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基因
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  gene
    Apoptosis and Expression of Apoptosis Associated Gene in Smooth Muscle Cells of Autogenous Vein Graft in Rat Experimental Model
    移植静脉平滑肌细胞凋亡及相关基因表达与增殖关系的实验研究
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    Transcriptional modulationof alpha1(Ⅰ)procollagen gene in pathologic scar
    病理性瘢痕α1(Ⅰ)原胶原基因转录调控的实验研究
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    GDNF Gene Therapy for Spinal Cord Injury:An Experimental Study
    GDNF基因治疗大鼠脊髓损伤实验研究
短句来源
    Paclitaxel-induced apoptsis in human osteosarcoma cell line and the apoptotic effect of Caspase-6 gene
    紫杉醇诱导成骨肉瘤细胞凋亡及Caspase-6基因对成骨肉瘤细胞的凋亡诱导作用
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    Investigation of the Gene Expression of IGF-1,TGF-β_1,IL-6 and Biomechanics of Local Bone callus in Osteoporotic Fracture Healing
    骨质疏松骨折愈合过程中IGF-1、TGF-β_1、IL-6基因表达及骨痂局部生物力学的实验研究
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  genes
    The Study of Dynamic Expression of TNF-α and TNF-α R_1 Genes in Hypertrophic Scars and Its Significance
    TNFα及其受体基因在增生性瘢痕中的动态表达及其意义研究
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    Screening and Cloning the Genes Related to Heterogeneity of Traumatic Responses in the Interstrain Mice
    小鼠创伤反应异质性相关基因的筛选与克隆
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    Isolation and Identification of Differentially Expressed Genes in Human Osteoblast-like MG-63 Cell Induced by 17Beta-Estradiol
    雌二醇诱导人成骨样MG-63细胞差异表达基因的分离和鉴定
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    Cloning and Screening of Scarless Healing Related Genes in Fetal Rabbit Skin
    胎兔皮肤无瘢痕愈合相关基因的克隆及筛选
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    Expeimental Study on Adenoviral-Mediated Exogenous Genes Expression in Spinal Cords and Peripheral Nerves and Influencing Factor on the Transgene Expression
    腺病毒介导的外源性基因在脊髓和周围神经表达及其影响因素的实验研究
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  genetic
    Case-Control Study on the Associations of Genetic Polymorphisms of CYP1A1 MspⅠ, ER PvuⅡ and ER XbaⅠ with the Risk of Breast Cancer
    CYP1A1 MspⅠ、ER PvuⅡ、ER XbaⅠ基因多态性与乳腺癌关系的病例—对照研究
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    Congenital Dislocation of the Hip: Study of Genetic Epidemiology and Associations with HOXB9 and COL1A1 Genes
    先天性髋脱位的遗传流行病学研究以及与HOXB9基因和COL1A1基因的关联分析
短句来源
    The CYP1B1 which function as the susceptible genes to breast cancer has many genetic polymorphisms.
    该基因存在遗传多态性,目前已对CYP1B1基因多态性与乳腺癌易感性进行了多项研究。
短句来源
    The genetic cluster patterns could be divided into 10 types by RAPD gene typing.
    RAPD的基因分型得的遗传聚类图可分为10类。
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    Conclusions This study provides the first genetic evidence that the predisposing gene for this Han Chinese keloid pedigree may be mapped to the region about 1Mbp on chromosomes 10q23.31, between marker D10S1765 and D10S1735.
    结论我们的研究首次发现了该中国汉族瘢痕疙瘩家系的易感基因可能位于10q23.31上D10S1765与D10S1735两位点间约1Mbp区域的遗传学证据。
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  “基因”译为未确定词的双语例句
    Study on Molecular Chaperone ST13 and Hsp70 in Biological Features of Breast Cancer
    分子伴侣相关基因ST13和Hsp70对乳腺癌生物学特性影响的研究
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    HHK Artificial Tendon and Genetically Modified Mesenchymal Stem Cells for Tendon Repair
    HHK人工腱和基因修饰的间充质干细胞修复肌腱损伤
短句来源
    Effects of AdV/p75NTR Modified O2A Progenitor on Spinal Cord Injury in Adult Rats
    p75NTR基因修饰O2A祖细胞对成年大鼠损伤脊髓的修复作用
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    Wound Healing in CD36 Knock-out Mice
    CD36基因敲除小鼠的皮肤伤口愈合
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    Expression of Bone Morphogenetic Protein 4 in Normal Adult Mouse Kidney and Its Effect on Ischemia/Reperfusion Injury
    BMP4基因在肾脏中的表达及其对缺血/再灌注肾损伤的影响
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  gene
NEW TECHNOLOGY FOR DRUG DISCOVERY BASED UPON INSERTION OF LIGANDS INTO GENE SEQUENCES BY NUCLEAR RECEPTOR PROTEINS
      
A gene regulatory mechanism has been proposed in which steroid hormones and certain other drugs bind to nuclear receptor proteins followed by transfer to DNA where they are inserted between base pairs.
      
