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gerbil hippocampus
相关语句
  沙土鼠海马
     CHANGES OF INDUCED HSP70 GENE EXPRESSION IN GERBIL HIPPOCAMPUS AFTER FOREBRAIN ISCHEMIA
     脑缺血-复灌沙土鼠海马HSP70基因的表达变化
短句来源
     Methods A gerbil ischemia -reperfusion model was established by bilateral carotid artery occlusion (BCAO), Using human HSP70 genomic segment (600bp) as a probe ,the HSP70mRNA levels were examined in gerbil hippocampus by dot hybridization and Northern blot analyses.
     方法以蒙古沙土鼠双侧颈总动脉结扎(BCAO)建立全脑缺血复灌模型,用人的HSP70基因探针,通过斑点杂交和Northern印迹分析观察沙土鼠海马HSP70mRNA水平。
短句来源
     Effect of L-NAME on cGMP production in the gerbil hippocampus after recirculation following ischemia
     L-NAME对沙土鼠海马区cGMP作用的研究
短句来源
     Objective To examine the changes of HSP70mRNA levels in gerbil hippocampus during the course of ischemia and reperfusion and the impact of varied ischemic degrees on the induction of this gene.
     目的研究沙土鼠海马HSP70基因在缺血-复灌过程中的表达变化,以及不同缺血程度对该基因诱导表达的影响。
短句来源
     EXPRESSION OF BRAIN-DERIVED ERYTHROPOIETIN IN GERBIL HIPPOCAMPUS SUBJECTED TO TRANSIENT FOREBRAIN ISCHEMIA
     脑源性促红细胞生成素在短暂性前脑缺血沙土鼠海马的表达变化
短句来源
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  “gerbil hippocampus”译为未确定词的双语例句
     INFLUENCE OF CEREBRAL ISCHEMIA AND INTRAPERITONEALINJECTION OF MK801 ON THE EXPRESSION OF IL-1 TYPE I RECEPTOR mRNA IN GERBIL HIPPOCAMPUS
     脑缺血及腹腔注射MK801后对海马IL-1I型受体mRNA表达的影响
短句来源
     Effect of L -NNA on apoptosis in the gerbil hippocampus after recirculation following ischemia
     L-NNA对脑缺血再灌注后海马区细胞凋亡的影响
短句来源
     Effect of hyperbaric oxygen on apoptosis in CA_1 pyramidal cell layer of gerbil hippocampus following forebrain ischemia reperfusion injury
     高压氧治疗对沙土鼠脑缺血再灌注海马CA_1区神经元凋亡的影响
短句来源
     Hippocampal delayed neuronal death(DND)model was produced by bilateral carotid arteries occluded for 10 min with 7 day reperfusion. Effect of GPM on DND of gerbil hippocampus was examined by counting the neuronal density and histologic changes in CA_1sector.
     本实验通过结扎沙土鼠双侧颈总动脉10分钟再灌流7天,造成海马迟发性神经元死亡(Delayed Neuronal Death,DND)模型,用海马CA_1区神经元密度作为指标,观察绞股蓝总皂甙(GPM)对海马DND的影响。
短句来源
     Effect of L-NAME on Activating Mechanism of Astrocyte in the Gerbil Hippocampus After Re-circulation Following Ischemia
     L-NAME对沙土鼠脑缺血再灌流后海马区星形胶质细胞活化的作用机制研究
短句来源
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  相似匹配句对
     Effect of Ca~(2+) on cGMP production in the gerbil hippocampus
     钙离子对沙土鼠海马区cGMP作用的研究
短句来源
     Stress and hippocampus
     应激与海马
短句来源
     ORIGINS OF ACETYLCHOLINESTERASE-CONTAINING PROJECTIONS IN DORSAL HIPPOCAMPUS OF MONGOLIAN GERBIL
     蒙古种沙土鼠背海马胆碱能投射来源
短句来源
     THE ANGIOARCHITECTURE OF HIPPOCAMPUS IN RAT
     大鼠海马的血管构筑
短句来源
     AN INVESTIGATION OF ECOLOGY OF GERBIL
     长爪沙鼠的一些生态学资料
短句来源
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  gerbil hippocampus
The neuroprotective effects of (-)deprenyl in the gerbil hippocampus following transient global ischemia
      
Adult treatment with methamphetamine transiently decreases dentate granule cell proliferation in the gerbil hippocampus
      
Adult treatment with haloperidol increases dentate granule cell proliferation in the gerbil hippocampus
      
We examined age-dependent changes in Rip immunoreactivity and its protein level in the gerbil hippocampus during normal aging using immunohistochemistry and Western blot analysis with Rip antibody, an oligodendrocyte marker.
      
