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vascular events
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  血管事件
     Mean score of MMSE (-2.3±1.7),NPI(12.6±15.3)and ADL(8.9±9.4)per year in the new vascular events group deteriorated significantly in comparison with that in the non-vascular events group(-1.1±1.8,2.4±15.3,2.2±6.9;P<0.01).
     新发血管事件组的MMSE(-2.3±1.7)、NPI(12.6±15.3)和ADL(8.9±9.4)评分较未发生血管事件组恶化迅速(分别为-1.1±1.8、2.4±15.3和2.2±6.9)(P<0.01)。
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     The summary rate ratio for vascular events,compared with placebo,was 0.92 (0.67 to 1.26)for naproxen,1.51(0.96 to 2.37)for ibuprofen,and 1.63(1.12 to 2.37)for diclofenac.
     与安慰剂比较血管事件的总体比率如下:萘普生0.92(0.67~1.26),布洛芬1.51(0.96~2.37),双氯芬酸1.63(1.12~2.37)。
短句来源
     Overall,the incidence of serious vascular events was similar between a selective COX-2 inhibitor and any traditional NSAID (1.0%/year v 0.9%/year;1.16,0.97 to 1.38;P=0.1).
     总的来说,严重血管事件的发生率在选择性 COX-2抑制剂和任何传统 NSAID 之间没有差异(1.0%/年比0.9%/年;1.16,0.97~1.38;P=0.1)。
短句来源
     Among trials of at least one year's duration(mean 2.7 years),the rate ratio for vascular events was 1.45(1.12 to 1.89;P=0.005).
     在为时至少1年的试验中(平均2.7年),血管事件的率比是1.45(1.12~1.89;P=0.005)。
短句来源
     Results In placebo comparisons,allocation to a selective COX-2 inhibitor was associated with a 42% relative increase in the incidence of serious vascular events(1.2%/year v 0.9%/year;rate ratio 1.42,95% confidence interval 1.13 to 1.78; P=0.003),with no significant heterogeneity among the different selective COX-2 inhibitors.
     结果:在与安慰剂对比的试验中,选择性COX-2抑制剂使严重血管事件发生率增加42%(1.2%/年比0.9%/年;率比1.42,95%可信区间1.13~1.78;P=0.005); 不同的选择性 COX-2抑制剂之间没有显著性差异。
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  “vascular events”译为未确定词的双语例句
     In 20 mg group, the incidence of cardiocerebral vascular events such as recurrent angina pectoris(AP),heart failure (HF),arrhythmia was lower than that of 10mg group during hospitalization (P<0.05). During the 12-month's follow-up the incidence of AP,HF, PTCA/CABG,arrhythmia and re-hospitalization in 20 mg group was significantly lower than that in 10mg group (P<0.05).
     在住院期间20mg组复发性心绞痛(AP)、心力衰竭(HF)、心律失常较10mg组明显降低(P<0.05),随访期间20mg组AP、HF、心律失常、PTCACABG、因心肌缺血再住院较10mg组明显降低(P<0.05)。
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     Conclusion There is correlation between the platelet inhibition rate and main heart and brain vascular events in CHD patients during 6 months after stenting.
     结论冠心病患者支架置入术后的血小板抑制率与6个月的主要心脑血管事件相关。
短句来源
     Conclusions VaD-L is characterized by the deterioration of cognitive functions, neuropsychiatric symptoms and activity of daily life,which could be accelerated by the new vascular events.
     结论:VaD-L患者随病程进展,其认知、神经精神症状和日常生活能力均出现恶化.且新发血管性事件能显著加重其神经精神症状及认知、日常生活能力的衰退。
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     Objectives To investigate the relationship between homocysteine (Hcy), folic acid, vitamin B12(VitB12),lipids and the carotid artery atherosclerosis(CAAs) and the significance of their levels in predicting cardiac and cerebral vascular events of older patients.
     目的 比较血清同型半胱氨酸、叶酸、维生素B12 (VitB12 )、血脂等与颈动脉粥样硬化(CAAs)程度的关系 ,探讨其血浓度在预测老年人心脑血管事件发病中的意义。
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     The serum Lp(a) level was positively correlated with protein concentration in the 24 hours peritoneal fluid and with Tch and LDL C level of serum and fibrinogen level of serum( P <0 05). The positive correlation was also found between the serum level of Lp(a) and clinical manifestations (abnormal echocardiography,ECG and cardiac and cerebral vascular events).
     HD与PD患者血Lp(a)水平与超声心动图异常(P <0 0 5)、ECG异常 (P <0 0 0 1)及心脑血管事件的发生 (P <0 0 1)、2 4h腹水蛋白质浓度 (P <0 0 1)、血Tch及LDL C浓度 (P <0 0 5)、纤维蛋白原 (P <0 0 5)呈正相关 ;
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  相似匹配句对
     EVENTS
     新闻事件
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     Events
     事件
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     Does a birthday predispose to vascular events?
     出生日期是否与易发血管事件相关
短句来源
     Cross analysis was conducted between smoking and vascular events.
     吸烟和血管事件之间进行交互分析。
短句来源
     vascular invasion;
     血管受侵犯;
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  vascular events
Aspirin (acetylsalicylic acid) is one of the main therapeutics in prevention of thrombo-embolic vascular events.
      
