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   heterogeneous expression 的翻译结果: 查询用时:0.152秒
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heterogeneous expression
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  异源表达
     Heterogeneous Expression and Protein Purification of the Rabbit Defensin Gene NP-l
     兔防御素基因NP-l的异源表达及蛋白纯化研究
短句来源
     Objective To establish an in vitro heterogeneous expression model of human CYP2E1 (hCYP2E1) cDNA and investigate the effect of the chemical carcinogenic N, N'-dinitrosopiperazine (DNP) on the expression of CYP2E1. Methods Exogenous hCYP2E1 was introduced into the mouse derived NIH3T3 cells using the lipofectamine transfection technique.
     目的 建立人细胞色素P4 5 0 2E1(CYP2E1)cDNA体外异源表达模型 ,观察化学致癌物二亚硝基哌嗪 (N ,N’ dinitrosopiperazine ,DNP)对CYPWE1表达的影响。
短句来源
     In this paper, the heterogeneous expression of recombinant allophycocyanin in Pichia pastoris was completed.
     本文实现了重组别藻蓝蛋白基因在毕赤酵母中的异源表达
短句来源
     The construction of the heterogeneous expression system of EPSPS from S. sclerotiorum provided a basis for inhibitor design of the enzyme.
     核盘菌EPSPS异源表达系统的建立为该酶的抑制剂设计奠定了基础.
短句来源
  “heterogeneous expression”译为未确定词的双语例句
     Objective To study gene mutation of E-cadherin and β-catenin during the progression of gastric carcinoma, which related together with there immunohistochemical detection to explore the alterations and their significance of the heterogeneous expression of E-cadherin and β-catenin in the level of gene products.
     目的 认识E-钙粘蛋白(E-cadherin)及β-环连蛋白(β-catenin)在胃癌演进过程中基因的突变,结合其免疫组化检测了解E-cadherin和β-catenin在基因产物水平异质化表达的改变和意义。
短句来源
     In addition, the heterogeneous expression of FN mRNA(on 5.0 kb position) was found in tumor tissues from 5 cases of HCC with intrahepatic metastasis.
     5例伴肝内转移的HCC癌组织FNmRNA呈异质性表达(5.0kb位置)。
短句来源
     In addition, the heterogeneous expression of FN mRNA was found in 5 cases of HCC with intrahepatic metastasis.
     5例伴肝内转移的HCC癌组织中FNmRNA呈异质性表达。
短句来源
     Recombinant human hepatopoietin,expressed in the strain pBV-hHPO/DH5α,existed as two forms of molecules. The two forms of molecules were all reactive with anti-hHPO monoclonal antibody. Inspection of the nucleotide sequence of the plasmid containing the hHPO gene suggested that the heterogeneous expression of hHPO maybe caused by a readthrough of the termination codon TAG.
     在工程菌pBV hHPO DH5α中表达的人肝细胞生成素 (hHPO)以两种分子形式存在 ,经分析可能是由于表达质粒中hHPO基因的终止密码子TAG的通读造成的。
短句来源
     The Recombination and Heterogeneous Expression of an Anti-tumor Gene in the Chloroplast of Chlamydomonas Reinhardtii
     一种抗肿瘤蛋白基因在衣藻叶绿体中的重组与表达
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  相似匹配句对
     The expression
     COX-2、VEGF-C mRNA的表达与肿瘤TNM
短句来源
     The expression
     在交界瘤、良性瘤中无表达。
短句来源
     It is heterogeneous.
     (三)、异质语转和同质语转的意义
短句来源
     B.heterogeneous;
     B.质地不均匀;
短句来源
     3 The expression of VEGF and b FGF was heterogeneous.
     3VEGF,b FGF在不同个体的表达具有异质性。
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  heterogeneous expression
coliβ galactosidase indicates heterogeneous expression of the
      
Single-cell quantitation of binding of monoclonal BLMRL-HMFG-Mc5 to three breast tumor cell lines using a Microscope Spectrum Analyzer and indirect immunofluorescence revealed a heterogeneous expression.
      
