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   ovarian epithelium 的翻译结果: 查询用时:0.046秒
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ovarian epithelium
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  卵巢上皮
     Results The percentage of strong positive cells in epithelial ovarian carcinoma (39.24%) is significant lower than that of nomal ovarian epithelium (81.82%) and benign tumors (75.76% ), (P < 0.05) .
     结果39.24%的卵巢上皮性癌、81.82%的正常卵巢上皮、75.76%的卵巢良性肿瘤组织中TFAR19蛋白呈强阳性表达,卵巢上皮性癌与卵巢良性肿瘤组织及正常卵巢上皮相比差异有显著性(P<0.05)。
短句来源
     Methods: Telomerase activity was measured quantitatively by Telomerase-PCR-ELISA in 25 samples of ovarian epithelium tumors (including 8 benign, 3 borderline-malignant, and 14 malignant tumors) and 6 samples of normal ovarian epithelia as control.
     方法:采用端粒酶PCR-ELISA法对25例卵巢上皮性肿瘤(8例良性、3例交界性和14例恶性)和6例正常卵巢表面上皮进行端粒酶活性定量检测。
短句来源
     A total of 323 genes whose expression level were larger than 3 times in HO-8910PM cell and normal ovarian epithelium cell was screened out.
     HO-8910PM细胞与正常卵巢上皮比较差异3倍以上共有323个基因。
短句来源
     A total of 323 genes with expression levels more than 3 times larger in HO-8910PM cells compared to normal ovarian epithelium cells were also detected.
     结果 人卵巢癌细胞系HO 8910细胞与正常卵巢上皮比较差异 3倍以上共有 35 5个基因。
短句来源
     [Results] There were 185 genes expressive differentia more than 5 times between human ovarian papillary serous cystadenocarcinoma and normal ovarian epithelium. Among these genes, 86 up-regulated (fluorescence intensity enhancement >5) and 99 down-regulated(fluorescence intensity weakening <0.2).
     [结果]卵巢浆液性乳头状囊腺癌与正常卵巢上皮比较,差异5倍以上共有185个基因,其中表达上调(其荧光强度增强>5)有86个,表达下调(其荧光强度减弱<0.2)有99个。
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  “ovarian epithelium”译为未确定词的双语例句
     The density of bFGF expression was (3.35± 3.52)% in normal ovarian epithelium, (19.25±21.73)% in benign tumor, (33.78± 10.86) % in borderline tumor and (48.18±12.93)% in malignant tumor.
     正常卵巢组织b F G F 密度为(335±352)% ,良性上皮性肿瘤细胞为(1925±2173)% ,交界型上皮性肿瘤组织细胞为(3378±1086)% ,卵巢癌细胞为(4818±1293)% 。
短句来源
