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low-concentration lidocaine
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  低浓度利多卡因
     Effects of low-concentration lidocaine on persistent sodium currents in hypoxic isolated rat CA1 hippocampal neurons
     低浓度利多卡因对大鼠海马CA1区缺氧神经元持续钠电流的影响
短句来源
     Methods In 14 cases of tumescent liposuction using high- dosage,low-concentration lidocaine as local infiltration anesthetic,serum lidocaine concentrations were monitored with automated fluorescence polarization analysis.
     方法对14例大剂量使用低浓度利多卡因作为局麻药的脂肪抽吸术的术中和术后血清利多卡因浓度以免疫荧光测定法进行了动态监测,作出其时间-浓度曲线,并与临床表现相对照。
短句来源
     Objective To investigate the effects of low-concentration lidocaine on the persistent sodium currents enhanced by hypoxia in isolated rat CA1 hippocampal neurons. Methods Brains were harvested from 10-14 day old SD rats of both sexes.
     目的观察低浓度利多卡因对大鼠海马CA1区缺氧神经元持续钠电流的影响,探讨其对缺血脑损伤保护作用的机制。
短句来源
  相似匹配句对
     Low and N.
     Low和N .
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     and for T-N and T-P are quite low.
     对T-N和T-P的去除效果较差。
短句来源
     low cost;
     生产成本低;
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     the concentration of HBeAg was low;
     HBeAg表达量少;
短句来源
     Low-votagize of ZNR
     ZnO压敏陶瓷的低压化
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The authors presented 9 cases of local anesthesia accidents occurred in our and another hospital since 1985. The causes of the accidents included: careless management in 3 cases, error of anesthetic technic in 3 cases, anesthetic overdose in 2 cases,and incorrect injection place in 1 case. The results of the accidents consisted of 1 death and 2 cases dysfunction. The authors considered the systemic side effects were caused by too high concentration of local anesthetic in blood. when the concentration of lidocaine...

The authors presented 9 cases of local anesthesia accidents occurred in our and another hospital since 1985. The causes of the accidents included: careless management in 3 cases, error of anesthetic technic in 3 cases, anesthetic overdose in 2 cases,and incorrect injection place in 1 case. The results of the accidents consisted of 1 death and 2 cases dysfunction. The authors considered the systemic side effects were caused by too high concentration of local anesthetic in blood. when the concentration of lidocaine in blood reached steeply at 50-100μg/ml, thebioche mical transformation of lymphocyite is dose-dependently inhibited. As the local anesthetic concentration rises in blood, the systemic toxic symptoms appear, such as convulsion and death On the contrary, when the low concentration lidocaine of less than 0.1% is administered, no accidents occured even though the total dosage reached 80mg/kg during liposunction under tumescent anaesthesia. As the primary causes of the accidents attribute to careless management, inappropriate administration of local anesthesia and shortage of professional knowledge and experiences, the enhancement of administrative regulations and intensification of medical staffs'trainning on professional knowledge techniques and responsibility are emphasized.

总结自1985年以来,本院及外院手术局麻中医疗过失9例。其中麻醉药品管理不当造成者3例;麻醉技术原因3例;麻醉药过量2例;麻醉药注射部位不当1例。以上原因造成患者死亡1例,功能障碍3个月以上者2例。医疗过失的主要原因是麻醉药品管理不当和医务人员专业知识不牢,技术不熟。加强医院的管理制度,提高医务人员的业务素质,是防范局麻过失的主要措施。对局麻药的全身性不良反应进行了讨论,认为高浓度是造成不良反应的主要因素。当利多卡因血内浓度达50~100μg/ml时,可出现剂量相关性淋巴细胞转化的抑制。血内局麻药的浓度骤然升高,可引起一系列的毒性症状,甚至全身性强直阵挛性惊厥和死亡。

Objective This study was carried out to determine the maximum and safe dosage of li- docaine administered in tumescent liposuction.Methods In 14 cases of tumescent liposuction using high- dosage,low-concentration lidocaine as local infiltration anesthetic,serum lidocaine concentrations were monitored with automated fluorescence polarization analysis.Results The time-concentration curve to- gether with clinical manifestations indicated that in tumescent liposuction,lidocaine,under a concentration...

Objective This study was carried out to determine the maximum and safe dosage of li- docaine administered in tumescent liposuction.Methods In 14 cases of tumescent liposuction using high- dosage,low-concentration lidocaine as local infiltration anesthetic,serum lidocaine concentrations were monitored with automated fluorescence polarization analysis.Results The time-concentration curve to- gether with clinical manifestations indicated that in tumescent liposuction,lidocaine,under a concentration of 0.1 mg/ml mixed with 1/1000000 to 1/2000000 epinephrine,could be administered with a dosage of 35 mg/kg body weight as a local infiltration anesthetic while the serum lidocaine was still within the safety limit and no signs of intoxication manifested.The resulting diminution both in pain and blood loss during the operation enhanced the overall operation safety and suction volume.Conclusion This study provides the basis for high-dosage lidocaine administration in tumescent liposuction.

目的探讨作为局部麻醉剂的利多卡因在肿胀法脂肪抽吸术中的极限剂量是多少,既能达到良好的镇痛效果,又能安全地使用而不产生毒副作用。方法对14例大剂量使用低浓度利多卡因作为局麻药的脂肪抽吸术的术中和术后血清利多卡因浓度以免疫荧光测定法进行了动态监测,作出其时间-浓度曲线,并与临床表现相对照。结果在此类手术中,利多卡因在0.1mg/ml的浓度下,加入1/1百万~1/2百万肾上腺素,其用量可达35mg/kg 体重而血清高峰浓度仍在安全范围内,无中毒症状,既可减轻病人的疼痛,又可减少出血,提高安全性,增加脂肪抽吸量。结论本研究为肿胀法吸脂术中大剂量使用利多卡因的临床实践提供了理论依据。

Objective:To explore a method of liposuction with mildly trauma quickly and completely Method:The concentration of 0 015%~0 03% lidocaine was used incoruse of liposculture with tumescent technique,the tumescented fat was broken by vibrating and then drawn through low attraction To count the quality of bleeding on Hb pre operation and after operation Results:The liposuction of tumescent and vibration by using lower concentration lidocaine...

Objective:To explore a method of liposuction with mildly trauma quickly and completely Method:The concentration of 0 015%~0 03% lidocaine was used incoruse of liposculture with tumescent technique,the tumescented fat was broken by vibrating and then drawn through low attraction To count the quality of bleeding on Hb pre operation and after operation Results:The liposuction of tumescent and vibration by using lower concentration lidocaine is more easily,quickly and mildly

目的 :探讨一种低创、快速、确切的吸脂方法。方法 :将 0 .0 15~ 0 .0 3 %利多卡因肿胀液行皮下快速超量灌注 ,用高频共振吸脂机将充分肿胀的脂肪振碎 ,低负压吸出体外 ,同时计算术中出血量。 结果 :本组 13例术中出血量平均约 14 ml,占抽出物的0 .84%。吸脂快速、彻底 ,术后皮肤表面平滑 ,皮肤松驰度明显改善。 结论 :超低浓度利多卡因皮下超量灌注行指肪共振吸脂是一种操作更简单、更快速、真正低创的吸脂技术

 
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