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oral antidiabetic
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  口服降糖
     An Analysis of the Use of Oral Antidiabetic Drugs in Guangzhou in the Years of 1999 to 2002
     1999~2002年广州市部分医院口服降糖药使用分析
短句来源
     Methods Selecting 32 patients with newly diagnosed T2DM(NDM group)and 64 T2DM patients with failure to oral antidiabetic therapy(ODM group),which were treated by insulin pump,having no significant difference of the level of blood glucose,body mass index(BMI),age,proportion of sex between NDM group and ODM group.
     方法选择32例初诊的T2DM患者(NDM组)和64例口服降糖药效果差的T2DM患者(ODM组),两组血糖水平、体重指数(BMI)、年龄、性别构成等均匹配,均给予胰岛素泵强化治疗。
短句来源
     Clinical study of the combined application of the oral antidiabetic drugs in treating type 2 diabetes mellitus
     口服降糖药物联合应用治疗2型糖尿病患者的临床研究
短句来源
     Methods Choose 116 cases T2DM which are newly diagnosed or poorly controlled with oral antidiabetic drugs. They are randomly divided into (insulin aspart 30/70) trial group 60 cases and (biphasic human insulin 30/70) control group 56 cases. To observe the changes of blood glucose levels in various periods.
     方法选初诊或单用口服降糖药物治疗血糖控制不佳的2型糖尿病患者116例,随机分为2组:预混门冬氨酸胰岛素30/70(治疗组)60例,精蛋白生物合成人胰岛素30/70(对照组)56例,观察各时段血糖变化。
短句来源
     The Curative Effect of Insulin Combined with Oral Antidiabetic Agents on Type 2 Diabetes
     胰岛素与口服降糖药联合治疗2型糖尿病疗效观察
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  “oral antidiabetic”译为未确定词的双语例句
     Analysis of the use of the oral antidiabetic agents in our hospital from 2001 to 2004
     我院2001~2004年口服抗糖尿病药物应用分析
短句来源
     Results Sum of money for drug consumption of the oral antidiabetic agents in our hospital in 2004 was 3.58 times of those in 2001,DDDs in 2004 was 2.22times of that in 2001.The sum of money of Acarbose,Glipizide,Gliclazide,Gliquidone and Metformin Hydrochloride was larger in clinical application.
     结果我院口服抗糖尿病药物用药金额2004年是2001年的3.58倍,用药频率2004年是2001年的2.22倍,以阿卡波糖、格列吡嗪、格列齐特、格列喹酮和盐酸二甲双胍的临床使用为最多。
短句来源
     Results:In the recent 3 years, the DDDs ratios of domestic insulin preparations to those produced by joint ventures or imported were 1∶1.10, 1∶1.68 and 1∶2.39, respectively. The annual DDDs growth rate of oral antidiabetic drugs in 1999 and 2000 were 23.29% and 40.06%, respectively.
     结果 :3年来胰岛素制剂国产与合资及进口产品的DDDs之比分别为 1∶1.10 ,1∶1.68,1∶2 .3 9,口服降血糖药的金额年增长率分别为 2 3 .2 9%及 40 .0 6%。
短句来源
     Conclusion The oral antidiabetic agents play an important role in the clinical treatment of the type 2 diabetes.
     结论口服抗糖尿病药在2型糖尿病的临床治疗中占有重要地位。
短句来源
     Methods To analyze and sum up the use of the oral antidiabetic agents in our hospital from 2001 to 2004 by using the methods of DDDs analysis and ranking of amount of money.
     方法采用金额排序法和频度分析法对我院2001~2004年口服抗糖尿病药物应用情况进行统计分析。
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  相似匹配句对
     Progress and research in pharmacogenetics of oral antidiabetic drugs
     口服降糖药的遗传药理学研究进展
短句来源
     Pharmacological Research of Compound Antidiabetic Oral Liquid
     复方降糖口服液的药理研究
短句来源
     Oral Cnglish
     英语口语
短句来源
     Oral English
     英语口语
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     Antidiabetic effects of Vanadium
     钒类化合物的抗糖尿病作用
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  oral antidiabetic
Interaction between diazepam and oral antidiabetic agents on serum glucose, insulin and chromium levels in rats
      
We investigated the efficacy and safety of adding once-daily insulin glargine to patients' current oral antidiabetic drugs (OAD) regimen, compared to increasing the OAD doses.
      
