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人膀胱癌     
相关语句
  human bladder cancer
     Establishment and Multidrug Resistance Analysis of BIU 87/A, BIU 87/V of Human Bladder Cancer Cell Lines
     人膀胱癌耐药细胞系BIU-87/A、BIU-87/V的建立及耐药分析
短句来源
     Expression of VEGF, TSP-1 and COX-2mRNA in Bladder Transitional Cell Carcinoma and Human Bladder Cancer T24 Cell Line
     膀胱移行细胞癌及人膀胱癌T24细胞中VEGF、TSP-1和COX-2mRNA表达及意义研究
短句来源
     In situ expression of Bcl-2 gene in human bladder cancer cell line BIU-87/ADM
     人膀胱癌BIU-87/ADM细胞中Bcl-2基因的原位表达
短句来源
     Inhibition effect of combining mitomycin C with C_2-ceramide on human bladder cancer T_24 cells
     丝裂霉素C联合C_2-神经酰胺对人膀胱癌T_(24)细胞生长的抑制作用
短句来源
     Analysis of Construction of cDNA Library from Human Bladder Cancer BLZ211 Cells
     人膀胱癌BLZ211细胞cDNA文库的构建分析
短句来源
更多       
  human bladder carcinoma
     The Study on the Effects of nm23-H_1 Gene Transferred into T-24 Cell Lines of Human Bladder Carcinoma
     nm23-H_1基因转染人膀胱癌T-24细胞株的实验研究
短句来源
     Effect and significance of Mitomycin C on Mta-1mRNA and Mta-1pro expression in human bladder carcinoma cell line T24
     丝裂霉素C对人膀胱癌T24细胞Mta-1 mRNA、Mta-1蛋白表达的影响及意义
短句来源
     Effects of 8 Br cAMP on growth related gene expression of human bladder carcinoma BIU 87 cell line
     8-溴环腺苷酸对人膀胱癌BIU-87细胞生长相关基因表达的影响
短句来源
     A study of tumor suppression effect of RB_1 gene on human bladder carcinoma cells in vitro
     RB_1抑癌基因对人膀胱癌细胞抑癌作用的研究
短句来源
     Objective To investigate the influence of over expression of p27 KIP1 on the malignant phenotype of EJ human bladder carcinoma cell line.
     目的 探讨p27KIP1 的过度表达对人膀胱癌细胞系EJ的影响。
短句来源
更多       
  human bladder tumor
     Inhibition of human bladder tumor cell line EJ by adenovirus mediated over expression of human p27 KIP1
     Adp27~(KIP1)基因的过度表达对人膀胱癌细胞系EJ的抑制作用
短句来源
     Human bladder tumor cells(BT5637) were treated with HESW(200sw) alone or in combination with 10hydroxy camptothecinum(01μg/ml).
     采用200SW与0.1μg/ml10-羟基喜树碱单独或联合作用于人膀胱癌细胞(BT5637)。
短句来源
     AIM: To increase the expressed level of a human-mouse chimeric antibody against human bladder tumor in dihydrofo-late reductase (DHFR) defective CHO cells(CHO/DHFR) via weakening the transcription of DHFR gene in the vector.
     目的:提高抗人膀胱癌人-鼠嵌合抗体在二氢叶酸还原酶缺陷的CHO细胞株(CHO/DHFR-)中表达的产量。
短句来源
     A human bladder tumor cell line resistant to adriamycin,BIU-87/ADM,has been established in vitro by the stepwise exposure of BIU-87 human bl adder cancer cell to increasing concentrations of the drug over a period of 8 months.
     为探讨肿瘤细胞耐药性,以人膀胱癌细胞株BIU-87为亲本,以递增阿霉素剂量的方法,历时8个月,成功地诱导建立了一株耐药细胞亚株BIU-87/ADM。
短句来源
     Objective To evaluate the in vitro and in vivo function of anti human bladder tumor human mouse chimeric antibody ch BDI and its future clinical application.
     目的 鉴定抗人膀胱癌人 鼠嵌合抗体ch BDI在荷瘤鼠体内外功能 ,探讨其临床应用价值。
短句来源
更多       
  human bladder
     Establishment and Multidrug Resistance Analysis of BIU 87/A, BIU 87/V of Human Bladder Cancer Cell Lines
     人膀胱癌耐药细胞系BIU-87/A、BIU-87/V的建立及耐药分析
短句来源
     Expression of VEGF, TSP-1 and COX-2mRNA in Bladder Transitional Cell Carcinoma and Human Bladder Cancer T24 Cell Line
     膀胱移行细胞癌及人膀胱癌T24细胞中VEGF、TSP-1和COX-2mRNA表达及意义研究
短句来源
     In situ expression of Bcl-2 gene in human bladder cancer cell line BIU-87/ADM
     人膀胱癌BIU-87/ADM细胞中Bcl-2基因的原位表达
短句来源
     Inhibition effect of combining mitomycin C with C_2-ceramide on human bladder cancer T_24 cells
     丝裂霉素C联合C_2-神经酰胺对人膀胱癌T_(24)细胞生长的抑制作用
短句来源
     The Study on the Effects of nm23-H_1 Gene Transferred into T-24 Cell Lines of Human Bladder Carcinoma
     nm23-H_1基因转染人膀胱癌T-24细胞株的实验研究
短句来源
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  human bladder cancer
Construction and expression of a human-mouse chimeric antibody against human bladder cancer
      
