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blastic cells
相关语句
  幼稚细胞
     The LDH and HBDH are positive correlation to the blastic cells in the peripheral blood.
     LDH和HBDH值与外周血幼稚细胞数呈正相关。
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  “blastic cells”译为未确定词的双语例句
     The hypermethylation of CT gene might be associated with the transformation to increase blastic cells in MDS and might have prognostic value in MDS.
     结论 :CT基因高度甲基化较广泛地存在于ANLL、MDS和CML急变期 ,是ANLL和MDS患者白血病细胞克隆以及CML进展和急变的一个共同的分子标志 ,而且CT基因高度甲基化与MDS的转归和预后可能有一定关系
短句来源
     Result:The BCL 2 gene expression level was no correlation with the age, sex, lymphadenopathy, hepatomegaly, splenomegaly, bleeding, lactic dehydrogenase,subtype of leukemia and newly diagnosed group or relapsed refractory lekemia group. But it was positively associated with leukemic blastic cells. In addition to 7 acute promyelocytic leukemia patients, the complete remission (CR) rate in high BCL 2 expression group were lower than that in low BCL 2 expression group.
     结果 :BCL 2基因的表达水平与患者的年龄、性别、淋巴结肿大、肝脾肿大、出血、生化乳酸脱氢酶LDH、白血病分型及初治或复发难治等因素无关 ,但与患者骨髓中原幼细胞数呈正相关 ,除 7例急性早幼粒细胞白血病患者外 ,BCL 2基因高表达患者完全缓解率 (CR)低于低表达者。
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  相似匹配句对
     U cells.
     Li/TK细胞3d,即可将其杀死.
短句来源
     The whole cells of R.
     直接将霉菌R.
短句来源
     The LDH and HBDH are positive correlation to the blastic cells in the peripheral blood.
     LDH和HBDH值与外周血幼稚细胞数呈正相关。
短句来源
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  blastic cells
(6) Prohemocytes, blastic cells which are one of the stem cells of hemocytes, are very few in number in each species investigated.
      
Thus, polymorphic immunocytoma is a follicle centre cell lymphoma with differentiation into plasma cells rather than a lymphoplasmacytoid immunocytoma with blastic cells.
      
Although the presence of multinucleated and blastic cells associated with a low-grade brain neoplasm is unusual, recognition of hematopoietic lineages allows EMH to be readily identified.
      
Recruitment was not significantly different in patients with CD34+ leukemic cells at the time of initial diagnosis when compared to that of those presenting with CD34- blastic cells.
      
We report a case of a boy with acute lymphoblastic leukemia expressing granular inclusions in the cytoplasm of blastic cells.
      
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Short-term culture of PHA(phytohemag-glutinin) stimulated human lymphocyte iswidely used for analysis of cell cycle kineticsand cytogenetics.The same technique also haswidespread application to detect chromosomedamage caused by exogenous mutagen and im-mune response of blood.A deep understand-ing of lymphocyte proliferation is essentialfor these studies.In present experiment,acombination of radioautography to determinewhen a cell synthesized DNA,and cytopho-tometry to measure the cellular DNA content,was carried...

Short-term culture of PHA(phytohemag-glutinin) stimulated human lymphocyte iswidely used for analysis of cell cycle kineticsand cytogenetics.The same technique also haswidespread application to detect chromosomedamage caused by exogenous mutagen and im-mune response of blood.A deep understand-ing of lymphocyte proliferation is essentialfor these studies.In present experiment,acombination of radioautography to determinewhen a cell synthesized DNA,and cytopho-tometry to measure the cellular DNA content,was carried out to characterize the blastogenicresponse of lymphocyte. Fresh human peripheral blood was addedto RPMI 1640 medium containing fetal calfserum and PHA.When cultured at 37℃ for72 hours,lymphocytes are stimulated andtransform into blastic cells which then proli-ferate.Before the cells were harvested,0.5μCi/ml 3~H-TdR were offered into cultures.After removal of red cells by hypotonic shocktreatment,the remaining lymphocytes werecollected and smeared.Radioautographyic pro-cedures and Feulgen reaction were carried onthe preparations sequently.The percentage oflymphocytes labeled by silver grains (S) firstcounted,then Feulgen density of unlabeledcells (G_1) random selected in the same slidewas measured cytophotometrically.In orderto check the technical error in various prepa-rations,chick erythrocytes were added on eachslide to provide an internal staining standard.The relative DNA content (24.06) of prome-taphase (4 C) of lymphocyte was used as areference standard for ploidy.Six groups of blood cultures were treated with isotope for 0,0.5,2,4,7 and 17 hours,the labellingindexes of activated lymphocytes in respectivepreparations have 0%,1.90%,9.15%,13.40%,15.01% and 30.13%.In addition,Feulgen density of unlabeled cells in same sli-des reach 15.42 (DI=1.28),15.45 (DI=1.28),14.88(DI=1.24),13.77(DI=1.14),13.20(DI=1.10) and 12.94(DI=1.08) re-spectively.Even treated with isotope for onecell generation time (17 h),there are alwaysa considerable number of unlabeled lympho-cytes to exist in 2 C —4 C DNA range.Obvious-ly,these intermediate DNA value are notdue to nuclei being in S phase at the time.It would like to propose that DNA synthesisin S phase of lymphocytes may be not contin-uous. On the other hand,attempt was made tocorrelate DNA synthesis with DNA contentat single cell level.141 labeled lymphocyteswere selected at random on radioautographicslides,their coordination were recorded inmicrophotographic films for relocation.First,DNA newly synthesized in individual cell inS phase was determined by quantitative 3~H-TdR-radioautography.Optical density of silvergrains of labeled cells (S) were measured intransmitted light at 546 nm (mean 28.82).Secondly,after dissolving silver grains in so-lutions of potassium ferric cyanide and sodiumthiosulfate,the same slides were Feulgen stain-ed.DNA content of individual preselectednucleus was measured at 546 nm (mean 16.27,DI=1.35).We found that the labeled cellsdisplay a great difference in the number ofsilver grains,these cells always possess 2C—4C DNA value.Some concomittant increaseis also observed in the mean value of DNAsynthesis during S phase.These findings me-rit further attention.

