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icr种小鼠
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  icr mice
     Methods 40 ICR mice were divided into four groups: the control,the low(0.5 mg /kg),the middle(4 mg/kg) and the high(20 mg/kg),intragastric through mouth for 21 d,detected the thymocyte apoptosis by flow cytometry,observed the fas protein expression in thymus by immunohistochemistry.
     方法ICR种小鼠体重20~25 g,雄、雌各半,共40只,随机分为4组,每组10只,即1个对照组和低、中和高3个组,经口灌胃21 d,流式细胞仪检测胸腺细胞凋亡状况,免疫组化染色,观察Fas蛋白在胸腺的表达。
短句来源
     In ICR mice, TW19 inhabited splenic T and B cells proliferation in vitro and suppressed antibody formation in vivo .
     TW1 9对体外培养的 T、B淋巴细胞具有抑制作用 ,而抑制 ICR种小鼠体内抗体的生成 ,但是对于整体动物 B细胞的增殖和补体 C3的产生有促进作用
短句来源
     Five weeks after TW19 treatment at anti fertility dose, number and motility of spermatozoa and testis weights reduced significantly in SD rats and Kunming mice, but no effects were observed in ICR mice.
     TW1 9在抗生育有效剂量时能使昆明种小鼠及 SD大鼠附睾内精子数量和活动力下降 ,睾丸重量减轻 ,而对 ICR种小鼠没有影响。
短句来源
     PARTICIPANTS:The experiment was completed in the Department of Bioengineering,School of Life Science and Technology in Xi'an Jiaotong University from March to May 2003.ICR mice of clean grade, weighing 20 g to 40 g,were provided by the Shaanxi Academy of Traditional Chinese Medicine[Certification No.08-004].
     材料:实验于2003-03/05在西安交通大学生命科学与技术学院生物工程系完成,选择清洁级ICR种小鼠,体质量20~24g. 陕西省中医药研究院提供犤陕医动(字)08-004犦。
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  “icr种小鼠”译为未确定词的双语例句
     Results of acute toxicity test showed that the breakdown products of silk fibroin belonged to nontoxicity products, as LD50 on both male and female of ICR and SD mice were above 10 g/kg body weight.
     家蚕丝素分解物的急性毒性检测,雌雄ICR种小鼠和SD种大鼠的经口LD50均大于10g/kg体重,属实际无毒。
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  相似匹配句对
     Then,the purified recombinant protein was immunized to ICR mice in order to induce immune responses which could be detected by Western blotting and ELISA.
     免疫ICR小鼠,获得抗血清。
短句来源
     The experimental animals were mice of Kunming strain.
     实验动物为昆明小鼠
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     The experimental animals were mice of Kunming strain.
     实验动物为昆明小鼠
短句来源
     Determination of Trace Elements in ICR Mice Functional Viscera
     ICR小鼠功能脏器微量元素的测定
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     than that in WT mice.
     通小鼠
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  icr mice
Twenty-five tiptoe-walking Yoshimura (twy) mice with calcified mass lesions compressing the spinal cord posterolaterally at the C1-C2 vertebral levels were compared with five Institute of Cancer Research (ICR) mice that served as controls.
      
albicans) in mice, the fungal vaginitis model was established in female ICR mice by intravaginal inoculation of suspension of C.
      
To study the effect of itraconazole on the vaginal candidiasis caused by Candida under different immunity conditions, the fungal vaginitis model was established in female ICR mice by intravaginal inoculation of suspension of C.
      
The relationship between Ni-induced hepatic lipid peroxidation (LPO) and the concentrations of Ni and trace elements was investigated in male ICR mice.
      
The l-SeMet α,γ-elimination enzyme was ubiquitous in tissues from ICR mice and the activity was relatively high in the large intestine, brain, and muscle, as well as the liver.
      
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TW19 is a diterpene compound isolated from root derma of Tripterygium Wilfordii Hook.F .. Its effects on immune function in ICR mice and male fertility in SD rat, ICR mice and Kunming mice were evaluated. TW19 was administrated by oral garage for 5 weeks. The anti fertility efficacy was assessed with mating tests. The results showed that ED 50 of anti fertility is 332.0 μg/kg/day, 369.9 μg/kg/day and 286.8 μg/kg/day respectively in SD rats, ICR mice and Kunming mice. Five weeks after TW19 treatment...

TW19 is a diterpene compound isolated from root derma of Tripterygium Wilfordii Hook.F .. Its effects on immune function in ICR mice and male fertility in SD rat, ICR mice and Kunming mice were evaluated. TW19 was administrated by oral garage for 5 weeks. The anti fertility efficacy was assessed with mating tests. The results showed that ED 50 of anti fertility is 332.0 μg/kg/day, 369.9 μg/kg/day and 286.8 μg/kg/day respectively in SD rats, ICR mice and Kunming mice. Five weeks after TW19 treatment at anti fertility dose, number and motility of spermatozoa and testis weights reduced significantly in SD rats and Kunming mice, but no effects were observed in ICR mice. In ICR mice, TW19 inhabited splenic T and B cells proliferation in vitro and suppressed antibody formation in vivo .