Heterogeneous expression of two oncodevelopmental antigens, CEA and SSEA-1, in colorectal cancer
      
Using immunocytochemistry and cell-specific monoclonal antibodies, we identified heterogeneous expression of goblet, mucous, and serous cell markers among the cell lines.
      
Heterogeneous expression of CD55 or CD59 was observed in 8 (11%) of 71 patients and 4 (6%) of 71 patients, respectively.
      
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The incidence of large-bowel cancer among the Chinese young people is higher than that of Western young men. The present study was designed to compare the status of four lectin-binding expressions of primary lesions (PL)/lymph node metastatic lesions (LML) of rectal cancer at stage Ⅲ or Ⅳ in the young (≤30 years) with those in the old (≥60 years) by the avidin-biotin-peroxidase technique. The heterogeneous expressions of PNA, UEA-1, DBA and WGA receptors of PL/LML of rectal cancers in the young and...

The incidence of large-bowel cancer among the Chinese young people is higher than that of Western young men. The present study was designed to compare the status of four lectin-binding expressions of primary lesions (PL)/lymph node metastatic lesions (LML) of rectal cancer at stage Ⅲ or Ⅳ in the young (≤30 years) with those in the old (≥60 years) by the avidin-biotin-peroxidase technique. The heterogeneous expressions of PNA, UEA-1, DBA and WGA receptors of PL/LML of rectal cancers in the young and old groups were demonstrated. The positive results of PNA-binding was higher in the young group than in the old group, while the unreactive results of PNA-binding in PL/LML of the old group was significantly higher than that of the young group. The above results suggest that the heterogeneity of glycosylation in rectal cancer exists in the same way as histologic appearance. The higher PNA binding expression of rectal cancer in the young is probably related to their biological behavior character and poor prognosis, which remains to be further identified.

我国青年人大肠癌发病率明显地高于欧美国家,而且预后较差。本文用凝集素组化法比较了青年人和老年人Ⅲ期或Ⅳ期直肠癌原发灶及淋巴结转移灶四种凝集素受体表达状况。结果显示,青年组和老年组直肠癌原发灶及转移灶PNA,UEA-1、DBA和WGA受体呈分布不均一性。青年组直肠癌原发灶和(或)转移灶PNA受体阳性显著高于老年组。提示直肠癌在糖基化功能方面与组织形态异质性相似亦存在不均一性,青年人直肠癌PNA受体阳性高于老年人可能是青年人大肠癌生物学行为特征之一,同青年人直肠癌预后差可能有关。但有待于进一步研究。

The expression of ras P21 and erbB 2 P185 in human gastric cancer, adjacent to cancer and normal mucosa were examined by using monoclonal antibody EB2411 to a synthetic peptide reflecting amino acid position 56~64 of ras P21 protein and multiclonal antibody of P185 with immunohistochemical technique.The results showed that the expression rates of P21 in the normal gastric mucosa, adjacent to cancer and gastric cancer were 13.3%, 79.3%...

The expression of ras P21 and erbB 2 P185 in human gastric cancer, adjacent to cancer and normal mucosa were examined by using monoclonal antibody EB2411 to a synthetic peptide reflecting amino acid position 56~64 of ras P21 protein and multiclonal antibody of P185 with immunohistochemical technique.The results showed that the expression rates of P21 in the normal gastric mucosa, adjacent to cancer and gastric cancer were 13.3%, 79.3% and 68.9% respectively. The positive cells in gastric cancer, adjacent to cancer and normal mucosa were (147.22± 39.96) mm -2 ,(21.89±10.38)mm -2 and (3.96±1.52) mm -2 respectively. There was significant difference among the three kinds of tissues. However, there was no obvious relation between the expression of P21 and the differentiation types of gastric cancer ( P <0.05), and it demonstrated a heterogeneous expression in gastric cancer. The expression of P185 erbB 2 was similar to that of P21 ras in gastric cancer, adjacent to cancer and normal ti ssue. But it was significantly enhanced in well differentiated gastric cancer as compared with moderately and poorly differentiated gastric cancers. The expression of P185 was increased in clinic stages Ⅲ and Ⅳ more than that in stages Ⅰ and Ⅱ. The results indicated that both the expression of P21 and P185 were enhanced in cancerous tissues. There was an increased expression of P185 in advanced and well differentiated gastric cancer, while P21 enhanced the expression in early gastric cancers, and there was no obvious correlation with the differentiated types of gastric cancers.

