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exacerbation period
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  加重期
     1. The levels of plasma TXB2, Fbgg , D-dimer and blood PaCO2 were significantly increased (P<0.01), and the levels of plasma 6-keto-PGF1α, PT, APTT, AT-Ⅲ:A and blood PaO2 were significantly decreased (P <0.01)in ozagrel group and control group in exacerbation period compared with healthy subjects, but in ozagrel group and control group showed no difference(P > 0.05).
     1. 两组慢性肺心病急性加重期患者治疗前分别与健康组比较,TXB2、Fbgg、D-dimer和PaCO2 显著高于健康组(P <0.01),6-keto-PGF1α、PT、APTT、AT-Ⅲ:A和PaO2显著低于健康组(P <0.01),此两组间上述指标无差别(P > 0.05)。
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     The level of PaO2 had a negative relation with serum myocardial enzymes(r = -0.67~-0.87,P<0.01) in the COPD patients during acute exacerbation period.
     COPD急性加重期患者PaO2水平与对应的血清心肌酶呈直线负相关(r=-0.67~-0.87,P<0.01)。
短句来源
     Clinical Study of Blood Sugar in Acute Exacerbation Period of Pneumocardial Disease
     肺心病急性加重期血糖的临床研究
短句来源
     METHODS Fifty-six patients with COPD in acute exacerbation period were divided into treatment group and control group.
     方法56例COPD急性加重期患者分为治疗组和对照组。
短句来源
     Efficacy of Sodium Ozagrel in the Treatment of Cor Pulmonale in Exacerbation Period
     奥扎格雷钠对慢性肺心病急性加重期凝血机制的影响及治疗作用的研究
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  “exacerbation period”译为未确定词的双语例句
     Results:The serum T 4、T 3 and FT 3 levels in patients with cor pulmonale were significantly lower during exacerbation period than that in COPD group(P<0.01)and the serum rT 3 level in patients with cor pulmonale was significantly higer(P<0.05). The serum FT 4 and TSH levels had no significant difference between two groups(P>0.05).
     结果 :肺心病组血清T4、T3 、FT3 均明显低于对照组 (P <0 0 1) ,FT4轻度下降 ,但差异无显著性 (P >0 0 5 ) ,rT3 水平明显增高 (P <0 0 5 ) ,TSH水平两组比较差异无显著性 (P >0 0 5 )。
短句来源
     Results The serum T_4,T_3 and FT_3 levels in patients with cor pulmonale were significantly lower during the exacerbation period than that in COPD group(P<0.01). The serum FT4 and TS levels showed no significant difference between the groups(P>0.05).
     结果肺心病组血清T3,T4,FT3均明显低与对照组(P<0.01),FT4轻度下降,但差异无显著性(P>0.05),TSH水平两组比较差异无显著性(P>0.05)。
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     Using flow cytometry assay, Th1/Th2 ratio was estimated by quantification of cytokins (IL-4, r-IFN) inside the plasma of single CD4+ T cells. HBV DNA load in peripheral serum of chronic HBV infectants during and after acute exacerbation period was analyzed by polymerase chain reaction (PCR) assay combined with fluorescent probe (FQ-PCR).
     应用流式细胞仪测定外周血中淋巴细胞胞浆内含白细胞介素-4(IL-4)及干扰素-γ(IFN-γ)的细胞的百分比及比值,采用荧光定量聚合酶链反应技术(FQ-PCR),检测慢性乙型肝炎患者发作时及治疗后外周血清中HBV DNA的载量;
短句来源
     There is increased remarkably (P<0 001) in the counts of CD 3 during the recovery period in comparison with during exacerbation period. The counts of CD 3 during the recovery period is close to normal. However, the counts of CD 4/CD 8, IgG, SIgA during exacerbation period and recovery period, no significant change was found.
     2.慢性肺心病急性发作经综合治疗病情缓解时,外周血中CD3显著高于治疗前(P<0.001),但CD4、CD8、IgG、SIgA及IgE治疗前后无明显统计学差异。
短句来源
     Objective To study the hemodynamic and oxygen dynamic effects and the mechanism of nitric oxide (NO) inhalation therapy in COPD induced chronic cor pulmonale at acute exacerbation period.
     目的观察吸入一氧化氮(NO)对慢性肺心病急性发作期血流动力学和氧动力学影响,并对其产生机理进行探讨。
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  相似匹配句对
     Permian Period
     二迭纪
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     The period of Franklin D.
     富兰克林 D.
短句来源
     Efficacy of Sodium Ozagrel in the Treatment of Cor Pulmonale in Exacerbation Period
     奥扎格雷钠对慢性肺心病急性加重期凝血机制的影响及治疗作用的研究
短句来源
     Clinical Study of Blood Sugar in Acute Exacerbation Period of Pneumocardial Disease
     肺心病急性加重期血糖的临床研究
短句来源
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  exacerbation period
When compared with the liver biopsies obtained about 2 months after the peak of serum transaminase, cytotoxic/suppressor cells were significantly increased in those obtained during the acute exacerbation period.
      
