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proteinuria concentration
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  尿蛋白浓度
     Results Compared with NS group, the proteinuria concentration and serum ANA titers in the emodin group were all decreased (P<0.05 and P<0.01). The emodin dosage (0 to 6.25 mg/kg) showed negative correlations with serum ANA titers (P< 0.01) and even a negative linear correlation with the proteinuria concentration (P<0.01).
     结果 与生理盐水组相比,胃饲大黄素的各组小鼠的24h尿蛋白浓度和血清ANA滴度均有所下降(P<0.05和P<0.01),尿蛋白浓度与大黄素剂量(0~6.25mg/kg)呈直线负相关(P<0.01);
短句来源
     Methods Thirty-five BXSB female mice were divided into 5 groups and were respectively fed with different concentrations of emodin and 0. 9% normal saline (NS). Thirty days later,the proteinuria concentration and serum anti-nuclear antibody (ANA) titers were detected.
     方法 已发生狼疮性肾炎的BXSB雌性小鼠35只,随机分5组,分别胃饲不同浓度的大黄素混悬液和生理盐水,30天后检测24h尿蛋白浓度和血清抗核抗体(ANA)滴度。
短句来源
     The other four groups were fed with simple normal saline (GroupⅡ), emodin(GroupⅢ),astragaloside (GroupⅣ) and the mixture of both emodin and astragaloside (GroupⅤ) respectively. The proteinuria concentration of 24 h, serumal ANA titers and ICAM 1 expression in glomeruli were detected after 40 days’ feeding.
     Ⅱ~Ⅴ组分别胃饲生理盐水、大黄素、黄芪甲甙和两者混合物 ,40天后检测 2 4h尿蛋白浓度、血清抗核抗体 (ANA )滴度和肾脏细胞间黏附分子 1(ICAM 1)表达水平。
短句来源
     The 24 h proteinuria concentration had a positive correlation with ICAM 1 expression.
     肾小球ICAM 1表达与 2 4h尿蛋白浓度呈正相关。
短句来源
  “proteinuria concentration”译为未确定词的双语例句
     Thirty days later, their proteinuria concentration was detected and expression of intercellular adhesion molecule 1 (ICAM 1) in the glomeruli was analysed by immunohistochemical method of SP (streptavidin/peroxidase) and HPIAS (high resolution pathological image analysis system).
     3 0天后 ,检测每只小鼠的 2 4h尿蛋白含量 ,同时取出肾脏制成切片 ,SP(streptavidin/peroxidase)法检测肾小球细胞间粘附分子 1(ICAM 1)表达水平 ,并用高清晰度彩色病理图文分析系统 (HPIAS)得出定量结果。
短句来源
     Results: Compared with the control group, the proteinuria concentration and expression of ICAM 1 in the glomeruli of the emodin groups decreased (P<0.05).
     结果 : 与生理盐水组相比 ,胃饲大黄素的各组小鼠 2 4h尿蛋白含量和肾小球ICAM 1表达水平均有所下降 (P <0 .0 5 ) ,尿蛋白含量与大黄素剂量 (0~ 6.2 5mg/kg范围内 )呈直线负相关 (P <0 .0 1) ;
短句来源
     The proteinuria concentration showed a positive correlation with expression of ICAM 1 (P<0.001).
     尿蛋白含量与ICAM 1表达水平呈正相关 (P <0 .0 0 1)。
短句来源
     The proteinuria concentration showed a positive correlation with serum ANA tilers (P<0.01).
     血清ANA滴度与大黄素剂量呈负相关(P<0.01);
短句来源
     The emodin dosage (0~6.25 mg/kg) showed negative correlation with the proteinuria concentration and expression of ICAM 1(P<0.001) and even a negative linear correlation with the proteinuria concentration (P<0.01).
     肾小球ICAM 1表达水平与大黄素剂量呈负相关(P <0 .0 0 1) ;
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  相似匹配句对
     proteinuria(-);
     尿蛋白(-);
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     And the concentration
     对HDL、LDL腔内壁面浓度与
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     Proteinuria
     蛋白尿
短句来源
     At the concentration of 10g.
     10g.
短句来源
     The 24 h proteinuria concentration had a positive correlation with ICAM 1 expression.
     肾小球ICAM 1表达与 2 4h尿蛋白浓度呈正相关。
短句来源
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Objective:To study the effect of emodin on the nephritis of BXSB lupus mice and its pharmacological mechanism.Methods:Thirty five BXSB female mice with lupus were divided into five groups, and were fed with emodin in o.9% NaCl solutionin in different dosages. Thirty days later, their proteinuria concentration was detected and expression of intercellular adhesion molecule 1 (ICAM 1) in the glomeruli was analysed by immunohistochemical method of SP (streptavidin/peroxidase) and HPIAS (high resolution...

