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binding group
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  结合基团
     The binding sites of Cu(II), Ni(II) are same as those at physiological pH, they are all located at the N-terminal sequence of HSA or BSA, and coordinated with -NH2, imidazoyl and two pcptide nitrogens. In Cu(II )-HSA, the fifth binding group is COO- of Asp1. Above pH effect has also been discussed.
     Cu(Ⅱ)、Ni(Ⅱ)结合位置与生理pH下的相同,均在白蛋白的N端三肽段上,与Asp~1的α-NH_2、His~3的咪唑基N及两个去质子肽氮配位,Cu(Ⅱ)在HSA中的第五结合基团为Asp~1的羧基。 本文还对上述pH效应进行了讨论。
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  “binding group”译为未确定词的双语例句
     Results:The dissociation constant(KD) of electro-acupuncture and 8-OH-DPAT groups was significantly lower than that of binding group.
     结果电针和8-OH-DPAT组KD值显著低于捆绑对照组;
     Carboxyl group might be the binding group of acceptor substrate for GnT V, but the non substrate binding essential group for GnT III and non essential for GnT IV, respectively.
     胍基可能也参与GnT-II和供体底物结合,而对GnT-IV和GnT-V分别是不参与底物结合的必需基团以及不必需基团。 羧基对GnT-V可能参与和受体底物结合,而对GnT-II和GnT-IV分别是不和底物结合的必需基团和不必需基团。
短句来源
     Results:The dissociation constant(KD) of electro-acupuncture and 8-OH-DPAT groups was significantly lower than that of binding group.
     结果:电针和8-OH-DPAT组KD值显著低于捆绑对照组;
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     Compared with low-level expression of hhlim in cardiac muscle of controls, the contents of hhlim mRNA and protein increased significantly in experimental group. The expression of hhlim in abdominal aorta binding group increased dramatically than that of the swimming group.
     RT- PCR和 Western blot结果显示 ,对照组大鼠心肌细胞 hhlim表达较低 ,运动组和腹主动脉结扎组大鼠 hhlim表达明显增加 ,以腹主动脉结扎组增加最明显。
短句来源
     Methods: After free-running,hamsters were divided into electro-acupuncture group,8-OH-DPAT group,photic stimuli group and binding group rando mLy. Electro-acupuncturing "Baihui"(Du20),"Changqiang"(Du1),system injecting 8-OH-DPAT,photic and binding stimuli were given respectively at circadian time 9(CT9) in the third day after constant darkness.
     方法:金黄地鼠经驯化进入自由运行状态后,于DD第三天CT9给予电针、8-OH-DPAT、光脉冲导引、捆绑导引刺激。
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  相似匹配句对
     The P&T Group
     巴马丹拿集团
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     In group K.
     K.
短句来源
     The Prediction of Binding Free Energies for a Group of Trypsin Inhibitors
     一组胰蛋白酶抑制剂结合自由能的预测
短句来源
     protein binding;
     蛋白结合;
短句来源
     The Average Binding Energies of the Atomiv Valence Orbitals and Group Electronegativities
     原子价层轨道平均结合能与基团电负性
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  binding group
Based on this review, an idea is presented to use synthetic flavivirus peptides with an amino acid motif to fit with the HLA class I peptide binding group of HLA haplotypes prevalent in a given population in an endemic area.
      
It appears likely that a hydrophilic substituent in a certain region of the analgesic pharmacophore may also interact with the receptor as a secondary binding group.
      
Because of the crucial role of zinc in the activity of the enzyme, the design of inhibitors is usually based upon a so-called zinc binding group (ZBG).
      
A well defined polymorphism of vitamin D-binding/ group-specific component (GC) resides in exon 11.
      
These molecules are self-assembled on a GaAs surface to which they are attached through a carboxylate binding group.
      
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The particularity of crosslinking of ethylene - propylene (EPDM)elastomer has been studied using torque - time curve (at 150℃),equilibrium modulus and swelling, physico - property tests and infraredspectra (MIRIR). The torque of EPDM increases linearly with continually heatingat 150℃ after obtained equilibrium density of chemical crosslinkingwith sulfur, accelereators or DCP. Therefore, the optimum crosslinkingtime can not be obtained with torque - time curve (Viscosmeter), butit can be obtained with equilibrium...

