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门脉     
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  portal
    The Study on the Regulatory Mechanism of ET-1、NO、PGL_2 and C-Type Natriuretic Peptide on Hyperdynamic Circulation in Hepatic Cirrhosis and Portal Hypertension
    ET-1、NO、PGL_2、C型利钠肽对肝硬化门脉高压高动力循环调控机制的研究
短句来源
    Effects of ET-1 on Portal Hypertension in Hepatic Cirrhosis and the Mechanism of CNP、Radix Salviae Miltiorrhizae on ET-1-Mediated Contraction of HSCs
    ET—1对肝硬化门脉高压的作用及CNP、丹参对ET—1介导肝星状细胞收缩的调控机制
短句来源
    Prognosis of Portal Cirrhosis (Long Term Follow-up of 245 cases)
    245例门脉性肝硬化的预后(长期随访观察)
短句来源
    An Experimental Study of the Relationship between Hepatic Fibrosis and Portal Hypertension
    肝纤维化与门脉高压关系的实验研究
短句来源
    Relationship between splanchnic plasma thromboxane A_2/prostacyclin levels and portal hemodynamics in cirrhotic dogs
    胆管结扎肝硬化犬血浆TXA_2/PGI_2变化及其与门脉血液动力学的关系
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  portal vein
    Methods Internal diameter (mm), cross section area (cm2) and blood flow velocity (cm/s) of the portal vein were detected by color Doppler separately in 10 cases(control group), 27 cases with compensated liver cirrhosis(compensated group) and 13 cases decompensated liver cirrhosis (decompensated group).
    ②方法用彩色多普勒超声对正常对照组(10例),代偿期肝硬化组(27例)和失代偿期肝硬化组(13例)患者门静脉内径、门静脉横截面积和血流速度分别进行检测。 ③结果代偿期肝硬化组、失代偿期肝硬化组组间的门静脉主干内径、门脉截面积、门脉充血指数是逐渐增加的,与对照组比较有显著性差异;
短句来源
    Results The internal diameter, cross section area and congestive index of liver portal vein increased, blood flow velocity and blood flow volume of liver portal vein decreased gradually from control group, compensated group to decompensated group , and there was significant difference among groups;
    对照组、代偿期肝硬化组、失代偿期肝硬化组组间的门脉血流速度是逐渐减少的,与对照组比较有显著性差异; 对照组、失代偿期肝硬化组组间以及代偿期肝硬化组、失代偿期肝硬化组组间的门脉血流量是下降的,与对照组比较有显著性差异;
短句来源
    [Conclusion ]TIPS can lower portal vein pressure and reduce concentration of ET,PRA and ATⅡin patients with liver cirrhosis.
    术后腹水较术前明显减少。 [结论]TIPS能有效降低门脉压,降低血浆ET、PRA及ATⅡ的浓度,改善患者门脉系统及全身的血循环。
短句来源
    Compared to that control group and before treatment,portal vein blood flow improves significantly in trial group (P< 0.05).
    6、治疗组能显著改善患者的门脉血流量,与对照组及治疗前比较均有显著性差异(P<0.05)。
    Clinical Observation on Pituitrin and Nitroglycerin in Treatment of Haemorrhage Resulting from High Pressure of Portal Vein Related to Hepatocirrhosis
    垂体后叶素并硝酸甘油治疗肝硬化门脉高压出血临床观察
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  portal venous
    Effect of Domperidone on the Blood Flow of Portal Venous System in Patients with Liver Cirrhosis
    多潘立酮对肝硬化患者门脉系统血流量的影响
短句来源
    Effect of H2-receptor blocker combined with domperidone on the blood flow of portal venous system in patients with liver cirrhosis
    H2受体阻滞剂联合多潘立酮对肝硬化患者门脉血流的影响
短句来源
    Results: It was found that the PVP and the concentration of CGA in peripheral venous blood increased markedly, the concetration of CGA in portal venous blood decreased in early stage of liver cirrhosis.
    结果:肝硬化早期PVP增高,外周血CGA增高,门脉血CGA降低。
短句来源
    The level of SAAG had no correlation with the level of portal venous pressure(r=-0.140,P=0.649).
    SAAG与门脉压力升高的程度无关(r=-0.140,P=0.649)。
短句来源
    Results: Cirrhosis complicated hemorrhage of upper digestive tract had prominently interralations with the factors of esophageal varicosis(OR=3.942,P=0.001),liver function grade(OR=1.028,P=0.003),portal venous high pressure stomach trouble(OR=3.862,P=0.002).
    结果:肝硬化并发上消化道出血与食道静脉曲张(OR=3.942,P=0.001),肝功能分级(OR=1.028,P=0.003),门脉高压性胃病(OR=3.862,P=0.002)有显著相关性。
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  patients with portal
    Methods Reverse transcription and polymerse chain reaction (RT-PCR)was used to detect the expression of gax mRNA and immunohistochemistry straining was per- formed to examine the expression of PCNA protein in splenic vein of 28 patients with portal hypertension (experimental group)and 12 normal vasculatures(control group).
    方法应用逆转录-聚合酶链反应(RT-PCR)和免疫组织化学法分别检测28例门脉高压症患者脾静脉和12例正常对照血管gax mRNA和PCNA蛋白的表达。
短句来源
    Clinical evaluation of ~(99)Tc~m-MIBI per-rectal portal scintigraphy in differential diagnosis and efficacy of drug therapy for patients with portal hypertension of hepatocirrhosis
    ~(99)Tc~m-MIBI经直肠-门脉闪烁显像对肝硬化伴门脉高压患者的鉴别诊断和疗效评估
短句来源
    Clinic analysis of the relationship between hemorrhage of upper digestive tract in 230 cirrhotic patients with portal hypertensive gastropathy
    230例肝硬化患者上消化道出血与门脉高压性胃病关系临床分析
短句来源
    Effect of hyperbaric oxygen therapy on hemodynamics of cirrhotic patients with portal hypertension
    高压氧治疗对肝硬化门脉高压症患者血流动力学的影响
短句来源
    CLINICAL ANALYSIS OF RELATIVE FACTORS IN PATIENTS WITH PORTAL HYPERTENSIVE GASTROPATHY
    门脉高压性胃病相关因素临床分析
短句来源
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      portal
    We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.
          
    Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension (26 years clinical obse
          
    The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated.
          
    In this study, we evaluated the effectiveness of a new treatment strategy: splenic auto-transplantation and oesophageal transection anastomosis on 274 patients from three aspects: clinical observation, splenic immunology and portal dynamics.
          
    From 1979 to 2005, 274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes, which were then compared with those of the traditional surgery treatment.
          
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      portal vein
    Trifurcation of the portal vein was seen in nine cases.
          
    Majority of the hepatic flow from the portal vein can be maintained adequately.
          
    Overall hypohydration of the body prevented the dilation of hepatic veins typical of an AOP while not affecting noticeably the venous congestion in the portal vein system.
          
    Dogs were instrumented with indwelling portal vein and carotid artery catheters, a catheter jejunostomy and an electromagnetic flow measuring probe around the portal vein enabling continuous flow recordings.
          
    Methods Sub-adult pigs were fitted, under anaesthesia, with permanent catheters in the portal vein, carotid artery and urethra, and with an electromagnetic flow probe around the portal vein.
          
    更多          
      portal venous
    Development of a chronic canine model for measurement of absorption by substrate appearance in portal venous blood
          
    Following intrajejunal infusion of nutritive substrates in the conscious animal, absorption was measured as the product of porto-arterial substrate difference and portal venous flow.
          
    (3) Infusion of complete nutritive formulas caused a significant increase in portal venous flow whereas neither saline nor the amino acids or the peptides investigated had a comparable effect.
          
    In summary, this method permits for the first time quantitative measurement of absorption by appearance rates in portal venous blood instead of by disappearance from the intestinal lumen.
          
