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卵巢癌
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  ovarian cancer
    The Study of Chinese Medicine Arsenictrioxide (AS_2O_3)'s Effect on Ovarian Cancer in Vitro and Liver Cell Growth Factor Expiession
    中药砒霜(AS_2O_3)在卵巢癌体外作用及肝细胞生长因子表达的研究
短句来源
    Study of Three Root Anticancer Prescription on Inhibitory Effect on Ovarian Cancer Cell Lines HO-8910
    三根祛瘤方对人卵巢癌细胞HO—8910抑制作用的研究
短句来源
    STUDIES OF GFW ON INDUCING APOPTOSIS IN OVARIAN CANCER CELL LINES HO8910
    桂枝茯苓丸诱导卵巢癌HO8910细胞凋亡的研究
短句来源
    Progress on the Study of Mechanism of the Direct Action of TCM Bioactive Components on Ovarian Cancer
    中药活性成分对卵巢癌的直接作用机制研究进展
短句来源
    The inhibitory role of wogonin on tumor growth and telomerase activity of human ovarian cancer SKOV3 cell line xenograf in nude mice
    汉黄芩素对人卵巢癌细胞株SKOV3裸鼠移植瘤生长及端粒酶活性的抑制作用
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  ovarian carcinoma
    Objective: To investigate the inhibitory effect of resveratrol on the metastasis-associated ability of human highly metastatic ovarian carcinoma HO-8910PM cells in vitro.
    目的:研究白藜芦醇对人高转移卵巢癌细胞HO-8910PM转移相关能力的影响。
短句来源
    Study on the Effect of Resveratrol on Metastasis-associated Ability of Ovarian Carcinoma HO-8910PM Cells in Vitro
    白藜芦醇影响高转移卵巢癌细胞HO-8910PM转移相关能力的实验研究
短句来源
  ovarian tumor
    The Experiment Research in Ovarian Tumor Cells CAOV3 by Ya-Dan-Zi Oil Vein Emulsion
    中药鸦胆子油静脉乳剂对卵巢癌细胞株CAOV3作用的实验研究
短句来源
    Conclusion: Ya-Dan-Zi oil vein emulsion promotes change in morphology, comes down enzyme activation and ability of invasion and metastasis,induces apoptosis of ovarian tumor cells.
    结论:鸦乳剂促进卵巢癌细胞形态学改变,诱导癌细胞凋亡,降低Mg~(2+)-ATPase和G-6-Pase的酶活性,降低癌细胞侵袭和转移能力。
短句来源
  “卵巢癌”译为未确定词的双语例句
    Experimental Study of Antitumor Effect of Chinese Herbal Prescription "Niu Huang Tian Long Yin" on Apoptosis of SK Tumor Cell and S-180 Tumor Cell
    复方中药牛黄天龙饮对人卵巢癌SK细胞和小鼠肉瘤S-180细胞抗肿瘤作用的实验研究
短句来源
    Conclusions As2O3 can inhibit growth of SKOV3 and induce apoptosis of it.
    结论 As_2O_3对卵巢癌细胞株SKOV_3的生长有明显的抑制作用,诱导凋亡是其主要作用机制之一。
短句来源
    Objective To investigate the synergistic effects on cell apoptosis and growing restriction of SKOV3 cells by the combination of compound herbal medicinal prescription(CHMP) with cisplatin(DDP).
    目的观察抗癌中药复方(CHM P)药血清及其协同顺铂(DDP)对卵巢癌细胞SKOV 3的增殖及凋亡的影响,分析补益(CHM P1)与解毒化瘀(CHM P2)复方在体外对顺铂协同作用的最佳搭配方式及其机制。
短句来源
    The Effect and Mechanism of Kang Ai Ning to Ovary Tumor Cell Activity
    抗癌宁对卵巢癌细胞活性的影响及作用机制
短句来源
    5. Kang Ai Ning E can associate with cisplatin to inhibit ovary tumor growth.
    5、抗癌宁E药物具有协同顺铂抑制肿瘤卵巢癌细胞作用。
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  ovarian cancer
Of them, α-1-acid glycoprotein and clusterin are expressly down-regulated in breast cancer, whereas transthyretin is decreased specifically in ovarian cancer.
      
BRCA1 mutations are associated with a higher risk of breast (BC) and ovarian cancer in women.
      