应用ras癌基因产物P21蛋白一段氨基酸序列的合成肽的单克隆抗体EB2411和erbB2癌基因产物P185抗体,对人胃癌、癌旁和正常组织中ras和erbB2的表达进行免疫组化研究,结果:P21在正常、癌旁和癌组织的阳性率分别为133%、793%和689%;阳性细胞数分别为(40±15),(219±104)和(1472±400)mm-2,三者之间呈显著性差异(P<001)。P21的表达与肿瘤的分化类型无显著性差异。早期胃癌(病变局限于粘膜层和粘膜下层)P21表达高于进展期胃癌。高分化腺癌中P185IR阳性细胞数明显多于中、低分化癌。Ⅰ、Ⅱ期胃癌P185阳性细胞数较少,而Ⅲ、Ⅳ期显著增多。提示:P21参与胃癌的早期发生,而P185与胃癌的晚期发展有关,并参与胃癌细胞的分化调节。

The expression of integrin α5 、β1 subunit and FN mRNA was detected by Northern blot in 15 cases of HCC tissues, 5 cases of paracancerous cirrhotic liver tissues and 3 cases of normal liver tissues. The levels of expression of integrin α5 , β1 and FN mRNA in poorlydifferentiated HCC were decreased or absent in contrast to the paracancerous liver cirrhotic/normal liver tissues and the welldifferentiated HCC(P<0.01, respectively). In all cases of HCC tested,the expression of integrin α5, β1 and FN mRNA was...

The expression of integrin α5 、β1 subunit and FN mRNA was detected by Northern blot in 15 cases of HCC tissues, 5 cases of paracancerous cirrhotic liver tissues and 3 cases of normal liver tissues. The levels of expression of integrin α5 , β1 and FN mRNA in poorlydifferentiated HCC were decreased or absent in contrast to the paracancerous liver cirrhotic/normal liver tissues and the welldifferentiated HCC(P<0.01, respectively). In all cases of HCC tested,the expression of integrin α5, β1 and FN mRNA was lower in 8 cases of HCC with focal invasion and/or intrahepatic metastasis than that in the cases without invasion or metastasis(P<0.05). In addition, the heterogeneous expression of FN mRNA(on 5.0 kb position) was found in tumor tissues from 5 cases of HCC with intrahepatic metastasis. The results indicated that the altered expression of integrin α5, β1 and FN proteins at gene transcription level is well associated with the cell differentiation, invasion and metastasis of HCC. The unusual FN mRNA and its encoed FN protein might have some biologic significance in the process of HCC metastasis.

用Northern印迹杂交对15份人肝细胞癌(HCC)、5例癌旁肝硬变和3例正常肝组织标本中整合素α5、β1亚基和纤维连接蛋白(FN)mRNA表达作杂交分析。结果:低分化HCC癌组织中整合素α5、β1亚基和FNmRNA表达水平明显低于高分化HCC及癌旁和正常肝组织(P<0.01);HCC伴肝内浸润和(或)转移组癌组织内3种mRNA水平较无浸润转移组低,差异有显著性意义(P<0.05);5例伴肝内转移的HCC癌组织FNmRNA呈异质性表达(5.0kb位置)。提示:FN及其受体整合素α5、β1基因转录水平的改变与HCC细胞分化、浸润和转移密切相关;异质性FNmRNA及其编码的FN蛋白可能在HCC转移中有意义。

 
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