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serum hbeag
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  血清e抗原
     Results:Above factors were comparable between two groups. The recurrence rates of 31 patients with ELISA for detection of serum HBeAg and 38 with time resolved fluoroimmunoassay was 32 3% and 10 5% respectively,which was significantly different( χ 2 =4 985, P =0 026).
     结果 :两组患者上述因素具有可比性 ,以ELISA法检测血清e抗原者追踪期复发率为 3 2 3 % ,应用时间分辨免疫荧光法者为 10 .5 % ,两者有统计学差异 (χ2 =4 .985 ,P =0 .0 2 6)。
短句来源
     RELATIONSHIP OF SERUM HBeAg/ANTI-HBe SYSTEM TO THE SEVERITY OF DISEASE AND ITS PROGNOSIS IN PATIENTS WITH CHRONIC HEPATITIS B
     慢性乙型肝炎患者血清e抗原抗体系统与病情和预后关系的探讨
短句来源
     Relationship of serum HBeAg/Anti-HBe system to the severity of disease and the prognosis in 114 patients with chronic hepatitis B was analyzed.
     本文分析了114例慢性乙型肝炎(CHB)患者血清e抗原抗体系统与病情和预后的关系。 结果表明,HBeAg阳性者大多数表现为慢性迁延性肝炎(CPH),而HBeAg(-)抗HBe(+)者较多表现为慢性活动性肝炎(CAH)、肝硬化、慢重肝或肝癌。
短句来源
     Objective:To analyze the effects of different serum HBeAg detction methods on the therapy effect assessment of anti HBV treatment and on follow up recurrence rates.
     目的 :分析血清e抗原水平不同监测方法可能对抗HBV治疗中疗效评价和追踪期复发率评价的影响。
短句来源
     Methods:In a follow up study of 69 chronic hepatitis B patients who were justified as “complete responsive” to α Interferon or Lamivudine in anti HBV therapy,after withdrawal of medicine,serum HBeAg from 31 patients was detected with ELISA and 38 with time resolved fluoroimmunoassay. Recurrence rates between two groups were compared. Comparability was analyzed in gender ratio,average age,ALT and HBV DNA level before therapy and in treatment modality.
     方法 :对 69例α干扰素 (IFN)或拉米夫定 (LAM )抗HBV治疗评价为“完全应答”的慢性乙型肝炎患者追踪观察 ,比较 3 1例以ELISA法监测血清e抗原水平变化的患者和 3 8例应用时间分辨免疫荧光法的患者完全停药后的复发率 ,同时进行性别比、平均年龄、开始治疗时的ALT和HBVDNA水平及治疗方案的可比性分析。
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  “serum hbeag”译为未确定词的双语例句
     The elevation of CD8+/CD28+CD45RO+ subtype was probably related to the progress of chronic hepatitis B and the serum HBeAg conversion.
     CD8+/CD45RO+/CD28+亚型淋巴细胞数的升高与慢性乙肝的病情进展及血清HBeAg转换有关。
短句来源
     Analysis of correlation between quantitative detection of serum HBeAg and HBsAg by ECLIA and the content of HBV DNA
     ECLIA定量检测HBsAg及HBeAg与HBV-DNA相关分析
短句来源
     The conversion rate of serum HBeAg in patients with genotype B (41case) virus infection was significantly higher than those with genotype C (8 cases) infection ( 68.3% vs 40%, P< 0.05 ).
     HBeAg/HBeAb血清转换率B型41例(68.3%)高于C型8例(40%)(P<0.05)。
短句来源
     Results indicate that in 77 serum HBeAg positive cases, 74(96.1%) were Pre S2 positive.
     结果表明:HBeAg阳性77例,Pre S_2阳性74例(96.1%)。
短句来源
     Methods:The expressions of serum HBeAg and Pre-S1Ag in 188 cases of different HBV-DNA samples(HBV-DNA by FQ-PCR) were detected,and the comparative analysis was performed.
     方法:采用ELISA法对188例不同HBV-DNA含量(荧光定量PCR检测)的标本进行HBeAg、Pre-S1Ag检测,并作比较分析。
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  相似匹配句对
     Phyllanthus amarus on serum HBeAg.
     草药叶下珠对清除血清HBeAg有效。
短句来源
     The serum C.
     ELISA法检测血清C .
短句来源
     Simultaneously, HBeAg and HBcAb in serum were examined by ELISA.
     结果:血清NBeAg阳性率27%(10/37),血清HBV-DNA检出率57.1%(20/35),两者有显著性差异。
短句来源
     HBsAg,HBeAg;
     HBsAg(+)、HBeAg(+);
短句来源
     For serum TG;
     (2)血清丙二醛以棕桐油组最低,猪油组最高。
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  serum hbeag
In 88% of patients with serum HBV-DNA,irrespective of the serum HBeAg status, chronic activehepatitis was seen.
      
