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   clinical detoxification 的翻译结果: 查询用时:0.177秒
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clinical detoxification
相关语句
  临床脱毒
     There was no difference in the fluctuating craving levels among the groups of one month, two months, three months, and over three months after clinical detoxification(F=1.345,P=0.259).
     临床脱毒后 ,一个月、二个月、三个月及三个月以上 ,渴求分值的变化没有显著性(F=1.345,P=0.259)。
短句来源
     Objective: To investigate drug craving in heroin addicts in drug-free condition after clinical detoxification in China.
     目的··:观察国内临床脱毒后未染毒的海洛因依赖者的渴求状况。
短句来源
     Conclusion: Drug craving lasts long time after clinical detoxification.
     结论·· :部分海洛因依赖者临床脱毒后 ,药物渴求持续存在
短句来源
  “clinical detoxification”译为未确定词的双语例句
     PHARMACODYNAMIC RESEARCH OF DIHYDROETORPHINE HYDROCHLORIDE (DHE) IN CLINICAL DETOXIFICATION OF HEROIN ADDICTS
     二氢埃托啡临床治疗海洛因成瘾者的药效学研究
短句来源
     THERAPEUTIC COMMUNITY IN THE CLINICAL DETOXIFICATION OF HEROIN ADDICTS
     在海洛因依赖者的脱毒治疗中应用治疗社区技术
短句来源
     Conclusion:THPBs could inhibit abstinence syndroms in morphine-dependent mice and rats,which suggested that it may be useful in clinical detoxification.
     结论··:THPBs可缓解吗啡依赖小鼠和大鼠戒断症状,可能具有临床应用价值。
短句来源
  相似匹配句对
     It has been used to detumescence、 detoxification、 pesticides in clinical.
     具有消肿、解毒、杀虫等功效。
短句来源
     THERAPEUTIC COMMUNITY IN THE CLINICAL DETOXIFICATION OF HEROIN ADDICTS
     在海洛因依赖者的脱毒治疗中应用治疗社区技术
短句来源
     Results of clinical
     试验结果表明EDM的临床总有效率高达94.3%,
短句来源
     The clinical study.
     临床研究部分。
短句来源
     Detoxification for Rapeseed Meal
     菜籽的脱毒方法
短句来源
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  clinical detoxification
The interaction between luteolin and GHB may offer a potential clinical detoxification strategy to treat GHB overdoses.
      
Finally, the effectiveness of depot buprenorphine in providing clinical detoxification appears promising.
      


This paper reported pharmacodynamics of DHE in clinical detoxification of 38 heroinaddicts. The correlation coefficient is 0.8026 between CINA (Clinical Institute Narcotic Assessment) Scalescore and the maintenance DHE dose sublingully. The maintenance dose used in the treatment of individualpatients was regressed on CINA score. The simple regression equeation was: DHE dose(microgram / hour)=1.6309 CINA Score + 6.4554. Further analysis indicated that the inclusion of the exponential termimproved...

This paper reported pharmacodynamics of DHE in clinical detoxification of 38 heroinaddicts. The correlation coefficient is 0.8026 between CINA (Clinical Institute Narcotic Assessment) Scalescore and the maintenance DHE dose sublingully. The maintenance dose used in the treatment of individualpatients was regressed on CINA score. The simple regression equeation was: DHE dose(microgram / hour)=1.6309 CINA Score + 6.4554. Further analysis indicated that the inclusion of the exponential termimproved prediction of the DHE dose by 2.2% (thus, a total of 72.06%) of the variance. The regressionequation could be given as: DHE dose(microgram / hour)=CINA~(0. 0276) + 22.0822. The polynomial termimprove prediction of the DHE dose by 3.1% (thus, a total of 73.05% ) of the variance. the regression e-quation could be given as: DHE dose(microgram / hour)=0.0003CINA~3 + 0. 0005CINA~2 + 0.6164CINA +24.9262. In order to determine maintenance DHE dose easily, we recommend the simple regression equa-tion: DHE dose(microgram / hour)=1.6309 CINA Score + 6.4554 for clinical use.

本文报告了二氢埃托啡(DHE)临床治疗38例海洛因成瘾者的药效学研究,发现CINA(Clinical Institute Narcotic Assessment)量表的变化分值(可反映海洛因成瘾者的身体依赖性的程度与二氢埃托啡的48h舌下含服维持剂量有很强的相关性,其相关系数为0.8026;通过回归分析,得出CINA量表的变化分值与二氢埃托啡的48h舌下含服维持剂量的线性回归方程:DHE剂量(μg/h)=1.6309CINA+6.4554。剩余平方和与离差平方和之比为0.2964;通过曲线拟合所得的幂函数曲线方程为:DHE剂量(ug/h)=CINA~(0.0276)+22.0821,剩余平方和与离差平方和之比为0.2794,拟合效果有所改善;通过曲线拟合所得的三次多项式方程为:DHE剂量(μg/h)=0.0003CINA~3-0.0005CINA~2+0.6163CINA+24.9261,剩余平方和与离差平方和之比降低到0.2695,拟合效果进一步提高。由于CINA变化分值可反映海洛因成瘾者的身体依赖程度,根据海洛因成瘾者的身体依赖程度我们可由CINA分值由上述公式得到二氢埃托啡的48h舌下含服维持量。为了便...

