dogs were randomly and equally divided into 4 groups.A five-ring cervical tracheal segment was harvested as the autograft.The materials including dextran,polyvinyl pyrrolidone(PVP) and collagen were respectively combined with equal rhBMP-2...

Objective Three soluble materials were used as carrier of recombinant human bone morphogenetic protein-2(rhBMP-2) in order to seek suitable slow-release carrier of rhBMP-2,which induced neogenetic cartilage in canine tracheal autografting segment.Methods 32 mongrel dogs were randomly and equally divided into 4 groups.A five-ring cervical tracheal segment was harvested as the autograft.The materials including dextran,polyvinyl pyrrolidone(PVP) and collagen were respectively combined with equal rhBMP-2 and then injected into the soft tissues between cartilaginous rings of autografts.In addition,without carrier group was used as controls.Then the autografts were heterotopically transplanted into greater omentum.The animals were sacrificed at postoperative 4 weeks,and the postmortem specimens were examined grossly and histologically.Results Cartilage rings of the grafts were partly absorbed in all four groups.New cartilage was induced in the rhBMP-2 injected area in the groups in which PVP or collagen was used as carrier,and more new cartilage was observed in the collagen group.Conclusions PVP and collagen could be sustained as release carriers for rhBMP-2 in tracheal autograft.Collagen is more effective as a carrier than other vehicles and it could enhance the ability of rhBMP-2 inducing cartilage regeneration in tracheal transplantation.

目的 以三种可溶性物质作为重组人骨形态发生蛋白 - 2 (rhBMP - 2 )的载体 ,寻求适合作为rhBMP- 2在犬的自体气管移植段内诱发新生软骨的缓释载体。方法  32只犬随机等分 4组 ,颈部切取 5环气管段作为移植段。等量的rhBMP - 2分别与葡聚糖、聚乙烯吡咯烷酮 (PVP)和胶原复合 ,另设无载体作为对照 ,均注射入各移植段内。然后将移植段埋入自体的腹腔大网膜中。于术后 4周处死动物取材 ,行大体及组织学观察。结果 移植段固有软骨环被部分地吸收。PVP和胶原组软骨环间rhBMP - 2复合物植入区有大量新生软骨形成 ,且以胶原组更明显。结论 PVP和胶原均可协助rhBMP - 2诱发气管移植段软骨再生 ,胶原更适合充当rhBMP - 2的缓释载体。

 
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