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fentanyl patch
相关语句
  芬太尼贴剂
     The Clinical Use and Nursing Care of Fentanyl Patch for Pain Relief in Lung Cancer Patients
     芬太尼贴剂治疗肺癌疼痛的临床应用与护理
短句来源
     Objective To study the efficacy and relevant nursing of the use of Fentanyl patch in the management of pain in lung cancer patients .
     目的 探讨芬太尼贴剂在肺癌疼痛患者中的有效性和护理对策。
短句来源
     Methods Forty two patients with moderate or severe cancer pain were treated by Fentanyl patch.
     方法 选取 4 2例伴有中、重度疼痛的肺癌患者 ,使用芬太尼贴剂止痛。
短句来源
  “fentanyl patch”译为未确定词的双语例句
     Safety of transdermal fentanyl patch and its rational use
     芬太尼透皮贴剂的安全性及其合理使用
短句来源
     The ratio of LF vs HF, which is one of HRV frequency indices, was obviously reduced at 24h after transdermal fentanyl patch as compared with that before TFS (P<0.05). TFS significantly reduced plasma ACTH, β-endorphin and insulin levels, but the change in GH was not significant. No respiratory depression was observed.
     贴剂治疗 2 4h后HRV的低频功率 (LF)与高频功率 (HF)之比明显低于治疗前 ,而应激激素促肾上腺皮质激素 (ACTH)、β 内啡肽和胰岛素也明显降低 (P <0 0 1) ,但生长激素波动不明显。
短句来源
     Objective To evaluate the effect of dosage of durogesic ( transdermal fentanyl patch) titrated by morphine patient-controlled intravenous analgesia (PCIA) in the treatment of cancer pain.
     目的评价吗啡静脉自控镇痛(PCIA)行多瑞吉(芬太尼透皮贴剂)剂量快速滴定对癌性疼痛的治疗作用。
短句来源
     Objective:To research the feasibility,efficacy and method of transdermal fentanyl patch(TDF) in the treatment of postoperative pain.
     目的:探讨芬太尼透皮贴剂(TDF)用于术后镇痛的可行性、优越性及具体实施方案.
短句来源
  相似匹配句对
     Safety of transdermal fentanyl patch and its rational use
     芬太尼透皮贴剂的安全性及其合理使用
短句来源
     the others, the patch.
     其余景观组分均为斑块。
短句来源
     TRANSDERMAL FENTANYL
     芬太尼缓释透皮贴剂
短句来源
     Clinical Observation of Fentanyl Transdermal Patch in Treatment of Moderate Cancer Pain
     芬太尼透皮贴剂在中度癌痛治疗中的临床观察
短句来源
     ③Fentanyl group;
     ③芬太尼组;
短句来源
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  fentanyl patch
Pain Recurrence on the Third Day after Application of a Transdermal Fentanyl Patch
      
The autopsy revealed a 25-μg/h (4.2?mg) transdermal fentanyl patch in the stomach.
      
Fatal outcome in a child after ingestion of a transdermal fentanyl patch
      
With the fentanyl patch, for instance, the upper skin layers serve as a depot for the fentanyl.
      
The fentanyl patch is another alternative and should be changed every three days.
      
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OBJECTIVE :To evaluate the efficacy and safety of transdermal fentanyl in treatment of severe cancer pain. METHODS :32 patients were recruited into a randomized,open, twoperiod,crossover study to compare transdermal fentanyl with a sustainedrelease oral morphine and another 38 patients were recruited into an open study.The fentanyl patches were replaced every 72 h and sustainedrelease morphine was administrated every 12 h. RESULTS]:Pain relief was good throughout the study with side effects,such...

OBJECTIVE :To evaluate the efficacy and safety of transdermal fentanyl in treatment of severe cancer pain. METHODS :32 patients were recruited into a randomized,open, twoperiod,crossover study to compare transdermal fentanyl with a sustainedrelease oral morphine and another 38 patients were recruited into an open study.The fentanyl patches were replaced every 72 h and sustainedrelease morphine was administrated every 12 h. RESULTS]:Pain relief was good throughout the study with side effects,such as dizziness and nausea,similar to that of sustainedrelease morphine.

目的:观察芬太尼透皮贴剂(多瑞吉)对晚期癌症伴重度疼痛患者的镇痛效果及其不良反应。方法:采用多中心随机自身对照及开放试验设计,对照药选用缓释吗啡片,二种药物均采用滴定法给药原则,至24h无疼痛或基本不痛为止。多瑞吉q72h一贴,缓释吗啡q12h一次。评价指标为疼痛强度、疼痛缓解率、生活质量等。结果:多瑞吉可使患者的疼痛强度降低到3.0以下,中度疼痛缓解率达到100%,生活质量明显改善。与对照组相比,不良反应略低,但无显著性差异。结论:多瑞吉可有效地控制上述疼痛,不良反应较低,患者接受程度好。

Objective To evaluate the pain control, general condition and well-being of the patients with advanced cancer treated with transdermal fentanyl as well as the effects of transdermal fentanyl on heart rate variability (HRV) and endocrine function. Methods This open prospective study included 40 patients with advanced cancer. The direct conversion ratio from oral morphine to transdermal fentanyl system (TFS) was 100:1 daily. In patients who had never received any opioid before the initial dose of TFS was 25μg/h....