Polymerase chain reaction was used to amplify a 439-bp fragment of a 65,000-kDa (Mr) heat shock protein gene (hsp65) of Mycobacterium.
      
Cloning of an APETALA3 homologous gene (PtAP3) from Populus tomentosa and genetic transformation of its sense and anti-sense con
      
A pair of primers were designed according to published literature on Populus trichocarpa gene (PTD), and PtAP3, an AP3 homologous gene from Populus tomentosa was isolated by PCR using genomic DNA of the male clone of P.
      
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  genes
Simultaneous introduction of multiple genes into plants is a critical step in plant genetic engineering to manipulate multiple functional genes in metabolic engineering and trait stacking.
      
It is important to construct a bidirectional promoter for transforming two or more genes into plants simultaneously.
      
The transient expression of the gusA and gfp genes were detected by histochemical staining for GUS and by fluorescence microscopy for GFP.
      
At present, this procedure can be used to evaluate the genetic effect of individual major genes (up to two to three major genes), the collective genetic effect of polygene, and their heritability value.
      
Molecular mapping of two semidwarf genes in an indica rice variety Aitaiyin3 (Oryza sativa L.)
      
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  genetic
More particularly, Genetic Algorithms, Artificial Neural Networks and Fuzzy Logic methods seem to be the most promising tools to speed up and optimize the search for new leads and focused libraries.
      
Herein we describe the 3D QSAR study of 4-anilinoquinoline-3-carbonitrile by Genetic Function Approximation (GFA) and Comparative Molecular Field Analysis (CoMFA).
      
In this paper a hybrid algorithm which combines the pattern search method and the genetic algorithm for unconstrained optimization is presented.
      
The algorithm is a deterministic pattern search algorithm, but in the search step of pattern search algorithm, the trial points are produced by a way like the genetic algorithm.
      
Novel Quantum Genetic Algorithm and Its Applications
      
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The pathological findings in 9 cases of congenital situs in versus visoerum are reported. In the series, there were 7 cases with partial and 2 cases with complete transposition. Of the 9 cases, one was a 3 year old and one was an adult, 6 newborng lived only a few days after birth, one was a dead fetus, There were 3 males and 6 females. Of these cases, 7 were complicated with different other congenital malformations. The authors discussed the pathogenesis of congenital situs in versus viscerum which might differ...

The pathological findings in 9 cases of congenital situs in versus visoerum are reported. In the series, there were 7 cases with partial and 2 cases with complete transposition. Of the 9 cases, one was a 3 year old and one was an adult, 6 newborng lived only a few days after birth, one was a dead fetus, There were 3 males and 6 females. Of these cases, 7 were complicated with different other congenital malformations. The authors discussed the pathogenesis of congenital situs in versus viscerum which might differ in individual cases. Chromosomal studies were not done in these cases.

报道9例先天性内脏转位的病理发现。9例中部分性转位7例,完全性转位2例;生后数天的新生儿6例,死胎1例,3岁儿童1例,成人1例;女性6例,男性3例。9例中7例伴各种类型的先天性畸形。讨论了先天性内脏转位的发生机理,这在各病例可能并非绝对一致,但染色体基因变化似起一定的作用。

Mice inflicted with severe combined radiation-burn injury were treated with WR-2721 and allogenic fetal liver cell transplantation. The mortality of the treated group was significantly lower and the mean survival time longer than the control. When compared w'th those of the control, the changes of the per pheral white count, the count of the nucletaed cells of the bone marrow, and the bone marrow CFU-C of the treated group were less marked and returned to normal more rap:dly. The changes of the peripheral T-lymphocyte...

Mice inflicted with severe combined radiation-burn injury were treated with WR-2721 and allogenic fetal liver cell transplantation. The mortality of the treated group was significantly lower and the mean survival time longer than the control. When compared w'th those of the control, the changes of the per pheral white count, the count of the nucletaed cells of the bone marrow, and the bone marrow CFU-C of the treated group were less marked and returned to normal more rap:dly. The changes of the peripheral T-lymphocyte count was not so marked as that of the bone marrow CFU-C.The combined therapeutic efficacy of WR-2721 and fetal cell transplantation was more prominant in treating the combined radiation and burn injury than either of the two agents used alone.

重度放射损伤复合重度烧伤小鼠伤前给WR-2721[S-2(3-氨丙基氨基)乙基硫代磷酸]预防,伤后输注1×10~6同种异基因胎肝细胞悬液治疗,能明显降低动物死亡率,延长死亡动物平均活存日。与对照动物相比,外周血白细胞计数、骨髓有核细胞总数、骨髓CFU-C(粒系造血干细胞)损伤轻、恢复快。外周血酯酶染色的T淋巴细胞计数改变不如骨髓CFU-C变化明显。输注胎肝治疗合并应用辐射防护剂WR-2721对重度放射损伤复合重度烧伤的效果,超过单用胎肝细胞输注或WR-2721的效果。

Immobilization is a effective treatment method in orthopedics and trauma. Athough used widely, it could cause lofs of bone. Twelve mature rabbits of mixed sex weighting from 2.8 to 3 Kg were used in the experiment. The left hind limb cast in a cylindrial extending from just below the inguinal region to the ankle with the knee flexed at a 30 degree angle, the right hind limb of the same rabbit served as a control. The rabbits could move freely in the trunk. After 7 weeks, all rabbits were sacrificed. Bilateral...