     Methods:Normal human ovarian epithelium cells and human ovarian carcinoma cell strain SKOV3 were cultured in vitro. Peripheral blood lymphocytes were separated from normal individual and autologous tumor cells vaccines-ATV-NDV with human ovarian carcinoma cell strain 3AO were prepared. ATV-NDV,IL-12,IL-15,ATV-NDV+IL-12 and ATV-NDV+IL-15,in different concentration and action time,were respectively cultured with human peripheral blood lymphocytes.
     方法:制备人卵巢癌细胞株3AOATV-NDV瘤苗,将不同浓度的ATV-NDV、白细胞介素12(IL-12)、白细胞介素15(IL-15)、ATV-NDV+IL-12、ATV-NDV+IL-15分别与正常人外周血淋巴细胞混合培养,MTT法测定其刺激淋巴细胞增殖的程度及对肿瘤细胞的生长抑制率;
短句来源
     Results① Ovarian SCC perhaps originated from ovarian epithelium;
     结果①卵巢 SCC可能起源于卵巢的上皮组织;
短句来源
     Results The expression of pRb protein was significantly decreased in serous ovarian neoplasm's (46.2%) compared with that in normal ovarian epithelium (90%). No correlation was found between expression of pRb protein and FIGO stage of histological grade of serous ovarian cancer or post-operation survival rate (p>0.05).
     结果浆液性卵巢组织中pRb蛋白的表达阳性率为46.2%,明显低于正常卵巢组织(90%),而卵巢浆液性良、恶性肿瘤之间,高分化和中低分化浆液性囊腺癌之间,早期和中晚期浆液性囊腺癌之间pRb蛋白表达阳性率无明显差异(p>0.05),pRb蛋白表达阳性和阴性浆液性卵巢癌患者术后生存率也无明显不同(p>0.05)。
短句来源
     Methods Paraffin-embedded tissue sections of 10 cases of normal ovarian epithelium and 38 cases of serous ovarian tumor(8 cases of serous cystadenoma,6 cases of borderline serous cystadenoma,24 cases of different differentiated serous cystadenocatcinoma) were involved in this study,Immunohisto chemistry were performed to detect the expression of Cx43.The expression levels were quantified by image analysis.
     方法 应用SP免疫组织化学法检测Cx4 3在 10例正常卵巢组织及 38例卵巢浆液性肿瘤 (其中浆液性囊肿腺瘤 8例 ,交界性浆液性囊腺瘤 6例 ,不同分化程度的浆液性囊腺癌 2 4例 )中的表达 ,并采用计算机图像分析系统对Cx4 3的表达进行定量分析。
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  相似匹配句对
     Significance of telomerase activity in ovarian epithelium tumor
     卵巢上皮性肿瘤端粒酶活性定量检测
短句来源
     Effects of combined therapy on advanced epithelium ovarian carcinoma
     综合疗法治疗上皮型中晚期卵巢癌(附21例临床报告)
短句来源
     OVARIAN PREGNANCY
     卵巢妊娠
短句来源
     Ovarian Dysgerminoma
     卵巢无性细胞瘤
短句来源
     The epithelium of the oviduct is ciliated.
     输卵管上皮为纤 毛状。
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  ovarian epithelium
Among many differentially expressed genes, eIF2α kinase, a heme regulated inhibitor was down-regulated in ovarian epithelium cancer.
      
