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pregnancy rats
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  孕大鼠
     High Intensity Focused Ultrasound depresses the expressions of leukemia inhibitory factor and Matrix Metalloproteinase-9 in deciduas of early pregnancy rats
     高强度聚焦超声对早孕大鼠蜕膜组织中白血病抑制因子、基质金属蛋白酶-9表达的影响
短句来源
     Objective:To investigate the effect of decoction of Fructus Mume (DFM) on the myoelectric activity of uterine smooth muscle of unpregnancy and early pregnancy rats and study its action mechanism.
     目的 :观察乌梅水煎液对未孕和早孕大鼠子宫平滑肌电活动的影响及研究其作用机理。
短句来源
     Conclusions: The DFM enhances the myoelectricity activity of uterine smooth muscle of unpregnancy and early pregnancy rats which may result from enhacing the start cells electric activity and speeding up the action potential depolarization.
     结论 :乌梅可明显增强未孕和早孕大鼠的子宫肌电活动 ,可能是通过增强了平滑肌起步细胞的电活动并使其动作电位去极化的速度加快所致。
短句来源
     Study on Effects of Fructus Mume on Myoelectric Activity of Uterine Smooth Muscle of Unpregnancy and Early pregnancy Rats and Its Action Mechanism
     乌梅对未孕和早孕大鼠子宫平滑肌电活动的影响及其机理探讨
短句来源
     Methods At different terms of pregnancy,pregnancy rats were exposed to different doses of Diphacine\|Na by oral administration,effects of Diphacine\|Na on pregnancy in the female rats were investigated.
     方法 在孕大鼠着床期、早孕和中孕期经口 1次性灌胃不同剂量的敌鼠钠 ,然后观察敌鼠钠对孕鼠的胚胎毒性。
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  “pregnancy rats”译为未确定词的双语例句
     The serum IGF-Ⅰand IGF-Ⅱlevels of pregnancy rats in model group were significantly lower than those of control group(P<0.01). The levels of IGF-Ⅰand IGF-Ⅱin L-arginine treated groups were increased significantly than those of model group(P<0.01).
     模型组大鼠血清IGF-Ⅰ、IGF-Ⅱ水平较对照组明显降低(P<0.01),小剂量和大剂量L-精氨酸防治组与模型组相比,IGF-Ⅰ、IGF-Ⅱ水平明显增高(P<0.01)。
短句来源
     rats in group B were introduced orally with powder of Chinese herbs (4 5 g/kg·d) during 1~11 days of pregnancy,rats in group C were injected with progesterone (8 mg/kg·d) during 1~11 days of pregnancy;
     A组为模型组 ; B、C组在孕 1~ 1 1d分别给予大剂量中药 (4 5g/kg·d)、P(8mg/kg·d) ,另设正常孕鼠对照 (D组 )。
短句来源
     The serum IGFBP-3 levels of pregnancy rats in model group were significantly higher than those of control group(P<0.01). The levels of IGFBP-3 in L-arginine treated groups were decreased significantly than those of model group(P<0.01)and there were statistical difference between L-arginine treated groups and control group(P<0.01).
     模型组大鼠血清IGFBP-3水平较对照组明显增高(P<0.01),小剂量和大剂量L-精氨酸防治组与模型组相比,IGFBP-3水平明显降低(P<0.01),与对照组亦有明显差异(P<0.01)。
短句来源
     Methods: N(G)nitroLargininemethylester (LNAME) was used to inhibite the synthesizing of NO in the third trimester of pregnancy rats. Indices including HGB, PLT, HCT, protein uria, serum endothelin (ET), thromboxane B2(TXB2), 6ketoPGF1α and blood pressure in pregnant rats were measured.
     方法:用一氧化氮合成酶抑制剂L-NAME抑制妊娠晚期大鼠(妊娠组)及未妊娠鼠(对照组)体内NO的合成,测定大鼠血压、尿蛋白、血小板(PLT)、血红蛋白(HGB)、红细胞压积(HCT)、血浆内皮素(ET)、血栓素B2(TXB2)、6-酮-前列腺素F1α(6-keto-PGF1α)水平。
短句来源
     There were no significant difference in the structure of corpus luteum and gonadotroph in hypophysis as well as in the level of serum progesterone of experimental and control groups, These results indicated that the anti-pregnant effect of RU486 in middle stage pregnancy rats was better than that in the early stage ones.
     黄体和脑垂体促性腺激素细胞的结构及血清孕酮水平与对照组比较无明显差异。 提示:RU486对大鼠抗中期妊娠效果比抗早孕好。
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  相似匹配句对
     Effect of sodium artesunate on pregnancy in rats
     青蒿琥酯钠对大鼠抗孕作用的研究(英文)
短句来源
     Effects of Antiendometrial Antibody on Pregnancy in Rats
     抗子宫内膜抗体对大鼠不孕及自然流产的影响
短句来源
     HLA-G and pregnancy
     HLA-G与妊娠
短句来源
     Abnormal Pregnancy
     异常妊娠
短句来源
     METHODS The rats
     方法用075%的腺嘌呤(W/W)长期饲养大鼠。
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  pregnancy rats
In contrast tolate-stage pregnancy rats, early-stage pregnancy animalsshowed a decrease of cysteamine-induced gastroduodenallesions.
      