Immobilization is a effective treatment method in orthopedics and trauma. Athough used widely, it could cause lofs of bone. Twelve mature rabbits of mixed sex weighting from 2.8 to 3 Kg were used in the experiment. The left hind limb cast in a cylindrial extending from just below the inguinal region to the ankle with the knee flexed at a 30 degree angle, the right hind limb of the same rabbit served as a control. The rabbits could move freely in the trunk. After 7 weeks, all rabbits were sacrificed. Bilateral tibia and the second metatarsus were moved out and rejected all connective tissue. Bone mineral content(BMC)and bone density(BMC/BW)of bilateral tibia were measured with SPA—Ⅲ bone mineral analysis instrument. BMC, BMC/BW, bone cortical width (BC1, BC2), bone length and volume of the bilateral second metatarsus were measured. The results show that BMC and BMC/BW in middle tibia and significant difference (P<0.01) comparing experiment group with control one and there was difference (P<0.05) in one—third lower tibia between two groups. The length and volume of the Second metatarsus have difference(P<0.05, 0.01 respect—ively), and it not there difference(P>0.05)in bone width. There were difference (P<0.05, 0.01) in BC1, BC2 and BMC/BW. It is concluded that immlbilization could cause loss of bone mass and decreased of BMC, and lower O_2 and active muscles exercise of metatarsophalangeal joint could prevent loss of bone mass.

石膏制动作为骨科治疗中的一个重要措施,广泛应用于临床。但制动可以导致骨的丧失。本文对12只成年家兔左侧肢体从后肢自腹股沟至踝关节,作膝关节屈曲30°石膏管型固定。以对侧肢体作正常对照组。施以标准化饲养喂养,在笼中可以自由活动。经7周后,12只动物一次性处死。取其双侧胫骨,第二跖骨,剔除周围的软组织。运用SPA—Ⅲ骨矿分析仪对双侧胫骨宽度(BW),骨矿物质含量(BMC)骨面密度(BMC/BW)测定,并对双侧第二跖骨骨体积,骨长度,骨皮质厚度(BC1,BC2),BMC及BMC/BW进行测定六次,取平均值。结果表明,胫骨中段BMC及BMC/BW制动组与正常对照组比较有显著性差异(P<0.001);在胫骨中下1/3处BMC和BMC/BW中,两组间亦有差异(P<0.05)。对第二跖骨骨长度及骨体积测量,制动组比对照组增长且体积增大,两者之间有显著性差异(P<0.001),而骨宽度两组之间无差异(P>0.05);骨皮质BC1,BC2两组间比较有显著性差异(P<0.01);BMC和BMC/BW,两组间亦有差异(P<0.05,0.01)。从结果可看出,超关节石膏固定,可使局部骨矿物质含量下降,骨内脱钙比较明显。在肢体远端,由...

石膏制动作为骨科治疗中的一个重要措施,广泛应用于临床。但制动可以导致骨的丧失。本文对12只成年家兔左侧肢体从后肢自腹股沟至踝关节,作膝关节屈曲30°石膏管型固定。以对侧肢体作正常对照组。施以标准化饲养喂养,在笼中可以自由活动。经7周后,12只动物一次性处死。取其双侧胫骨,第二跖骨,剔除周围的软组织。运用SPA—Ⅲ骨矿分析仪对双侧胫骨宽度(BW),骨矿物质含量(BMC)骨面密度(BMC/BW)测定,并对双侧第二跖骨骨体积,骨长度,骨皮质厚度(BC1,BC2),BMC及BMC/BW进行测定六次,取平均值。结果表明,胫骨中段BMC及BMC/BW制动组与正常对照组比较有显著性差异(P<0.001);在胫骨中下1/3处BMC和BMC/BW中,两组间亦有差异(P<0.05)。对第二跖骨骨长度及骨体积测量,制动组比对照组增长且体积增大,两者之间有显著性差异(P<0.001),而骨宽度两组之间无差异(P>0.05);骨皮质BC1,BC2两组间比较有显著性差异(P<0.01);BMC和BMC/BW,两组间亦有差异(P<0.05,0.01)。从结果可看出,超关节石膏固定,可使局部骨矿物质含量下降,骨内脱钙比较明显。在肢体远端,由于静脉淤滞,PH降低,骨内压增高,骨组织处在缺氧情况下,刺激了骨膜成骨,促进骨生长,可见到骨体积长度增大,骨皮质增厚,另外,局部CO_2增高,可以直接做为成骨细胞调节基因的诱异物,促进骨生长,再加之跖骨及趾骨在石膏外可做一定程度的运动,这些都可以促进骨钙沉积,骨矿质增高。

 
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