After entering pouches ("follicles") which are built up by the ovarian epithelium, yolk and yolk-shell can be observed in the oocytes.
      
Formation of the oocytes, the morphology of the funiculus, yolk synthesis in connection with the haemolymph, and the further destiny of the ovarian epithelium after egg deposition find special considerations.
      
Normal surface ovarian epithelium was weakly positve for both c-erbB-2 protein and EGFR.
      
The perfused ovarian epithelium had villous processes of varied architectural complexity with squamoid and cuboid epithelial cells.
      
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The influence of sex hormones on the differentiation of gonads and gonaducts in the fowl has been the concern of a large number of investigators. They studied the effects of various kinds of sex hormones on the sexual differentiation of chick embryos and young birds and discussed the mechanism of development of reproductive organs in relation to the action of sexual hormones. But most of the authors either did not use the embryos and the chicks of genotypically known sex as experimental materials or only investigated...

The influence of sex hormones on the differentiation of gonads and gonaducts in the fowl has been the concern of a large number of investigators. They studied the effects of various kinds of sex hormones on the sexual differentiation of chick embryos and young birds and discussed the mechanism of development of reproductive organs in relation to the action of sexual hormones. But most of the authors either did not use the embryos and the chicks of genotypically known sex as experimental materials or only investigated the action of sex hormones on the development of the reproductive systems anatomically. The present authors made use of the autosexing embryos and chicks as experimental materials, and investigated the action of sex hormones on the differentiation of gonads and gonaducts anatomically as well as histologically in order to elucidate the mechanism of sexual differentiation on a more sound basis.All the eggs used in this study were obtained from the crosses between barred hens and non-barred cocks, giving only barred males and non-barred females. The hormonal treatments were given by two different methods, one was injection of hormones into the un-incubated or incubating eggs, and the other was immersion of un-incubated eggs in hormone solutions. In the former, the female sex hormones diethylstilbestrol, estradiol, hexesterol and ovarian tissue extract and the male sex hormone testosterone were employed, while in the latter, however, only the female sex hormone diethylstilbestrol was used. The main results of the hormone treatments thus obtained are presented schematically in the accompanying table.Since in the initial stage of sexual differentiation, the gonads are amphisexual, the left gonad of birds possesses two components, an outer ovarian cortex and an inner portion, the medulla; the right gonad primordium, on the other hand, consists of only the medullary portion, generally lacking the incipient ovarian epithelium. The female hormones tend to activate the female component in embryos of either sex and suppress the male components. The male hormone has just the opposite effect, it stimulates the male component and suppresses the female component. After the treatment of female sex hormone, the gonads of genetic male birds tend to be flattened, with cortex thickened to form a kind of ovatestes. After the treatment of male hormone, on the contrary, the left gonad of the genetic female tends to be elongated, and to form a structure similar ??to that of the male sex cords, but the right gonad is not affected to any visible degree. In most of the cases, the latter remains to be small or degenerated completely.The degree of sex reversal depends to a large extent on the quantity of hormones given, the heavier the dosage used, the more complete with the sex reversal. But in no case complete sex reversal has been observed even though the dosage employed was as high as 2 mg. This suggests that the direction of sex differentiation is primarily controlled by the quantitative balance between the opposing sets of male and female determining genes. The moditications in the course of sexual differentiation as affected by the treatment of sex hormones are probably secondary in nature.In the development of male birds, the Müllerian ducts disappear entirely and the Wolffian ducts persist as the vasa differentia. In the case of females, the left Müllerian duct persists as the functional oviduct, the right one degenerating and the Wolffian ducts only persist in a rudimentary state. After hormone treatment, the Müllerian ducts persist, though somewhat hypertrophied, regardless whether the treated animals are genotypic males or females. This may be explained as either due to that the administrated hormones disturb the normal differentiation courses of the Müllerian ducts directly or due to that administrated hormones interfere with the normal differentiation of the gonads, and then cause the abnormal retention of the Müllerian ducts.

1. 试验用的鸡胚和雏鸡都是"芦花鸡♀×浦东鸡♂"的第一代杂种,遗传型雄性都是芦花斑纹,遗传型雌性都不是芦花斑纹.试验分二组,第一组是把雌性激素已雌酚、雌二醇、催情素、卵巢组织液及雄性激素丙酮睾丸素在入孵前或入孵后3~4天注入鸡蛋内,第二组是把鸡蛋在入孵前浸泡在己雌酚油剂、乳剂或其它溶液中.2. 蛋内注入或浸泡雌激素后,遗传型雄性鸡胚的性腺趋向扁平、皮质部增厚,形成卵睾.把丙酮睾丸素注入蛋内,少数遗传型雌性鸡胚的卵巢成长圆形、有形成精索的迹象.但都不能引起完全的性别转化.3. 用性激素处理鸡胚,不论是遗传型雌性的还是遗传型雄性的,都可诱导双输卵管的存留,不过在外观上左侧输卵管比较正常些,右侧多成盲囊等不规则形态,管内充满液体或淡黄色物质.4. 性腺有二个部分,外侧是胚质上皮,内层是雄性髓部.鸡胚性腺的分化最初是由雌性基因与雄性基因的量的平衡决定的,当性腺分化到一定程度后,性腺本身所分泌的性激素也起着很重要的作用.注射或浸泡后进入鸡胚的相反性激素只可使性腺分化发生局部改变,因为(1)进入的性激素是单一种类的,而鸡胚或雏鸡所分泌的性激素是有一定比例而且相互制约的,(2)性分化的方向最终还是受雌雄性基因的量的平衡决...

