助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   rb gene probe 的翻译结果: 查询用时:0.199秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

rb gene probe
相关语句
  rb基因为探针
     By Southern Blot hybridization, we have tested cancer tissues of nine stomach cancer patients and one cell line BGC-823 with Rb gene probe, finding that the Rb gene of all the tissues and the cell line are abnormal as compared with that of normal human blood tissues.
     我们用Southern印迹杂交法,以Rb基因为探针,检测了九例胃癌患者的癌组织和一个胃癌细胞株,发现它们与正常人血相比Rb基因全部呈现异常。
短句来源
  相似匹配句对
     THE EXPRESSION OF Rb GENE IN RETINOBLASTOMA
     视网膜母细胞瘤Rb基因表达
短句来源
     RB Gene and Tumor Suppression .
     RB基因与肿瘤抑制
短句来源
     The gene of xylanase B from T.
     但编码该酶的基因xynB在大肠杆菌中的表达较困难。
短句来源
     As to the RYR gene.
     长白猪群中,未发现有该基因存在。
短句来源
     these were proved by FISH using probes specific for Rb-1 gene.
     采用JAB Rb-1探针进行的FISH分析证实了显带分析的结果。
短句来源
查询“rb gene probe”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  rb gene probe
The retinoblastoma (Rb) gene probe p123 M1.8 and p68 Rs2.0 were used to study the frequencies of theBamHI andRsaI restriction fragment length polymorphisms (RFLPs) in the Rb gene among the population of Han nationality in Guangdong Province.
      


Rb gene is a cancer suppressor gene. Its product, Rb protein has close relation with the regulation of cell transformation, cell cycle and transcription. A lot of carcinomas such as retionblastoma, brest cancer, small cell lung cancer, prostate cancer, bladder cancer, oesteosacoma, soft tissue sarcoma etc. are related to the deletion or inactivation of Rb gene. Stomach cancer is a very common carcinoma of the gastrointestinal system. Researchers have shown that the development...

Rb gene is a cancer suppressor gene. Its product, Rb protein has close relation with the regulation of cell transformation, cell cycle and transcription. A lot of carcinomas such as retionblastoma, brest cancer, small cell lung cancer, prostate cancer, bladder cancer, oesteosacoma, soft tissue sarcoma etc. are related to the deletion or inactivation of Rb gene. Stomach cancer is a very common carcinoma of the gastrointestinal system. Researchers have shown that the development of stomach cancer is due to the activation of many oncogenes and the inactivation of antioncogenes. By Southern Blot hybridization, we have tested cancer tissues of nine stomach cancer patients and one cell line BGC-823 with Rb gene probe, finding that the Rb gene of all the tissues and the cell line are abnormal as compared with that of normal human blood tissues. Among the cancer tissues of the nine patients, five have partial deletion of Rb gene, three as well as the cell line have complete deletion of Rb gene. This indicates that the loss of Rb gene is the key link of cancer development. We believe that, with the more sensitive method of Polymerase Chain Reaction (PCR), we can test the fallen cells of stomach hoping that it would be helpful to the early diagnosis of stomach cancer. Meanwhile, this experiment provides target cells of gene therapy research of tumors.

Rb基因是一种抗癌基因,其产物Rb蛋白与细胞转化、细胞周期调节及转录调控有密切关系。许多肿瘤如视网膜母细胞瘤、乳腺癌、小细胞肺癌、前列腺癌、膀胱癌、骨肉瘤、软组织肉瘤等,都与Rb基因的失活或缺失有关。胃癌是消化道常见多发肿瘤,研究表明,其发生发展与多种癌基因的活化、抗癌基因的异常有关。我们用Southern印迹杂交法,以Rb基因为探针,检测了九例胃癌患者的癌组织和一个胃癌细胞株,发现它们与正常人血相比Rb基因全部呈现异常。其中5例发生Rb基因部分缺失,3例及人胃腺癌细胞株BGC-823全部缺失。这表明在胃癌发生过程中Rb基因的丢失是一个重要环节。我们相信用更灵敏的多聚酶链式反应(PCR)技术检测胃脱落细胞,对患癌危险性的早期预报会有很大帮助。同对,本实验也对肿瘤的基因治疗研究提供了靶细胞。

Abstract The retinbolastoma (Rb)gene probe p123 M1.8

运用RB基因内探针,研究了广东地区汉族人群中RB基因内BamHI和Rsal限制性片段多态性位点(RFLP)的基因频率和杂合子频率,发现RsaⅠ位点RFLP的杂合子频率在汉族人群中仅为55%,与国外文献报道的差异有显著性意义。对BamHI和RsaⅠ多态性位点连锁情况研究显示,10.5%的RsaI位点纯合子为BamHI位点杂合子,联合运用此两位点RFLP,可以把RB基因连锁分析的有效率提高到65.5%。

The retinoblastoma (Rb) gene probe p123 M 1.8 andP68 Rs2.0 were used to study the frequencies of the.BamHI and Rsal restriction fragment length polymorphisms (RFLPs) in the Rb gene among the population of Han nationality in Guangdong Province.The result showed that the heterozygotic rate of the Rsal locus was only 55.0%. Linkage study of the BamHI and the Rsal RFLPs demonstrated that 10.s% of the Rsal polymorphic loci were heterozygous for the BamHI RFLP.Thus the combined use of...

The retinoblastoma (Rb) gene probe p123 M 1.8 andP68 Rs2.0 were used to study the frequencies of the.BamHI and Rsal restriction fragment length polymorphisms (RFLPs) in the Rb gene among the population of Han nationality in Guangdong Province.The result showed that the heterozygotic rate of the Rsal locus was only 55.0%. Linkage study of the BamHI and the Rsal RFLPs demonstrated that 10.s% of the Rsal polymorphic loci were heterozygous for the BamHI RFLP.Thus the combined use of the two RFLPs can give information for about 65.5% of the population.

魏军,杜传书BamHIANDRsaIRESTRICTIONFRAGMENTLENGTHPOLYMORPHISMSINRETINOBLASTOMAGENEINACHINESEPOPULATION¥WeiJun;DuChuanshu;(Departmen...

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关rb gene probe的内容
在知识搜索中查有关rb gene probe的内容
在数字搜索中查有关rb gene probe的内容
在概念知识元中查有关rb gene probe的内容
在学术趋势中查有关rb gene probe的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社