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溃疡
相关语句
  ulcer
    THE PROTECTIVE EFFECTS OF FURAZOLIDONE AND SOME COMMONLY USED ANTIULCER DRUGS ON SEVERAL GASTRIC ULCER MODELS IN RATS
    呋喃唑酮和一些常用抗溃疡药对四种大鼠胃溃疡模型的影响
短句来源
    SYNTHESIS OF PIRENZEPINE——A DRUG FOR PEPTIC ULCER
    抗消化性溃疡药哌吡(艹卓)酮的合成
短句来源
    Is Campylobacter Pyloridis(CP)a Cause of Peptic Ulcer(PU)? A Controlled Clinical Research of 58 Cases
    幽门弯曲菌(CP)与消化性溃疡(PU)的关系——附58例临床研究
短句来源
    Omeprazole in treating hemorrhage from peptic ulcer and chronic gastritis in 103 patients
    奥美拉唑治疗消化性溃疡及慢性胃炎引起的出血103例
短句来源
    Clinical Observation of the Treatment of Peptic Ulcer with Famotidine──42 cases
    法莫替丁治疗消化性溃疡42例临床观察
短句来源
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  ulceration
    Recombinant Human Granulocyte Colony Stimulating Factor for Drug Induced Skin Ulceration
    重组人粒细胞集落刺激因子促进药物性溃疡愈合的实验研究
短句来源
    The result showed that ulcerlmin with 25%glucose-solution had a significant preventive effect onstress ulceration in rats,whereas 25% glucose solutionwith energy mixture and fat emulsion had nopteventive effect.
    结果表明:硫糖铝、1.39mmol/L葡萄糖液对大鼠应激性溃疡具有显著预防作用,而1.39mmol/L葡萄糖液加能量合剂和脂肪乳剂均无预防作用。
短句来源
    The obvious irritation hadn't be seen in low and middle dose, but inflammation, congestion, hemorrhage and ulceration could be found in vaginal mucous membrane in high dose in vaginal irritation test.
    在阴道刺激试验中低剂量未引起阴道明显的刺激反应,高剂量可引起阴道粘膜炎细胞浸润、淤血、出血及溃疡等病理变化。
短句来源
  gastric ulcer
    THE PROTECTIVE EFFECTS OF FURAZOLIDONE AND SOME COMMONLY USED ANTIULCER DRUGS ON SEVERAL GASTRIC ULCER MODELS IN RATS
    呋喃唑酮和一些常用抗溃疡药对四种大鼠胃溃疡模型的影响
短句来源
    The study on the effect of Aluminum Alginate anti gastric ulcer
    海藻酸铝抗溃疡作用的研究
短句来源
    Thestudy on the mechanism of facilitation of gastric ulcer healing by omeprazole
    洛赛克促进溃疡愈合机制的研究
短句来源
    Effect of Weichangle on Expression of HSP_(70) and HSP_(27) and Healing Quality in Rats with Chronic Acetous Gastric Ulcer
    胃肠乐对乙酸慢性胃溃疡大鼠HSP_(70)、HSP_(27)表达及溃疡愈合质量的影响
短句来源
    Oral administration of 100,200mg/kg×10 caused a potentinhibition of the acetic acid induced chronic gastric ulcer in rats. Its effectsagainst peptic ulcer were comparable to FM100(Aspalon).
    甘酮酸100或200mg/kg po 10次,能抑制醋酸诱发的大鼠慢性溃疡,其抗溃疡作用与日本已上市的 FM100(Aspalon)相似。
短句来源
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  “溃疡”译为未确定词的双语例句
    Synthesis of “Kui Xiao Jing” (Trithiozine)-A New Antiulcer Drug
    新型抗溃疡药溃消净(Trithiozine)的合成
短句来源
    STUDIES ON THE ANTI-ULCER ACTION OF FOUR POLYSACCHARIDES
    四种多糖抗溃疡作用的研究
短句来源
    The effect of histamine H_2 receptor blocker famotidine on the gastric function and ulcer-index in rats of hemorrhagic stress
    组胺H_2受体阻断剂对大鼠失血性应激反应时胃功能和溃疡指数的影响
短句来源
    PHARMACOLOGICAL STUDY OF ANTI-ULCER AGENT PROGLUMIDE
    抗溃疡药丙谷胺的药理研究
短句来源
    Carnosine Zine Complex
    抗溃疡药——肌肽锌(Z-103)
短句来源
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  ulcer
Diclofenac (25 mg kg-1) and meloxicam (7.5 mg kg-1) produced 9.3 and 19.6 mm2 ulcer areas in stomachs of rats, respectively, when used alone, but when combined with nimesulide diclofenac and meloxicam did not cause any injury in rat stomachs.
      
While ranitidine at 100 mg kg-1 dose prevented diclofenac-induced ulcer formation, it reduced meloxicam-induced ulcer formation significantly.
      
Antiulcer Effects of the Tripeptide PGP and Its Possible Metabolites (PG, GP, Glycine, and Proline) in Different Models of Ulcer
      
PG reduced the ethanol- and indomethacin-induced lesions approximately twofold but was considerably less effective in stress-induced ulcer.
      
GP decreased the stress- and indometacin-induced ulcer but tended to stimulate the ethanol-induced lesions.
      