    Portal venous gas (PVG) is a rare condition that can occur after blunt abdominal trauma.
          
    更多          
      patients with portal
    Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension (26 years clinical obse
          
    From 1979 to 2005, 274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes, which were then compared with those of the traditional surgery treatment.
          
    Forty-three patients with portal hypertension were treated by small-diameter H-graft of ePTFE portacaval shunt from May 1995 to April 2006.
          
    Portal hypertensive gastropathy (PHG) causes both acute and chronic blood loss from the gastrointestinal tract in patients with portal hypertension.
          
    Treatment of gastropathy and gastric antral vascular ectasia in patients with portal hypertension
          
    更多          


    The prognosis of portal cirrhosis of the liver is closely related to clinical features and many other factors. In this paper, we analyzed the long-term follow-up observation on 245 cases with portal cirrhosis of the liver hospitalized in Tianjin Medical College Hospital from 1947 to 1959, in order to find out the relationship between the prognosis and certain clinical features.In this series, 54.28 months was the average clinical course from beginning of the 1st symptom to the time at which the patient died...

    The prognosis of portal cirrhosis of the liver is closely related to clinical features and many other factors. In this paper, we analyzed the long-term follow-up observation on 245 cases with portal cirrhosis of the liver hospitalized in Tianjin Medical College Hospital from 1947 to 1959, in order to find out the relationship between the prognosis and certain clinical features.In this series, 54.28 months was the average clinical course from beginning of the 1st symptom to the time at which the patient died or at which the last followup was performed. The mortality rate was highest, around 50%, within the 1st year after appearance of the 1st symptom, afterwards the mortality rate was markedly decreased and become stationary to some extent.Of 190 cases with ascites, 31 months was the average duration from appearance of ascites to the time at which the patient died or at which the last follow-up was performed. The longest survival term after appearance of ascites was 31 years. The highest mortality rate occurred in the 1st year after the appearance of ascites and was more than fifty percents. Afterwards, the mortality rate was markedly decreased.In 130 cases with massive gastrointestinal hemorrhage, 34.39 months was the average duration from the onset of hemorrhage to the time at which the patient died or at which the last follow-up was performed. The highest mortality rate occurred within the 1st eight weeks after the onset of hemorrhage and was more than fifty percent. Afterwards the mortality rate was markedly decreased.In 81 cases with jaundice, 30.42 months was the average duration from the appearance of jaundice to the time at which the patient died or at which the last follow-up was performed. Approximatly two third of total number of patients died within the 1st 6 months. Afterwards the mortality rate was decreased markedly.In 111 cases of hepatic coma, 18.7 months was the average duration from appearing of hepatic coma to the time at which the patient died or at which the last follow-up was performed. The highest mortality rate occurred within the 1st 3 weeks after the appearance of hepatic coma, and was 82 percents. Afterwards the mortality rate was markedly decreased.Of the 235 cases died, account for 91% of the total number of patients of portal cirrhosis of liver hospitalized.The patients were still living up to the last follow-up in May 1980. Their survival duration were 22-31 years (average 25.6 years). All of their ascites and jaundice subsided, splenomegaly and liver function tests showed improvement. There were two factors responsible for the long survival time: (1) the prognosis was better in female patients than in male; (2) the cases with marked splenomegaly survived longer than those without marked splenomegaly. Our managements were dietary care, little drugs taken and not drinking alcohol. One patient had been operated upon with splenectomy.