Because of the possible increased risk of ischemic vascular events, carriers of these genetic polymorphisms may be resistant to the antithrombotic effects of ASA and should be considered for additional or alternative treatment.
      
The literature supports multiple, potentially interactive etiologies for the development of vascular events in these patients, suggesting that their development is not simply a phenomenon related to radiation therapy.
      
In one clinicopathological correlation, coagulative necrosis of the white matter was observed, identical histologically to those changes recognized as delayed vascular events following radiotherapy.
      
The causes of sudden death are many in this clinical setting also, but dominated by ventricular arrhythmias and vascular events.
      
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The leading causes of death in a population of 120 000 in Changsha and vicinity in 1985 and 1986 were studied The total mortality was l,584,with 1,494 of these over 30 years of age.The death rate of the latter group was 11.03%.Cardiovascular diseases,including cor pulmonale and coronary heart disease,were the number one killer,The 2nd leading cause of death was stroke. Cardio-and cerebro-vascular events accounted for 56.21% of the total deaths .The 3rd leading cause of death was tumor (17.93%) .The 4th...

The leading causes of death in a population of 120 000 in Changsha and vicinity in 1985 and 1986 were studied The total mortality was l,584,with 1,494 of these over 30 years of age.The death rate of the latter group was 11.03%.Cardiovascular diseases,including cor pulmonale and coronary heart disease,were the number one killer,The 2nd leading cause of death was stroke. Cardio-and cerebro-vascular events accounted for 56.21% of the total deaths .The 3rd leading cause of death was tumor (17.93%) .The 4th was accidents (8.3%) .94.3% of the patients were more than 30 years old at the time of death. Among 111 sudden deaths,the most important causes were coronary heart disease and stroke.The sudden death rate was 81.9 / 105.Predisposing factors could be found in more than 50%.The proportion of sudden deaths found in the population over 60 years of age increased significantly.Therefore,prevention of cardiovascular disease is very important at this time.

本文报告长沙地区12万人口中1985,1986两年30岁以上死亡者共1494人;其主要死因为心血管疾病,脑中风、肿瘤次之。心血管疾病中,以肺源性心脏病死亡率最高,冠状动脉性心脏病次之。猝死111人,60岁以上者猝死率明显增加。

Objective To investigate changes of platelet glycoproteins in patients with diabetes mellitus(DM) type Ⅱ and their clinical significance. Methods Seventy DM patients and 28 normal individuals entered in this study. The platelet glycoproteins Ⅰb, Ⅱb, Ⅲa and P selectin were analyzed by flow cytometry (FCM). Platelet surface P selectin was measured by Immunoradiometric analysis (IRMA),and plasma P selectin concentration by ELISA. Results On FCM, the P selectin expression on platelets of patients with...

