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spontaneous expression
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  自发表达
     Results There was a spontaneous expression of IL-1αmRNA in SCC12F cells in culture system of normal KC,which was increased along with the culture time,and reached the highest expression level in120hours.
     结果SCC12F细胞可在正常KC培养体系中自发表达IL-1αmRNA,其表达水平随细胞培养时间的延长而增强,在120h达到高峰值;
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  自然表达
     Patients with alcoholic cirrhosis showed higher spontaneous expression in TNFα and sTNFRp55, p75 on monocyte than controls.
     结果示AC组TNFα和sTNFRp55、p75自然表达较正常组增强。
短句来源
     After ethanol stimulating, TNFα and sTNFRp55 production did not differentiate between patients and controls, but level of sTNFRp75 was increased, which were also showed in spontaneous expression.
     尽管sTNFRp75表达增高,但这种增高的表达在自然表达中就已经显示出来。
短句来源
  “spontaneous expression”译为未确定词的双语例句
     SPONTANEOUS EXPRESSION OF THE HUMAN COMPLEMENT1 INHIBITOR GENE IN COS-7 CELLS
     人补体C_1-抑制物基因在COS-7细胞中的表达
短句来源
     When the MAPKERK1/2 pathway was blocked by a specific antagonist PD98059, spontaneous expression of IL - 6 and anti - dsDNA antibody in LN PBMC were significantly inhibited.
     应用特异性阻断剂PD98059阻断LN患者PBMC MAPKERK1/2信号通路活化可显著抑制IL-6和抗DS-DNA抗体的自发高表达。
短句来源
     SPONTANEOUS EXPRESSION OF INTELEUKIN-10 mRNA BY PERIPHERAL BLOOD MONONUCLEAR CELLS FROM PATIENTS WITH SLE
     IL-10mRNA在SLE患者外周血单个核细胞上的表达
短句来源
     Results In vitro experiments employing normal PBMC showed that MP downregulated both MBP induced IFN γ and spontaneous expression of IFN γ, and no effect on IL 10 secreting cells was found.
     结果 显示MS患者IFN γ分泌细胞水平高于对照组 ,甲基强的松龙使MS患者IFN γ分泌细胞减少 ,对IL 10分泌细胞无明显影响。
短句来源
     Results In vitro experiments employing normal PBMC showed that Dexamethsone downregulated both MBP induced IFN γ and spontaneous expression of IFN γ,no effect on IL 10 secreting cells was found.
     结果 显示 MS患者 IFN- γ分泌细胞水平高于对照组 ,Dex使 MS患者 IFN- γ分泌细胞减少 ,对 IL- 10分泌细胞无明显影响。
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  相似匹配句对
     The expression
     在交界瘤、良性瘤中无表达。
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     The expression of E.
     研究了E.
短句来源
     Expression of FasL on Trophoblasts of Recurrent Spontaneous Abortion
     复发性自然流产患者绒毛滋养细胞FasL的表达
短句来源
     Expression of RXRa on Placentas in Patients with Spontaneous Abortion
     复发性自然流产患者绒毛RXRα的表达
短句来源
     SPONTANEOUS PNEUMOTHRAX
     自发性气胸(附22例临床及X线分析)
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  spontaneous expression
The LI children performed significantly more poorly than did controls in both comprehension and spontaneous expression of vocal affect.
      
A Psychometric Evaluation of the Facial Action Coding System for Assessing Spontaneous Expression
      
Nonviolent families were characterized by spontaneous expression of feelings and problems, shared pleasurable activities and goals, and an emphasis on personal rights and freedoms.
      
There was a spontaneous expression of procoagulant activity in two patients with active untreated Whipple's disease.
      
Children's play: The dynamic and spontaneous expression of the interface of emotion and cognition
      
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The activity of interleukin-2 (IL-2) and expression of interleukin-2 receptor (IL-2 R) were measured in children with acute glomerulonephritis (AGN) in order to detemine the mechanism of the disease Our results showed that the activity of IL-2 in peripheral blood lymphocytes (PBL) of children with AGN was lower than that tof the control group (P<0.05), and the unmber of expression of IL-2 in PHA-stimulated PBL was also lower than that of the control grroup (P<0.005), while the number of spontaneous expression...

The activity of interleukin-2 (IL-2) and expression of interleukin-2 receptor (IL-2 R) were measured in children with acute glomerulonephritis (AGN) in order to detemine the mechanism of the disease Our results showed that the activity of IL-2 in peripheral blood lymphocytes (PBL) of children with AGN was lower than that tof the control group (P<0.05), and the unmber of expression of IL-2 in PHA-stimulated PBL was also lower than that of the control grroup (P<0.005), while the number of spontaneous expression of IL-2R in UnstimulatedPBL was higher than that of the control group (P<0.01). The data suggested that the Occurrence of the disease might result from the decreased ability of cellular immune resparse due to the function impairment of the T lymphocytes and the disorder of the immunoregulation in children with AGN due to the function disorder of T-B lymphocytes.

