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up expression
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  表达增高
     Conclusions Down expression of ER and up expression of PCNA in prolactinomas are correlated with invasiveness of prolactinomas, which may serve as the molecule marker of invasiveness in prolactinomas.
     结论ER表达降低及PCNA表达增高与肿瘤的侵袭性有密切关系,可以作为临床判断肿瘤侵袭性的分子标志。
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  “up expression”译为未确定词的双语例句
     To sum up, expression of CD45RO was low while expression of CD20 was high in the group of metastasis of lymphadenoma;
     即有淋巴结癌转移组CD45RO表达低 ,CD2 0表达高 ;
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     Following up expression p53 and Bcl-2, protein expression, P-gp, GST-π affect were obviously changed.
     结论:P-gp、p53、Bcl-2、GST-π等表述与膀胱移行细胞癌的分期有关;
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     LacZ(2×109pfu/ml)through gastra-intestinal artery, liver,spleen,lung and kidney were sampled at 12h,18h,72h,7d,14d,21d and 28d respectively,with X-gal staining was used to check up expression of lacZ gene.
     lacZ(2×109pfu/ml) ,采用X -Gal染色方法检测lacZ基因在各个脏器的表达 ;
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     Conclusion Delayed neuron death was occurred after reperfusion of transiently incomplete forebrain ischemia in rat hippocampus,and at the same time, Aβ was up expression, which is suggested to be an important role of Aβ in neuron death after reperfusion of ischemic lesion.
     结论 大鼠短暂性不全性脑缺血再灌注损伤后 ,海马CA1区神经细胞发生迟发性死亡 ,同时Aβ表达上调 ,提示Aβ可能在再灌注损伤后海马CA1区神经细胞迟发性死亡过程中起重要作用。
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     Moreover, present study reported, for the first time, that Aβ 25-35 (icv) induced up expression of nitric oxide synthase (NOS) in several areas of forebrain and 764 3 blocked this response.
     本文又首次报告Aβ 2 5 35引起前脑多个脑区的一氧化氮合酶(NOS)表达上调 ,76 4 3拮抗此反应。
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     The expression of p53 step up.
     p53阳性表达在新辅助化疗后升高。
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     Expression of E.
     将阳性重组质粒转化表达受体菌E.
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     The expression of E.
     研究了E.
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     Furthermore, AIF expression was up-regulated.
     凋亡诱导因子AIF蛋白的表达也有所增加。
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     UP and COMERS
     隐藏与危险
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  up expression
The catch-up expression of clone 42 may be one example of this altered gene expression.
      
The UP expression constitutes a unique molecular marker that distinguishes this cell type from any other mammalian adipose cell.
      
This apoptosis may be mediated by down-expression of apoptosis-regulated gene Bcl-2 and up-expression of apoptosis-regulated gene Bax.
      
Such parental imprints set up expression differences between the parental alleles in the somatic tissues during subsequent development.
      
In addition to identifying candidate pathways, a few uncharacterized ESTs were also identified and some verified with follow-up expression studies.
      


Getting information and data from test and actual examination,establishing mathematical model from summed up expressions to demonstrating pollution situation of Chihu Lake by computer.

由试验和实际测定取得信息和数据,经数学演绎而得出一些数学表达式,从而建立水质数学模型,在计算机屏幕上描述武山铜矿废水经3个排口进入赤湖对赤湖水体的影响。

Objective To investigate the gene transfer efficiency and lasted time in rat organs by hepatic artery injection with LacZ reporter gene recombinant adenoviruses. Methods Seven groups of rats were injected with Ad.LacZ (2×10 9 pfu/ml) and two groups of rats were injected with PBS 1 ml as control separately through gastra intestinal artery, and liver, spleen, lung, and kidney were gotten at 12 hrs, 18 hrs, 72 hrs, 7 day, 14 day, 21 day, and 28day, respectively. X gal staining was used to check up expression...

Objective To investigate the gene transfer efficiency and lasted time in rat organs by hepatic artery injection with LacZ reporter gene recombinant adenoviruses. Methods Seven groups of rats were injected with Ad.LacZ (2×10 9 pfu/ml) and two groups of rats were injected with PBS 1 ml as control separately through gastra intestinal artery, and liver, spleen, lung, and kidney were gotten at 12 hrs, 18 hrs, 72 hrs, 7 day, 14 day, 21 day, and 28day, respectively. X gal staining was used to check up expression of LacZ gene. Results Expression of LacZ gene was detected in liver 12 hrs after injection, but none were done in spleen, lung, and kidney. Up to 21days, LacZ gene expressed in liver, but the gene expression lasted for only 14 days in spleen, lung, and kidney LacZ gene was not detected in the two control groups in all organs at 7 day. Conclusion When recombinant adenovirus was administrated through hepatic artery, the introduced gene expressed preferentially in liver. This result was the basis of intraarterial administration of cytokines gene to treat liver tumor.