Objective To investigate changes of platelet glycoproteins in patients with diabetes mellitus(DM) type Ⅱ and their clinical significance. Methods Seventy DM patients and 28 normal individuals entered in this study. The platelet glycoproteins Ⅰb, Ⅱb, Ⅲa and P selectin were analyzed by flow cytometry (FCM). Platelet surface P selectin was measured by Immunoradiometric analysis (IRMA),and plasma P selectin concentration by ELISA. Results On FCM, the P selectin expression on platelets of patients with vascular diseases [(10.28±4.86)%] was higher than that of normal subjects [(3.75±1.83)%] (P<0.01) and patients without vascular diseases [(4.25±2.29)%] (P<0.01). Similar results were obtained using IRMA.Plasma P selectin concentration in patients with vascular diseases [(6.18±3.20)μg/L] was higher than that of control group [(3.43±1.56)μg/L](P<0.05) and that of patients without vascular diseases [(3.71±2.12)μg/L] (P<0.05). On the contrary, the platelet surface GPⅠb expression in patients with vascular diseases [(86.35±11.00)%] was remarkably lower than that of normal subjects [(92.63±7.55)%] (P<0.05), while platelet GPⅡb and Ⅲa were not changed in any cases. Conclusion The P selectin levels in plasma and on platelet surface were increased while platelet membrane GPⅠb was decreased in DM type Ⅱ patients with vascular events.

目的观察Ⅱ型糖尿病患者血小板膜糖蛋白的变化及其临床意义。方法应用流式细胞术(FCM)观察70例Ⅱ型糖尿病患者及28名正常人血小板膜上GPⅠb、Ⅱb、Ⅲa及P选择素的表达。以免疫放射法(IRMA)测定血小板膜P选择素分子数,并以酶联免疫法(ELISA)对血浆中的P选择素进行检测。结果FCM测得的血小板膜上P选择素表达阳性率,糖尿病伴血管病患者为(10.28±4.86)%,明显高于正常人的(3.75±1.83)%(P<0.01)及无血管病变者的(4.25±2.29)%(P<001)。用IRMA法测得的结果与FCM类似。血浆中P选择素浓度伴血管病变组(6.18±3.20)μg/L亦高于正常对照组的(3.43±1.56)μg/L(P<0.05)及无血管病变组的(3.71±2.12)μg/L(P<005)。相反,血小板上GPⅠb的表达在糖尿病伴血管病变组为(86.35±11.00)%明显低于正常对照组的(9263±7.55)%(P<0.05)。而血小板GPⅡb、Ⅲa的表达无改变。结论有血管病变的Ⅱ型糖尿患者血小板膜上和血浆中P选择素升高,而GPⅠb降低。

Extensive, large, rendomized, double-blind,multicentre, controlled clinical trials conducted since 1980s have evidenced that the traditional clinical trials based on the experience and deductions e.g. ,only from some clinical laboratory findings were unable to mirror patients' long- term prognosis. In order for us to have a proper evaluation on new drugs and those already on the market, it is time for change shifting from so- called "anecdotal" to "evidence -based medicine" looking at outcomes including total...

Extensive, large, rendomized, double-blind,multicentre, controlled clinical trials conducted since 1980s have evidenced that the traditional clinical trials based on the experience and deductions e.g. ,only from some clinical laboratory findings were unable to mirror patients' long- term prognosis. In order for us to have a proper evaluation on new drugs and those already on the market, it is time for change shifting from so- called "anecdotal" to "evidence -based medicine" looking at outcomes including total mortality, serious cardio- and cerebro- vascular events, quality of life, and pharmaco-economics . And, in turn, the development of "evidence-based medicine" and clinical guidelines will have a positive impact on the new drug R&D, clinical practice, health economics and health - care decision making.

80年代以来的大规模、随机、双盲、多中心、安慰剂对照临床试验证明,以经验和推论,如以一些临床化验指标为依据的传统临床试验不能反映病人的长期预后。为了对新药和已上市药物作出恰当的评价,应当从所谓“众说纷坛”转向注重和评价病人预后,包括总死亡率、重要心脑血管事件、生活质量、卫生经济学等的“循证医学”。反过来,“循证医学”和临床治疗指南的发展将对新药的研究与开发、医生的临床实践、药物经济学、医疗保健服务决策等带来积极和正面的影响。

 
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