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soluble tumor
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  可溶性肿瘤
     Objective: To appraise the changes of plasma levels of soluble tumor necrosis factor-αreceptor (sTNFαR) and its clinical significance in severe viral hepatitis B. Method: Plasma levels of sTNFαR were detected with radioimmuno-precipitation-polyethylene glycol assay in 21 patients of severe viral hepatitis B, and 10 normal subjects and 20 patients with chronic active hepatitis B were used as controls.
     目的:为了探讨重型乙型肝炎患者血浆可溶性肿瘤坏死用于受体(sTNFαR)变化及其临床意义。 方法:本研究采用放射免疫沉淀一聚乙二醇分析法测定了21例重型乙型肝炎患者血浆sTNFαR水平,并以10例正常人和20例乙型慢性活动性肝炎作对照。
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  “soluble tumor”译为未确定词的双语例句
     DATA SOURCES: A computer-based online search of Pubmed and highwire was undertaken to identify the literature on the gene therapy for rheumatoid arthritis published in English from January 1997 to June 2006 with the key words of "gene therapy, rheumatoid arthritis, interleukin-1 receptor antagonist, soluble tumor necrosis factoreceptor".
     资料来源:应用计算机检索Pubmed及highwire1997-01/2006-06有关类风湿关节炎基因治疗的文献,检索词“gene therapy,rheumatoid arthritis,interleukin-1 receptor antagonist,soluble tumor necrosis factoreceptor”,并限定文章语言种类为English。
短句来源
     The level(12.14±3.18)of IRIAC in soluble tumor vaccine treatment group markedly decreased than that(17.25±3.8)in controls(P<0.01).
     溶瘤苗治疗组IRIAC水平(12.14±3.18)明显低于未治疗对照组水平(17.25±3.8,P<0.01)。
短句来源
     Objective To investigate the expression of T cell early activation marker(CD 69 )on CD + 4 and CD + 8 lymphocytes in peripheral blood and the levels of soluble tumor necrosis factor receptor 1 (sTNF-R1) and sTNF-R2 in serum and bone marrow in patients with myelodysplastic syndrome(MDS).
     目的 研究骨髓增生异常综合征 (MDS)外周血CD+ 4 、CD+ 8T细胞早期激活标志CD69的表达及血清、骨髓可溶性肿瘤坏死因子受体 1、2 (sTNF R1、2 )的水平及其意义。
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     The Effect of Soluble Tumor Antigen on the Immune Function of CD 3AK Cells in Mice
     可溶性肿瘤抗原对小鼠CD_3AK细胞生物免疫功能的影响
短句来源
     Significance of Changes of Serum Soluble Tumor Necrosis Factor Receptor-1(sTNF-1R) and IL-15 in Patients with Acute Pancreatitis
     急性胰腺炎患者血清sTNF-1R和IL-15的变化意义
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  相似匹配句对
     EXPERIMENTAL STUDY OF TUMOR'S SOLUBLE ANTIGEN
     肿瘤可溶性抗原实验研究
短句来源
     Expression of soluble Fas in ascites of patient with gastrointestinal tumor
     胃肠道肿瘤患者腹水中可溶性Fas的表达及其临床意义
短句来源
     The soluble hydrogenase from C.
     光合细菌 C.
短句来源
     MicroRNA and Tumor
     微RNA与肿瘤
短句来源
     Connexin and tumor
     细胞间隙连接蛋白与肿瘤
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  soluble tumor
Delivery of Soluble Tumor Necrosis Factor Receptor from In-Situ Forming PLGA Implants: In-Vivo
      
The Soluble Tumor Necrosis Factor Receptor I Is an Early Predictor of Local Infective Complications After Colorectal Surgery
      
The release of soluble tumor necrosis factor receptors was strongly (80-90%) inhibited in the presence of the neutralizing antibody.
      
Injection of tumor necrosis factor-α in humans elicited a significant, instantaneous (after 15 min) increase in the plasma concentrations of both types of soluble tumor necrosis factor receptors.
      
The role of tumor necrosis factor-α in the shedding of soluble tumor necrosis factor receptors in endotoxemia was investigated.
      
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The study presented that soluble tumor antigens (STA ) and anti-CD3' McAb costimulated peripheral blood mononuclear cells twgen rate tumor killer cells which were predominantly CD8+ T cells,called T-AK cells. Prolifera-tion of T-AK cells was rapid in vitro and low IL-2-dependcnt in comparison with that of LAK cells and CD3 AK cells. T-AK cells expanded 24-flod in 14 days' culture,8-fold higher than CD3-AK cells and 15-fold higher than LAK cells, and even successively grew till 21st day. T-AK cell...

The study presented that soluble tumor antigens (STA ) and anti-CD3' McAb costimulated peripheral blood mononuclear cells twgen rate tumor killer cells which were predominantly CD8+ T cells,called T-AK cells. Prolifera-tion of T-AK cells was rapid in vitro and low IL-2-dependcnt in comparison with that of LAK cells and CD3 AK cells. T-AK cells expanded 24-flod in 14 days' culture,8-fold higher than CD3-AK cells and 15-fold higher than LAK cells, and even successively grew till 21st day. T-AK cell population contained CD3+86% ,CD4+20% ,CD8 + 95%,CD16+ 40% ,CD25+53% ,and they were heterogenic cell population consisting of mainly CD8+ T cells. T-AK cells killed the related target cells whose STA costimulated them with high affinity,and also killed NK-sensitive and NK-resistant target cells. These results suggest that non-MHC-restricted CD8' cytotoxic T cells could be induced by STA and anti-CD3' McAb costimulation.

