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benign focal hepatic
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  肝良性占位
     Objective To observe the perfusion pattern of benign focal hepatic lesions using contrast agent SonoVue and real-time contrast imaging sonography and to investigate the type specific diagnostic value in benign focal hepatic lesions.
     目的利用超声造影剂SonoVue及实时超声造影技术观察肝良性占位病变造影剂灌注特点,探讨其对肝良性占位病变分类诊断的意义。
短句来源
     Conclusion The SonoVue contrast-enhanced ultrasound and second harmonic imaging reveals dynamic enhancement features of benign focal hepatic lesions,which is helpful to the diagnosis and differential diagnosis.
     结论SonoVue超声造影二次谐波成像技术能动态显示病灶增强特征,有助于肝良性占位病变的诊断及鉴别诊断。
短句来源
     Application of SonoVue contrast-enhanced ultrasound in benign focal hepatic lesions.
     SonoVue超声造影在肝良性占位病变诊断中的应用
短句来源
     Benign focal hepatic lesions: pulse inversion real-time imaging with the contrast agent SonoVue
     肝良性占位病变低机械指数反向脉冲谐波实时超声造影研究
短句来源
     Conclusions Low mechanical index real-time contrast sonography is sensitive and accurate in demonstrating hemodynamic features of most benign focal hepatic lesions,and it can be a promising technique in noninvasive type specific diagnosis of benign focal hepatic lesions.
     结论低机械指数反向脉冲谐波实时超声造影可准确显示大多数肝良性占位病灶的不同灌注特点,对分类诊断具有重要价值。
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  “benign focal hepatic”译为未确定词的双语例句
     The Kupffer-cell-count ratio was 1.54±0.47, 0.74±0.30, 0.32±0.09 and 0.28±0.07 for the benign focal hepatic lesions, well-differentiated HCC, moderately differentiated HCC and poorly differentiated HCC, respectively. There was significant difference in the Kupffer-cell-count ratio between the benign focal hepatic lesions and malignant ones (P<0.05).
     良性局灶性肝病与恶性病灶包括高分化、中分化、低分化HCC的Kupffer细胞计数比率存在不同,分别为1·54±0·47、0·74±0·30、0·32±0·09、0·28±0·07,差异有显著性(P<0·05)。
短句来源
  相似匹配句对
     B. Benign;
     B.良性肿瘤:膨胀性骨破坏;
短句来源
     Laparoscopy for hepatic benign lesions
     腹腔镜诊治肝脏良性病变
短句来源
     Application of SonoVue contrast-enhanced ultrasound in benign focal hepatic lesions.
     SonoVue超声造影在肝良性占位病变诊断中的应用
短句来源
     The clinical value of hepatic transit time for differentiating benign and malignant focal lesion in liver
     超声造影剂肝渡越时间对肝良恶性病变诊断的临床意义
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     Diagnosis of Focal Hepatic Iesions with MRI
     MRI对肝局灶病变的诊断价值
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  benign focal hepatic
However, metastatic liver tumors sometimes coexist with benign focal hepatic lesions like hemangiomas or cysts.
      


Objective To determine the value of Feridex-enhanced MRI for detection of focal hepatic lesions and analyze its relevant pathological basis. Methods The images obtained by MRI and CT in 26 patients with pathologically and clinically confirmed 61 focal hepatic lesions were prospectively analyzed to compare the detection value among 3 different methods of enhanced helical CT, Feridex-enhanced MRI and unenhanced and Feridex-enhanced MRI. Thirty-two hepatic lesions in 20 patients were stained by immunohistochemical...

Objective To determine the value of Feridex-enhanced MRI for detection of focal hepatic lesions and analyze its relevant pathological basis. Methods The images obtained by MRI and CT in 26 patients with pathologically and clinically confirmed 61 focal hepatic lesions were prospectively analyzed to compare the detection value among 3 different methods of enhanced helical CT, Feridex-enhanced MRI and unenhanced and Feridex-enhanced MRI. Thirty-two hepatic lesions in 20 patients were stained by immunohistochemical method to calculate the Kupffer-cell-count ratio of each focal lesion. Results For the enhanced helical CT group, Feridex-enhanced MRI group and unenhanced and Feridex-enhanced MRI group, the diagnostic sensitivity was 72%, 82% and 93% (P<0.05), specificity 92%, 96% and 96% (P>0.05) and accuracy 78%, 82% and 93% (P<0.05), respectively. The Kupffer-cell-count ratio was 1.54±0.47, 0.74±0.30, 0.32±0.09 and 0.28±0.07 for the benign focal hepatic lesions, well-differentiated HCC, moderately differentiated HCC and poorly differentiated HCC, respectively. There was significant difference in the Kupffer-cell-count ratio between the benign focal hepatic lesions and malignant ones (P<0.05). Conclusions Feridex-enhanced MRI is superior to enhanced helical CT in detection of focal hepatic lesions. The differences in Kupffer-cell-count ratio and focal lesions are the pathological basis for Feridex-enhanced MRI to detect the lesions.

