Objective To investigate the platelet activation in patients with idiopathic nephrotic syndrome (NS),Method Using ELISA, plasma 11-dehydrothromboxane B2(DH-TXB2) and thromboxane B2(TXB2) were detected in 36 NS patients and 20 controls.
In all, 177 cases presented with primary nephrotic syndrome; all had complicated courses and most were either corticosteroid-dependent or-resistant.
Primary nephrotic syndrome in Arab children in Kuwait
Fifty-five Arab children with primary nephrotic syndrome (PNS) were seen at two regional hospitals in Kuwait over a 5-year period.
A prospective study was performed to evaluate the efficacy of chlorambucil in inducing long-term remission in children with steroid-dependent or cyclophosphamide-resistant primary nephrotic syndrome (NS).
The study includes 150 children with primary nephrotic syndrome (NS), aged 16 months to 13 years with a median age of 5 years.
Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome
Treatment with cyclosporin of patients with idiopathic nephrotic syndrome
The prognosis of idiopathic nephrotic syndrome was transformed with the use of corticosteroids and immunosuppressive drugs.
Despite these drawbacks, preliminary results showed that approximately two-thirds of patients with idiopathic nephrotic syndrome resistant to other therapy clearly benefited from cyclosporin treatment, whereas only 7% suffered severe side effects.
Membranous nephropathy, a disease characterized by an accumulation of immune deposits on the outer aspect of the glomerular basement membrane, is the most common cause of idiopathic nephrotic syndrome in white adults.