Loss of serum markers of activereplication appeared less durable in the Asian responders compared to the Caucasians withreappearance of serum HBeAg in two (25%) of eight of theformer but only one (17%) of the latter group.
      
Pathogenesis of chronic liver disease in patients with chronic hepatitis B virus infection without serum HBeAg
      
In cases of CAH with serum HBeAg positive, HLA-A,B,C, antigens and HBV antigens simultaneously demonstrated on the same hepatocytes.
      
Only the nuclear localization of HBcAg in immunohistochemical studies was a reliable prognostic indicator of transition to chronicity; absence or presence of serum HBeAg was of no help in predicting the outcome of acute HBsAg hepatitis.
      
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The serum, semen, saliva and urine in patients infected with HBV were assayed for HBV-DNA by direct spot hybridization technique and for DNA-P(RIA technique). It was found that the serum HBV-DNA would always be postive if re-rum DNA-P has been positive and it would also be positive, whenever the semen, saliva or urine HBV-DNA was positive. When the serum HBV-DNA was negative, HBV-DNA would not be detected in saliva or urine too. It was further found that the serum, semen, saliva or urine...

The serum, semen, saliva and urine in patients infected with HBV were assayed for HBV-DNA by direct spot hybridization technique and for DNA-P(RIA technique). It was found that the serum HBV-DNA would always be postive if re-rum DNA-P has been positive and it would also be positive, whenever the semen, saliva or urine HBV-DNA was positive. When the serum HBV-DNA was negative, HBV-DNA would not be detected in saliva or urine too. It was further found that the serum, semen, saliva or urine HBV-DNA could be detected not only in the serum HBeAg Positive but also in the HBe Ag negative patients. Conclusions- (1) The blood of HBV infected patients is the most infections as the positive rate of serum HBV-DNA and DNA-P are the highest. (2) Patients with negative HBeAg might also be infections. (3) Saliva might be important in the epidemiology of hepatitis B since in nearly half of the patients HBV-DNA has been detected in saliva. (4) Semen might serve as an infections agent to the patient's mate particularly might cause transmission of the disease to the child.

本文采用斑点杂交法和放射免疫法检测乙肝患者血液、唾液、尿液以及精液中的HBV-DNA和DNA-P。血清中HBV-DNA和DNA-P的阳性检出率基本一致。精液、唾液和尿液中HBV-DNA阳性者,血清中HBV-DNA均阳性。血清中HBV-DNA阴性者,唾液、尿液中均未检出HBV-DNA。血清中HBeAg阳性与否,在血清、精液,唾液、尿液中均能检出HBV-DNA。文章认为:(1)血清中HBV—DNA、DNA-P的检出率最高,传染性较强。(2)血清中HBeAg阴性者,四种体液中亦可检出HBV-DNA,不能排除其传染性。(3)唾液中HBV—DNA的检出率为45.45%,其流行病学意义值得重视。(4)精液中检出HBV-DNA,父系垂直传播也是值得研究的一个问题。

Hepatitis B e-antigen(HBeAg)secreted by genetically engineered L cell was used as antigen in an ELISA test for the detection of hepatitis B e-antibody (anti-HBe) in human sera. Parallel tests of 31 anti-HBe positive sera and 19 anti-HBe negative sera by ELISA using cell-secreted antigen and Abbott anti-HBe EIA kit showed complete agreement of results. The OD 490nm value of the test are reproducible within 8% and a linear line was obtained by plotting OD 490nm against antibody dilutions. The cell supernatant...