On the 15th day of pregnancy rats were exposed for 2 h to the action of hypoxia equivalent to an altitude of 8000 m, and on the 18th day of pregnancy they were given three injections of [3H]thymidine.
      


On Day 7 of pregnancy rats were ovariectomized and blood samples were collected to measure serum progesterone.After that,5 mg of progesteronewere given subcutaneusly daily.The animals were sacrificed on Day 9 ofpregnancy.At autopsy the conceptuses,uterus and decidua were separatelyweighed and sectioned and examined under microscope.It was found that the level of serum progesterone decreased progressivelyafter ovariectomy.At 12 hours after ovariectomy the conceptuses began tochange,at the same time,the...

On Day 7 of pregnancy rats were ovariectomized and blood samples were collected to measure serum progesterone.After that,5 mg of progesteronewere given subcutaneusly daily.The animals were sacrificed on Day 9 ofpregnancy.At autopsy the conceptuses,uterus and decidua were separatelyweighed and sectioned and examined under microscope.It was found that the level of serum progesterone decreased progressivelyafter ovariectomy.At 12 hours after ovariectomy the conceptuses began tochange,at the same time,the level of serum progesterone was about 20% ofthe controls.However,the weight of the uterus and decidua only started todecrease at 16 hours after ovariectomy.Accordingly,it seemed that the changeof the conceptuses could be caused and abortion could be brought about whenthe level of serum progesterone decreased to about 20% of the controls.On Day 7 of pseudopregnancy rats were ovariectomized,after 24 hours,the weight of the decidua began to decrease.However,on Day 4 of pseudo-pregnancy,the weight of the dcidua did begin to decrease at 12 hours after ovariectomy.It was possible that on day 4 of pseudopregnancy the deciduawas more sensible to the decreasing of serum progerterone.

本文目的在于观察血清孕酮水平与早孕维持的关系。于大鼠妊娠第七天切除卵巢,并于切卵巢后不同时间取血,测定血清孕酮,以观察切卵巢后血清孕酮水平的变化。然后,各组分别于切除卵巢后不同时间开始补充外源性孕酮。于第九天处死,称胚珠、子宫和蜕膜的重量并做组织学检查,以观察切除卵巢后经过多长时间以及血清孕酮水平下降到什么程度将导致不可避免的流产,并分析通过干扰那些环节而导致流产。结果表明,切除卵巢后血清孕酮水平逐步下降,于切除卵巢后12小时,胚珠开始发生变化,此时血清孕酮水平为对照值的20%。切除卵巢后16小时,血清孕酮进一步下降,此时子宫及蜕膜重量才发生变化。这提示:“切除卵巢后12小时,当血清孕酮下降至对照水平的20%左右时,即可能引起胚珠的改变并导致流产”。为了观察切卵巢后蜕膜的变化,于大鼠假孕第七天切除卵巢,看到24小时后蜕膜重量降低并呈现组织学改变,但是在假孕第四天切除卵巢,12小时后即引起蜕膜改变。这说明,在假孕的不同时期,蜕膜对血清孕酮水平下降的敏感性不同。

By using the histochemical method, the electron microscopy and biochemical measurement, this study deals with the changes of the innervation of the uterus in tats induced by pregnancy. The results revealed that the adrenergic and cholinergic innervation of the uterus were reduced in advanced pregnancy. The content of noradrenaline(NE), expressed as ng/per gram wet weight was 194.79±2.85 in the control group and 78.56±0.48 in the late pregnancy group (P<0.005). The difference is statistically significant. Viewed...