Dysfunction of calcium and natrium pump activities in the acute exacerbation period of chronic cor pulmonale were closely related to NO level.
      


In order to study the immunologic function in the elderly patients with chronic cor pulmonale, the counts of lymphocyte subpopulation CD 3,CD 4,CD 8 and immunoglobulin SlgA,IgG,IgE in peripheral blood were measured in 82 elderly patients and 40 healthy elderly persons. The results showed that there are decreased remarkably in the counts of CD 3,CD 4 and the ratio of CD 4 to CD 8, increased remarkably in the counts of CD 8,IgG, SIgA (P<0 001) In the elderly patients with exacerbation stage chronic...

In order to study the immunologic function in the elderly patients with chronic cor pulmonale, the counts of lymphocyte subpopulation CD 3,CD 4,CD 8 and immunoglobulin SlgA,IgG,IgE in peripheral blood were measured in 82 elderly patients and 40 healthy elderly persons. The results showed that there are decreased remarkably in the counts of CD 3,CD 4 and the ratio of CD 4 to CD 8, increased remarkably in the counts of CD 8,IgG, SIgA (P<0 001) In the elderly patients with exacerbation stage chronic cor pulmonale in comparison with that of control. The lower the level of CD 3, the poorer the patient′s condition. There is increased remarkably (P<0 001) in the counts of CD 3 during the recovery period in comparison with during exacerbation period. The counts of CD 3 during the recovery period is close to normal. However, the counts of CD 4/CD 8, IgG, SIgA during exacerbation period and recovery period, no significant change was found. The results indicated that functional disturbances of immunity existed in the elderly patients with chronic cor pulmonale. To learn status of immunity will be helped not only in predicting the prognosis, but also in guiding the clinical therapy.

为研究老年慢性肺心病病人的免疫功能,应用免疫荧光法及放免法测定了82例慢性肺心病急性加重期住院病人的T淋巴细胞亚群及免疫球蛋白。结果表明:1.慢性肺心病急性加重期患者外周血中CD3、CD4及CD4/CD8比值明显低于正常对照组(P<0.001),CD8及IgG、SIgA均明显高于正常对照组(P<0.001)。有部分患者(17/82例)IgE明显升高。2.慢性肺心病急性发作经综合治疗病情缓解时,外周血中CD3显著高于治疗前(P<0.001),但CD4、CD8、IgG、SIgA及IgE治疗前后无明显统计学差异。提示:慢性肺心病无论在急性加重期还是在缓解期都存在免疫功能紊乱。了解免疫功能的变化有助于推测预后及指导治疗

Objective To study the hemodynamic and oxygen dynamic effects and the mechanism of nitric oxide (NO) inhalation therapy in COPD induced chronic cor pulmonale at acute exacerbation period. Method Right heart catheterization was performed in 11 cases of chronic cor pulmonale. The hemodynamic parameters and plasma endothelium I(ET I) level were examined and recorded before and after inhalation of 40 ppm NO for 20 minutes. The plasma level of NO and lipid peroxide Ca 2+ Mg 2+ ATPase(calcium...

