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effect of vaccine
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  疫苗效果
     Objective Using the methods of RT-PCR and virus isolation for verifying the SARS infection animal model and evaluating the effect of vaccine.
     目的 通过RT PCR及病毒分离等方法 ,鉴定SARS感染性动物模型是否成立 ,并对疫苗效果进行评估。
短句来源
     Methods Descriptive epidemiology was used to analyze the three dimensional distribution of hepatitis and the effect of vaccine.
     方法 采用描述流行病学方法,对肝炎分型三间分布、疫苗效果等进行比较分析。
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  “effect of vaccine”译为未确定词的双语例句
     Cloning and Expression of Porcine Interleukin 4 Gene and Effect of Vaccine Adjuvant
     猪白细胞介素4基因克隆、表达及佐剂效应的研究
短句来源
     Preventive effect of vaccine strain recommended by WHO in 2004 will be superior to the vaccine strain recommended by WHO in 2003.
     2003年WHO推荐使用的流感疫苗株对我省甲3型流感的预防效果不够理想,2004年推荐使用的疫苗株对我省甲3型流感的预防效果较好。
短句来源
     Challenge the mice with a lethal dosage (40LD 50) of influenza virus A /P R/8/34(H1N1) one week after the second dose of vaccine (booster) was given,obser ve the change of body weights and evaluate the protective effect of vaccine.
     加强免疫后 1周 ,用致死性 (40LD50 )流感病毒A PR 8 34(H1N1)攻击小鼠 ,观察小鼠的体重变化和保护作用。
短句来源
     Objective To observe the effect of vaccine injection on serum and urinary soluble interleukin 2 receptor (sIL 2R) in children with simple nephrotic syndrome (SNS).
     目的 观察卡介苗素注射液对单纯性肾病综合征 (SNS)患儿血、尿sIL 2R的影响。
短句来源
     Effect of vaccine injection on serum and urinary sIL-2R in children with simple nephrotic syndrome
     卡介苗素对单纯性肾病综合征患儿血、尿sIL-2R水平的影响
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  effect of vaccine
Thus, no significant effect of vaccine on carriage was detected in this relatively small study.
      
This paper also calls for the diagnosis and reporting of the effect of vaccine-preventable diseases in CF patients at any age.
      
Table 2 shows the effect of vaccine on daily gain, weight after weaning, post weaning weight and finishing weight.
      
Suarez, Effect of vaccine use in the evolution of Mexican lineage H5N2 avian influenza virus.
      
Future work will involve analysing the effect of vaccine-induced anticathepsin L antibodies on down-regulation of CD4 levels on sheep T cells.
      


Serological HBV markers were detected in 276 cases of HBV carrier mothers and their infants. Positive rate of HBeAg and PHSA-R were 48.9% and 52.9% respectively. Positive rate of HBsAg in umbilical cord blood was 9.8% ( 27/276 ). We injected HBV vaccine to 276 infants born from mothers with HBV infection with dosage of 10 HBsAg protion at 0、1、3、6 month of age respectively. The positive rate of HBsAb was 86.8% at 9 month of age in which 51.9% in 27 infants with HBsAg positive respectively. At 24 month of age...

Serological HBV markers were detected in 276 cases of HBV carrier mothers and their infants. Positive rate of HBeAg and PHSA-R were 48.9% and 52.9% respectively. Positive rate of HBsAg in umbilical cord blood was 9.8% ( 27/276 ). We injected HBV vaccine to 276 infants born from mothers with HBV infection with dosage of 10 HBsAg protion at 0、1、3、6 month of age respectively. The positive rate of HBsAb was 86.8% at 9 month of age in which 51.9% in 27 infants with HBsAg positive respectively. At 24 month of age positive rate of HBsAb was 91.4%. Those results were similar with reported effects of immunization program with both HBV vaccine and HBIG. In addition, HBV-DNA and PHSA-R was not detected in all HBs Ab positive infants. Positive rate of Anti-HBs in 21 cases with HBsAg positive in umbilical cord blood was 51.9%. HBsAg was constants in 9 cases. HBV markers of mother and sex of infant did not significance on effect of vaccine immunization. The result indicates that using HBV Vaccine only are the good method.

本文对276例HBsAg阳性母亲及其新生儿血清进行HBV标志检测。母血HBeAg和PHSA-R阳性率分别为48.9%和52.9%。婴儿脐血HBsAg阳性率9.8%(27/276)。对276例新生儿按0、1、3、6月程序,每次肌肉注射乙肝疫苗10μg进行阻断研究。生后9月龄,脐血HBsAg阴性组212例抗-HBs阳转率86.8%,随访24月龄时抗-HBs阳性率91.4%。脐血HBsAg阳性组27例抗HBs阳转率51.9%,9例HBsAg持续阳性。母血HBV标志和婴儿性别对疫苗阻断效果无明显影响。抗-HBs阳转组婴儿血清PHSA-R和HBV-DNA检测均阴性。表明单独使用乙肝疫苗阻断乙肝病毒母婴传播可取得满意效果。

Weaned rabbits were fed with the Microbial Feed Additive(MFA)of Bacillus licheniformis in average diet for 40 days.Investigations on the MFA did influence humoral immunity when vaccine of rabbit haemorrheagic disease was vaccinated without adjuvant.The results showed that Bacillus-Fed treatment had higher hemoagglutination inhibition and serum immunoglabulin levels than non-Bacillus-Fed control.The findings suggested that Fed-bacillus licheniformis had an increasing of humoral immunity and the effect of vaccine...