Fifty patients with type 2 diabetes who had been initially treated with oral antidiabetic agents without a satisfactory response were included in this study.
      
The aim of this study was to analyse the effect of the new oral antidiabetic drug repaglinide on antioxidant factors and lipid peroxidation in tissues of alloxan-induced diabetic rabbits after 4 and 8 weeks treatment.
      
Before initiating insulin therapy, clinicians often wait until oral antidiabetic agents fail to adequately reduce glycosylated hemoglobin (A1C) levels and control hyperglycemia in patients with type 2 diabetes.
      
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This artical is a clinical observation report of 56 cases of type Ⅱ diabetes mellitus.treated by comprehensive therapy of propaganda and education,nutrition and diet therapy ,exercise therapy,oral antidiabetic drug and Huitang crenotherapy. The results showed that fasting glucose was significantly decreased and clinical symptom was evidently improved by the therapy. (According to statistic process,P<0. 01,there is a remarkable difference.) Author analyses Huitang crenotherapy plays a very important role...

This artical is a clinical observation report of 56 cases of type Ⅱ diabetes mellitus.treated by comprehensive therapy of propaganda and education,nutrition and diet therapy ,exercise therapy,oral antidiabetic drug and Huitang crenotherapy. The results showed that fasting glucose was significantly decreased and clinical symptom was evidently improved by the therapy. (According to statistic process,P<0. 01,there is a remarkable difference.) Author analyses Huitang crenotherapy plays a very important role in comprehensive therapy and suggested that radon spring or/and hydrogen sulfide spring crenotherapy be a convalescent and rehabilitation ideal therapy of type Ⅱ diabetes mellitus.

本文是用宣传教育、饮食疗法、运动疗法、口服降糖药物和灰汤矿泉疗法等综合疗法治疗Ⅱ型糖尿病56例的一篇临床观察报告。结果表明:该疗法具有降低空腹血糖,改善临床症状的显著疗效(经统计学处理,P<0.01,有显著性差异)。通过分析灰汤矿泉疗法在综合疗法中的重要作用,提示氡泉或/和硫化氢泉等矿泉疗法是Ⅱ型糖尿病疗养和康复的一种理想疗法。

Objective To determine the effects of glycemic control on thirst and ADH response to plasma hyperosmolality in type 2 diabetes with thirst perception defect and low ADH reserve. Methods Eight poorly controlled type 2 diabetics (HbA 1c 12 56±1 05%, ranged from 11 5%~14 5%) with thirst perception defect and low ADH reserve were studied by intravenous infusion of 5% sodium chloride at the rate of 0 06ml·kg -1 /min before and twelve months after improving glycemic control. The levels of ADH of plasma...

Objective To determine the effects of glycemic control on thirst and ADH response to plasma hyperosmolality in type 2 diabetes with thirst perception defect and low ADH reserve. Methods Eight poorly controlled type 2 diabetics (HbA 1c 12 56±1 05%, ranged from 11 5%~14 5%) with thirst perception defect and low ADH reserve were studied by intravenous infusion of 5% sodium chloride at the rate of 0 06ml·kg -1 /min before and twelve months after improving glycemic control. The levels of ADH of plasma and thirst scales were measured at the levels of normal and hyper osmolalities of plasma. The ADH level of plasma was determined by radioimmunoassay. Thirst intensity was estimated by means of a linear visual analogue scale.Results Significant improvement in glycemic control (before vs. after: mean HbA 1c 12 56±1 05% vs. 6 94±0 93%,P<0 001) was achieved without severe hypoglycemia during the twelve month period of treatment with oral antidiabetic drugs (glibenclamide or glipizide and metformin) and/or rapid acting insulin in eight cases of type 2 diabetes. There were no differences of thirst scales and plasma ADH levels at the level of normal osmolality of plasma (near 280 mOsm/kgH 2O, ranged from 275 mOsm/kgH 2O to 285 mOsm/kgH 2O) before and twelve months after improving glycemic control in eight patients. As compared with not improving glycemic control at the level of plasma hyperosmolality (310 mOsm/kgH 2O), after improving glycemic control, plasma ADH levels were significantly increased (before vs. after: 5 63±0 81ng/L vs.7 13±0 59ng/L,P<0 001). After improving glycemic control, thirsty scales of five out of eight patients were significantly increased at the level of plasma osmolality of 310 mOsm/kgH 2O (before vs. after: 4 50±0 58cm vs. 5 76±0 77cm,P<0 001), but thirsty scales of three out of eight patients showed no change (before vs. after: 4 47±1 29cm vs. 4 20±0 92cm,P>0 05).Conclusion Improving glycemic control increases ADH secretion and thirsty scales in poorly controlled type 2 diabetes patients with thirst perception defect and low ADH reserve.

