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   host genetic 的翻译结果: 查询用时:0.199秒
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感染性疾病及传染病
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host genetic
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  宿主遗传
     Studies on Association between HIV-1 Biological Characteristics and Host Genetic Background with Disease Progression
     HIV-1生物学特性及宿主遗传背景与疾病进展关系的研究
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     Objective To summarize advances on research of helicobacter pylori(Hp) virulence genes and host genetic polymorphisms in development of Hp-associated diseases,provide basis for preventing and controlling Hp-associated diseases.
     目的总结幽门螺杆菌(Hp)毒力基因及宿主遗传多态性对疾病作用的研究进展,为Hp相关疾病的预防和控制提供依据。
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     Conclusion Hp and host genetic polymorphisms result in clinical outcome of Hp infector together.
     结论Hp感染者的临床结局受生物因素Hp、宿主遗传多态性等多种因素的共同作用。
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     The clinical outcomes of hepatitis B virus (HBV) infection are extremely various, and might be associated with host genetic factors, viral factors and environmental factors.
     人类感染乙型肝炎病毒(hepatitis B virus,HBV)后可表现为HBV自限性感染、长期无症状HBV携带等不同结局,并存在明显乙型肝炎家庭集聚性。 其原因除受HBV特征、母婴传播与水平传播、宿主免疫能力等因素影响外,宿主遗传因素也可能起重要作用。
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     Our data may be useful for studies to investigate the role of host genetic factors in SARS pathogenesis,especially for identifying SARS susceptible and/or anti SARS alleles.
     这些SNP的发现 ,为SARS CoV的宿主遗传因素研究 ,特别是发现SARS CoV感染和SARS发病的易感基因或抗病基因 ,提供了遗传标记。
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  “host genetic”译为未确定词的双语例句
     Conclusion mxA promoter-88G/T SNP might be confered to host genetic susceptibility to SARS in Chinese Han population.
     结论mxA基因启动子88位G/T多态性可能与中国汉族人群SARS发病的基因易感性有关。
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     Conclusion TNFA promoter polymorphisms are important host genetic factors affecting the outcomes of HBV infection.
     结论TNFA基因启动子区多态性与HBV感染结局显著关联。
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     Conclusion DQB1*03032 may contribute to resistance against H.pylori infection and the absence of DQB1*0602 may be a host genetic factor for H.pylori-associated gastritis.
     结论 DQB1 0 3 0 3 2对H . pylori感染可能具有抵抗保护作用,DQB1 0 60 2缺乏可能是H .
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     Identification of the Relationship Between the Host Genetic Background and the Rice Blast Pathogenic Lineage by Molecular Markers
     应用分子标记技术鉴证稻瘟病菌宗谱与寄主遗传背景的亲缘关系
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     Objective:The infection and clearance of HBV may be associated with many factor,such as virus itself factor、host genetic factor and immunity factor.
     目的:HBV感染与清除,不同个体的差异可能与多种因素有关,如病毒本身的因素、宿主免疫因素和遗传因素等。
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  相似匹配句对
     The genetic
     用等电聚焦免疫固定技术调查成都地区汉族群体Bf的遗传多态性。
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     Genetic variability of gliadin in Triticum compactum Host.
     密穗小麦(Triticum compactum Host.)醇溶蛋白遗传多样性分析
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     The host bacteria is E.
     文库宿主菌为E.
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     Genetic Algorithm
     遗传算法
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     The genetic linkage group was obviously correlated to the host rice cultivar.
     遗传型与寄主水稻品种存在明显相关性
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  host genetic
Recent studies suggest that a combination of host genetic factors, bacterial virulence factors, and environmental and lifestyle factors determine the severity of gastric damage and the eventual clinical outcome of Helicobacter pylori infection.
      
The interaction of host genetic factors and Helicobacter pylori infection
      
We conclude that scrapie development not only depends on host genetic factors but also requires exogenous factors.
      
Analysis of host genetic control of scrapie-induced obesity
      
Both viral and host genetic factors determine the tissue tropism of influenza viruses in mammals.
      
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The present study was designed to investigate the regulatory effect of Xenopus oocyte cytoplasm on the functional activity of the injected mammalian erythroid nuclei taken from different developmental stages and the tumor cell nuclei from human HeLa and mouse plasmocytoma (Sp 2/0) cell lines. Experimental results demonstrated that: (1) only 1/3 of the injected erythroid nuclei derived from different physiological status survived and - were induced to become enlarged, accompanied by chromatin dispersion, clear...