The particularity of crosslinking of ethylene - propylene (EPDM)elastomer has been studied using torque - time curve (at 150℃),equilibrium modulus and swelling, physico - property tests and infraredspectra (MIRIR). The torque of EPDM increases linearly with continually heatingat 150℃ after obtained equilibrium density of chemical crosslinkingwith sulfur, accelereators or DCP. Therefore, the optimum crosslinkingtime can not be obtained with torque - time curve (Viscosmeter), butit can be obtained with equilibrium modulus or equilibrium swelling. This particularity of crosslinking of EPDM is produced by thecontinually chemical reactions of residual free sulfur, accelerators orDCP in EPDM, after formation of chemical crosslinking, and thesereactions produced the bound groups (such as - C=S or [R-O]~-)of polymer chain. The impact resilience of EPDM is independente of crosslinking,while it is characteristic of macromolecular entangement and itsreaction with fillers.

本文提出采用硫黄、促进剂体系和过氧化物体系作交联剂,测定在150℃温度下,各自交联过程中生成物的横键密度(由拉伸平衡模量、最大溶胀测出)和物性,以及红外分光光度计测定其表层(20微米)内的化学基团变化。结果分析证明:国产乙丙弹性体在化学交联过程中,采用测定扭矩变化动力曲线的方法(称硫化仪),不能确定达到平衡模量或平衡溶胀的最佳交联时间。国产乙丙弹性体的交联动力曲线(扭矩—时间)特点,是由于化学交联剂生成横键后,继续参与化学反应,形成聚合物大分子键侧基团等产物的结果:乙丙弹性体的打击回弹性与其交联横键无关,是EPDM聚合物本身及其与填充料形成的缠结点作用的表征。

A review desci bes the preparation of polymers with binding groups in the cavities of original template molecules throngh an imprinting procedure of the template for separation of organic compounds and optical resolution of racemates Selectivity in separation is also discussed.

本文评述了采用模板聚合方法制得的带结合功能基和孔穴的聚合物在有机化合物分离和外消旋体拆分中的应用并讨论了它们的分离选择性。

By using l-ethyl-3-(3-dimethylaminopropyl)-carbodiimide(EDC) ,2,4,6-trinitrobenzylsulfonic acid and diacetyl for the chemical modification of carboxyl,amino and guanido group of human glutathione S-transferase (GST-π) respectively to study the kinetics for inactivation of enzyme revealed that the corresponding moles of inhibitor needed for fully inactivation of the enzyme were 1.0, 1.08, 0.98/enzyme subunit, suggusting that only one mole of carboxyl, amino and quanido group for each participated...

By using l-ethyl-3-(3-dimethylaminopropyl)-carbodiimide(EDC) ,2,4,6-trinitrobenzylsulfonic acid and diacetyl for the chemical modification of carboxyl,amino and guanido group of human glutathione S-transferase (GST-π) respectively to study the kinetics for inactivation of enzyme revealed that the corresponding moles of inhibitor needed for fully inactivation of the enzyme were 1.0, 1.08, 0.98/enzyme subunit, suggusting that only one mole of carboxyl, amino and quanido group for each participated in the active center of GST-π subunit. The substrate and its analogs, glutatione, S-hexylglutathione and S-octylglutathione, protected GST-π from modification by the above inhibitors and the rate constant of pseudo-first order reaction k1 was remarkably decreased in the presence of these protectors, indicting that carboxyl, amino and guanido groups were involved in the GSH binding site of GST-π. The authors had proved that one fast-reacting sulfhydryl group also participated in the binding of GST-π with GSH , so that at least 4 different groups were the binding groups of each subunit. The specific modification of amino group by TNBS was also verified and the ionic linkages between GST-π and GSH were proposed.

用1-乙基-3-(3-二甲基氨基丙基)-碳二亚胺(EDC),2.4.6.三硝基苯磺酸(TNBS)和丁二酮(DIC)分别修饰人胎盘型谷胱甘肽S-转移酶(GST-π)的羧基、氨基和胍基,研究了酶的失活动力学,发现引起一分子酶亚基全部失活所需抑制剂的分子数分别为1.0、1.08和0.98,提示每亚基只有一个羧基、氨基和胍基参与酶的活性中心。底物及其类似物谷胱甘肽,S-己烷或S-辛烷谷胱甘肽可保护GST-π免受上述抑制剂的修饰,使假一级反应速度常数k_1明显降低,说明羧基、氨基和胍基是GST-π和GSH结合部位的组成基团。作者曾证明GST-π中的一个快反应巯基也参与酶与GSH的结合,故至少有四个不同的基团是酶亚基的结合基团,本文还对TNBS对氨基修饰的特异性作了验证,并讨论了GST-π与GSH结合时形成离子键的情况。

 
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