By using the histochemical method, the electron microscopy and biochemical measurement, this study deals with the changes of the innervation of the uterus in tats induced by pregnancy. The results revealed that the adrenergic and cholinergic innervation of the uterus were reduced in advanced pregnancy. The content of noradrenaline(NE), expressed as ng/per gram wet weight was 194.79±2.85 in the control group and 78.56±0.48 in the late pregnancy group (P<0.005). The difference is statistically significant. Viewed under the electron microscopy, the number of axons/10,000 smooth muscle cell's cross section was remarkably reduced within the wall of the uterus of the late pregnancy rats. The degeneration nerves showed "condensation" or "empty" profiles were observed. In contrast to the previous report, in which the nerve muscle separation was described as a type of closecontact(CC) type with a gap less than 20 nm, our study revealed that the CC type of the nerve muscle separation was about 20% and the majority of the nerve muscle separation was usually over 100 nm in the uterus of the rat. The CC type of nerve muscle separation was very rare in the uterus of the late pregnancy rats. Based on this study and the available literature, the possible mechanism of the changes of the innervation of the uterus during pregnancy is discussed.

本实验应用组织化学、电镜和生物化学测定,对大鼠子宫妊娠期的植物性神经变化进行了观察。实验结果表明,随妊娠期的进展,大鼠子宫壁中肾上腺素能和胆碱能神经数量明显减少。子宫组织中去甲肾上腺素(NE)含量减低。NE含量以ng/g组织湿重表示,对照组为194.79±62.85,晚期妊娠组为78.56±30.48,呈高度显著性差异(P<0.005)。电镜观察表明,晚期妊娠子宫壁中的轴索数目明显减少,并可见“固缩型”和“空虚型”的退行性变的神经终末支。大鼠子宫神经和平滑肌的间隔,文献报告属紧密接触型,二者间距小于20 nm。本观察结果表明,大鼠子宫神经平滑肌间隔仅有20%属紧密接触型,大部分神经肌肉间隔在100 nm以上。妊娠期紧密接触型的比例更少。本文还对子宫妊娠期植物性神经变化的机制进行了讨论。

The effect of RU486 on early and middle stage of pregnant rats was observed with light and electronic microscopes. Two groups of pregnant rats were administered with the dose of 1. 25mg/ rat in 7th(d7) and 10th (d10) pregnant day respectively. After being administered for 24h 9 the middle stage of pregnant rats all aborted and decidua was necrosed; for 48h, uterus endometrium had been restored to normal. The lipid droplets in luteal cells increased, and the level of serum progesterone was significantly lower...

The effect of RU486 on early and middle stage of pregnant rats was observed with light and electronic microscopes. Two groups of pregnant rats were administered with the dose of 1. 25mg/ rat in 7th(d7) and 10th (d10) pregnant day respectively. After being administered for 24h 9 the middle stage of pregnant rats all aborted and decidua was necrosed; for 48h, uterus endometrium had been restored to normal. The lipid droplets in luteal cells increased, and the level of serum progesterone was significantly lower than that in the control group. The state of development of some embryos in two cases among the early pregnant rats were similar to that in the control group after being administered for 48h, embryo and placenta of others all disintegrated, but in two rats their uterus had been restored. There were no significant difference in the structure of corpus luteum and gonadotroph in hypophysis as well as in the level of serum progesterone of experimental and control groups, These results indicated that the anti-pregnant effect of RU486 in middle stage pregnancy rats was better than that in the early stage ones.

应用光、电镜方法观察RU486对早期和中期妊娠大鼠脑垂体、卵巢、子宫、胎盘及肝脏的影响。妊娠大鼠分别在受孕第7天(d7)和第10天(d10)给药1.25mg/只。中期妊娠大鼠给药后24h全部流产,蜕膜坏死;48h子宫内膜修复正常。黄体细胞内脂滴增多、退变。血清孕酮水平低于对照组。早期妊娠大鼠给药后48h,个别胚胎发育与对照组相似,其余胚胎和胎盘均解体,其中2例子宫已修复。黄体和脑垂体促性腺激素细胞的结构及血清孕酮水平与对照组比较无明显差异。提示:RU486对大鼠抗中期妊娠效果比抗早孕好。

 
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