The present study was designed to investigate the regulatory effect of Xenopus oocyte cytoplasm on the functional activity of the injected mammalian erythroid nuclei taken from different developmental stages and the tumor cell nuclei from human HeLa and mouse plasmocytoma (Sp 2/0) cell lines. Experimental results demonstrated that: (1) only 1/3 of the injected erythroid nuclei derived from different physiological status survived and - were induced to become enlarged, accompanied by chromatin dispersion, clear nucleoplasm, and with the ability of incorporation of~3H-uridine for the synthesis of RNA, while most of the injected nuclei in pyknosis or in late differentiated stage were inactivated, stained black and degenerated steadily; (2) almost all the "injected tumor cell nuclei originally in active division of Sp 2/0 and HeLa survived and were activated by showing nuclei enlarged to about 10 to 200 times with fully chromatin dispersion, concomitant clear nucleoplasm and well developed nuclcoli. The state of activation is much more pronounced than that in erythroid nuclei; (3) isoelectrophoretic analysis of the oocytes with transplanted nuclei showed a dark band at pi 6.28 which is corresponding to a homologous component, but other than hemoglobin from rat bone marrow erythrocytes. It is suggested that the gene activities of the injected nuclei were reprogrammed by the oocyte cytoplasm, globin gene originally activated were closed and oocyte selected to open genes that suitable to host genetic state; (4) when injected into Xenopus oocyte with purified rat globin mRNA polyribosomes, it translated efficiently into hemoglobin. The above mentioned results could be concluded that the Xenopus oocyte provided favorable conditions for the translation of purified mRNA polysomes as well as to regulate or reprogram the expression of gones in the injected nuclei. The regulatory effect is closely related to the initial physiological status and the competence of the injected nuclei themselves responsed to oocyte cytoplasm, i.e. the efficiency is much more prominent in originally active proliferative nuclei than those in late or terminal differentiation.

本文用细胞核微注射技术和分子生物学方法,研究非洲爪蟾卵母细胞对植入的发育不同阶段的哺乳类成红细胞核、体外培养的肿瘤细胞核(Sp 2/0和HeLa细胞)的功能活动调节作用。实验结果表明:1.处于不同生理状态的大鼠成红细胞核注入卵内后,只有部分(约1/3)存活和被激活,出现核膨大、染色质松散、核质清明等被激活的形态特征,且具有并合~3H-尿嘧啶核苷合成RNA的能力。大部分原来处于分化晚期或核固缩状态的成红细胞核,未能被卵母细胞质激活,而呈现深染、浓缩和裂解,或趋于退化消失。2.处于低分化和增殖活跃状态的Sp 2/0和HeLa细胞核植入后,几乎全部被激活,核膨大(体积增大数十倍至二百倍以上),染色质充分松散、核质清明、核仁发达,被激活的程度较成红细胞核更为明显。3.等电聚焦电泳分析表明,植入成红细胞核的卵母细胞,在电泳图上出现了一条等电点(pI)为6.28的条带,与大鼠骨髓成红细胞电泳条带同源物相当,但未能检测到血红蛋白。表明植入核的基因活动状态已为卵质所重排,原来活跃的珠蛋白基因被关闭,而选择性地激活与卵质相适应的基因使之表达。4.将提纯的珠蛋白mRNA多核糖体注入卵母细胞后,可检测到有血红蛋白的合成。上述结果说...

本文用细胞核微注射技术和分子生物学方法,研究非洲爪蟾卵母细胞对植入的发育不同阶段的哺乳类成红细胞核、体外培养的肿瘤细胞核(Sp 2/0和HeLa细胞)的功能活动调节作用。实验结果表明:1.处于不同生理状态的大鼠成红细胞核注入卵内后,只有部分(约1/3)存活和被激活,出现核膨大、染色质松散、核质清明等被激活的形态特征,且具有并合~3H-尿嘧啶核苷合成RNA的能力。大部分原来处于分化晚期或核固缩状态的成红细胞核,未能被卵母细胞质激活,而呈现深染、浓缩和裂解,或趋于退化消失。2.处于低分化和增殖活跃状态的Sp 2/0和HeLa细胞核植入后,几乎全部被激活,核膨大(体积增大数十倍至二百倍以上),染色质充分松散、核质清明、核仁发达,被激活的程度较成红细胞核更为明显。3.等电聚焦电泳分析表明,植入成红细胞核的卵母细胞,在电泳图上出现了一条等电点(pI)为6.28的条带,与大鼠骨髓成红细胞电泳条带同源物相当,但未能检测到血红蛋白。表明植入核的基因活动状态已为卵质所重排,原来活跃的珠蛋白基因被关闭,而选择性地激活与卵质相适应的基因使之表达。4.将提纯的珠蛋白mRNA多核糖体注入卵母细胞后,可检测到有血红蛋白的合成。上述结果说明,卵质具备对多核糖体mRNA忠实翻译和调节或重编排植入核基因表达的条件。调节作用因不同结构水平而异。与植入核原来的生理状态及对卵质的感应能力密切相关,原来处于活跃增殖状态的植入核受调节的程度,较终末分化的细胞核显著得多。