TW1 9系从雷公藤根皮中提取分离出的一个二萜类化合物 ,本文比较了 TW1 9对SD大鼠、ICR小鼠和昆明种小鼠的雄性抗生育作用 ,以及对 ICR小鼠免疫功能的影响。TW1 9连续 5周灌服给药 ,以交配试验观察抗生育效果。结果显示 TW1 9对 SD大鼠、ICR小鼠、昆明种小鼠抗生育作用的半数有效剂量 (ED50 )分别为 332 .0μg/kg、36 9.9μg/kg、2 86 .8μg/kg。TW1 9在抗生育有效剂量时能使昆明种小鼠及 SD大鼠附睾内精子数量和活动力下降 ,睾丸重量减轻 ,而对 ICR种小鼠没有影响。TW1 9对体外培养的 T、B淋巴细胞具有抑制作用 ,而抑制 ICR种小鼠体内抗体的生成 ,但是对于整体动物 B细胞的增殖和补体 C3的产生有促进作用

Pathological, biochemical tests have been carried out on mice after fed with silk fibroin protein. The results showed that breakdown products of silk fibroin protein obviously had supplementary protective effects on liver chemical injury. Results of acute toxicity test showed that the breakdown products of silk fibroin belonged to nontoxicity products, as LD50 on both male and female of ICR and SD mice were above 10 g/kg body weight. Ames test turned out to be negative. Silk breakdown products had no obvious...

Pathological, biochemical tests have been carried out on mice after fed with silk fibroin protein. The results showed that breakdown products of silk fibroin protein obviously had supplementary protective effects on liver chemical injury. Results of acute toxicity test showed that the breakdown products of silk fibroin belonged to nontoxicity products, as LD50 on both male and female of ICR and SD mice were above 10 g/kg body weight. Ames test turned out to be negative. Silk breakdown products had no obvious effects on micronucleus of bone marrow polydye erythrocyte and sperm deformity.

通过对昆明种小白鼠的生化检测和病理检查表明,家蚕丝素分解物对化学性肝损伤具有明显的辅助保护作用。家蚕丝素分解物的急性毒性检测,雌雄ICR种小鼠和SD种大鼠的经口LD50均大于10g/kg体重,属实际无毒。Ames回变菌落试验呈阴性。在试验浓度范围内,家蚕丝素分解物对小鼠骨髓嗜多染红细胞微核率及精子畸形发生率均未有明显影响。

BACKGROUND:Fructus Zipiphi Jujubae,with certain cyclic adenosine monophosphate(cAMP) and cyclic guanosine monophosphate(cGMP),has effects on hypertension,diabetes,cancer and cardiogenic shock.But there has been rare report on the influence of Fructus Zipiphi Jujubae on blood lipid. OBJECTIVE:To study the effects of juice of Fructus Zipiphi Jujubae on body function and blood lipid level in mice. DESIGN:A completely randomized basic study taking experimental animals as the subjects. SETTINGS:Department of...

BACKGROUND:Fructus Zipiphi Jujubae,with certain cyclic adenosine monophosphate(cAMP) and cyclic guanosine monophosphate(cGMP),has effects on hypertension,diabetes,cancer and cardiogenic shock.But there has been rare report on the influence of Fructus Zipiphi Jujubae on blood lipid. OBJECTIVE:To study the effects of juice of Fructus Zipiphi Jujubae on body function and blood lipid level in mice. DESIGN:A completely randomized basic study taking experimental animals as the subjects. SETTINGS:Department of bioengineering,school of life science and technology in a university;Department of endocrinology in a university hospital. PARTICIPANTS:The experiment was completed in the Department of Bioengineering,School of Life Science and Technology in Xi'an Jiaotong University from March to May 2003.ICR mice of clean grade, weighing 20 g to 40 g,were provided by the Shaanxi Academy of Traditional Chinese Medicine[Certification No.08-004]. Juice of Fructus Zipiphi Jujubae:The Chinese date was picked, cleaned,heated and fractured moderately,mixed with water of 10 times and pectinase with the quantity percentage of 0.70%,soaked at 50 ℃for 6 hours,then the juice was filtered and condensed into 16%soluble solids,then sterilized for use later.Forty-eight mice (24 male and 24 female) were randomly divided into 4 groups according to body mass with 12 in each group:normal control group(group A), normal date juice group(group B),model control group(group C) and model date juice group(group D). INTERVENTIONS:Mice in group A were fed with basic diet,drank water for 24 hours;Mice in group B were fed with basic diet,drank water and date juice for 12 hours respectively;Mice in group C were fed with high-fat diet,drank water for 24 hours;Mice in group D were fed with high-fat diet,drank water and date juice for 12 hours respectively.Changes of body mass,indexes of thymus gland and spleen were measured after treated with date juice for 30 days.High fat mice models were established,and blood lipid indexes were determined. MAIN OUTCOME MEASURES:Food efficiency of mice,index of thymus gland,spleen index,growth index of mice. RESULTS:The food efficiency and the indexes of thymus gland and spleen in group B were(9.93±0.473) g/100 g,3.27±0.35 and 2.93±0.51 respectively,which were all obviously higher than those in group A[(7.56±0.382) g/100 g,(3.14±0.54),(2.87±0.33)](t=2.55,2.37,2.41,P< 0.05).The body mass was obviously higher in group B [(36.73 ±4.70) g] than in group A[(34.92 ±5.12) g] (t=2.32,P< 0.05);while those were very significantly higher in group C and group D [(39.83 ±6.00), (37.63 ±2.73) g] than in group A and group B[(34.92 ±5.12), (36.73 ±4.70) g](t=4.13,2.48,P< 0.01),and that in the group D[(37.63 ±2.73) g] was obviously lighter than that in the group C[(39.83 ±6.00)g](t=2.26,P< 0.05).The serum levels of total cholesterol(TC) in the in group C and group D were significantly higher than those in group A and group B(P< 0.01), while that was significantly lower in group D than in group C(P< 0.05). The serum levels of triglyceride(TG),low-density lipoprotein-cholesterol(LDL-C),arteriosclerosis index(AI),high-density lipoprotein-cholesterol(HDL-C) and HDL-C/TC were significantly higher in group C than in group A(P< 0.01,P< 0.05).TC, HDL-C,AI,HDL-C/TC,TG and LDL-C in group D were lower than those in group C(P< 0.05,P< 0.01). CONCLUSION:Juice of Fructus Zipiphi Jujubae can obviously increase the body mass,promoting food efficiency and indexes of thymus gland and spleen of mice, and has the significant effect on the reinforcement of body function in mice.Juice of Fructus Zipiphi Jujubae can decrease the serum levels of TC,TG and LDL-C in mice with hyperlipidemia,and has the remarkable ameliorating effect on hyperlipidemia of mice induced by high-fat feed.

