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inhibit concentration
相关语句
  抑制浓度
     The limit of detection was 0.6 ng/ml, 50% inhibit concentration was 3.0 ng/ml. When the spiked concentrations of ZER were 10 ng/ml, 21 ng/ml and (35 ng/ml), the recovery range was from 70.0% to 116%, the coefficient range of variation was from 6.0% to 15.9%.
     本方法的最低检测限为 0 .6 ng/ml,5 0 %抑制浓度为 3.0 ng/ml,以 10、2 1和 35 ng/ml浓度添加空白牛尿 ,回收率在 70 .0 %~ 116 .0 %之间 ,变异系数在 6 .0 %~ 15 .9%之间。
短句来源
  “inhibit concentration”译为未确定词的双语例句
     And the half of inhibit concentration (IC50) of total flavonoids on leukemia L1210 cells was 7.756ug·ml-1. These results suggest that the total flavonoids (TF) from T. Kirilowii have higher anti-tumor activity to the L1210 cells than the HCC and Hep-G2 cells.
     说明狗舌草总黄酮对L_(1210)有一定抑制作用,对肝癌细胞HCC及Hep-G_2作用不明显。
短句来源
     Then, we compared the sensitivity of MCS to doxorubicin ( DOX ) with MCC at the level before and after blocking the activity of NF kappa B by adding NF kappa B inhibitor SN50. MCS was more resistant to DOX and 50% inhibit concentration ( IC50 ) increased
     接着,检测了MCS与MCC在阻断NF kappa B前后化疗药物敏感性的变化。 发现MCS对阿霉素(DOX)的敏感性显著下降。
短句来源
     The half inhibit concentration(IC5o) of Chinese hamster ovary(CHO) cells which transinfect 58bp deleted pol B wild pol B and empty plasmid by cisplatin were detected by MTT.
     并在倒置显微镜下观察两种细胞形态变化,流式细胞仪检测两种细胞的周期分布,提取两种细胞的核蛋白,用Westem蛋白电泳测定两种细胞内的DNApolp表达水平。 将分别转染58bP缺失型polp质粒和野生型polp质粒的CHO细胞与转染空质粒的CHo细胞用MTT法测定顺铂对这三种细胞的抑制率,计算出IC50。
短句来源
     The broth dilution method was used for MIC (minimum inhibit concentration) and MBC (minimum bactericidal concentration) determining.
     实验采用试管系列稀释法,测得各药物对不同细菌的最低抑菌浓度和最低杀菌浓度。
短句来源
     Selective anti virus drug adding 100 fold of TICD50 virus dose infected DBT cell as positive results by protesting lower 50% CPE, and tested drugs lowest virus inhibit concentration.
     以100倍的TCID50病毒量感染细胞同时加不同稀释度的药物,在同一条件下,动态观察不同时间的细胞的CPE变化。 以能保护CPE<50%为阳性。
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  相似匹配句对
     And the concentration
     对HDL、LDL腔内壁面浓度与
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     Aluminum in appropriate concentration might inhibit synaptic transmission.
     表明一定剂量的铝具有抑制CA3区PS波幅的作用,铝可能是抑制CA3区的突触传递过程。
短句来源
     (2) concentration;
     2.集中性;
短句来源
     inhibit the apoptosis;
     抑制细胞凋亡;
短句来源
     240ppm F~- concentration can inhibit S.mutans from growth complctely.
     240ppm氟离子能完全抑制细菌生长。
短句来源
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The action of aureomycin on the respiration of Escherichia coli under different conditions was studied. Our results show that the respiration of Escherichia coli in ordinary broth or in media containing glucose together with some nitrogenous substance such as casein hydrolysate, alanine, aspartate, glutamate, glycine or ammonium sulfate, could be inhibited by aureomycin of minimal growth inhibiting concentration, namely 2.5 μg/ml. In the last case, the uptake of ammonium-nitrogen by the bacteria...

