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faulty prognosis
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  不良预后
     Conclusion: The high expression of VEGF and high MVD correlate significantly with lymph node metastasis and faulty prognosis in patients of NPC.
     结论 :鼻咽癌内VEGF的高表达及高MVD与患者的不良预后及淋巴结转移有关
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     Conclusion:The positive rate of the VEGF and protein receptors of the thyroid tumor rises clearly and the VEGF and protein receptors is the faulty prognosis.
     结论甲状腺癌组织中VEGF及其受体蛋白表达阳性率明显增高,VEGF及其受体蛋白表达为甲状腺癌患者的不良预后
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Objective: To study the expression of vascular endothelial growth factor (VEGF), and the pathological significance of microvascular density (MVD) in nasopharyngeal carcinoma (NPC). Methods: S-P method of immunohistochemistry was adopted to check the expression of VEGF protein and MVD in 64 cases of NPC. Results: The positive rates of VEGF in NPC was 83%. Both VEGF and MVD were correlated significantly with lymph node metastasis and 5-year survival rate (P<0.05). In addition, there was a close positive correlation...

Objective: To study the expression of vascular endothelial growth factor (VEGF), and the pathological significance of microvascular density (MVD) in nasopharyngeal carcinoma (NPC). Methods: S-P method of immunohistochemistry was adopted to check the expression of VEGF protein and MVD in 64 cases of NPC. Results: The positive rates of VEGF in NPC was 83%. Both VEGF and MVD were correlated significantly with lymph node metastasis and 5-year survival rate (P<0.05). In addition, there was a close positive correlation between VEGF and MVD (P<0.01). Conclusion: The high expression of VEGF and high MVD correlate significantly with lymph node metastasis and faulty prognosis in patients of NPC.

目的 :探讨鼻咽癌内血管内皮生长因子 (VEGF)的表达及微血管密度 (MVD)的病理意义。方法 :应用免疫组织化学S P法对鼻咽癌内VEGF的表达及MVD进行检测。结果 :鼻咽癌内VEGF的阳性表达率为 83%(5 3/ 6 4 ) ,VEGF的表达及MVD均与患者的 5年生存率及淋巴结转移相关 (P <0 0 5 ) ,同时VEGF的表达与MVD呈正相关关系 (P <0 0 1)。结论 :鼻咽癌内VEGF的高表达及高MVD与患者的不良预后及淋巴结转移有关

Objective:To explore the relationship between the vascular endothelial growth factor and its receptors in thyroid tumors and to analyse the clinical pathologic significancy.Methods:Using the immunohistology to determine the VEGF and receptors on the basis of 50 cases thyroid carcinoma, 30 case thyroid tumor and 20 cases normal thyroid tissue. Results:(1)The positive rate of the VEGF and its receptors of thyroid carcinoma was clearly higher than that of the thyroid glandoma and the normal thyroid tissue (P<0.01).(2)The...

Objective:To explore the relationship between the vascular endothelial growth factor and its receptors in thyroid tumors and to analyse the clinical pathologic significancy.Methods:Using the immunohistology to determine the VEGF and receptors on the basis of 50 cases thyroid carcinoma, 30 case thyroid tumor and 20 cases normal thyroid tissue. Results:(1)The positive rate of the VEGF and its receptors of thyroid carcinoma was clearly higher than that of the thyroid glandoma and the normal thyroid tissue (P<0.01).(2)The VEGF and protein receptor had no significant difference in the different carcinoma type of tissues(P>0.05).(3)The positive rate of the lymphatic metastasis group of the VEGF and receptors of the thyroid carcinoma was higher than that of non-metastasis thyroid tumor(P<0.01).(4)The positive rate of the prognosis mala group of the VEGF and receptors of the thyroid tumor was higher than that of the prognosis bona group (Pfaulty prognosis.

目的探讨甲状腺肿瘤组织中血管内皮生长因子及其受体表达与临床病理的关系。方法对50例甲状腺癌、30例甲状腺腺瘤、20例正常甲状腺组织采用免疫组织化学方法测定其VEGF及其受体蛋白表达,并分析与临床病理的关系。结果(1)甲状腺癌组织中VEGF及其受体蛋白表达阳性率明显高于甲状腺腺瘤及正常甲状腺组织,均有显著性差异(P<0.01);(2)VEGF及其受体蛋白在甲状腺癌不同组织学类型的表达无显著性差异(P>0.05);(3)甲状腺癌淋巴结转移组VEGF及其受体蛋白表达阳性率明显高于无淋巴结转移组,有显著性差异(P<0.01);(4)甲状腺癌预后不良组VEGF及其受体蛋白表达阳性率明显高于预后良好组,有显著性差异(P<0.01)。结论甲状腺癌组织中VEGF及其受体蛋白表达阳性率明显增高,VEGF及其受体蛋白表达为甲状腺癌患者的不良预后。

 
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