目的 将动脉插管方法应用于重组腺病毒 (Ad .LacZ)介导的标记基因体内导入 ,观察标记基因在大鼠内脏中的转染效率和维持时间。方法  9组大鼠 ,7组于胃十二指肠动脉分别注入Ad .LacZ[2× 10 9pfu/ml(空斑形成单位 /ml) ]各 1ml,2组注入单纯培养液各 1ml,7组实验组分别于 12h、18h、72h、7d、14d、2 1d、2 8d取动物的肝、脾、肺和肾脏 ,2组对照组于 7d取上述脏器 ,采用 β 半乳糖苷酶 (X Gal)染色方法检测LacZ基因在各个脏器的表达。结果 实验组于 12h取材 ,经染色LacZ基因在肝脏中即有表达 ,而此时脾、肺、肾等内脏器官尚未见表达 ;此后 ,18h、72h、7d、14d直至 2 1d该基因在肝脏仍有表达 ,而在其他脏器如脾、肺及肾表达仅维持 14d。对照组动物各个脏器皆无染色。结论 经动脉途径注入重组腺病毒 ,其体内的表达具有器官靶向性。如经此途径注入治疗性的目的基因重组腺病毒 ,其于肝脏表达产物出现时间早 ,并且持续时间较长。本实验结果为将来应用插管方法进行肝病基因治疗奠定了理论基础

Objective To probe into the correlation between expression of urothelial differentiation dependent uroplakins (UP) and differentiation state of bladder cancer. Methods Immunohistochemical stain was applied to 96 cases of different WHO grading bladder cancer, polyclonal UPⅡ-Ⅲ antibody as the primary antibody. Results 100.0%(19/19) of grade Ⅰ transitional cell carcinoma(TCC), and 90.5% (38/42) grade Ⅱ TCC were positive for UP( P =0.40).Whereas,these were statistically higher than that of grade...

Objective To probe into the correlation between expression of urothelial differentiation dependent uroplakins (UP) and differentiation state of bladder cancer. Methods Immunohistochemical stain was applied to 96 cases of different WHO grading bladder cancer, polyclonal UPⅡ-Ⅲ antibody as the primary antibody. Results 100.0%(19/19) of grade Ⅰ transitional cell carcinoma(TCC), and 90.5% (38/42) grade Ⅱ TCC were positive for UP( P =0.40).Whereas,these were statistically higher than that of grade Ⅲ TCC, which was 51.4%(18/35) positive for UP( P =0.0001, the correlation coefficient being 44.5%. The expression of UP was mainly observed at the peripheral and luminal of the papilla in grade Ⅰ and grade Ⅱ TCC of urinary bladder with no statistical significance in these two groups( P1=0.20, P2 =0.21).Whereas,UP expression was at the cytoplasm in grade Ⅲ.Which expression was higher than that of grade Ⅰ and grade Ⅱ ( P =0.0026). Conclusions There is correlation between UP expression and the differentiation of bladder cancer, the better differentiation the higher expression.

目的 探讨尿路上皮分化特异的糖蛋白 (UP)表达与膀胱癌分化程度的相关性。 方法 用免疫组织化学方法研究UPⅡ Ⅲ在 96例膀胱移行细胞癌的表达情况 ,并与膀胱癌的WHO分级进行对照研究。 结果 UP在G1组乳头状移行细胞癌的表达率为 1 0 0 .0 % (1 9/ 1 9) ,G2 组为90 .5 % (38/ 42 ) ,两组间差异无显著性 (P =0 .40 )。但明显高于G3 组的 5 1 .4% (1 8/ 35 ) ,P =0 .0 0 0 1 ,关联系数为 44 .5 %。G1、G2 组UP表达主要在乳头的外周和囊腔 ,两组间差异无显著性 (P1 =0 .2 0 ,P2 =0 .2 1 )。G3 组则主要在胞浆内 ,明显高于G1、G2 组 (P =0 .0 0 2 6 )。 结论 UP表达与膀胱癌分化程度有相关关系 ,膀胱癌分化越好 ,UP的表达比例越高。

 
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