The polymorphism restriction fragment length of (RFLPs) among 112 rice blast pathogen lsolates (Magnaporthe grisea ) collected from the four rice ecological growth regions (RER) in Guangdong was analyzed by dispersed repetitive sequence probe MGR586 and restriction endonuclease EcoRI combination. The total sum of 112 Pathogens was clustered into 15 genetic lineages according to their band patterns in the RFLPs haplotype.Lineage I and lineage 2 may be designated as the predomlnant lineages according to their...

The polymorphism restriction fragment length of (RFLPs) among 112 rice blast pathogen lsolates (Magnaporthe grisea ) collected from the four rice ecological growth regions (RER) in Guangdong was analyzed by dispersed repetitive sequence probe MGR586 and restriction endonuclease EcoRI combination. The total sum of 112 Pathogens was clustered into 15 genetic lineages according to their band patterns in the RFLPs haplotype.Lineage I and lineage 2 may be designated as the predomlnant lineages according to their widely distribution overall the four rice ecological growth region in the province with the total sum 85 out of 112, The genetic diversity value of the pathogen population for testing was 0. 64.Diversity of blast pathogens was closely correlated with the host genetic background,and the relationship between genetic lineage and pathogenicity spectrum was also discussed.

利用散布性重复序列(dispersedrepetitivesequence)MGR586探针与EcoRI组合,分析了采自广东省4个自然生态稻作区的112个猪瘟病菌株的限制性片断长度多态性(RFLPs),根据彼此间RFLPs单型(haplotype)的带型位置相似率达80%为度,把这些菌株划分为15个遗传宗谱(geneticlineage),其中宗谱1及宗谱2占总数的78.58%,遍布全省各地,是优势宗谱。供测菌株的RFLPs单型的多样性显示出我省稻瘟病菌的群体结构呈现多样性。参试菌株的群体遗传多样性值为0.64。谱型分析表明,我省多数病原型是杂合群体。在分子水平上划分的病菌宗谱与寄生品种的遗传背景有密切关系。研究结果也初步建立了病菌宗谱与用以鉴别寄主反应划分的生理小种致病谱型的相互关系。

Fifteen genetic lineages of the rice blast pathogen(M. grisea)were clustered based on their band paterns in the RFLPs haplotype measured by the RFLP among 112 pathogen collected from four rice ecological growth regions in Guangdong province. The diversity of blast pathogens in DNA fingerprinting were closely related with the host genetic background of the host based on their affinity and adaptability in V×I interaction to blast. Experimental results disclosed the phenomina of short life cycle...

Fifteen genetic lineages of the rice blast pathogen(M. grisea)were clustered based on their band paterns in the RFLPs haplotype measured by the RFLP among 112 pathogen collected from four rice ecological growth regions in Guangdong province. The diversity of blast pathogens in DNA fingerprinting were closely related with the host genetic background of the host based on their affinity and adaptability in V×I interaction to blast. Experimental results disclosed the phenomina of short life cycle of blast resistance in most of conventional rice cultivars and hybrid rice cultivars developed by Guangdong even though in South China were in short of durable resistant sources. Furthermore, the way for improvement of breeding program in blast disease resistance was also discussed and suggested.

用散布性重复序列MGR586 探针与EcoRI组合,分析广东省稻区的112 个稻瘟病菌株( M. grisea )的限制性片段长度多态性(RFLPs),根据带型相似性大于80% 为度划分为15个遗传宗谱(genetic lineage)。这些在分子水平上划分的宗谱与寄主品种的遗传背景关系密切。由于广东省(包括华南稻区)大多数育成的常规稻品种和杂交稻组合在遗传背景上与GDL1 及GDL2 两个优势病菌宗谱寄主具有相似的共进化同缘宗亲关系, 致使品种的抗性水平不高,抗性周期短暂。从而提出了选择异源供体, 开展多元化育种的方向及途径。

 
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