The action of aureomycin on the respiration of Escherichia coli under different conditions was studied. Our results show that the respiration of Escherichia coli in ordinary broth or in media containing glucose together with some nitrogenous substance such as casein hydrolysate, alanine, aspartate, glutamate, glycine or ammonium sulfate, could be inhibited by aureomycin of minimal growth inhibiting concentration, namely 2.5 μg/ml. In the last case, the uptake of ammonium-nitrogen by the bacteria was also diminished. Aureomycin of concentrations lower than 100 μg/ml gave no significant effect on the oxygen consumption of the bacteria in a medium containing glucose and phosphate buffer only. Similar results were obtained with pyruvate substituted for glucose and with glutamate as nitrogen source, while with pyruvate alone the oxidation was only slightly depressed by aureomycin (2.5 μg/ml). Malate and acetate oxidations were not inhibited by such low concentration of the antibiotic. In control experiments addition of any of the above mentioned nitrogenous substances to the medium markedly increased the rate of the respiration over that observed for glucose or pyruvate alone, and this increase with the exception of glutamate could not be accounted for by the additional oxidation of the nitrogen containing substrates. In presence of 2.5 μg/ml of aureomycin, this enhancing action of the nitrogenous compounds was strongly depressed. The observed inhibition in case of the substrate mixture cannot be due to the action of the drug on the oxidation of the individual substrates, but is due to processes involving the combined metabolism of glucose (pyruvate) and any one of the nitrogenous compounds. From the fact that the inhibition is clearly noticeable within 15 minutes after the addition of aureomycin and can be observed under conditions in which growth does not take place, as judged from the respiration, it is suggested that aureomycin can inhibit some processes concerned with the oxidative nitrogen metabolism, preceding cell division, of Escherichia coil.

實驗結果表明最低制菌濃度的金黴素可以顯著抑制大腸桿菌在含有葡萄糖和某些合氮物如酪朊水解物、丙氨酸、門冬氨酸、谷氨酸、甘氨酸或硫酸銨的培養基中的呼吸,也抑制了氨氮的同化。在以丙酮酸和谷氨酸作底質時有同樣的現象。以上述含氮物中的任何一種加於大腸桿菌的葡萄糖磷酸鹽緩衝劑的懸浮液中,可以有力地提高其呼吸率,比在單獨葡萄糖中的要高得多。2.5微克/毫升的金黴素可以強烈地抑制這種提高作用。這種觀察到的抑制並不是由於個別底質分别受到抑制的結果。本文討論了金黴素抑制大腸桿菌呼吸的作用機構和可能的幾種解釋,並指出這種作用可能是由於金黴素抑制了包括碳水化物和含氮物在内的某個或某些聯合代謝過程。

(1)The uptake of sulfanilate by wheat leaves has been investigated.It confirms thefact that the process follows Fick's law of diffusion.(2)For the translocation of sulfanilate in wheat leaves,the types of diffusion curvesof“base to tip”were found to be different from those of“tip to base”.(3)The measurements of Q_(10) and Q_5 indicates that within the physiological range ofwheat,the temperature effect on absorption can be calculated exactly by Einstein's equation.An empirical formula which enables one to obtain...