Objective: To construct and express a human-mouse chimeric antibody against human bladder cancer.
      
Method: The variable region genes of anti-human bladder cancer monoclonal antibody BDI-1 were cloned by RT-PCR.
      
Conclusion: The constructed chimeric antibody was expressed successfully in eukaryotic cells, and the chimeric antibody had desired affinity against human bladder cancer cells.
      
The effects of EPI-CDMN associated with external pulsed electromagnetic fields (PEMFs) (10 mT) on killing human bladder cancer BIU-87 cells were studied by MTT assay and Annexin-V/PI double-labeled flow cytometry technique, respectively.
      
更多          
  human bladder carcinoma
TBARS, Carnitine, and Reduced Glutathione Levels in Human Bladder Carcinoma
      
Expression of a mutant hTERT in human bladder carcinoma cell line T24 and its clinical significance
      
Apoptosis induced by ginsenoside Rg3 in a human bladder carcinoma cell line
      
Plasmids encoding each of the mutated SF-1 proteins were cotransfected with the StAR and HDL-R promoter constructs into human bladder carcinoma (HTB-9) cells in the presence or absence of dibutyryl cAMP.
      
Erythroid progenitor cells (BFUe: burst forming units-erythroid) are cultured in 1 ml of 0.35% agarose in IMDM with 30% FBS and conditioned medium from human bladder carcinoma cell line 5637 or recombinant interleukin 3.
      
更多          
  human bladder tumor
An immunoassay using a human bladder tumor tissue culture cell line (J-82) as antigen and a modified avidin-biotin-complex (ABC) method were used to examine human serum samples.
      
Cytotoxic effects of alpha- and gamma-interferon and tumor necrosis factor in human bladder tumor cell lines
      
We investigated the activity of alpha-interferon (α-IFN), gamma-interferon (γ-IFN) and tumor necrosis factor-alpha (TNF-α) in a panel of ten human bladder tumor cell lines.
      
We conclude that α-IFN and TNF are active as single agents and synergistic when used together in vitro in human bladder tumor cell lines.
      
This model more closely resembled the characteristics of human bladder tumor when compared to other bladder cancer models.
      
更多          
  human bladder
TBARS, Carnitine, and Reduced Glutathione Levels in Human Bladder Carcinoma
      
Select cytocompatibility experiments (specifically adhesion and long-term growth studies) were performed on these scaffolds using human bladder smooth muscle cells (BdSMCs).
      
Construction and expression of a human-mouse chimeric antibody against human bladder cancer
      
Objective: To construct and express a human-mouse chimeric antibody against human bladder cancer.
      
Method: The variable region genes of anti-human bladder cancer monoclonal antibody BDI-1 were cloned by RT-PCR.
      
更多          
  其他


Marked hypercalcemia would be caused by ectodermic solid tumor remote from the bone and Without any indication of bone invasion. It suggested that certain humoral factor secreted by the tumor may contribute to the pathogenesis.We partially purified and characterized bone resorption factor (BRF) from human transitional cell carcinoma (TCC) , rat Walker 256 carcinoma and mouse 7,12 dimethyl benz (a) anthracene (DMBA) induced squamous carcinoma. Gel filtration chromatography of tumor extract demonstrates a single...