目的前瞻性评价菲立磁增强扫描对局灶性肝病的检出价值及其病理基础。方法收集经临床、手术病理为诊断金标准证实的26例61个肝局灶性病变,前瞻性对比评价螺旋CT增强扫描、MRI平扫及联合分析MRI平扫+菲立磁增强图像对局灶性肝病的诊断价值。其中20例32个病灶行免疫组化抗CD-68染色,并计数各局灶性病变的Kupffer细胞计数比率。结果螺旋CT增强扫描、MRI平扫及联合分析MRI平扫+菲立磁增强诊断敏感性分别为72%、82%、93%,P<0·05;特异性分别为92%、96%、96%,P>0·05,准确性分别为78%、86%、94%,P<0·05。良性局灶性肝病与恶性病灶包括高分化、中分化、低分化HCC的Kupffer细胞计数比率存在不同,分别为1·54±0·47、0·74±0·30、0·32±0·09、0·28±0·07,差异有显著性(P<0·05)。结论菲立磁增强MRI对肝局灶性病变的检出价值优于螺旋CT增强扫描。局灶性病变与非肿瘤区肝组织内Kupffer细胞含量的差异是菲立磁增强MRI病灶检出的病理基础。

Objective To observe the perfusion pattern of benign focal hepatic lesions using contrast agent SonoVue and real-time contrast imaging sonography and to investigate the type specific diagnostic value in benign focal hepatic lesions.Methods One hundred and three patients with histologically proven benign focal hepatic lesions(33 hemangiomas,11 regenerative cirrhotic nodules,4 adenomas,6 lesions of focal nodular hyperplasia,11 lesions of focal necrosis,4 inflammatory pseudotumors,18...

Objective To observe the perfusion pattern of benign focal hepatic lesions using contrast agent SonoVue and real-time contrast imaging sonography and to investigate the type specific diagnostic value in benign focal hepatic lesions.Methods One hundred and three patients with histologically proven benign focal hepatic lesions(33 hemangiomas,11 regenerative cirrhotic nodules,4 adenomas,6 lesions of focal nodular hyperplasia,11 lesions of focal necrosis,4 inflammatory pseudotumors,18 hepatic abscesses,14 lesions of local fatty change or fatty sparing,2 angiomyolipomas) were examined continuously for 4 minutes by low mechanical index(MI(0.09)~(0.15)) pulse inversion sonography after intravenous injection of(2.4) ml of SonoVue.Results(81.8%)(27/33) of hemangiomas showed peripheral nodular and centripetal enhancement;(83.3%)(5/6) of focal nodular hyperplasias showed central spoke wheel-shaped enhancement pattern during early arterial phase;enhancement pattern was similar to that of surrounding liver parenchyma during all phases in(90.9%)(10/11) of regenerative cirrhotic nodules and in 100%(14/14) of focal fatty change or fatty sparing;100%(6/6)of adenoms and angiomyolipomas showed diffuse homogeneous or heterogeneous enhancement during arterial phase and(83.3%)(5/6) lesions remained isoehoic during the delay phase;no internal enhancement was observed in(92.8%)(13/14) lesions of focal necrosis and inflammatory pseudo tumors during all phases;coallescent appearance,lack of internal enhancement and sharp boundary of necrotic cavity were observed in(94.4%)(17/18) of hepatic abscesses.Conclusions Low mechanical index real-time contrast sonography is sensitive and accurate in demonstrating hemodynamic features of most benign focal hepatic lesions,and it can be a promising technique in noninvasive type specific diagnosis of benign focal hepatic lesions.

目的利用超声造影剂SonoVue及实时超声造影技术观察肝良性占位病变造影剂灌注特点,探讨其对肝良性占位病变分类诊断的意义。方法选择103例病理证实的肝良性占位病变患者(血管瘤33例,肝硬化增生结节11例,肝细胞腺瘤3例,胆管细胞腺瘤1例,局灶性结节增生6例,局灶性坏死11例,炎性假瘤4例,肝脓肿18例,局灶性脂肪浸润不均匀14例,血管平滑肌脂肪瘤2例),采用超声造影剂SonoVue(2.4 ml团注)和低机械指数(MI 0.09~0.15)反向脉冲谐波造影成像技术进行实时超声造影观察。结果81.8%(27/33)肝血管瘤表现为周边结节状增强及向心性增强模式;83.3%(5/6)局灶性结节增生早期动脉相显示“轮辐状”增强;90.9%(10/11)肝硬化增生结节和100%(14/14)局灶性脂肪浸润不均匀超声造影变化与周边肝组织基本一致;腺瘤及血管平滑肌脂肪瘤动脉相均显示快速整体增强100%(6/6),延迟相83.3%(5/6)显示为等回声或高回声;92.9%(13/14)局灶性坏死和炎性假瘤超声造影病灶内未见增强;94.4%(17/18)肝脓肿造影后病灶内出现大小不等的无回声区呈融合状,与周围肝组织界线清楚。结...

