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aromatasecy p
相关语句
  芳香化酶p450
     The expression and meaning of aromatasecy P450 in the tissue of endometrial hyperplasia and cancer
     芳香化酶P450在子宫内膜增殖及癌变组织中的表达及意义
短句来源
     The Expression and Meaning of Aromatasecy P450 in the Tissue of Endometrial Hyperplasia and Cancer
     芳香化酶P450在子宫内膜增殖症及癌变组织中的表达及意义
短句来源
     Methods The immunohistochemiscal S-P method techniques were amplified to study the expression of aromatasecy P450,estrogen receptor(ER)and progesterone receptor(PR)in the tissues of endometrial from the observed group of 116 cases,including 30 cases of simple endometrial hyperplasia,32 cases of complex endometrial hyperplasia and 54 cases of endometrial atypical hyperplasia and analysed the clinical processement of these cases.
     方法应用免疫组织化学SP法对子宫内膜单纯性增殖30例、复杂性增殖32例及非典型增殖54例中的芳香化酶P450、雌激素受体(ER)及孕激素受体(PR)的表达进行检测,并结合临床过程进行分析。
短句来源
     Results There was no the positive expression in the normal endometrial tissues. But the positive expressions of aromatasecy P450 were found in the tissues of endometrial hyperplasia(simple endometrial hyperplasia,complex endometrial hyperplasia and atypical hyperplasia). The rates of the positive expressions were 41.1%,46.1% and 73.2% respectively.
     结果在正常增生期子宫内膜组织中无芳香化酶P450的表达,子宫内膜增殖(单纯性增殖、复杂性增殖、非典型增殖)组织中芳香化酶P450呈阳性表达,阳性表达率分别为41.1%、46.1%、73.2%,阳性表达率差异有统计学意义(χ2=46.69,P<0.01);
短句来源
     Objective To study the value of aromatasecy P450 in the tissues of endometrial hyperplasia and atypical hyperplasia in clinical diagnosis and treatment.
     目的探讨芳香化酶P450在子宫内膜增殖和非典型增殖中的诊断和治疗价值。
短句来源
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  “aromatasecy p 450”译为未确定词的双语例句
     The correlations of the expressions of aromatasecy P450, ER and PR in endometrial hyperplasia and carcinomatous changes tissue. have not been shown in this study.
     本研究未显示芳香化酶P45O、ER及PR在子宫内膜增殖组织中阳性表达有相关性。
短句来源
  相似匹配句对
     The Expression and Meaning of Aromatasecy P450 in the Tissue of Endometrial Hyperplasia and Cancer
     芳香化酶P450在子宫内膜增殖症及癌变组织中的表达及意义
短句来源
     The expression and meaning of aromatasecy P450 in the tissue of endometrial hyperplasia and cancer
     芳香化酶P450在子宫内膜增殖及癌变组织中的表达及意义
短句来源
     P450 and Cyt.
     P450、Cyt.
短句来源
     Aromatasecy p450 expression and clinical application in the tissues of endometrial hyperplasia and atypical hyperplasia
     芳香化酶P450在子宫内膜增殖及非典型增殖组织中的表达
短句来源
     Identification of cytochrome P450
     氟西汀氧化代谢酶的鉴定及临床个体化给药剂量
短句来源
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Objective To investigate the expression of aromatasecy P450 in the tissues of endometrial hyper-plasia,atypical hyperplasia and carcinomatous changes. Methods The immunohistochemical S-P method techniques were amplified to explore the expression of aromatasecy P450 in the tissues of endometrium.One hundred and forty-eight cases were chosed as observed groups.Thirty-seven cases of the normal prolificative phase endometria were chosed as control group. Results There was not significient positive...

Objective To investigate the expression of aromatasecy P450 in the tissues of endometrial hyper-plasia,atypical hyperplasia and carcinomatous changes. Methods The immunohistochemical S-P method techniques were amplified to explore the expression of aromatasecy P450 in the tissues of endometrium.One hundred and forty-eight cases were chosed as observed groups.Thirty-seven cases of the normal prolificative phase endometria were chosed as control group. Results There was not significient positive expression in the control group.But the positive expressions were found in observed groups.The rates of the positive expressions were 45%,72% and 75% respectively.There were significant difference among four groups.There was no significant difference between atypical hyperplasia and carcinomatous changes.But there was difference in positive cell numbers between the two groups. Conclusion There were correlations between the abnormal expression rates of aromatasecy P450 and the occurrence,development and the degree of the histological atypia in endometrial atypical hyperplasia.Aromatasecy P450 may be a factor that can induce endometrial hyperplasia and carcinomatous changes.It may become a biomarker of early carcinomatous changes in endometrial tissues.