    1.本文对245例门脉性肝硬化患者进行随访,观察期限最长者为31年。 2.自第一症状出现至死亡或随访时的平均病程为54.28月。第一症状出现后1年内死亡率最高,约近半数。以后则死亡率显著下降,且呈比较稳定的状态。 3.女性患者的预后较男性为佳,以脾肿大为开始的病例预后较好。 4.190例有腹水者,自腹水出现至死亡或随访的平均期限为31月。出现腹水后生存最久的病例为31年。腹水出现1年内的死亡率最高,已超过一半,此后则显著降低。 5.消化道大出血者130例,自第一次出血至死亡或随访之平均期限为34.39月。第一次出血8周内死亡率最高,超过一半,以后则显著下降。 6.81例有黄疸者,自黄疸出现至死亡或随访之平均期限为30.42月。黄疸出现半年内,约有2/3病例已经死亡,以后则死亡率大减。 7.肝昏迷患者111例,自昏迷出现至死亡之平均期限为18.7月。肝昏迷出现之3周内死亡率最高(82%)。此后则显著降低。 8.已经死亡之235例,其由肝病致死者为91%。

    The author presents here 48 cases of portal hypertension treated with splenorenal shunt from 1974 to 1983. All of them were of the intrahepatic type. 20 cases underwent elective, 4 emergency and 24 prophylactic shunts. The average postshunt portal pressure decrement was 105 mmH2O. There were 4 postoperative deaths ( mortality 8.3% with 2 deaths in emergency, and none in the prophylactic shunt group). Over all follow-up rate was 95.5% (42 cases), and periods from 8 months to 9.6 years. 6 cases died within 1-...

    The author presents here 48 cases of portal hypertension treated with splenorenal shunt from 1974 to 1983. All of them were of the intrahepatic type. 20 cases underwent elective, 4 emergency and 24 prophylactic shunts. The average postshunt portal pressure decrement was 105 mmH2O. There were 4 postoperative deaths ( mortality 8.3% with 2 deaths in emergency, and none in the prophylactic shunt group). Over all follow-up rate was 95.5% (42 cases), and periods from 8 months to 9.6 years. 6 cases died within 1- 6.8 years postoperatively. The absolute survival rates in 1, 3 and 5 years after operation were 93.2%, 78.5% and 72.7% respectively. There were 2 cases of rebleeding(4.8%) and 6 of encephalopathy (14.3%). Most of the ence-phalopathy cases responded well to protein restriction and intestinal antibiosis. The central splenorenal anastomosis is performed via the inferior margin of the pancreas by dissecting out the central segment of the splenic vein, which is then anastomosed to the left renal vein. The anastomosis thus made is near to the portal vein and the inferior vena cava. The operation is easy to perform giving a low incidence of re-bleeding and encephalopathy.

    1974~1983年,我院采用中央型脾肾静脉分流术治疗肝内型门脉高压症48例,其中急症手术4例,择期手术20例,预防性分流术24例。术后近期死亡4例(有2例作急症分流),随访42例,最长9年8个月,平均为4年。远期死亡率14.3%,再出血率4.8%;脑病发生率14.3%;康复率88.9%;绝对生存率1、3及5年分别为93.2、78.5及72.7%。此术式系经胃结肠韧带切开的途径暴露胰腺体部,掀起胰体前下缘,游离胰体后脾静脉中央段,使之与肾静脉吻合,优点为操作简便、出血少、吻合口较大血流通畅、降压效果好,平均降压105mmH_2O,再出血率较低,分流量因受肾静脉容量限制,故门脉血流对肝灌注影响不太大,脑病发生率未高出周围型脾肾静脉分流术。

    This paper we report 36 cases of liver disease with the serum levels ofT 3, T 4. In these cases with portal cirrhosis of the liver, serum T 3 wasow (mean valas of 0.78ng/ml, normal value of 1--2.28ng/ml). We fou-nd Vthat the less the serum levels of T 3 in cases with cirrhosis, the worsethe prognosis. But in acute hepatitis and chronic active hepatitis serumT 3 showed no significant change.

    本文报告了36例肝病患者血清T_3、T_4含量的改变,其中门脉性肝硬化及肝炎后肝硬化患者血清T_3含量明显降低(平均值0.78±0.29ng/ml),慢性活动性肝炎,急性病毒性肝炎患者血清T_3、T_4含量无明显改变,T_3含量的降低且与血清白蛋白含量及凝血酶原时间的延长呈正相关,若肝硬化患者T_3含量愈低者其预后亦愈差。

     
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