背景:红枣中含一定量的环磷酸腺苷和环磷酸鸟苷,对高血压、糖尿病、癌症、心源性休克等有一定疗效。而红枣对血脂影响的报道结果较少。目的:探讨红枣汁对小鼠身体机能和血脂水平的影响。设计:以实验动物为研究对象,完全随机分组设计。单位:一所大学的生命科学与技术学院生物工程系,一所大学医院的内分泌科。材料:实验于2003-03/05在西安交通大学生命科学与技术学院生物工程系完成,选择清洁级ICR种小鼠,体质量20~24g.陕西省中医药研究院提供犤陕医动(字)08-004犦。红枣汁:陕北木枣,经挑选、洗涤、热处理、适度破碎,加入10倍水、质量分数为0.70%果胶酶,于50℃下恒温浸泡6h,过滤,滤液浓缩至可溶性固形物含量为16%,杀菌备用。取48只小鼠,雌雄各24只,按体质量随机分4组,各12只,包括正常对照组,正常给枣汁组,模型对照组,模型给枣汁组。方法:正常对照组饲以基础饲料、24h给水;正常给枣汁组饲以基础饲料、12h给水、12h给枣汁;模型对照组饲以高脂饲料、24h给水;模型给枣汁组饲以高脂饲料、12h给水、12h给枣汁。测定红枣汁喂养30d后小鼠的体质量变化、胸腺、脾脏指数,用高脂饲料造成小鼠高脂模型...

背景:红枣中含一定量的环磷酸腺苷和环磷酸鸟苷,对高血压、糖尿病、癌症、心源性休克等有一定疗效。而红枣对血脂影响的报道结果较少。目的:探讨红枣汁对小鼠身体机能和血脂水平的影响。设计:以实验动物为研究对象,完全随机分组设计。单位:一所大学的生命科学与技术学院生物工程系,一所大学医院的内分泌科。材料:实验于2003-03/05在西安交通大学生命科学与技术学院生物工程系完成,选择清洁级ICR种小鼠,体质量20~24g.陕西省中医药研究院提供犤陕医动(字)08-004犦。红枣汁:陕北木枣,经挑选、洗涤、热处理、适度破碎,加入10倍水、质量分数为0.70%果胶酶,于50℃下恒温浸泡6h,过滤,滤液浓缩至可溶性固形物含量为16%,杀菌备用。取48只小鼠,雌雄各24只,按体质量随机分4组,各12只,包括正常对照组,正常给枣汁组,模型对照组,模型给枣汁组。方法:正常对照组饲以基础饲料、24h给水;正常给枣汁组饲以基础饲料、12h给水、12h给枣汁;模型对照组饲以高脂饲料、24h给水;模型给枣汁组饲以高脂饲料、12h给水、12h给枣汁。测定红枣汁喂养30d后小鼠的体质量变化、胸腺、脾脏指数,用高脂饲料造成小鼠高脂模型,测定血脂指标。主要观察指标:小鼠食物功效、胸腺指数、脾指数,小鼠生长指标。结果:给枣汁组食物功效、胸腺指数、脾?

 
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