目的探讨芳香化酶P450在子宫内膜增殖、非典型增殖及癌变组织中的表达。方法应用免疫组织化学SP法对子宫内膜增殖、非典型增殖及癌变子宫内膜(观察组)148例芳香化酶P450的表达进行研究,并设正常增殖期子宫内膜37名为对照组。结果对照组无芳香化酶P450表达,观察组芳香化酶P450呈阳性表达,表达率分别为45%、72%、75%,两组差异有统计学意义;非典型组与癌变组阳性表达率差异无统计学意义,但表达的阳性细胞数差异有统计学意义。结论芳香化酶P450的异常表达与子宫内膜增殖癌变的发生、发展有关,组织学异型性与阳性表达率增高有关;提示芳香化酶P450可能是促使子宫内膜细胞增殖及恶变的促进因素之一。

Objective To study the value of aromatasecy P450 in the tissues of endometrial hyperplasia and atypical hyperplasia in clinical diagnosis and treatment.Methods The immunohistochemiscal S-P method techniques were amplified to study the expression of aromatasecy P450,estrogen receptor(ER)and progesterone receptor(PR)in the tissues of endometrial from the observed group of 116 cases,including 30 cases of simple endometrial hyperplasia,32 cases of complex endometrial hyperplasia and 54 cases of...

Objective To study the value of aromatasecy P450 in the tissues of endometrial hyperplasia and atypical hyperplasia in clinical diagnosis and treatment.Methods The immunohistochemiscal S-P method techniques were amplified to study the expression of aromatasecy P450,estrogen receptor(ER)and progesterone receptor(PR)in the tissues of endometrial from the observed group of 116 cases,including 30 cases of simple endometrial hyperplasia,32 cases of complex endometrial hyperplasia and 54 cases of endometrial atypical hyperplasia and analysed the clinical processement of these cases.Results There was no the positive expression in the normal endometrial tissues.But the positive expressions of aromatasecy P450 were found in the tissues of endometrial hyperplasia(simple endometrial hyperplasia,complex endometrial hyperplasia and atypical hyperplasia).The rates of the positive expressions were 41.1%,46.1% and 73.2% respectively.There were significant relationships among fouth groups(χ2=46.69,P<0.01).There were no relationship between the rates of the positive expressions of ER and PR and degree of the histological atypia.There were no relationship between the expressions rates of aromatasecy P450 and the expressions of ER and PR in endometrial hyperplasia(simple endometrial hyperplasia,complex endometrial hyperplasia and atypical hyperplasia.).Conclusion Aromatasecy P450 may be a factor that induces endometrial hyperplasia and carcinomatous changes.And it may become a biological marker in early carcinomatous changes in endometrial tissues.It indicates that the occurrence of endometrial hyperplasia had a relationship with estrogen stimulation in endometrium.The positive expressions of PR may be a prognostic factor in conservative treatmeat of endometrial hyperplasia.

目的探讨芳香化酶P450在子宫内膜增殖和非典型增殖中的诊断和治疗价值。方法应用免疫组织化学SP法对子宫内膜单纯性增殖30例、复杂性增殖32例及非典型增殖54例中的芳香化酶P450、雌激素受体(ER)及孕激素受体(PR)的表达进行检测,并结合临床过程进行分析。结果在正常增生期子宫内膜组织中无芳香化酶P450的表达,子宫内膜增殖(单纯性增殖、复杂性增殖、非典型增殖)组织中芳香化酶P450呈阳性表达,阳性表达率分别为41.1%、46.1%、73.2%,阳性表达率差异有统计学意义(χ2=46.69,P<0.01);ER及PR的表达与子宫内膜组织细胞的异型性程度无关;芳香化酶P450与ER、PR在子宫内膜增殖组织中(单纯性增殖、复杂性增殖、非典型增殖)的表达不存在相关性。结论芳香化酶P450可能是子宫内膜细胞增殖及恶变的促进因素之一,并可能成为子宫内膜早期癌变的生物学标记物。ER的阳性表达说明子宫内膜增殖的发生与子宫内膜局部雌激素的刺激作用有关。PR的阳性表达可以作为子宫内膜增殖保守治疗中估计预后的有效指标。

 
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