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tumor strains
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  肿瘤活性的菌株
     Objective To screen the anti fungi and anti tumor strains from the soil fungi.
     目的从土壤真菌中筛选有抗真菌、抗肿瘤活性的菌株
短句来源
  肿瘤活性菌株
     Conclusions The Pyricularia oryzae was a good primary model for screening anti fungi and anti tumor strains.
     结论稻瘟霉是良好的筛选抗真菌、抗肿瘤活性菌株的初筛模型
短句来源
  瘤株
     ISOLATION PURIFICATION AND BIOLOGICAL PROPERTY OF LEUKEMIA VIRUS FROM L_(6565) AND SRS TUMOR STRAINS
     L_(6565)和SRS瘤株的白血病病毒分离提纯及其生物学特性研究
短句来源
     Based on the establishment of different models of cloned tumor strains of implanted hepatocellular carcinoma in nude mice,the expression of H-ras,P53 and C-erbB-2 gene proteins in tumor tissues and the expression of AFP,HBsAg and CEA were studied using immunohistochemical method.
     在建立不同克隆化肝癌裸鼠移植瘤株模型的基础上,用ABC免疫酶标记法研究了癌基因H-ras、P53、C-erbB-2蛋白在不同克隆化肝癌裸鼠移植模型瘤组织中的表达,同时也检测了AFP、CEA、HBsAg等的表达。
短句来源
     METHOD 90 Kunming mice were divided randomly into 9 groups and injected with S180 tumor strains.
     方法 将 90只昆明小鼠据体重随机分成 9组 ,腹腔接种S180 瘤株 ,化疗采用CTX ,针灸处理以灸和温针灸为主 ,穴位采用足三里、命门和大椎。
短句来源
     A375 S2,T98G and HeLa tumor strains were used for anti tumor experiment in vitro.
     离体抗肿瘤实验用 3种瘤株 :A375 - S2、T98G 和 He La。
短句来源
     The differences of tumor progression among these 3 transplantable tumor strains appear to suggest that the mechanisms involved in the progression of these 3 tumor strains were somewhat different, and it was appreciable to investigate this problem further.
     三个瘤株演进的这些差异似乎表明在引起演进的机制上存在着差别,这是值得进一步探讨的问题。
短句来源
  “tumor strains”译为未确定词的双语例句
     A DYNAMIC RESEARCH ON THE ACTIVITY OF ALKALINE PHOSPHATASE IN THE DEVELOPING PROCESS OF TWO TUMOR STRAINS OF EXPERIMENTAL LEUKEMIA IN MICE(L7710 AND L7711)
     可移植性小鼠淋巴细胞性白血病L7710及L7711发展过程中碱性磷酸酶活性的动态观察
短句来源
     Objective: To study the effect of ginsenoside Rh 1 and Rg 1 on the experimental tumor strains in vivo and in vitro.
     目的 :研究人参皂苷 Rh1及其前体 Rg1的整体及离体抗肿瘤作用。
短句来源
     In vitro, the antitumor effects of 6 alkaloids isolated from the seed of Sophora viciifolia on 11 kinds of human being tumor strains has been reported.
     报道了从白刺花种子中分得的6种生物碱单体对人体11种癌瘤株体外抑瘤作用。
短句来源
     Changes in blood coagulation system and histopathological examination were investigated simultaneously The results showed that the onset of DIC realted to the rapid tumor reduction,blood coagulation factors changed significantly in the experiment group of AH109A,and the occurrence of DIC was dependent on the tumor strains。
     结果发现:移植AH109A细胞的实验组大鼠,在疗效显著、肿瘤迅速缩小的同时,出现血小板减少、纤维蛋白原增加、凝血酶原时间延长; 而AH272实验组及其他对照组动物,则无明显改变。
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  tumor strains
Comparative Action of Salsoline, Salsolidine, and Related Compounds on KML Tissue Culture and Animal Tumor Strains
      
Effect of Ephedrine and Its Derivatives in KML Cell Culture and on Tumor Strains of Animals
      
Platelets of intact mice and mice with tumors posses cytotoxic activity towards autologous and allogenic tumor strains.
      
A total of 19 human tumor strains transplanted to athymic mice and rats are tested for their sensitivity to antineoplastic agents of different classes including alkylating compounds, platinum complexes, and nitroso compounds.
      
Sensitivity to antineoplastic agents of human tumor strains in immunodeficient mice
      
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The purpose of the present experiment was to observe the morphological characteristics and invasiveness of a transplantable cancer NO 27 (U 27) after serial passages about 20 years. The results were as follows: The morphological characteristics of this tumor strain was low-differentiated carcinoma which were demonstrated by light microscopy and transmission electron microscopy. In the cytoplasm the single irregular distribution of the tensile fibrils and some semi-desmosome between adjacent cells were...

The purpose of the present experiment was to observe the morphological characteristics and invasiveness of a transplantable cancer NO 27 (U 27) after serial passages about 20 years. The results were as follows: The morphological characteristics of this tumor strain was low-differentiated carcinoma which were demonstrated by light microscopy and transmission electron microscopy. In the cytoplasm the single irregular distribution of the tensile fibrils and some semi-desmosome between adjacent cells were discovered by transmission electron microscopy. Two types of cancer cells were observed on the surface of the cancer nest by scanning electron microcopy:Ⅰ), There were many microvilli on the surface of the first type cancer cells; 2). The surface of the cancer cells of the second type were more flat sometimes with single small blebs. Many cancer cells had been released from cancer cell clump after 3 days of intramuscular implantation. Later they actively invaded into the spaces between muscle fibers in the form of amebae. Some cancer cells stretched out their filopodia directly in contact with target cells. The degenerative and atrophic changes of muscle tissue appeared in the invasive area of cancer cells. Finally these changes were leading to the disappearance of the entire structure of the muscle with the replacement by cancer tissues.