(1)The uptake of sulfanilate by wheat leaves has been investigated.It confirms thefact that the process follows Fick's law of diffusion.(2)For the translocation of sulfanilate in wheat leaves,the types of diffusion curvesof“base to tip”were found to be different from those of“tip to base”.(3)The measurements of Q_(10) and Q_5 indicates that within the physiological range ofwheat,the temperature effect on absorption can be calculated exactly by Einstein's equation.An empirical formula which enables one to obtain the same result simply by semilogarithmplot has been suggested.(4)It appears that the effect of pH on absorption is attributed entirely to the dissocia-tion state of sulfanilate.Linear equations have been suggested to describe the interrelation-ship.(5)The effect of humidity on absorption has been discussed.(6)Experiments were designed to determine the minimum inhibiting concentration forrust in leaves,and it was found to be 234—321 micrograms per gram of fresh leaf for Pucciniatriticina four days after inculation.(7)The competitive nature of inhibition of sulfanilic acid was well demonstrated by rever-sing its effect with para-aminobenzoic acid.The affinity of sulfanilic acid to the supposedenzyme in parasite cells was discussed with kinetical approaches.(8)It was found that the toxicity of sulfanilic acid to the host could be relieved by somemineral salts.Discussion was made to explain the possible mechanisms involved.(9)For the distribution of S~(35)-labeled sulfanilic acid in infected leaves,radioautographswere made.The high radioactivity of the infected areas is ascribed mainly to the high affinityof sulfanilic acid to the supposed enzyme in parasite cells.

本文对小麦锈病治疗剂对氨基苯磺酸进行了内吸、运转、分布、抑菌机制、抑菌浓度以及对小麦的毒性等方面的研究和讨论。该药剂的内吸及其在麦叶内的运转,主要是单纯的扩散现象。酸度、温度、湿度和药液浓度对于内吸速度的影响,都可以用数学程式来说明;本文提供了几个经验公式作为参考。从药剂对于病菌体内某些酶的亲和力的考察,以及药剂内吸的自显影图片中放射斑的形状,可以推想病区和菌体,有生物化学性的内吸作用存在。通过对氨基苯甲酸消除药效的试验,提供了一项程式来估计药剂对于寄生菌体内某种酶的相对亲和力。本试验又证明该药剂对于麦苗的毒性可以为矿物质养分所消除。并指出,钙、镁和钾三种元素的解毒途径有各不相同之处。

Polyanemine (zinc salt of 2-mercaptopyrine-N-oxide)exhibited not only the activity against plasmodium berghei in the mice but also the activity against microorganisms in vitro. In order to reaeach a new drug possessing the high activity and little toxi-city,a series of analogs of polyanemine was synthesized and tested for its antimicrobial effect, and one of these, pyrithione sodium (Sodium salt of 2-mercaptopyridine-Na oxide)was found to be the most active compound against the wide range of microorganisms by...

Polyanemine (zinc salt of 2-mercaptopyrine-N-oxide)exhibited not only the activity against plasmodium berghei in the mice but also the activity against microorganisms in vitro. In order to reaeach a new drug possessing the high activity and little toxi-city,a series of analogs of polyanemine was synthesized and tested for its antimicrobial effect, and one of these, pyrithione sodium (Sodium salt of 2-mercaptopyridine-Na oxide)was found to be the most active compound against the wide range of microorganisms by test in vitro and clinical application. In vitro the minimal Inhibiting concentration (MIC) rangs from 0.25μg/ml to 80μg/ml for 17 strains of common fungal pathogens and from 0.63μg/ml to 16μg/ml for 12 strains of common bacterial pathogens. It was synthesiyed by an six-step precedure starting with 2-aminopyridins procured from the local market. The total yield was 37.6%. The mp IR UV spectra of the product were in accord with report mentioned in the foreign literature.

暗罗素不仅是新结构类型的抗疟活性成分,而且具有广谱抗菌作用。为寻找副作用小、疗效高的抗菌新药,作者对暗罗素的结构进行了改造,并合成了一系列类似物。经体外抗菌试验,其中以吡硫霉净的效果最好。本品对费氏志贺氏菌等11种常见细菌的MIC范围为0.63~8μg/ml;对红色癣菌和白念菌等17种常见真菌的MIC范围为0.25~80μg/ml;与益康唑同时对照试验,10种常见真菌中有9种真菌的MIC低于益康唑。本品是以2-氨基吡啶为开饴原料,经六步反应合成的,总收率为37.6%。本品及前体的熔点、光谱分析等均与文献相符。首次制成剂型治疗表浅真菌病320例,总有效率94%。

 
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