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   nateglinide tablets 的翻译结果: 查询用时:0.225秒
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nateglinide tablets
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  本片
     Objective:To screen formulations,optimize preparing technics and study on quality control of Nateglinide tablets.
     目的:筛选那格列奈片的处方、优化工艺,并对本片进行质量研究。
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     Results:A reasonable formulation and feasible technics were found,the HPLC method established were sensitive,reliable and simple with good reproductivity,and the quality of Nateglinide tablets were under control very well.
     结果:所选处方合理、工艺可行,HPLC方法灵敏、可靠、重复性好、操作简单,能够很好地控制本片的质量。
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  “nateglinide tablets”译为未确定词的双语例句
     Method for Dissolution Determination of Nateglinide Tablets in Vitro
     那格列奈片溶出度测定方法
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     To develop a method for dissolution determination of nateglinide tablets in vitro, the dissolution was determinedwith paddle method (50 r·min~1) in 500 mL pH6 .8 phosphate buffer.
     建立了那格列奈片的体外溶出度测定方法,以pH6.8磷酸缓冲液 500 mL为溶出介质,浆法,50 r/min;
短句来源
     Study of determination method on dissolution of nateglinide tablets
     纳格列奈片溶出度测定方法的研究
短句来源
     Preparation study on Nateglinide tablets
     那格列奈片的制剂学研究
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     Study of the stability of nateglinide tablets
     那格列奈片的稳定性研究
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  相似匹配句对
     Dissolution study of tablets of nateglinide
     那格列奈片的溶出度考察
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     Study of the stability of nateglinide tablets
     那格列奈片的稳定性研究
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     Synthesis of Nateglinide
     那格列奈H晶型的合成
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     Aminoglutethimide Tablets
     治疗乳腺癌及皮质醇增多症特效药——氨鲁米特片
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     Meptin Tablets
     美喘清片
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AIM The purpose is to establish innovational identification method of IR (eliminated method) for detection of the crystal form of nateglinide in preparations. METHODS The IR spectrum by spectra subtraction techniques is obtained by subtracting IR spectrum after adding small volume of solvent to eliminate nateglinide from the spectrum of nateglinide tablets′ KBr disk to identify the crystal form of nateglinide. CONCLUSION\ The method (eliminated method) is useful in identification of the nateglinide...

AIM The purpose is to establish innovational identification method of IR (eliminated method) for detection of the crystal form of nateglinide in preparations. METHODS The IR spectrum by spectra subtraction techniques is obtained by subtracting IR spectrum after adding small volume of solvent to eliminate nateglinide from the spectrum of nateglinide tablets′ KBr disk to identify the crystal form of nateglinide. CONCLUSION\ The method (eliminated method) is useful in identification of the nateglinide crystal form in preparation.

目的 :建立一种新的红外光谱方法——消去法 ,以鉴别那格列奈片剂中的晶型。方法 :按常规方法测定那格列奈制剂经溴化钾压片的红外光谱 ,在线原位再次测定除去那格列奈后的同一溴化钾片的红外光谱 ,以差谱技术得出两光谱之差 ,并以晶型的特征峰加以鉴别。结论 :用于制剂中的那格列奈 B晶型或 H晶型的判断。

OBJECTIVE To establish an HPLC method for determination of nateglinide and impurities in nateglinide tablets. METHODS Reversed-phase chromatographic separation was carried out on a Shim-Pack CLC-ODS column(150 mm×6.0 mm) e-quilibrated with an eluent mixture constituted by CH3OH-pH6.6, 0.02 mol·L-1 phosphate buffer (75:25). The detection was performed using ultraviolet detector at 210 nm. The effect of the type of mobile phase on separation of nateglinide and impurities in tablets was examined....

OBJECTIVE To establish an HPLC method for determination of nateglinide and impurities in nateglinide tablets. METHODS Reversed-phase chromatographic separation was carried out on a Shim-Pack CLC-ODS column(150 mm×6.0 mm) e-quilibrated with an eluent mixture constituted by CH3OH-pH6.6, 0.02 mol·L-1 phosphate buffer (75:25). The detection was performed using ultraviolet detector at 210 nm. The effect of the type of mobile phase on separation of nateglinide and impurities in tablets was examined. The quantitative determination of nateglinide was performed with external standard method and the impurity limitation using area normalization method. RESULTS Nateglinide and impurities in tablets were separated completely under optimum conditions and no interference from excipients was found. Linear responses were observed for nateglinide concentration ranging from 5.1 to 101.0 mg·L-1' and the limit of quantification was 0.2 mg·L-1. Assay precision expressed as RSD was less than 1.7% and the recoveries for nateglinide were in the range of 99.4% to 100.4% .CONCLUSIONS The proposed method is simple, accurate, reproducible, and highly selective. It is recommended that this method be used for the quality control, stability study and validity term test of nateglinide tablets.

目的:建立那格列奈片中主药那格列奈及杂质的高效液相色谱测定方法。方法:采用Shim-Pack CLC-ODS(150mm×6.0mm)色谱柱,甲醇-0.02mol.L~(-1)磷酸盐缓冲液(pH6.6)(75:25)作流动相,检测波长210nm,含量测定采用外标法, 杂质检查采用面积归一化法。考察了不同流动相下那格列奈的色谱行为及其与杂质的分离情况。结果:在优化的色谱条件下,片剂辅料不干扰测定,有关杂质与主药那格列奈分离良好,那格列奈线性范围5.1~101.0 mg·L~(-1),最低检测限0.2 mg·L~(-1),含量测定的回收率99.4%~100.4%,RSD<1.7%。结论:此法简便,准确,专属性强,重现性好,可用于那格列奈片的质量控制、稳定性考察和有效期预测。

Objective:To provide the determination method of dissolution in nateglinide tablets pharmacy research.Methods:The oar method for dissolution test in Chinese pharmacopoeia 2000 edition was consulted.Results:The dissolution rate of nateglinide tablets in 7 minutes was more than 80%,with a recovery rate of (99.54±1.43)% and good linearity in a range of 250~1 250μg·mL -1 .Conclusion:The method was suitable for the dissolution test of nateglinide tablets with simple operation and accurate consequence,and...

Objective:To provide the determination method of dissolution in nateglinide tablets pharmacy research.Methods:The oar method for dissolution test in Chinese pharmacopoeia 2000 edition was consulted.Results:The dissolution rate of nateglinide tablets in 7 minutes was more than 80%,with a recovery rate of (99.54±1.43)% and good linearity in a range of 250~1 250μg·mL -1 .Conclusion:The method was suitable for the dissolution test of nateglinide tablets with simple operation and accurate consequence,and the formulation of nateglinide tablets was rational. [

目的 :为仿制纳格列奈片提供片剂制剂学研究的溶出度测定方法。方法 :参照中华人民共和国药典2 0 0 0年版溶出度测定桨法测定其溶出量。结果 :纳格列奈片 7min溶出量在 80 %以上 ,回收率为 (99.5 4± 1.4 3) % ,在 2 5 0~ 12 5 0 μg·mL-1范围内线性关系良好。结论 :该法操作简单 ,结果准确 ,可以作为纳格列奈片的溶出度测定方法 ,同时 ,通过对纳格列奈片溶出度的测定 ,表明纳格列奈片处方设计合理。

 
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