Marterials and the: Using Seldinger's method, 12 cases received methotrexate (MTX) perfusion throughthe superselective uterus artery catheterization,then embolism of uterus artery with spongia Gelatim were applied.
[Methods] Twenty-seven patients with spontaneous rupture of primary liver cancer were treated in our hospital from 1981 to 1998 to 1998.The treatment includad drainage after flushing, filling and repairing with omentum or gelatinsponge, hepatic artery ligation, hepatic artery intubation chemotherapyi and selective hepatectomy.
Methods New Zealand rabbits with hepatic Vx-2 carcinoma were managed with normal saline (experimental group 1), normal saline plus lipiodol (experimental group 2), and As 2O 3 plus lipiodol (experimental group 3) respectively by TACE once, whereas experimental group 4 was treated with As 2O 3 by transcatheter arterial infusion(TAI) for 7 days consecutively.
Chemothera-peutic agents for continuous hepatic arterial infusion used were calcium folinate 200 mg/m2 , d1-d2/d14-d15, and fluorouracil 2 000-2 500 mg/m2 d1-d2/d14-d15,cisplatin 50 mg/m2 d1 or oxaliplatin 100-130 mg/m2 d1 .Results An overall response rate (CR+ PR) of the cases was 59.0% .
Surgical multimodalities therapy was carried out in unresectable cases,including hepatic arterial infusion 125 I or 131 I lipiodl anticancer drug targeting therapy injecting into neoplasm with anhydous alcohol interventional treatmemt after surgery chemotherapy and biotherapy and so on,with the results of 1 3 5 year survival rates of 52 6% 18 4% 6 4% respectively.
Methods The rabbits with implanted VX_2 carcinoma in the left liver lobe were randomized into 5 groups. In group A,the rabbits received a hepatic arterial infusion of saline and then exposed to an 40kHz and 24kA/min external alternating electromagnetic field(E)for 30 min.