Objective:To study the effect of emodin on the nephritis of BXSB lupus mice and its pharmacological mechanism.Methods:Thirty five BXSB female mice with lupus were divided into five groups, and were fed with emodin in o.9% NaCl solutionin in different dosages. Thirty days later, their proteinuria concentration was detected and expression of intercellular adhesion molecule 1 (ICAM 1) in the glomeruli was analysed by immunohistochemical method of SP (streptavidin/peroxidase) and HPIAS (high resolution pathological image analysis system). Results: Compared with the control group, the proteinuria concentration and expression of ICAM 1 in the glomeruli of the emodin groups decreased (P<0.05). The emodin dosage (0~6.25 mg/kg) showed negative correlation with the proteinuria concentration and expression of ICAM 1(P<0.001) and even a negative linear correlation with the proteinuria concentration (P<0.01). The proteinuria concentration showed a positive correlation with expression of ICAM 1 (P<0.001). Conclusion :Emodin can down regulate the proteinuria concentration of BXSB lupus mice. The possible immunopharmacological mechanism may depress ICAM 1 expression in the glomeruli.

目的 : 探讨大黄素治疗狼疮性肾炎的作用及其机制。方法 : 取已发生狼疮性肾炎的BXSB雌性小鼠 3 5只 ,分别予以胃饲不同浓度的大黄素混悬液和生理盐水。 3 0天后 ,检测每只小鼠的 2 4h尿蛋白含量 ,同时取出肾脏制成切片 ,SP(streptavidin/peroxidase)法检测肾小球细胞间粘附分子 1(ICAM 1)表达水平 ,并用高清晰度彩色病理图文分析系统 (HPIAS)得出定量结果。结果 : 与生理盐水组相比 ,胃饲大黄素的各组小鼠 2 4h尿蛋白含量和肾小球ICAM 1表达水平均有所下降 (P <0 .0 5 ) ,尿蛋白含量与大黄素剂量 (0~ 6.2 5mg/kg范围内 )呈直线负相关 (P <0 .0 1) ;肾小球ICAM 1表达水平与大黄素剂量呈负相关(P <0 .0 0 1) ;尿蛋白含量与ICAM 1表达水平呈正相关 (P <0 .0 0 1)。结论 : 大黄素能降低BXSB狼疮样小鼠尿蛋白水平 ;其免疫药理学机制可能与下调肾小球ICAM 1表达水平有关

Objective To study the effects of emodin on BXSB mice with lupus nephritis and its pharmacological mechanism. Methods Thirty-five BXSB female mice were divided into 5 groups and were respectively fed with different concentrations of emodin and 0. 9% normal saline (NS). Thirty days later,the proteinuria concentration and serum anti-nuclear antibody (ANA) titers were detected. Results Compared with NS group, the proteinuria concentration and serum ANA titers in the emodin group were all decreased (P<0.05...