Biochip analysis of BRCA1/2 and CHEK2 common mutations in ovarian cancer and primary multiple tumors involving the ovaries (Russ
      
Ovarian cancer (OC) is among the leading causes of cancer-related mortality in women.
      
The RA538 cDNA was transferred into human ovarian cancer cell line SK-OV-3 and human melanoma cell line WM-983A by its recombinant adenoviral vector constructed through homologous recombination.
      
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  ovarian carcinoma
Semiquantitative RT-PCR revealed elevated transcription of RHOA in tumors (45 cases of breast cancer, renal cell carcinoma, and epithelial ovarian carcinoma; p >amp;lt; 10-4).
      
20,29-Dihydro-20,29-dichloromethylenebetulinic acid proved to be the most cytotoxic toward human melanoma of the Colo 38 and Bro lines and human ovarian carcinoma of the CaOv line (IC50 10 μM).
      
Expression of the human fast-twitch skeletal muscle troponin I cDNA in a human ovarian carcinoma suppresses tumor growth
      
To explore the efficiency and mechanism of ovarian carcinoma gene therapy with the human fast-twitch skeletal muscle troponin I gene (Tnl-fast), Tnl-fast cDNA was transferred into human ovarian adenocarcinoma cell-line SK-OV-3.
      
Our study, to our knowledge, shows the slowed down growth of the primary ovarian carcinoma, suggested that grafts were self-inhibitory by halting angiogenesis.
      
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  ovarian tumor
The thermostable fraction of serum samples from patients with ovarian, uterus, and breast cancers and benign ovarian tumor was analyzed using two-dimensional electrophoresis combined with MALDI-TOF(-TOF)-mass spectrometry.
      
Clinical diagnosis and treatment of small ovarian tumor in postmenopausal women
      
The Cx43 expression was detected by flowcytometry, Western, blot, and immunofluorescence in two ovarian tumor cell lines OVCAR3, CaOV3 before and after RA treatment.
      
Construction of human ScFv phage display library against ovarian tumor
      
Human ScFv library against ovarian tumor was constructed successfully, which laid a foundation for the screening of ovarian tumor specific ScFv for the radioimmunoimaging diagnosis of ovarian tumor.
      
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Objective:To evaluate the efficacy and toxicity of paclitaxel in patients with a variety of malignancies.Methods:Paclitaxel was administered as a single agent at a dose of 175 mg/m 2 or in combination chemotherapy at a dose of 135 mg/m 2 by 3 hour iv infusion every three weeks.All patients received premedication (dexamethasone,diphenhydramine,and cimetidine)to prevent hypersensitivity reactions.Results:Three hundred and thirty three patients were entered into this study.167 patients were treated with paclitaxel...

Objective:To evaluate the efficacy and toxicity of paclitaxel in patients with a variety of malignancies.Methods:Paclitaxel was administered as a single agent at a dose of 175 mg/m 2 or in combination chemotherapy at a dose of 135 mg/m 2 by 3 hour iv infusion every three weeks.All patients received premedication (dexamethasone,diphenhydramine,and cimetidine)to prevent hypersensitivity reactions.Results:Three hundred and thirty three patients were entered into this study.167 patients were treated with paclitaxel single agent therapy and 166 patients were treated with paclitaxel combined with cisplatin or doxorubicin or other chemotherapeutic agents.Responses were observed in patients receiving paclitaxel treatment alone,with the overall response rate for ovarian cancer being 37%,breast cancer 39%,non small cell lung cancer 31%,small cell lung cancer 40%, and nasopharyngeal cancer 67%.Responses were also achieved in patients receiving paclitaxel combination chemotherapy,with the overall response rate for ovarian cancer being 38%,breast cancer 44%,non small cell lung cancer 31%,small cell lung cancer 40%,and nasopharyngeal cancer 44%.The major toxicity associated with paclitaxel included neutropenia,myalgia and arthralgia,peripheral neuropathy,and alopecia.Conclusion:At this dose and schedule,paclitaxel is well tolerated and has notable antitumor activity.Paclitaxel may be combined with other chemotherapeutic agents for the treatment of cancer patients.