更多          
  ulceration
We propose to treat deep corneal burns by grafting a living stromal equivalent, since keratocyte death and stromal destruction are the main factors of ulceration and destruction of the eye.
      
The Pro-Gly-Pro glyproline increases a resistance of the gastric mucosa (GM) to ulcerogenic factors in various models of ulceration and exhibits therapeutic properties in acceleration of the healing of an acetate ulcer.
      
Statistically reliable antiulcer effects in all the ulceration models were found for only two peptides: PGP and GPGPGP.
      
The PGP tripeptide displays a wide spectrum of physiological activities and affects a number of mechanisms that cause the development of GM ulceration.
      
The damage of barrier in mucosa with erosion or ulceration, and the thickness of mucin were examined by scanned electron microscope (SEM).
      
更多          
  gastric ulcer
About 30% of patients with gastritis, active duodenal or gastric ulcer had antibody levels as low as the seroconverted dyspeptic patients but with normal gastroduodenal mucosa.C.
      
Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer
      
Effect of mexican tea herb and pilular adina herb on concrescence of gastric mucosa in experimental gastric ulcer rats
      
pylori-infected child, and current guidelines recommend eradication therapy for infected children with duodenal and gastric ulcer, gastric lymphoma, and atrophic gastritis with intestinal metaplasia.
      
Other "less traditional" therapies, including probiotics, heparins, and anti-gastric ulcer remedies, challenge our understanding of the pathogenesis of ulcerative colitis and may provide further insights into future therapies.
      
更多          


"Kui Xiao Jing",4-(3,4,5-Trimethoxythiobenzoyl)-tetrahydro-1,4-oxazine (commercial name Trithiozine), has been synthesized in our laboratory. The total yield is 57% from Gallic Acid. In this process, the two final products have been identified by elemental analysis and spectrum. Antisecretory and antiulcer effects of "Kui Xiao Jing" can be compared with those of "Cimetidine".

“溃消净”,4-(3,4,5-三甲氧基硫代苯甲酰基)-四氢-1,4-氧嗪(商品名Trithiozine),在我们实验室试制成功。以没食子酸为原料,总收率达到57%。我们对此路线中的后面两个化合物进行了元素分析及光谱鉴定。“溃消净”的抑制胃酸分泌及抗溃疡作用可与甲氰咪胍(Cimetidine)相匹敌。

Furazolidone in relatively small doses(i. e., 20~50 mg/kg) was found to be an effective anti-ulcer agent in three experimental gastric ulcer models in rats, namely, the acetic acid-induced chronic ulcer, indomethacin-induced and pyloric ligation induced ulcers. Among these, the indomethacin-induced ulcer was particularly markedly inhibited. In addition, a decrease of pepsin activity, an increase of hexosamine level and, in larger doses, a decrease of volume of gastric juice collected from pyloric-ligated stomaches...

Furazolidone in relatively small doses(i. e., 20~50 mg/kg) was found to be an effective anti-ulcer agent in three experimental gastric ulcer models in rats, namely, the acetic acid-induced chronic ulcer, indomethacin-induced and pyloric ligation induced ulcers. Among these, the indomethacin-induced ulcer was particularly markedly inhibited. In addition, a decrease of pepsin activity, an increase of hexosamine level and, in larger doses, a decrease of volume of gastric juice collected from pyloric-ligated stomaches were also observed. However, the drug was shown to be ineffective against the stress-restraint ulcer model.The above characteristic pattern of furazolidone action on various animal ulcer models was found not to be shared by known anti-ulcer drugs such as carbenoxolone, atropine, cimetidine and doxepin. Furazolidone and carbenoxolone showed synergistic effects on the pyloric ligation model. Therefore, it would be advisable to use a combination of subtherapeutic doses of both drugs in clinical gastric ulcer therapy, in expectation of obtaining better efficacy and fewer adverse effects.

呋喃唑酮在较小剂量(20~50mg/kg)即能对三种大鼠胃溃疡模型(慢性醋酸型,消炎痛型,幽门结扎型)显示明显的保护作用,对消炎痛模型的保护作用尤为突出。本药对应激型溃疡模型无效。已知的治疗消化性溃疡药物—生胃酮,阿托品、甲氰脒胍及多虑平并不显示上述作用特色。呋喃唑酮和生胃酮对幽门结扎模型的保护有协同作用。此外还对胃液进行了生化分析。

Cysteamine can deplete tissue somatostatin (SRIF) and induce duodenal ulcers in rats. It was observed that bovine pancreatic polypeptide (BPP) inhibited cysteamine-induced duodenal ulcers, and prevented cysteamine-induced SRIF depletion in duodenal mucosa in rats. It suggests that BPP may protect duodenal mucosa from ulceration by preventing local SRIF depletion caused by cysteamine.

半胱胺可以引起大鼠体内生长抑素耗竭并诱发十二指肠溃疡。本工作发现,腹腔注射牛胰多肽可以减轻半胱胺引起的大鼠十二指肠溃疡,还可防止半胱胺引起的大鼠十二指肠粘膜生长抑素含量的下降。这项工作提示,牛胰多肽可能通过防止局部生长抑素的耗竭对十二指肠起到保护作用。

 
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