本文目的是检查可移植性子宫颈癌(U27),经二十多年传代后形态的改变特征及其侵袭能力。组织学和透射电镜检查证明本瘤株已变为低分化的上皮癌;电镜检查胞浆内仅查见少数张力原纤维,细胞连接仅见半桥粒及类桥样结构,未见典型鳞状上皮癌的特征。扫描电镜检查可见癌细胞表面有两种主要表现类型:一种带有大量微绒毛;另一种表面比较光滑仅有少量泡状突起。肌肉内小块移植后3天,即见大量癌细胞脱离癌实体,向肌肉纤维之间活跃侵袭,侵袭方式主要沿肌细胞之间的自然间隙连续侵入,也见沿肌细胞表面呈阿米巴样运动,有的癌细胞表面伸出不同突起与靶细胞直接连接,有的癌细胞伸出丝状伪足,用其分叉的末端紧紧抓住靶细胞表面。在癌组织侵袭之处可见肌细胞变性、进而萎缩,最终可完全被癌细胞所代替。

Changes in histomorphology and biologic behavior during the course of the establishing and retaining of 3 transplantable strains of mammary carcinoma (Ca759, Ca761, Ca763) in syngenic 615 mice were observed. Through analysing and comparing the changes of these 3 tumor strains during successive passages, it was found that the common features of tumor Progression were: tending to become simplified in histological structure,increased in the number of mitosis, and shortening of both the latent period...

Changes in histomorphology and biologic behavior during the course of the establishing and retaining of 3 transplantable strains of mammary carcinoma (Ca759, Ca761, Ca763) in syngenic 615 mice were observed. Through analysing and comparing the changes of these 3 tumor strains during successive passages, it was found that the common features of tumor Progression were: tending to become simplified in histological structure,increased in the number of mitosis, and shortening of both the latent period of tumor growth and the survival time of hosts. But there were some differences in the time of occurrence, the rapidity and the histological appearance of progression among Ca759, Ca761 and Ca763. In Ca759 through 140 transplant passages, and in Ca761 through 79 transplant passages, simplification of histologic structures progressively developed, while in Ca763, after 5 transplant passages the latent period of tumor growth and the survival time of the hosts were shortened abruptly, and its histologic patterns were conspicuously different from those of the primary and the 4th generation of tumor transplantation. In Ca761, since the 80th generation onwards, the survival time of the hosts were shortened abruptly, and also the mitotic number of tumor cells was increased. The differences of tumor progression among these 3 transplantable tumor strains appear to suggest that the mechanisms involved in the progression of these 3 tumor strains were somewhat different, and it was appreciable to investigate this problem further.

观察了三株615系小鼠可移植性乳癌(Ca759、Ca761、Ca763)在建株和保种过程中肿瘤组织形态学与生物学行为方面的变化。分析比较肿瘤的演进过程,其共同特点为:瘤组织结构趋向简化,核分裂数增多,接种后肿瘤生长的潜伏期和宿主生存期缩短。但是这些变化发生的迟早、进展快慢及形态学表现等,在三个瘤株之间也有某些差异。Ca759自第1代至140代,Ca761自第1至79代,传代过程组织结构简化均呈渐进性。Ca763移植至第5代后肿瘤潜伏期与宿主存活期急剧缩短,组织学图象与原发瘤及第4代有显著差别。Ca761自80代以后宿主存活期突然缩短,瘤细胞核分裂数增多。三个瘤株演进的这些差异似乎表明在引起演进的机制上存在着差别,这是值得进一步探讨的问题。

After screening,the authors established a mouse model of pathomorphologically special,transplantable mammary spindle cell carcinoma SCC 891 in BALB/c mice.After 48 passages in 2.5 years,the growth of the tumor strain became stable with a 100% transplantibility.Its growth was quite active without observable spontaneous regression.The mean life span of the host mouse was 35.2±7.3 days.BALB/c mice of both sexes and of any age were susceptable to the carcinoma,and the carcinoma was sensitive to various anticancer...

After screening,the authors established a mouse model of pathomorphologically special,transplantable mammary spindle cell carcinoma SCC 891 in BALB/c mice.After 48 passages in 2.5 years,the growth of the tumor strain became stable with a 100% transplantibility.Its growth was quite active without observable spontaneous regression.The mean life span of the host mouse was 35.2±7.3 days.BALB/c mice of both sexes and of any age were susceptable to the carcinoma,and the carcinoma was sensitive to various anticancer drugs.

作者选择性地利用BALB/c小鼠建立了一株病理形态特殊的可移植性乳腺梭形细胞癌模型SCC891。经过2.5年48代的移植,瘤株的生长特性已经稳定。移植瘤的发生率100%,生长速度快,不出现肿瘤自然消退现象,宿主存活时间为35.2±7.3 d,在BALB/c小鼠同系内移植不受性别及年龄的限制。瘤株对抗癌药的敏感性广泛。

 
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