目的考察紫杉醇治疗多种恶性肿瘤的疗效及毒副作用。方法紫杉醇单药化疗每次剂量175mg/m2,联合化疗紫杉醇每次剂量135mg/m2,3h静脉输注,每3周重复,在紫杉醇治疗前常规给予地塞米松、苯海拉明和西米替丁预防过敏反应。结果共333例进入了临床研究。167例接受了紫杉醇单药化疗,166例接受了紫杉醇加顺铂或阿霉素或其他药物联合化疗。紫杉醇单药化疗的有效率如下:卵巢癌37%,乳腺癌39%,非小细胞肺癌31%,小细胞肺癌40%,鼻咽癌67%。紫杉醇联合化疗的有效率如下:卵巢癌38%,乳腺癌44%,非小细胞肺癌31%,小细胞肺癌40%,鼻咽癌44%。患者毒副反应主要为白细胞减少、肌肉及关节疼痛、感觉异常和脱发。结论本研究所用的紫杉醇制剂及剂量安全有效,患者能够耐受。紫杉醇可与其他化疗药物联合应用,治疗恶性肿瘤病人。

PANG Pan chi(1919—1999),female,a native of Shanghai,a professor in Shanghai University of Traditional Chinese Medicine and a Shanghai famous physician of Chinese medicine,was engaged in Chinese internal and gynecological medicine for over 50 years,and was one of the forerunners in the development of the treatment and experimental study of tumors by integration of Chinese and western medicine in the domestic circle of Chinese medicine after liberation...

PANG Pan chi(1919—1999),female,a native of Shanghai,a professor in Shanghai University of Traditional Chinese Medicine and a Shanghai famous physician of Chinese medicine,was engaged in Chinese internal and gynecological medicine for over 50 years,and was one of the forerunners in the development of the treatment and experimental study of tumors by integration of Chinese and western medicine in the domestic circle of Chinese medicine after liberation and was skillful in the treatment of intractable gynecological diseases of malignant tumors and sterility.Two proven cases respectively about “Prevention of Recurrence and metastasis after Oophoroma Operation”and “Sterility due to Obstruction of Fallopian Tube”were listed.

庞泮池(1919-1999),女,上海市人。上海中医药大学教授,上海市名中医。从事中医内、妇科临床50余年,是解放后国内中医界较早与西医合作,开展肿瘤治疗和实验研究的先行者之一。擅长中医药和中西医结合治疗妇科恶性肿瘤和不孕症等妇科疑难病证。附“卵巢癌术后防复发转移”及“输卵管阻塞性不孕”验案各一则。

Both the morbidity and mortality of ovarian cancer, among malignant tumors of female genital organs, are quite high. The traditional therapeutic methods on ovarian cancer are surgical operation, chemotherapy, radiotherapy and combination of these methods mentioned above. In recent years, some components of traditional Chinese medicine, such as genistein, semen Coicis,phytosterols,curcumin,quercetin,ginsenoside, etc. have been found to exert anticancer actions of inhibiting proliferation and inducing apoptosis...

Both the morbidity and mortality of ovarian cancer, among malignant tumors of female genital organs, are quite high. The traditional therapeutic methods on ovarian cancer are surgical operation, chemotherapy, radiotherapy and combination of these methods mentioned above. In recent years, some components of traditional Chinese medicine, such as genistein, semen Coicis,phytosterols,curcumin,quercetin,ginsenoside, etc. have been found to exert anticancer actions of inhibiting proliferation and inducing apoptosis of cancer cells,increasing the sensitivity of patients to chemotherapeutic agents in vivo and/or in vitro, the mechanisms involve such aspects as inhibiting activity of key enzymes in cell metabolism, affecting gene expression, antioxidation,and inhibiting tumor angiogenesis, etc. As an adjuvant therapeutic means, the bioactive components of traditional Chinese Medicine have broad future of clinical application.

卵巢癌在女性生殖器官恶性肿瘤中的发生率及病死率均较高,传统的治疗手段包括手术治疗、化学药物治疗(化疗)、放射线治疗及上述治疗方式的联合应用。近年来发现我国传统中药成分如金雀黄素、薏苡仁、植物固醇类、姜黄素、五羟黄酮、人参皂苷等可在体内和(或)体外发挥对卵巢癌细胞的抑制增殖、诱导凋亡、增加对化疗药物的敏感性等抗癌作用。其作用机制涉及到抑制细胞代谢关键酶活性、影响细胞基因表达、抗氧化、抑制肿瘤新生血管形成等方面,其作为卵巢癌的一种辅助治疗手段,有着广阔的临床应用前景。

 
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