用可溶性肿瘤抗原和CD3单克隆抗体共同刺激外周血单个核细胞(PBMC)产生CD8~+T细胞为主的杀瘤细胞,称其为T-AK细胞。与LAK细胞和CD3-AK细胞比较,T-AK细胞扩增快、低依赖IL-2,培养14天细胞数扩增24倍,比CD3-AK细胞高8倍,比LAK细胞高15倍,并能持续生长21天。T-AK细胞中含CD3~+86%、CD4~+20%、CD8~+95%、CD16~+40%、CD25~+53%,它们是CD8~+T细胞为主的异质性细胞群。T-AK细胞对刺激它的STA来源的靶细胞高亲和性杀伤,杀伤率>90%,对NK敏感和不敏感细胞也有杀伤,表现非MHC限制杀伤。

We evaluated soluble interleukin 2 and soluble tumor necrosis factor I receptors serum levels in 80 chronic peritoneal dialysis (PD) and 62 hemodialysis patients (HD).The results showed:①Lymphocytic activation is more stable in PD patients than in HD.②Higher sIL 2R in PD patients can′t only be interpreted by declined clearance of sIL 2R,but also by immune regulation.③Immune function lowered in older patients is related to the ...

We evaluated soluble interleukin 2 and soluble tumor necrosis factor I receptors serum levels in 80 chronic peritoneal dialysis (PD) and 62 hemodialysis patients (HD).The results showed:①Lymphocytic activation is more stable in PD patients than in HD.②Higher sIL 2R in PD patients can′t only be interpreted by declined clearance of sIL 2R,but also by immune regulation.③Immune function lowered in older patients is related to the decreased ALB.The results suggested that increasing of mean sIL 2R、STNFR1 serum levels could resulted in reduced clinical inflammatory response,and might be related to infection in maintained dialysis patients.

测定了80例慢性腹透患者(PD)及62例血透患者(HD)的sIL-2R、STNFR1,结果表明:①PD者淋巴细胞活化较HD者稳定;②透析患者sIL-2R增高不能单用清除减少来解释,可能还存在免疫调节;③高龄者免疫功能(sIL-2R)降低与ALB降低有关。认为sIL-2R、STNFR1增高可降低宿主炎症反应,可能与长期透析患者极易感染有关

PURPOSE To asses the clinical significance of serum levels of soluble tumor necrosis factor receptorI (sTNFR-I) in gastric cancer patients before and after therapy.METHODS The levels of sTNFR-I in 34 patients with gastric cancer were measured by ELISA before and after surgery or chemotherapy.RESULTS The results were as follows:serum sTNFR-I levels in the gastric cancer patients were significantly higher than those in healthy controls (P<0.01). Correlated to clinical staging, they increased greatly in advanced...

PURPOSE To asses the clinical significance of serum levels of soluble tumor necrosis factor receptorI (sTNFR-I) in gastric cancer patients before and after therapy.METHODS The levels of sTNFR-I in 34 patients with gastric cancer were measured by ELISA before and after surgery or chemotherapy.RESULTS The results were as follows:serum sTNFR-I levels in the gastric cancer patients were significantly higher than those in healthy controls (P<0.01). Correlated to clinical staging, they increased greatly in advanced disease. The frequency of increase in sTNFR-I(82.4%) greatly exceeded that carcinoembryonic antigen (20.6%). sTNFR-I levels in patients were decreased after effective therapy. A value above 3.00ng/ml had a poor prognosis. Among them, 24 patients were tested again during period of 4 to 8 months after therapy,sTNFR-I levels declined to normal in 8 and elevated in the other 16,where the cancerous growth was not controlled or recurred locally or there occurred metastasis.CONCLUSIONS This study suggests that measurment of serum sTNFR-I patients with gastric cancer is of diagnostic and prognostic importance as well as in evaluating the efficacy of treatment.

目的探讨胃癌患者治疗前后血清可溶性坏死因于受体(sTNF-Ⅰ)水平的临床意义。方法应用酶联免疫吸附测定(ELISA)的方法测定了34例胃癌患者sTNFR-Ⅰ水平。结果胃癌患者血清sTNFR-Ⅰ水平明显高于正常人(P<0.01),且与临床分期有关,病情越晚,sTNFR-Ⅰ水平越高,sTNFR-Ⅰ水平超过3.00ng/ml者预后不良;治疗有效者sTNFR-Ⅰ均显著下降(P<0.01),24例治疗后4~8个月再次采血检验,8例无瘤生存者sTNFR-Ⅰ水平降至正常,其余16例肿瘤未控制或复发转移者血清sTNFR-Ⅰ水平升高。结论血清sTNFR-Ⅰ测定对胃癌疗效观察、病情监测及预后判断有重要意义。

 
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