1. 试验用的鸡胚和雏鸡都是"芦花鸡♀×浦东鸡♂"的第一代杂种,遗传型雄性都是芦花斑纹,遗传型雌性都不是芦花斑纹.试验分二组,第一组是把雌性激素已雌酚、雌二醇、催情素、卵巢组织液及雄性激素丙酮睾丸素在入孵前或入孵后3~4天注入鸡蛋内,第二组是把鸡蛋在入孵前浸泡在己雌酚油剂、乳剂或其它溶液中.2. 蛋内注入或浸泡雌激素后,遗传型雄性鸡胚的性腺趋向扁平、皮质部增厚,形成卵睾.把丙酮睾丸素注入蛋内,少数遗传型雌性鸡胚的卵巢成长圆形、有形成精索的迹象.但都不能引起完全的性别转化.3. 用性激素处理鸡胚,不论是遗传型雌性的还是遗传型雄性的,都可诱导双输卵管的存留,不过在外观上左侧输卵管比较正常些,右侧多成盲囊等不规则形态,管内充满液体或淡黄色物质.4. 性腺有二个部分,外侧是胚质上皮,内层是雄性髓部.鸡胚性腺的分化最初是由雌性基因与雄性基因的量的平衡决定的,当性腺分化到一定程度后,性腺本身所分泌的性激素也起着很重要的作用.注射或浸泡后进入鸡胚的相反性激素只可使性腺分化发生局部改变,因为(1)进入的性激素是单一种类的,而鸡胚或雏鸡所分泌的性激素是有一定比例而且相互制约的,(2)性分化的方向最终还是受雌雄性基因的量的平衡决定的.所以性分化方向的改变是不完全的,而且随着时日的增进,逐渐回复到原来的性别.5. 性激素处理可以使鸡胚的的两个Müller氏管存留,不论是遗传型雌性的还是雄性的.这可能由于输入的性激素直接导致生理上的不正常,也可能由于性激素促进性腺的分化不正常,转而引起Müller氏管的不正常存留.6. 用性激素处理鸡胚,研究性别分化的机制,在理论上有一定的意义.但因处理后出雏率降低,性腺转化不完全,所以在处理技术进一步改进前,在生产实践上尚无应用价值.

Splicing variants of CD 44 molecules (CD 44 v) has been known to be involved in malignant transformation and metastasis of different types of human tumors. However, their status as well as role(s) in ovarian cancers are still in dispute. In this study, CD 44 expression patterns in normal ovarian epithelium,benign ovarian tumors and ovarian cancers were checked immunohistochemically using a series of monoclonal antibodies (MAbs) against the epitopes of standard form of CD...

Splicing variants of CD 44 molecules (CD 44 v) has been known to be involved in malignant transformation and metastasis of different types of human tumors. However, their status as well as role(s) in ovarian cancers are still in dispute. In this study, CD 44 expression patterns in normal ovarian epithelium,benign ovarian tumors and ovarian cancers were checked immunohistochemically using a series of monoclonal antibodies (MAbs) against the epitopes of standard form of CD 44 (CD 44 s) and CD 44 variant exons respectively. The results revealed that CD 44 v was negative in normal ovarian tissues; 4 out of 25 benign tumors were found with focally expressed variant exons 8 10 (v8 v10), but negative for other exons. In contrast, multiple isoforms of CD 44 v were detected in all of the ovarian cancer cell lines; among those isoforms,v7 was distinctively up regulated and commonly distributed. Our data thus suggest that expressions of CD 44 v especially v7 occur at relatively late stage of stepwised ovarian carcinogenesis which would become a new malignant biomarker and potential immunodiagnostic element for ovarian cancers.

细胞粘附因子CD44的变异型(CD44v)出现在多种肿瘤的恶性转化过程中并与这些肿瘤的转移能力密切相关。然而,CD44基因在良恶性卵巢肿瘤中的表达类型尚无定论。为此,本研究使用特异性识别CD44分子不同抗原决定簇的单克隆抗体,对正常卵巢组织以及良性和恶性肿瘤的CD44表达类型进行免疫组织化学分析。结果显示,CD44v在正常卵巢内呈阴性;25例良性肿瘤中,21例阴性,4例有灶局性变异型外显子v8-v10的表达;相反,26例卵巢癌手术切除标本和2株卵巢癌细胞系Caov3和Ovca3有多种形式的CD44v存在;其中,v7的表达明显上调。2例交界性肿瘤的表达形式与卵巢癌相似,但呈灶局阳性。本结果因而提示,CD44v尤其是v7出现在卵巢癌恶性转化的过程中;它(们)可能成为该类肿瘤新的生物标志物并在癌细胞转移中起促进作用。

Objective To determine the effect of basic fibroblast growth factor (bFGF) on the biological behaviour of ovarian epithelial neoplasm.Methods Ten cases of normal ovarian tissues and eighty cases of ovarian epithelial tumor tissues were detected by immunohistochemical methods. Mias 2000 Picture Analysis System was used to study the relationship of bFGF expression intensity and microvessel count、FIGO stage、pathological grade and classification of ovarian epithelial neoplasm.Results ①Expression of bFGF was...

