Methods The expression of P glycoprotein in specimens of 80 cases of urinary bladder transitional cell carcinoma and 20 normal bladder samples were detected with stroptavidin biotin peroxidase complex (S ABC) methods.
It was concluded that loss of expression of ECD is an useful parameter of malignancy of the carcinoma and detection of ECD expression might have a practical significance in assessing the malignancy,recurrence and prognosis of urinary transitional cell carcinoma.
Using colony formation technique and KK-47 cell line established from a human bladder transitional cell carcinoma, the effects of 6 anticancer drugs, thio-TEPA, Bleomycin, mitomycin C, carbazilquinone, Adriamycin and cis-Platinum, were compared.
Monoclonal antibodies produced against tumor associated antigens of human bladder transitional cell carcinoma have proved to be useful in detecting malignant cells in tumor sections and bladder washings.
Transferrin receptor expression by human bladder transitional cell carcinomas
Expression of the ras and the c-erbB-2 oncogene products was investigated in 56 cases of human bladder transitional cell carcinoma and 6 samples of human normal bladder tissue using an immunohisto-chemical method.
In the present study it was aimed to investigate the frequency of K-RAS mutation in the human bladder transitional cell carcinoma.