Weaned rabbits were fed with the Microbial Feed Additive(MFA)of Bacillus licheniformis in average diet for 40 days.Investigations on the MFA did influence humoral immunity when vaccine of rabbit haemorrheagic disease was vaccinated without adjuvant.The results showed that Bacillus-Fed treatment had higher hemoagglutination inhibition and serum immunoglabulin levels than non-Bacillus-Fed control.The findings suggested that Fed-bacillus licheniformis had an increasing of humoral immunity and the effect of vaccine vaccinated with Bacillus licheniformis was better than only vaccine.

本研究采用地衣芽孢杆菌制成微生态制剂,饲喂断奶后的家兔40天,再用兔病毒性出血病(RHD)组织灭活疫苗免疫,检测家兔产生的血清抗体对RHD病毒的特异性血凝抑制价和血清免疫球蛋白的含量。结果,试验组家兔的血清抗体对RHD病毒的特异性血凝抗体和血清免疫球蛋白含量均明显高于对照组。表明,地衣芽孢杆菌对家兔的体液免疫功能有促进作用,RHD组织灭活疫苗与地衣芽孢杆菌制剂相结合较单独使用疫苗的效果更佳

The trial fields observation on epidemiological efficacy of three kinds of inactivated vaccines against HFRS(type Ⅰ vaccines purified from tissue culture of Mogolian gerbils bidney;type Ⅰ vaccines purifid from tissue cluture of mouse brains;type Ⅱ vaccines prepared from tissue culture of hamster kidney)was carried out in the periods of eighth five and ninth five years national medical scientific studies,also the immunological strategy of these vaccines was suggested. The fields...

The trial fields observation on epidemiological efficacy of three kinds of inactivated vaccines against HFRS(type Ⅰ vaccines purified from tissue culture of Mogolian gerbils bidney;type Ⅰ vaccines purifid from tissue cluture of mouse brains;type Ⅱ vaccines prepared from tissue culture of hamster kidney)was carried out in the periods of eighth five and ninth five years national medical scientific studies,also the immunological strategy of these vaccines was suggested. The fields following up and expriment testing was cooperated when vaccine groups and control groups were allocated with cluser sampling.Four kinds of antibody testing methods of IFAT,MCPENT,ELISA and HI were operated for evaluating vaccines antibody reaction. Abstract The three kinds of vaccines were all safe and the moderate and svere side effects of vaccines were 0 56%,1 57%,3 26% for Mongolian gerbils kidney vaccine,mouse brains vaccine,hamster kidney vaccine respectively.The antibody depdendent enhancement did not found in 143581 persons received vaccines aftver four years,also there were on statistically differences in clinical manifestations between 17 HFRS cases in vaccine group and 362 HFRS cases in control group (P>0 10).The 119 inoculated individuals didn′t show any clinical symptom while had seroconversion or increase of IFAT antibody titer which could be defined as second infection.The MCPENT and IFAT antibody reactions of three kinds of vaccine were good after 14 days,one year,two years,three years,four years of vaccine received.The seroconversion rates of MCPENT were 57 81% and 70 71%,51 09% and 61 90%,82 46% and 80 13% for Mongolian gerbils kidney vaccine,mouse brains vaccine,hamster kidney vaccine after 14 days of three doses of injection and one year reinforced respectively.The seroconversion rates of IFAT were 93 69% and 89 04%,84 27% and 83 05%,65 73% and 85 00% Mongolian gerbils kidney vaccine,mouse brains vaccine,hamster kidney vaccine after 14 days of three doses of injection and one year reinforced respectively.The change phenomenon of IFAT and MCPENT antibody was similar.The protection rates in trial fields were 93 77%,94 30%,97 61% for Mongoian gerbils kidney vaccine,mouse brains vaccine,hamster kidney vaccine respectively in the four years of three doses,so these vaccines were good epidemiological efficacy.The immunological strategy of these vaccines showed type Ⅱ vaccine and type Ⅰ vaccine against HFRS could be used in the mixed and type Ⅰ endemic areas,in the mixed of main type Ⅰ endemic areas respectively.These vaccines can protect HFRS clinical infection effectively in four years of trial fields followed up. The study showed the side effects was slight and epidemiological efficacy was satisfied about three kinds of inactivated vaccines against HFRS produced in China when people were received these vaccines in the high endemic area,so the vaccine could be common inoculated.The immunological strategy was suggested according to these research results and epidemiological character of HFRS incidence.

“八五”、“九五”期间连续观察肾综合征出血热(HFRS)沙鼠肾细胞Ⅰ型灭活疫苗(简称:沙鼠苗)、乳鼠脑纯化Ⅰ型灭活疫苗(简称:鼠脑苗)和地鼠肾细胞Ⅱ型灭活疫苗(简称:地鼠苗)在HFRS疫区试验人群中的安全性、血清学和预防效果,并提出免疫策略建议。采取现场与实验室结合的方法。现场试验人群采用整群随机分组,分为疫苗接种组和对照组。实验室血清抗体检测采用间接免疫荧光法(IFAT)、微量细胞病变中和试验(MCPENT)、酶联免疫吸附试验(ELISA)和血凝抑制试验(HI)。研究结果表明3种疫苗安全性良好。在接种人群中的中强反应率较低:沙鼠苗为056%,地鼠苗157%,鼠脑苗326%。在接种疫苗的143,581人中,4年内临床上未出现免疫(感染)增强反应的病例。接种组17例病人与对照组362例病人比较,临床类型差异无显著性(P>01)。119例疫苗接种者,以IFAT证实,再次自然感染汉坦病毒(HV)后,未出现临床症状。3种疫苗血清学效果较好。从3种疫苗全程基础免疫后14天、1年(和加强免疫后14天)、2年、3年4年时,中和抗体和荧光抗体的抽样检出情况看,在基础免疫后14天和相隔1年加强免疫后14天,中和抗体平?

 
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