目的利用超声造影剂SonoVue及实时超声造影技术观察肝良性占位病变造影剂灌注特点,探讨其对肝良性占位病变分类诊断的意义。方法选择103例病理证实的肝良性占位病变患者(血管瘤33例,肝硬化增生结节11例,肝细胞腺瘤3例,胆管细胞腺瘤1例,局灶性结节增生6例,局灶性坏死11例,炎性假瘤4例,肝脓肿18例,局灶性脂肪浸润不均匀14例,血管平滑肌脂肪瘤2例),采用超声造影剂SonoVue(2.4 ml团注)和低机械指数(MI 0.09~0.15)反向脉冲谐波造影成像技术进行实时超声造影观察。结果81.8%(27/33)肝血管瘤表现为周边结节状增强及向心性增强模式;83.3%(5/6)局灶性结节增生早期动脉相显示“轮辐状”增强;90.9%(10/11)肝硬化增生结节和100%(14/14)局灶性脂肪浸润不均匀超声造影变化与周边肝组织基本一致;腺瘤及血管平滑肌脂肪瘤动脉相均显示快速整体增强100%(6/6),延迟相83.3%(5/6)显示为等回声或高回声;92.9%(13/14)局灶性坏死和炎性假瘤超声造影病灶内未见增强;94.4%(17/18)肝脓肿造影后病灶内出现大小不等的无回声区呈融合状,与周围肝组织界线清楚。结论低机械指数反向脉冲谐波实时超声造影可准确显示大多数肝良性占位病灶的不同灌注特点,对分类诊断具有重要价值。

Objective To investigate the application of SonoVue contrast-enhanced ultrasound and second harmonic imaging in benign focal hepatic lesions.Methods SonoVue was injected by bolus via peripheral vein of thirty patients with benign focal hepatic lesions.The technique of contrast-enhanced ultrasound and second harmonic imaging were used.The enhancement features of lesions were observed after injection of SonoVue.Results All hemangiomas revealed hyper-enhancement during arterial phase and 20(87%)of them...

Objective To investigate the application of SonoVue contrast-enhanced ultrasound and second harmonic imaging in benign focal hepatic lesions.Methods SonoVue was injected by bolus via peripheral vein of thirty patients with benign focal hepatic lesions.The technique of contrast-enhanced ultrasound and second harmonic imaging were used.The enhancement features of lesions were observed after injection of SonoVue.Results All hemangiomas revealed hyper-enhancement during arterial phase and 20(87%)of them showed periphery -to-center enhancement pattern,2(8.7%)showed center-to-periphery enhancement pattern,1(4.3%)revealed homogeneous enhancement pattern.20 lesions showed hyper-enhancement,2 showed iso- enhancement and 1 revealed hypo- enhancement at portal phase and late phase;2 focal nudolar hyperplasias showed center- to -periphery,central spoke wheel-shaped enhancement pattern during arterial phase.In the portal phase and late phase the lesion revealed iso-enhancement; 3 liver focal fatty sparing lesions had no enhancement in arterial phase.In the portal phase and late phase 3 lesions showed iso- enhancement; 2 hepatic abscesses showed periphery non-enhancement in arterial phase.In late phase 2 lesions showed internal hypo-enhancement and no enhancement.Conclusion The SonoVue contrast-enhanced ultrasound and second harmonic imaging reveals dynamic enhancement features of benign focal hepatic lesions,which is helpful to the diagnosis and differential diagnosis.

目的探讨超声造影在肝良性占位病变诊断中的应用。方法30例肝良性占位病变患者经肘部静脉团注SonoVue。采用超声造影二次谐波成像技术,实时观察注射造影剂后病灶增强特征。结果经超声造影后,23个肝血管瘤动脉相均呈高回声增强,20个(87%)表现为周边向心型,2个(8.7%)为中央扩散型,1个(4.3%)为整体型增强特征,20个病灶在门脉相和延迟相仍为高回声增强,2个病灶渐变为等回声增强,1个病灶渐变为低回声增强。2个肝局灶性结节增生病灶在动脉相均呈中央扩散型增强,表现为轮辐状,门脉相及延迟相呈等回声增强。3个肝局部脂肪缺失病灶均显示动脉相无增强,门脉相及延迟相呈等回声。2个肝脓肿病灶动脉相周边无增强,延迟相病灶内呈低回声增强及无增强。结论SonoVue超声造影二次谐波成像技术能动态显示病灶增强特征,有助于肝良性占位病变的诊断及鉴别诊断。

 
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