体外培养受PHA刺激的人淋巴细胞经~3H-TdR参入0、0.5、2、4、7和17小时后,放射自显术表明标记指数为0%、1.90%、9.15%、13.14%、15.01%和30.13%。未标记细胞的福尔根光密度为15.42、15.45、14.88、13.77、13.20和12.94。DNA分布直方图显示部分未标记细胞介于2C—4C,表明S期细胞的DNA合成可能是不连续的。对同位素参入17小时的标记细胞连续进行两项测量表明,这些细胞的银粒光密度相差悬殊,但其DNA含量均为2C—4C。细胞的DNA合成率随其DNA含量而增高。

Leukemic Patients who have gained clinical complete remi-ssion(CR)after chemotherapy usually showed significant depression of bonemarrow on general scintigraphs.Three CR cases of acute lymphoblastic leu-kemia are reported as an exception.It has been found that some undepre-ssed active bone marrow foci were present in the peripheral bone marrowcavity.These foci were verified by bone marrow puncture as focal residueleukemia due to the presence of more than 5% lymphoblastic cells in thefoci while the bone...

Leukemic Patients who have gained clinical complete remi-ssion(CR)after chemotherapy usually showed significant depression of bonemarrow on general scintigraphs.Three CR cases of acute lymphoblastic leu-kemia are reported as an exception.It has been found that some undepre-ssed active bone marrow foci were present in the peripheral bone marrowcavity.These foci were verified by bone marrow puncture as focal residueleukemia due to the presence of more than 5% lymphoblastic cells in thefoci while the bone marrow at routine puncture sites showed no lympho-blastic cell at all.It is obvious that these foci are quite different fromthose defined by the previous concept on residue leakemia which is gene-ralized dissemination of leuk(?)m(?)oughout the body.It isbelieved that this is the first report on such(?)residue leukemia so far.The characteristics of focal(?)esidue(?)one marrow scintigraphsare 1.most of these foci are(?)pheral bone marrow ca-vity particularly near the epiphysis of the kne(?)joint,2.Its distributionis symmetrical,3.the level of(?)identical,4.most of thevictims are young in age.This finding seems to be valuable for creating standardization of CR,facilitating the decision making in the treatment of leukemia and improv-ing its prognosis.

3例急性淋巴细胞性白血病患者获得完全缓解(CR)后,外周骨髓仍存在未被抑制的局限性活性骨髓灶,骨髓细胞学检查表明常规穿刺部位的骨髓均呈CR髓像,但在局限性活性骨髓灶含有超过5%的幼淋白血病细胞,确定为骨髓残余白血病病灶,这与通常所指弥散分布于全身的白血病细胞而言的残余白血病系两个不同的概念。这是迄今为止首次发现的局限性骨髓残余病灶。这将对探讨白血病缓解的标准,制订治疗方案及判定预后具有意义。

It has been shown that IL-3 is able to stimulate the proliferation and differentiation of hemopoieticstem cell in vitro. In this paper, We have established an human acute myeloblastic leukemia cell lineinduced by IL-3, It has been studicd and observed by cytochemistry, immunoelectron microscopy,scaning electron microscopy, surface markers and chromosome analysis. The results indicate that IL-3is able to stimulate the proliferation of AML cells in vitro. These AML cells still possesse...

It has been shown that IL-3 is able to stimulate the proliferation and differentiation of hemopoieticstem cell in vitro. In this paper, We have established an human acute myeloblastic leukemia cell lineinduced by IL-3, It has been studicd and observed by cytochemistry, immunoelectron microscopy,scaning electron microscopy, surface markers and chromosome analysis. The results indicate that IL-3is able to stimulate the proliferation of AML cells in vitro. These AML cells still possesse thecharacters of blastic cell in morphology, cytochemistry and cell surface markers.

目前研究认为,白细胞介素3(IL—3)可以促进骨髓多能干细胞的分化和增殖。本文将一例急性粒细胞白血病患者外周血白血病细胞进行培养,传代70代以上,并对其进行了形态学观察、细胞化学和免疫细胞化学染色、细胞表面标记和染色体分析。结果表明,rIL—3在体外培养中对原始粒细胞确有促进其增殖作用。

 
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