Chronological Distribution of Rip Immunoreactivity in the Gerbil Hippocampus During Normal Aging
      
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DND in the gerbil hippocampus was performed by bilateral occlusion of carotid arteries for 20 min followed by reperfusion 2 or 7 days. The contents of Ca~(2+) and MDA in drosal hippocampus were measured after two days reperfusion. Neuronal density in CA1 sector of hippocampus was used as an parameter. Effects of nimodipine and Superoxide dismutase (SOD) on DND in hippocampus were observed after 7 days reperfusion.The results indicated that the levels of Ca~(2+) and MDA were increased...

DND in the gerbil hippocampus was performed by bilateral occlusion of carotid arteries for 20 min followed by reperfusion 2 or 7 days. The contents of Ca~(2+) and MDA in drosal hippocampus were measured after two days reperfusion. Neuronal density in CA1 sector of hippocampus was used as an parameter. Effects of nimodipine and Superoxide dismutase (SOD) on DND in hippocampus were observed after 7 days reperfusion.The results indicated that the levels of Ca~(2+) and MDA were increased significantly. DND in hippocampal CA1 sector was ameliorated by both nimodipine and SOD significantly. It was suggested that Ca~(2+) and Iipid peroxidation play an important role in the development of DND hippocampus after transient forebrain ischemia in gerbils. Calcium Antagonist and free radical scavenger have obvious protective effects on DND in hippocampus.

本实验通过结扎沙土鼠双侧颈总动脉20分钟后再灌流2天或7天造成海马迟发性神经元死亡(DND)模型,检测背侧海马Ca~(2+)及脂质过氧化物含量的变化,并用海马CA_1区神经元密度作为指标,观察尼莫地平及超氧化物歧化酶(SOD)对海马DND的影响。结果:再灌流2天后背侧海马组织Ca~(2+)及MDA含量增加;尼莫地平及SOD均可改善海马CA_1区DND,使海马CA_1区神经元密度增加。本实验提示:Ca~(2+)及氧自由基导致的脂质过氧化物在短暂性脑缺血后海马DND的发生中起重要作用,钙拮抗剂及自由基清除剂对海马DND有保护作用。

Hippocampal delayed neuronal death(DND)model was produced by bilateral carotid arteries occluded for 10 min with 7 day reperfusion.Effect of GPM on DND of gerbil hippocampus was examined by counting the neuronal density and histologic changes in CA_1sector.The average neuronal density((?)±SD)in NS group.GPM-I,GPM-Ⅱ group was 107.50±6.63/mu,146.18±19.75/mm and 165.30±9.24/mm respectively.Compared with NS contral group,both neuronal density in GPM-I group and GPM-Ⅱ group were significantly increased(P<0.01;P<0.0001;respectively).The...

Hippocampal delayed neuronal death(DND)model was produced by bilateral carotid arteries occluded for 10 min with 7 day reperfusion.Effect of GPM on DND of gerbil hippocampus was examined by counting the neuronal density and histologic changes in CA_1sector.The average neuronal density((?)±SD)in NS group.GPM-I,GPM-Ⅱ group was 107.50±6.63/mu,146.18±19.75/mm and 165.30±9.24/mm respectively.Compared with NS contral group,both neuronal density in GPM-I group and GPM-Ⅱ group were significantly increased(P<0.01;P<0.0001;respectively).The results sugest that GPM significantly protected against hippocampal DND following transient cerebral ischemia in the gerbil.

本实验通过结扎沙土鼠双侧颈总动脉10分钟再灌流7天,造成海马迟发性神经元死亡(Delayed Neuronal Death,DND)模型,用海马CA_1区神经元密度作为指标,观察绞股蓝总皂甙(GPM)对海马DND的影响。NS组、GPM-I组和GPM-Ⅱ组的CA_1区神经元密度分别是107.50±6.63、146.18±19.75和165.30±9.24。GPM-I组、GPM—Ⅱ组与NS组比较P<0.01,P<0.0001。均有高度显著性差异。结果表明绞股蓝总皂甙对短暂性脑缺血后海马DND有明显保护作用。

OBJECTIVE: To observe effects of L-NAME on cGMP production in the gerbil hippocampus after recirculation following ischemia. METHOD: Both vessels occlusion and immunofluorescent methods in gerbil hippocampal tissue slice incubated in vitro were used. RESULTS: L-NAME inhibited cGMP production. CONCLUSION: L-NAME is a strong inhibitor of NOS (nitric oxide synthase). The role of endogenous NO mediated cGMP synthesis is inhibited by the L-NAME.

目的:探讨NOS抑制剂LNAME(左旋硝基精氨酸甲酯)对沙土鼠海马区环磷酸鸟苷(cGMP)的影响。方法:钳夹沙土鼠的双侧颈总动脉制造脑缺血模型,应用免疫荧光法染色,以便观察cGMP浓度的变化及分布。结果:LNAME抑制cGMP的合成。结论:LNAME是一氧化氮合酶(NOS)强有力的抑制剂,抑制了NO及其介导的cGMP的合成

 
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