为进一步明确急性肾小球肾炎(AGN)的发病机理,我们检测了AGN患儿外周血淋巴细胞白细胞介素-2(IL-2)活性及白细胞介素2受体(IL-2R)表达能力。结果表明AGN患儿外周血淋巴细胞IL-2活性低于对照组(P<0.05);经PHA刺激激活后的淋巴细胞IL-2R表达能力低于对照组(P<0.005);而未经PHA刺激的淋巴细胞IL-2R表达能力高于对照组(P<0.01)。提示该病的发生是由于患儿T淋巴细胞功能不足,免疫应答能力下降:T—B淋巴细胞功能失调,机体免疫调节功能紊乱的结果。

We evaluated the spontaneous production of tumor necrosis factor α(TNFα) and soluble tumor necrosis factor receptor (sTNFR) and determined whether TNFα and sTNFR expression on mononuclear cells in vitro in patients with alcoholic liver cirrhosis (AC) was induced by lipopolysaccharide (LPS) or ethanol stimulation. Their levels were examined by an enzyme linked immunosorbent assay (ELISA). Patients with alcoholic cirrhosis showed higher spontaneous expression in TNFα and sTNFRp55, p75 on monocyte than...

We evaluated the spontaneous production of tumor necrosis factor α(TNFα) and soluble tumor necrosis factor receptor (sTNFR) and determined whether TNFα and sTNFR expression on mononuclear cells in vitro in patients with alcoholic liver cirrhosis (AC) was induced by lipopolysaccharide (LPS) or ethanol stimulation. Their levels were examined by an enzyme linked immunosorbent assay (ELISA). Patients with alcoholic cirrhosis showed higher spontaneous expression in TNFα and sTNFRp55, p75 on monocyte than controls. The concentration of TNFα and both sTNFR from LPS stimulated peripheral blood monocyte either in patients or in healthy controls was markedly increased as compared with spontaneous production. The patients showed siginficantly higher level of TNFα and both sTNFRp55, p75 than controls ( P <0.05, P <0.01, P <0.005 respectively). Increased TNFα and both sTNFR expressions following ethanol stimulation were not found neither in patients nor in controls. These data suggest that elevated TNFα and sTNFR levels in serum are correlated with activation of mononuclear cells in vivo, which is closely correlated with endotoxin, but no direct correlation with ethanol is found.

为调查酒精性肝硬化(AC)患者周围血单核细胞肿瘤坏死因子(TNFα)和可溶性肿瘤坏死因子受体(sTNFR)自然表达和是否通过内毒素脂多糖(LPS)或酒精刺激后表达增强,用酶联免疫吸附试验(ELISA)对其进行了定量测定。结果示AC组TNFα和sTNFRp55、p75自然表达较正常组增强。经LPS刺激后TNFα、sTNFRp55、p75的表达不论在AC组还是健康组均较自发性表达增加,但AC组较正常组明显增高,P值分别<0.05,<0.01,<0.05。经酒精刺激后不论AC组还是正常组TNFα、sTNFRp55的表达与自发性表达无差异,虽然sTNFRp75的表达较正常组增高,但这种差异在自发性表达中已显示出来。这些结果提示AC组血清中TNFα和sTNFR水平升高与体内单核细胞活化有关,它的活化受其内毒素影响,酒精对其活化未显示直接作用。持续性TNFα和sTNFR水平增高是促进AC发生和发展的重要因素。

To investigate the activity of mononuclear cells and expressin of TNFα and sTNFR in vitro and vivo in patients with alcoholic cirrhosis (AC), the levels of TNFα and sTNFRp55, p75 in serum of 32 patients with AC and the capacity to produce TNFα and sTNFR were determined in vitro in spontaneous and LPS, ethanol-stimulated mononuclear cells from 12/32 patients by an enzyme linked immunosorbent assay (ELISA). Result and conqlusion: Their levels of TNFα and both sTNFRp55, p75 in serum were markedly increased in patients...

To investigate the activity of mononuclear cells and expressin of TNFα and sTNFR in vitro and vivo in patients with alcoholic cirrhosis (AC), the levels of TNFα and sTNFRp55, p75 in serum of 32 patients with AC and the capacity to produce TNFα and sTNFR were determined in vitro in spontaneous and LPS, ethanol-stimulated mononuclear cells from 12/32 patients by an enzyme linked immunosorbent assay (ELISA). Result and conqlusion: Their levels of TNFα and both sTNFRp55, p75 in serum were markedly increased in patients than in healthy controls. As compared with healthy, the expression of TNFα and sTNFRp55, p75 from LPS stimulated mononuclear cells was also increased in patients with AC. After ethanol stimulating, TNFα and sTNFRp55 production did not differentiate between patients and controls, but level of sTNFRp75 was increased, which were also showed in spontaneous expression. These data suggest that the activation of mononuclear cells and exprssion of TNFα and sTNFR are related to endotoxin in patients with AC. The measurement of TNFα and sTNFR in serum and cells is very important for pathogenesis, assessment of progrossion and prognosis of AC.

为调查酒精性肝硬化(AC)体内外单核细胞肿瘤坏死因子(TNFa)和可溶性肿瘤坏死因子受体(sTNFR)的表达,我们采用酶联免疫方法对32例AC血清及12/32例周围血单核细胞自发性和经乙醇、内毒素酯多糖(LPS)刺激后TNFα和sTNFR的表达进行了检测。结果与结论:血清中TNFα、sTNFRp55、sTNFRp75水平较正常对照组明显升高。与健康者比较,经LPS刺激后的单核细胞在AC组不论TNFα还是sTNFRp55、sTNFRp75都是升高的,而经乙醇刺激后TNFα和sTNRp55在两组之间没有差异。尽管sTNFRp75表达增高,但这种增高的表达在自然表达中就已经显示出来。这些结果提示AC单核细胞活化与TNFα和sTNFR的表达与内毒素有关。TNFα和sTNFR的检测对AC发生机理,病情发展和预后判断有重要意义。

 
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