Objective To study the hemodynamic and oxygen dynamic effects and the mechanism of nitric oxide (NO) inhalation therapy in COPD induced chronic cor pulmonale at acute exacerbation period. Method Right heart catheterization was performed in 11 cases of chronic cor pulmonale. The hemodynamic parameters and plasma endothelium I(ET I) level were examined and recorded before and after inhalation of 40 ppm NO for 20 minutes. The plasma level of NO and lipid peroxide Ca 2+ Mg 2+ ATPase(calcium pump) and Na + K + ATPase(natrium pump) activities of RBC membrane in 30 cases of chronic cor pulmonale and 30 healthy controls were determined synchronously. Results After NO therapy, the average pulmonary pressure (PAPM) and pulmonary vascular resistance index (PVRI) were lowered by 16 6% and 25 9% respectively ( P <0.05). Intrapulmonary shunt was lowered by 16.3% ( P <0.05). ET I also lowered and showed a positive correlation with PAPM ( r =0.59, P <0.05). The activities of calcium and natrium pump were lowered when NO level declined, showing a positive correlation with NO concentration and negative correlation with lipid peroxides. Conclusion NO inhalation therapy exerted favorable hemodynamic and oxygen dynamic effects on COPD induced chronic cor pulmonale in its exacerbation period. Suppression of ET Ⅰ release might be one of the important factors for pulmonary vessel relaxation. Dysfunction of calcium and natrium pump activities in the acute exacerbation period of chronic cor pulmonale were closely related to NO level.

目的观察吸入一氧化氮(NO)对慢性肺心病急性发作期血流动力学和氧动力学影响,并对其产生机理进行探讨。方法对11例肺心病急性发作期患者给予鼻面罩吸入NO40ppm20分钟。治疗前后测定其血流动力学参数和血浆内皮素1(ET1)含量。并测定血浆NO含量,红细胞膜Ca2+Mg2+ATP酶(钙泵);Na+K+ATP酶(钠泵)活性及过氧化脂质含量。结果治疗前后肺动脉平均压(PAPM)和肺血管阻力指数分别下降166%及259%(P<005);肺血分流率下降163%(P<005),ET1含量下降并与PAPM呈正相关,慢性肺心病急性发作期NO含量下降,钙泵与钠泵活性降低,与NO含量呈正相关与过氧化脂质呈负相关。结论吸入NO对肺心病急性发作期患者有良好的血流动力学和氧动力学效应,抑制ET1的释放可能是舒张肺血管的重要机理之一。

Objective to evaluate the efficacy and safety of low dose,topical mitomycin C eyedrops (0.01g·L -1 MMC)in patients with severe vernal keratoconjunctivitis(VKC).Methods Twenty eyes of ten consecutive patients with severe VKC refractory to steroid treatment were treated with topical 0.01g·L -1 MMC eyedrops three times daily for 2 weeks.Results There were manifestly improved symptoms in patients with VKC at the end of the first week.There was significant decrease in ropy mucous discharge,photophobia,conjunctival...

Objective to evaluate the efficacy and safety of low dose,topical mitomycin C eyedrops (0.01g·L -1 MMC)in patients with severe vernal keratoconjunctivitis(VKC).Methods Twenty eyes of ten consecutive patients with severe VKC refractory to steroid treatment were treated with topical 0.01g·L -1 MMC eyedrops three times daily for 2 weeks.Results There were manifestly improved symptoms in patients with VKC at the end of the first week.There was significant decrease in ropy mucous discharge,photophobia,conjunctival hyperemia at the end of the second week treatment period.No adverse effects of treatment with MMC were observed.Conclusions Short term,low dose,topical MMC may be considered to be used in the acute exacerbation periods of patients with severe VKC refractory difficult to be managed by conventional treatment.

目的 评价应用低浓度丝裂霉素 C液 (0 .0 1g·L- 1 MMC)局部治疗重症春季角结膜炎 (VKC)患者的疗效与安全性。方法  10例 2 0眼用皮质类固醇难治的重症 VKC局部应用 0 .0 1g· L- 1 MMC液 ,每日 3次滴眼治疗 2周。结果 在治疗第 1周末患者的自觉症状即有好转 ,至第 2周末 ,粘丝状分泌物、怕光和结膜充血均有明显地减轻 ,未见有任何 MMC治疗的副反应发生。结论 对用传统疗法难于控制的重症 VKC急性恶化期 ,可考虑短期应用低浓度 MMC液作局部治疗

 
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