Objective To evaluate the pain control, general condition and well-being of the patients with advanced cancer treated with transdermal fentanyl as well as the effects of transdermal fentanyl on heart rate variability (HRV) and endocrine function. Methods This open prospective study included 40 patients with advanced cancer. The direct conversion ratio from oral morphine to transdermal fentanyl system (TFS) was 100:1 daily. In patients who had never received any opioid before the initial dose of TFS was 25μg/h. The transdermal system was changed every 72h and the dosage was adjusted to the need of the patients according to the VAS scores and the requirement of morphine. 8 hospitalized patients were monitored by 24h Holter for changes in HRV. Blood samples were taken before transdermal fentanyl patch when pain was severe and 24h after TFS for determination of ACTH,β-endorphin, growth hormone(GH) and insulin levels.Results Pain relief during treatment with transdermal fentanyl was significant accoring to VAS scores. Well-being scores showed that patients' quality of life including appetite, sleep, mental state and daily activities was significantly improved after two weeks treatment. The ratio of LF vs HF, which is one of HRV frequency indices, was obviously reduced at 24h after transdermal fentanyl patch as compared with that before TFS (P<0.05). TFS significantly reduced plasma ACTH, β-endorphin and insulin levels, but the change in GH was not significant. No respiratory depression was observed. The incidences of constipation, nausea and vomiting and skin pruritus did not markedly changed following long-term TFS.Conclusions Transdermal fentanyl provides an effective , safe treatment modality in patients with cancer pain with low side effects.

目的 评价芬太尼贴剂的镇痛效果 ,和对心率变异性 (HRV)及机体应激状态的影响。方法 本研究为前瞻、开放试验。 40例晚期癌痛患者作为研究对象 ,试验前口服吗啡的患者按 10 0 :1的比例转换为芬太尼贴剂 ;未用过阿片类药物者 ,初始芬太尼剂量为 2 5 μg/h贴剂。透皮系统每 72h更换一次 ,剂量根据患者疼痛自我评分 (VAS)和对注射吗啡的需要量调整。结果 芬太尼贴剂治疗期间患者疼痛明显缓解 ,VAS评分与治疗前相比明显降低 (P <0 0 1)。治疗 2周时 ,问卷调查显示患者的睡眠、精神状态以及日常生活较治疗前明显改善。贴剂治疗 2 4h后HRV的低频功率 (LF)与高频功率 (HF)之比明显低于治疗前 ,而应激激素促肾上腺皮质激素 (ACTH)、β 内啡肽和胰岛素也明显降低 (P <0 0 1) ,但生长激素波动不明显。无一例发生呼吸抑制 ,便秘、恶心呕吐及皮肤瘙痒发生率 ,用药前后均无显著性变化。结论 芬太尼贴剂用于治疗晚期癌痛有效、安全、副作用小 ,其良好的镇痛效果对机体的应激反应和植物神经功能平衡均产生有益影响

Objective:To expend the application of fentanyl transdermal system and accu-mulate more clinical experience.Methods:Advanced cancer patients with medium or severe chronic pain were recruited into an open crossover study controlled by sustained-release morphine and an open study.Pain intensity and pain relief were chosen to evaluate the efficacy.Dose adjustment and period of treatment were also recorded.Results:One hundred and sixty-nine patients participated in and finished the controlled study.Another772patients...

Objective:To expend the application of fentanyl transdermal system and accu-mulate more clinical experience.Methods:Advanced cancer patients with medium or severe chronic pain were recruited into an open crossover study controlled by sustained-release morphine and an open study.Pain intensity and pain relief were chosen to evaluate the efficacy.Dose adjustment and period of treatment were also recorded.Results:One hundred and sixty-nine patients participated in and finished the controlled study.Another772patients participated in the open study.Among them,7patients dropped out because of adverse drug events including drowsiness,delirium,dysphoria,topical skin allergy,dizziness,respiratory depression and severe phlegm.It showed that most patients could obtain good pain control with both transdermal fen-tanyl and sustained-release morphine.A fentanyl patch of25or50ug /h was enough to relieve medium to severe pain for3days.The average period of treatment was38days with9days as the minimum and159days as the maximum.It also had the trend that the dosage increased with time (P<0.01),but it had little clinical meaning.Main adverse drug events were nausea,dizziness and constipation with lower incidence than morphine.From the open study it was found that life quality was significantly improved after the treatment.Conclusion:This time we reas-sure the efficacy and safety of transdermal fentanyl in large scale and with longer period of treat-ment.This novel route of fentanyl administration may provide a convenient treatment for out-pa-tients and aid compliance.

进一步验证芬太尼透皮贴剂用于癌痛的疗效、不良反应,并为临床用药提供参考。方法:采用多中心自身对照和无对照开放试验设计,对照药选用缓释吗啡,疗效评价标准为疼痛强度,疼痛缓解度。观察用药过程中出现的不良反应及剂量与疗程的关系。结果:共完成941例,其中自身对照试验169例,开放试验772例,开放试验组有7例因不良反应退出试验。结果显示经过剂量调整,芬太尼透皮贴剂可较好地缓解中度以上疼痛。主要不良反应为恶心、头晕、便秘等,临床表现与吗啡类似,发生率比吗啡低。随用药时间增加,芬太尼透皮贴剂的剂量有所增加,但大部分患者的用药剂量在25~50μg/h。结论:芬太尼透皮贴剂用于癌痛具有与吗啡类似的疗效、不良反应小。我国患者每3日使用剂量多为25μg/h或50μg/h。

 
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