Hepatitis B e-antigen(HBeAg)secreted by genetically engineered L cell was used as antigen in an ELISA test for the detection of hepatitis B e-antibody (anti-HBe) in human sera. Parallel tests of 31 anti-HBe positive sera and 19 anti-HBe negative sera by ELISA using cell-secreted antigen and Abbott anti-HBe EIA kit showed complete agreement of results. The OD 490nm value of the test are reproducible within 8% and a linear line was obtained by plotting OD 490nm against antibody dilutions. The cell supernatant may be used without purification, usually at 1:4 dilution. This antigen is non-infectious, cheap and free from spurious reactions due to associated human proteins. Thus it appears to be superior to the human serum HBeAg routinely used in diagnostic kits.

应用乙型肝炎病毒核心抗原基因转化的小鼠L细胞分泌的乙型肝炎病毒e抗原,采用ELISA法与Abbott公司抗-HBe EIA诊断盒平行比较,检测了31份抗-HBe阳性和19份抗-HBe阴性的人血清,结果完全相符。经多次重复试验,本法的OD490nm值的误差不超过8%。OD490nm值与血清稀释度之间呈直线关系。细胞培养液不经纯化即可应用,一般做1:4稀释。细胞分泌的抗原无感染性,价格低廉,不会因结合人血清蛋白而产生非特异性反应。因此比一般诊断盒中所用的人血清HBeAg有很大的优越性。

The serum HBsAg/IgM complexes(HBsAg/IgMc)was determined and observatedin 72 cases of hepatitis B.The results showed that serum HBsAg/IgMc positive wasrespectively present in 42.9% and 66.7% of patients with acute or chronic hepatitisB.However,after the HBsAg/IgMc turned negative,the serum amino-transaminase(SGPT)level of patients with acute hepatitis B decreased,but not in those withchronic hepatitis B(P<0.01).In the correlative analysis patients with acute hepatitiswhich had positive for serum...

The serum HBsAg/IgM complexes(HBsAg/IgMc)was determined and observatedin 72 cases of hepatitis B.The results showed that serum HBsAg/IgMc positive wasrespectively present in 42.9% and 66.7% of patients with acute or chronic hepatitisB.However,after the HBsAg/IgMc turned negative,the serum amino-transaminase(SGPT)level of patients with acute hepatitis B decreased,but not in those withchronic hepatitis B(P<0.01).In the correlative analysis patients with acute hepatitiswhich had positive for serum HBsAg/IgMc mostly were associated with high titerwith serum anti-HBcIgM.When the HBsAg/IgMc negative occured at the early stageof the illness the serum HBeAg decreased,and anti-HBe developed with good prog-nosis.It was suggested that the complexes were an early serologic index in acuteHBV infection,and to helpful for both the prognosis and differentiation betweenacute or chronic HBV infections.

本文对72例乙型肝炎(乙肝)患者动态检测和观察血清 HBsAg/IgM 复合物(HBsAg/IgMc)。结果:急性和慢性乙肝患者入院初期分别有42.9%和66.7%HBsAg/IgMc 阳性。其中,85.7%的急性乙肝患者随血清转氨酶(SGPT)下降而相继 HBsAg/IgMc 阴转。慢性乙肝则表现持续阳性(P<0.01)。经相关分析发现,急性乙肝 HBsAg/IgMc 阳性多伴有高滴度的抗-HBcIgM,并随后者滴度下降而转阴;早期 HBsAg/IgMc 阴转者 HBeAg 多可消失,并相继抗-HBe 阳转,预后良好。表明该复合物是急性 HBV 感染的早期血清学指标之一,并对预后的顶测和急慢性 HBV 感染的鉴别具有临床参考价值。

 
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