目的 探讨血糖控制对 2型糖尿病病人渴感和抗利尿激素 (ADH)反应性的影响。方法 测定伴渴感减退及ADH分泌不足的 8例血糖控制不良 (Hb A1 c11 5 %~ 14 5 % )的 2型糖尿病病人 ,在血糖满意控制 (Hb A1 c5 9%~8 4 % ) 12个月前后血浆渗透压 (血渗 )正常 (2 75~ 2 85 m Osm kg H2 O)和增高 (3 10 m Osm kg H2 O)时渴感程度及血浆ADH水平 ,并进行自身前后比较。渴感程度采用视觉量表评估 ,ADH采用放免法测定。结果 血糖满意控制 12个月对血渗正常时渴感及血浆 ADH水平无明显影响。对血渗增高时渴感的影响不一 ,8例中有 5例渴感增强 (前∶后 ,4 5 0±0 5 8cm vs5 76± 0 77cm,P<0 0 0 1) ,3例渴感无明显变化 (前∶后 ,4 2 0± 0 92 cm vs4 4 7± 1 2 9cm,P>0 0 5 ) ;血渗增高时血浆 ADH8例均明显增高 (前∶后 ,5 63± 0 81ng L vs7 13± 0 5 9ng L,P <0 0 0 1)。结论 血糖...

目的 探讨血糖控制对 2型糖尿病病人渴感和抗利尿激素 (ADH)反应性的影响。方法 测定伴渴感减退及ADH分泌不足的 8例血糖控制不良 (Hb A1 c11 5 %~ 14 5 % )的 2型糖尿病病人 ,在血糖满意控制 (Hb A1 c5 9%~8 4 % ) 12个月前后血浆渗透压 (血渗 )正常 (2 75~ 2 85 m Osm kg H2 O)和增高 (3 10 m Osm kg H2 O)时渴感程度及血浆ADH水平 ,并进行自身前后比较。渴感程度采用视觉量表评估 ,ADH采用放免法测定。结果 血糖满意控制 12个月对血渗正常时渴感及血浆 ADH水平无明显影响。对血渗增高时渴感的影响不一 ,8例中有 5例渴感增强 (前∶后 ,4 5 0±0 5 8cm vs5 76± 0 77cm,P<0 0 0 1) ,3例渴感无明显变化 (前∶后 ,4 2 0± 0 92 cm vs4 4 7± 1 2 9cm,P>0 0 5 ) ;血渗增高时血浆 ADH8例均明显增高 (前∶后 ,5 63± 0 81ng L vs7 13± 0 5 9ng L,P <0 0 0 1)。结论 血糖满意控制 12个月可明显改善全部 8例 ADH及部分病例渴感对血浆高渗的反应。提示长期高血糖高血渗是致 ADH分泌不足及渴感减退的原因之一。

N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-Phenylalanine, a novel oral antidiabetic agent,is a nonsulfonylurea insulinotropic agent. It inhibited the ATP-sensitive K+channel and increased cytosolic free Ca2+ concentration in pancreatic:A-cells. Oral administration of nateglinide produced a rapid onset and short duration of hypoglicemic action with an acute increase in plasma insulin concentration. In thes paper, we reviewed its mechanism, pharmacokinetics, clinical treatment.

那格列奈,N-(反式-4-异两基环己烷羰基)-D-苯丙氨酸为一新型餐时血糖调节剂,能抑制胰腺β-细胞中ATP敏感的K+通道,增加细胞内Ca2+浓度,使血浆内胰岛素水平升高,具有起效快、作用时间短的特点。本文主要对那格列奈的作用机理、药代动力学、临床疗效进行了介绍。

 
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