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psoriasis models
相关语句
  银屑病病理模型
     Effects of Cyclosporine A Liposome Gel on Experimental Psoriasis Models
     环孢素脂质体凝胶剂对实验性银屑病病理模型的影响
短句来源
     AIM The purpose is to study the effects of cyclosporine A liposome gel on experimental psoriasis models.
     目的 探讨环孢素脂质体凝胶剂局部用药对各种银屑病病理模型的影响。
短句来源
  “psoriasis models”译为未确定词的双语例句
     Effect of Xianfangxiaoyin(仙方消银)Tablets on Vaginal Epithelium Mitosis in Mouse Psoriasis Models
     仙方消银片对模拟银屑病模型小鼠阴道上皮细胞有丝分裂的影响
短句来源
  相似匹配句对
     models;
     五、发展的模式;
短句来源
     Effects of boningmycin on pathological models of psoriasis
     博宁霉素对银屑病试验模型的影响
短句来源
     group 2, psoriasis-like models group;
     组2(造模组)镜下可见广泛角化过度及灶性角化不全,其中2例角化不全部位可见Munro微脓疡;
短句来源
     Psoriasis and Apoptosis
     银屑病与细胞凋亡
短句来源
     The Power of Models
     榜样的力量
短句来源
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AIM The purpose is to study the effects of cyclosporine A liposome gel on experimental psoriasis models. METHODS The vaginal epithelium mitosis of estrone periodical mice and the formation of mouse tail scale epidermis were used as the epidermis hyperplasia model and the epidermis parakeratosis model, respectively. Additionally, propranolol hydrochloride and dinitrofluorobenzene (DNFB) were used to induce experimental psoriasis model and contact sensitivity in guinea pig. RESULTS ...

AIM The purpose is to study the effects of cyclosporine A liposome gel on experimental psoriasis models. METHODS The vaginal epithelium mitosis of estrone periodical mice and the formation of mouse tail scale epidermis were used as the epidermis hyperplasia model and the epidermis parakeratosis model, respectively. Additionally, propranolol hydrochloride and dinitrofluorobenzene (DNFB) were used to induce experimental psoriasis model and contact sensitivity in guinea pig. RESULTS The results showed that the topical application of CsA liposome gel significantly inhibit the mitosis of mouse vaginal epithelium and promoted the formation of mouse tail scale epidermis. Cyclosporine A can also significantly inhibites the experimental psoriasis induced by propranolol and DNFB induced contact sensitivity. CONCLUSION The topical administration of cyclosporine A liposome gel has good efficacy in treating psoriasis by inhibiting the epidermis hyperplasia, parakeratosis and infiltration of lymphocytes.

目的 探讨环孢素脂质体凝胶剂局部用药对各种银屑病病理模型的影响。方法 采用雌激素周期小鼠阴道上皮细胞有丝分裂模型、小鼠尾部鳞片表皮颗粒层形成模型、盐酸普萘洛尔致豚鼠耳部皮肤银屑病样皮损模型、2 ,4-二硝基氟苯致豚鼠接触性皮炎模型 ,观察环孢素脂质体凝胶剂局部用药后的改善作用。结果 环孢素脂质体凝胶剂局部用药能显著抑制小鼠阴道上皮细胞分裂、促进小鼠尾部鳞片表皮颗粒层形成 ,并显著抑制盐酸普萘洛尔所致的表皮异常角化与增殖 ;对于 2 ,4-二硝基氟苯所致豚鼠接触性皮炎模型亦有明显的抑制作用 ,可使皮肤组织中的淋巴细胞浸润减少。结论 环孢素脂质体凝胶剂局部用药对银屑病表皮细胞增生、角化不全或异常角化、淋巴细胞浸润等病理改变具有良好的治疗效果

Objective This research is related to the affection on mouse psoriasis model by controlling the use of tetramethelpyrazine(TMP).Methods The researcher injects different amount of TMP(5~15 mg·mg -1 )to observe the different result of mouse on its epithelial cells of vagina in karyokinesis,and the changes on tail scale.Results The different amount of TMP experiment indicates that the use of TMP obviously decrease the mouse epithelial cells of vagina in karyokinesis,and the TMP leads to the increase...

Objective This research is related to the affection on mouse psoriasis model by controlling the use of tetramethelpyrazine(TMP).Methods The researcher injects different amount of TMP(5~15 mg·mg -1 )to observe the different result of mouse on its epithelial cells of vagina in karyokinesis,and the changes on tail scale.Results The different amount of TMP experiment indicates that the use of TMP obviously decrease the mouse epithelial cells of vagina in karyokinesis,and the TMP leads to the increase of granular layer on mouse tail scale.Conclusion TMP may obviously decrease the mouse epithelial cells of vagina in karyokinesis,and may increase the granular layer of its tail scale.

目的 研究川芎嗪对小鼠银屑病模型的影响。方法 采用腹腔注射已烯雌酚制备小鼠银屑病实验模型[1] ,从腹腔分别注射不同剂量 (5mg/kg~ 15mg/kg)的川芎嗪 ,观察小鼠阴道上皮细胞及尾部鳞片的变化。结果 川芎嗪各剂量组使小鼠阴道上皮细胞有丝分裂指数均明显降低 ;小鼠尾部鳞片的颗粒层形成数增高 ,且有剂量依赖性。结论 川芎嗪对银屑病实验模型小鼠阴道上皮细胞有丝分裂有明显抑制作用 ;对小鼠尾部鳞片中颗粒层有增加作用。

Purpose To study the therapeutic effects of recombinant human interleukin-11 (rhIL-11) on the formation of mouse-tail epidermis granular layer and the level of IL-2 in serum.Methods The formation of mouse-tail scale epidermis was used as the epidermis parakeratosis model, and different groups of mouse were treated with rhIL-11 or methotrexate. Its action in regulating the formation of mouse-tail epidermis granular layer and the level of IL-2 was observed.Results The rhIL-11 significantly promoted the formation...

Purpose To study the therapeutic effects of recombinant human interleukin-11 (rhIL-11) on the formation of mouse-tail epidermis granular layer and the level of IL-2 in serum.Methods The formation of mouse-tail scale epidermis was used as the epidermis parakeratosis model, and different groups of mouse were treated with rhIL-11 or methotrexate. Its action in regulating the formation of mouse-tail epidermis granular layer and the level of IL-2 was observed.Results The rhIL-11 significantly promoted the formation of mouse-tail epidermis granular layer and decreased the level of IL-2 in serum. Conclusion The rhIL-11 has good efficacy in treating animal psoriasis model by inhibiting keratinocyte proliferation and parakeratosis and by decreasing the level of IL-2.

目的观察重组人白细胞介素-11(rhIL-11)对小鼠尾部表皮颗粒层生成和血清白细胞介素-2(IL-2)水平的影响。方法采用小鼠尾部鳞片表皮颗粒层形成模型,不同组别的小鼠给予rhIL-11或甲氨喋呤,观察其对鼠尾鳞片表皮颗粒层和血清IL-2含量的影响。结果rhIL-11可显著促进小鼠尾部鳞片表皮颗粒层形成(P<0.01),并显著抑制血清IL-2的水平(P<0.01)。结论rhIL-11可抑制角质细胞增殖分化不全和减少促发因子IL-2的生成,对银屑病具有较好的防治作用。

 
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