Objective To study the effects of emodin on BXSB mice with lupus nephritis and its pharmacological mechanism. Methods Thirty-five BXSB female mice were divided into 5 groups and were respectively fed with different concentrations of emodin and 0. 9% normal saline (NS). Thirty days later,the proteinuria concentration and serum anti-nuclear antibody (ANA) titers were detected. Results Compared with NS group, the proteinuria concentration and serum ANA titers in the emodin group were all decreased (P<0.05 and P<0.01). The emodin dosage (0 to 6.25 mg/kg) showed negative correlations with serum ANA titers (P< 0.01) and even a negative linear correlation with the proteinuria concentration (P<0.01). The proteinuria concentration showed a positive correlation with serum ANA tilers (P<0.01). Conclusion Emodin can down-regulate the proteinuria concentration of BXSB mice. The possible pharmacological mechanims might be related to the reduction of serum ANA titers.

目的 探讨大黄素治疗狼疮性肾炎的作用与机制。方法 已发生狼疮性肾炎的BXSB雌性小鼠35只,随机分5组,分别胃饲不同浓度的大黄素混悬液和生理盐水,30天后检测24h尿蛋白浓度和血清抗核抗体(ANA)滴度。结果 与生理盐水组相比,胃饲大黄素的各组小鼠的24h尿蛋白浓度和血清ANA滴度均有所下降(P<0.05和P<0.01),尿蛋白浓度与大黄素剂量(0~6.25mg/kg)呈直线负相关(P<0.01);血清ANA滴度与大黄素剂量呈负相关(P<0.01);尿蛋白浓度与血清NA滴度呈正相关(P<0.01)。结论 大黄素能降低狼疮样BXSB小鼠尿蛋白水平,其机制可能与降低血清ANA滴度有关。

Objective To evaluate the value of proteinuria determination with H-500 uria terminator and study the possible causes. Methods The proteinuria quantitative determination of 50 urine samples were detected with classical method. The samples were roled into 5 groups which included normal proteinuria, suspected proteinuria, low proteinuria, mid- proteinuria and high proteinuria group according to their proteinuria concentration. A proteinuria qualitative detection of these samples was also done...

Objective To evaluate the value of proteinuria determination with H-500 uria terminator and study the possible causes. Methods The proteinuria quantitative determination of 50 urine samples were detected with classical method. The samples were roled into 5 groups which included normal proteinuria, suspected proteinuria, low proteinuria, mid- proteinuria and high proteinuria group according to their proteinuria concentration. A proteinuria qualitative detection of these samples was also done by Acetic acid-heating and uria terminator. Results (1)The total corresponding rates with theory prediction was 94% in Acetic acid-heating and 82% in uria terminator. Expect normal group, the corresponding rate differences in other groups had statistic significance(P<0.05). (2)The difference between the real proteinuria content and which showed in uria terminator was significant(P<0.05). Conclusions It is showed that uria terminator may make errors in some diseases despite of its prevalent use, especially in the proteinuria content. It should be noted in the clinical evaluation of uria terminator result.

目的以经典的双缩脲蛋白定量法及加热乙酸定性法作参照,评价H-500尿液分析仪对尿蛋白分析的准确性并探讨其影响因素。方法临床新鲜尿标本50份,用双缩脲法作尿蛋白定量,并依经典描述的定性"-±++++++"代表的蛋白浓度范围将其分成相对应的正常组、可疑组、低蛋白组、中蛋白组及高蛋白组,同时用加热乙酸法和机测法作蛋白定性分析。结果①加热乙酸法与理论预测值总符合率为94%,机测法与理论预测值的总符合率为82%,除正常组外,其它组两种方法所测值与理论预测值的符合率的差异均有显著性意义(P<0.05)。②机测法标本含量与实测含量差异有显著性意义(P<0.05)。结论本文资料提示机测法虽然一般可用,但有相当病例误差较大,尤其部分标本机测所标示蛋白浓度与实测浓度相差甚远,在评价机测结果时应引起足够重视。

 
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