本文报告了二氢埃托啡(DHE)临床治疗38例海洛因成瘾者的药效学研究,发现CINA(Clinical Institute Narcotic Assessment)量表的变化分值(可反映海洛因成瘾者的身体依赖性的程度与二氢埃托啡的48h舌下含服维持剂量有很强的相关性,其相关系数为0.8026;通过回归分析,得出CINA量表的变化分值与二氢埃托啡的48h舌下含服维持剂量的线性回归方程:DHE剂量(μg/h)=1.6309CINA+6.4554。剩余平方和与离差平方和之比为0.2964;通过曲线拟合所得的幂函数曲线方程为:DHE剂量(ug/h)=CINA~(0.0276)+22.0821,剩余平方和与离差平方和之比为0.2794,拟合效果有所改善;通过曲线拟合所得的三次多项式方程为:DHE剂量(μg/h)=0.0003CINA~3-0.0005CINA~2+0.6163CINA+24.9261,剩余平方和与离差平方和之比降低到0.2695,拟合效果进一步提高。由于CINA变化分值可反映海洛因成瘾者的身体依赖程度,根据海洛因成瘾者的身体依赖程度我们可由CINA分值由上述公式得到二氢埃托啡的48h舌下含服维持量。为了便于临床计算,建议使用线性回归方程计算二氢埃托啡舌下含服维持剂量。

Objective:To study the effects of tetrahydroprotoberberines(THPBs) on the withdrawal syndromes in morphine-dependent mice and rats. Method: Mice and rats were administered (sc) with morphine hydrochloride in increasing doses.Then the withdrawal syndromes precipitated by diprenorphine (5 mg·kg-1 in mice, 2 mg·kg-1 in rats) were observed 20 minutes after THPBs were given (ip). Result: l-THP, dl-THP and l-SPD,at dose 15, 30, 60 mg·kg-1 (ip), respectively, were able to inhibit mice incidence and freguency of jumping...

Objective:To study the effects of tetrahydroprotoberberines(THPBs) on the withdrawal syndromes in morphine-dependent mice and rats. Method: Mice and rats were administered (sc) with morphine hydrochloride in increasing doses.Then the withdrawal syndromes precipitated by diprenorphine (5 mg·kg-1 in mice, 2 mg·kg-1 in rats) were observed 20 minutes after THPBs were given (ip). Result: l-THP, dl-THP and l-SPD,at dose 15, 30, 60 mg·kg-1 (ip), respectively, were able to inhibit mice incidence and freguency of jumping and body weight loss significantly. Similarly, behavioral withdrawal syndromes of rats, i.e.enraging, teeth chattering, wet dog shakes,jumping etc, were greatly depressed; diarrhea, salivation and weight loss(1h)were also reduced by l-THP and dl-THP(10, 20, 40 mg·kg-1,ip). Abstinence syndrome scores were decreased as doses were increased. Furthermore,l-SPD 10 mg·kg-1 could reduce rat weight loss at 24 hour, although its effects inhibiting withdrawal syndromes were not dose-related. Conclusion:THPBs could inhibit abstinence syndroms in morphine-dependent mice and rats,which suggested that it may be useful in clinical detoxification.

目的··:观察四氢原小檗碱同类物(THPBs)对吗啡依赖小鼠和大鼠戒断症状的影响。方法··:以连续递增剂量方式sc盐酸吗啡,建立吗啡依赖小鼠和大鼠模型,ipTHPBs20min后,用环丙羟丙吗啡(小鼠5mg·kg-1,大鼠2mg·kg-1,ip)催瘾。结果··:小鼠分别ipl-四氢巴马汀(l-THP,15,30,60mg·kg-1)、l-千金藤啶碱(l-SPD,15,30,60mg·kg-1)和dl-四氢巴马汀(dl-THP,15,30,60mg·kg-1)可显著抑制其跳台反应,降低跳台次数,减少体重下降。大鼠分别ipl-THP(10,20,40mg·kg-1)和dl-THP(10,20,40mg·kg-1)能够抑制1h体重下降,大大改善戒断时的行为表现,减轻腹泻和流涎,症状评分随剂量增加而下降。l-SPD抑制大鼠戒断症状作用虽无剂量依赖关系,但10mg·kg-1却可减轻大鼠24h体重下降。结论··:THPBs可缓解吗啡依赖小鼠和大鼠戒断症状,可能具有临床应用价值。

Objective: To investigate drug craving in heroin addicts in drug-free condition after clinical detoxification in China. Method: 705 inpatient heroin addicts after clinical treatment in compulsory drug detoxification units in Beijing and Chongqing were investigated. A single-item self-rating scale was used to assess the intensity of craving. Result: There were 38.7% heroin-addicted patients feeling drug craving during the session of investigation. There was no difference in the fluctuating craving...

Objective: To investigate drug craving in heroin addicts in drug-free condition after clinical detoxification in China. Method: 705 inpatient heroin addicts after clinical treatment in compulsory drug detoxification units in Beijing and Chongqing were investigated. A single-item self-rating scale was used to assess the intensity of craving. Result: There were 38.7% heroin-addicted patients feeling drug craving during the session of investigation. There was no difference in the fluctuating craving levels among the groups of one month, two months, three months, and over three months after clinical detoxification(F=1.345,P=0.259).There was relationship between the intensity of craving and cigarette smoking(standard regression coefficient γ=0.225, t=6.128, P<0.001). Conclusion: Drug craving lasts long time after clinical detoxification.

目的··:观察国内临床脱毒后未染毒的海洛因依赖者的渴求状况。方法··:采用单项目的自评量表 ,对705例在北京和重庆地区的强制戒毒机构脱毒后的住院者进行药物渴求程度调查。结果··:在调查期间 ,有38.7 %的被调查者有不同程度的药物渴求。临床脱毒后 ,一个月、二个月、三个月及三个月以上 ,渴求分值的变化没有显著性(F=1.345,P=0.259)。渴求强度与吸香烟的数量之间有相关关系 (标准化回归系数为0.225,t=6.128,P<0.001)。结论·· :部分海洛因依赖者临床脱毒后 ,药物渴求持续存在

 
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