Objective To determine the effect of basic fibroblast growth factor (bFGF) on the biological behaviour of ovarian epithelial neoplasm.Methods Ten cases of normal ovarian tissues and eighty cases of ovarian epithelial tumor tissues were detected by immunohistochemical methods. Mias 2000 Picture Analysis System was used to study the relationship of bFGF expression intensity and microvessel count、FIGO stage、pathological grade and classification of ovarian epithelial neoplasm.Results ①Expression of bFGF was mainly in cytoplasm and nucleus in several cells of borderline and malignant tumor.②The expression intensity of bFGF was closely related to the malignant degree of ovarian epithelial neoplasm. The density of bFGF expression was (3.35± 3.52)% in normal ovarian epithelium, (19.25±21.73)% in benign tumor, (33.78± 10.86) % in borderline tumor and (48.18±12.93)% in malignant tumor. The results indicated that bFGF might play an important role in carcinogenesis of ovarian epithelial neoplasm.③The expression intensity of bFGF was increased with the FIGO stage of ovarian tumor.④The expression intensity of bFGF was increased accompaning with the decrease of differentiation degree in ovian neoplasm.⑤In borderline tumor, expression intensity of bFGF in serous cystadenoma was significantly higher than in mucinous cystadenoma, which indicated bFGF might be an important factor in canceration of ovarian epithelial neoplasm.Conclusion bFGF may play important roles in carcinogenesis, development, invasion and metastasis of ovarian epithelial neoplasm.

目的 探讨碱性成纤维细胞生长因子(b F G F)在卵巢上皮性肿瘤的生物学行为中的作用。方法 应用免疫组织化学技术对10 例正常卵巢组织和80 例卵巢上皮性肿瘤进行对照研究,同时应用 Mias2000 图像分析系统进行定量分析,并研究恶性肿瘤中b F G F的表达强度与临床分期以及肿瘤类型和病理分级间的关系。结果 ①b F G F 主要在卵巢上皮性肿瘤细胞浆内表达,在交界型和恶性肿瘤中,部分阳性细胞同时存在细胞核表达。②b F G F的表达强度随卵巢上皮性肿瘤的恶性程度增加而增强。正常卵巢组织b F G F 密度为(335±352)% ,良性上皮性肿瘤细胞为(1925±2173)% ,交界型上皮性肿瘤组织细胞为(3378±1086)% ,卵巢癌细胞为(4818±1293)% 。提示b F G F可能在卵巢癌的发生中起重要作用。③b F G F的表达强度随 F I G O 分期的增高而增强。④b F G F的表达强度随卵巢癌的分化程度降低而增强。⑤卵巢交界型浆液性囊腺瘤中b F G F 的表达较交界型粘液性囊腺瘤明显增高,表明b F G F在肿瘤恶变中可能起重要作用。结论b F G F在卵巢肿...

目的 探讨碱性成纤维细胞生长因子(b F G F)在卵巢上皮性肿瘤的生物学行为中的作用。方法 应用免疫组织化学技术对10 例正常卵巢组织和80 例卵巢上皮性肿瘤进行对照研究,同时应用 Mias2000 图像分析系统进行定量分析,并研究恶性肿瘤中b F G F的表达强度与临床分期以及肿瘤类型和病理分级间的关系。结果 ①b F G F 主要在卵巢上皮性肿瘤细胞浆内表达,在交界型和恶性肿瘤中,部分阳性细胞同时存在细胞核表达。②b F G F的表达强度随卵巢上皮性肿瘤的恶性程度增加而增强。正常卵巢组织b F G F 密度为(335±352)% ,良性上皮性肿瘤细胞为(1925±2173)% ,交界型上皮性肿瘤组织细胞为(3378±1086)% ,卵巢癌细胞为(4818±1293)% 。提示b F G F可能在卵巢癌的发生中起重要作用。③b F G F的表达强度随 F I G O 分期的增高而增强。④b F G F的表达强度随卵巢癌的分化程度降低而增强。⑤卵巢交界型浆液性囊腺瘤中b F G F 的表达较交界型粘液性囊腺瘤明显增高,表明b F G F在肿瘤恶变中可能起重要作用。结论b F G F在卵巢肿瘤的发生、生长、浸润和转移等过程中起着重要作用 ?

 
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