Marked hypercalcemia would be caused by ectodermic solid tumor remote from the bone and Without any indication of bone invasion. It suggested that certain humoral factor secreted by the tumor may contribute to the pathogenesis.We partially purified and characterized bone resorption factor (BRF) from human transitional cell carcinoma (TCC) , rat Walker 256 carcinoma and mouse 7,12 dimethyl benz (a) anthracene (DMBA) induced squamous carcinoma. Gel filtration chromatography of tumor extract demonstrates a single major peak of bone resorption activity (BRA, 45Ca release from calvarial bone) that elutes with an apparent MW of about 15,000 dalton. The BRA is associated with increased release of immunoreactive PGE 2 and both can be inhibited by indomethacin and boiling. In TCC and DMBA, the BRA were co-eluted with an activity of stimulating aden-ylate cyclase in rat osteosarcoma cells ROS 17/2.8. It appears that these factors are unique BRF, which are different from other known factors that can cause bone resorption.

某些源自外胚层的骨外实体瘤,它们并未浸润至骨组织,但可引起血钙显著增高,提示这些肿瘤可能分泌体液因子作用于骨导致溶骨。我们从人膀胱癌、大鼠乳腺癌(Walker 256)及7.12-Dimethyl Benz[α]anthracene诱发的小鼠鳞癌的提取液中初步分离鉴定了一种溶骨因子。肿瘤提取液经ultrogel层析,发观仅有一溶骨活性峰(~(45)Ca自乳鼠顶骨培养中的释出率),相当于表观分子量15,000道尔顿。此溶骨活性峰与PGE2生成的活性峰相平行,两者均能被Indomethacin及煮沸所抑制。在膀胱癌及鳞癌中,溶骨活性峰还与刺激大鼠成骨肉瘤细胞腺苷酸环化酶的活性相平行。实验结果表明此溶骨因子不同于其它已知能引起溶骨的因子。

A mutant of thermophilic Mastigocladus laminosus, a blue-green algae, has been obtained by mutantion of EMS ( Ethyl Methanesulfonate, Sigma ) and selection of growth on 9T24C tumor cells.Extracts of mutant promote the growth of 9T24C cells in DME/F12 medium supplemented with 0.3% FBS (Fetal Bovine Serum) . The cell number of 9T24C cells increased 3.1-folds in six days when 100 fig/ml extract was added into medium. The molecular weight of unknown active component more than 3500.

本文以EMS(乙基甲烷磺酸盐,Sigma)诱变嗜温的层理鞭枝藻(Mastigocladus laminosus),并经9T24C人膀胱癌细胞生长选择获得突变体。在0.3%FBS(胎牛血清)+DME/F12培养液中加入100μg/ml层理鞭枝藻突变体提取液可促进9T24C癌细胞数在6天中增长3.1倍,而在同样条件下野生型层理鞭枝藻的提取液则对9T24C癌细胞无明显刺激生长作用。这种未知的刺激癌细胞生长的活性物质分子量>3500。

The active ester of chlorambu(?) (CBL) was attached to a monoclonal antibody 5OH·19, against human colorectal cancer cell line (LOVO) to constitute a immunoconjugate CBL-5OH·19. which has a high ratio of CBL per molecule of McAb (25~30: 1) and (?)xcellent targeting activity. The results of (?)0-minute assay and 24-hour assay indicated that CBL-5OH·19 had strong in vitro killing activity to LOVO cells, which was more effective than free CBL. Meanwhile, CBL-5OH·19 was found to have no effect on human bladder tumor...

The active ester of chlorambu(?) (CBL) was attached to a monoclonal antibody 5OH·19, against human colorectal cancer cell line (LOVO) to constitute a immunoconjugate CBL-5OH·19. which has a high ratio of CBL per molecule of McAb (25~30: 1) and (?)xcellent targeting activity. The results of (?)0-minute assay and 24-hour assay indicated that CBL-5OH·19 had strong in vitro killing activity to LOVO cells, which was more effective than free CBL. Meanwhile, CBL-5OH·19 was found to have no effect on human bladder tumor cell line (E-J) and the conjugate CBLOIgG had no killing effect on both of LOVO and E-J cells. These results indicated that CBL-5OH·19was not only effective but also specific in killing the human colorectal cancer cells.

苯丁酸氮芥(CBL)的活性酯通过共价联接的方式与抗人直肠癌单克隆抗体5OH.19偶联,形成的免疫偶联物CBL一5OH.19具有较高的药物/抗体比率(25~30∶1)以及很好的导向活性。在体外30分钟试验和24小时试验中,CBL—50H.19对人直肠癌LoVo细胞均具有很强的体外杀伤活性.其效果比游离的CBL强。CBL—50H.19对人膀胱癌E—J细胞无杀伤活性;CBL与正常小鼠IgG偶联组成的免疫偶联物对LoVo细胞和E—J细胞均无杀伤作用。这表明CBL—50H.19对人直肠癌细胞不但具有较强的杀伤能力.而且具有好的杀伤特异性.

 
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