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肌膜     
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  sarcolemma
     In the study group, 1 mL (300 ng) exogenous insulin-like growth factor-Ⅱ was injected into the inferior sarcolemma in the middle of right gastrocnemius muscle on the 1st, 3rd and 5th days after the first exhaustion respectively.
     首次力竭后第1,3,5天实验组于右侧腓肠肌中部的肌膜下分别注射1mL(300ng)外源性胰岛素样生长因子Ⅱ;
短句来源
     Na~+-K~+-ATPase on Skeletal Sarcolemma and Peripheral Fatigue
     肌膜Na~+,K~+-ATP酶与骨胳肌运动能力
短句来源
     Effect of Anisodamine, Verapamil and Endotoxin on Na~+- Ca~2+Exchange Activity of Canine Cardiac Sarcolemma in Reconstituted Liposomes
     山莨菪碱、异搏定、内毒素对重组脂质体上心肌肌膜Na~+-Ca~(2+)交换活性的影响
短句来源
     The effects of sodium selenite(Se) on the dynamic changes of Ca~2+-ATPase activity of Mitochondria(Mit),Sarcoplasmic reticulum(SR) fractions at 30,60 and 90min after ischemia were determined,and the changes of the Na~+-K~+-ATPase activity of sarcolemma(SL) and Mit phospholipid contents after 60min ischemia MI,MI+Se rat hearts were observed.
     观察硒对心肌缺血后30、60、90min肌浆网(SR)、线粒体(Mit)Ca2+-ATP酶活性动态变化及缺血60min肌膜(SL)Na+-K+-ATP酶活性和线粒体膜磷脂含量变化的影响。
短句来源
     The mechanisms of redistribution of the calcium channels in the sarcolemma and the light vesicle during sepsis was not associated to the phosphorylation of the calcium channels by cAMP dependent protein kinase (PKA),Ca(2+)/calmodulin dependent protein kinase (PKM) and protein kinase C (PKC).
     败血症时大鼠心肌肌膜和心肌轻型囊泡钙通道的再分布与cAMP依赖性蛋白激酶(PKA),Ca(2+)/钙调素依赖性蛋白激酶(PKM)和蛋白激酶C(PKC)磷酸化作用无关。
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  tunica muscularis
     A incision was made on the inner lateral tunica muscularis of semitendinosus to embed all free branches of broken end into the muscle. The perilemma and tunica muscularis were sutured to fix,and rats in the experiment group were injected with 0.1 mL of OECs (1×109 L-1) at the muscle 2 mm away from the bilateral parts of incision. Rats in the blank control group were injected with cell culture fluid DMEM.
     ①对照组与实验组大鼠在坐骨切迹处游离坐骨神经的各分支,在远端切断,在半腱肌内侧肌膜上切口,将坐骨神经近断端的各游离分支包埋进肌肉,神经外膜与肌膜缝合固定,实验组在缝合口两侧2mm处肌肉中各注射1×109L-1的嗅鞘细胞0.1mL,对照组注射细胞培养液DMEM。
短句来源
     ⑤At 12 weeks after denervation,most of the muscle fibers degenerated but no normal muscle fibers could be found,and the cell nucleus of muscle fibers situated in the periphery,which had well contract system. The fibers were in order arrangement with clear Z line and complete tunica muscularis.
     ⑤失神经支配12周,大部分肌纤维萎缩退行性变,但是仍可发现没有萎缩的肌纤维,这些肌纤维细胞核位于周边,有良好的收缩系统,纤维排列规则,Z线清晰,有完整的肌膜
短句来源
     ⑥ At 16 weeks after denervation,the satellite cells decreased greatly,and a great amount of fine fibers could be found,most of which surrounded some larger muscle fibers with integrate and smooth tunica muscularis without reductus.
     ⑥失神经支配16周,肌卫星细胞的数量明显减少,并可发现大量细小的肌纤维,多分布在较大的肌纤维附近,肌膜完整平滑,无皱褶。
短句来源
  sarcolemmal
     The present work studied the effects of calcitonin gene-related peptide (CGRP), vasoactire intestinal peptide (VIP), atrial natriuretic peptide (ANP), substance P (SP) and substance K (SK) on Na~+-Ca~(2+) exchange in reconstituted liposomes with canine sarcolemmal Na~+-Ca~(2+) exchange protein.
     本实验在狗心肌肌膜Na~+-Ca~(2+)交换蛋白重组的人工生物膜脂质体上,观察降钙素基因相关肽(CGRP)、血管活性肠肽(VIP)、心房肽(ANP)、P物质(SP)和K物质(SK)对Na~+-Ca~(2+)交换蛋白活性的影响。
短句来源
     Sarcolemmal K~+_ ATP channel blocker HMR1098 (30 μmol/L) and mitochondral K~+_ ATP channel blocker 5-hydroxydecanoate (5HD, 500 μmol/L) were included in the perfusing solution for some experiments.
     选用特异性心肌肌膜KA+TP阻断剂HMR109830μmol/L和特异性心肌线粒体KA+TP阻断剂5HD500μmol/L。
短句来源
     Sarcolemmal Ca~(2+)-ATPase activity can be observed in cerium-based method (pH 7.4). but can not be seen in the lead-based method (pH8.8-9.0).
     将孵育液pH由铅法的8.8~9.0改为7.2~7.4,能显示肌膜Ca~(2+)-ATP酶的活性。
短句来源
     The rat cardiac sarcolemmal PKC activation and AC sensitization durlug ES is related to M-cholinergic receptor system.
     ES大鼠心肌肌膜PKC的激活和AC的增敏与M-胆碱受体系统有关;
短句来源
     Magnesium is an essential cofactor of the sarcolemmal ATPase. A variation in the medium Mg2+concentration from 0 to 6 mM gives a dose-dependent change in activity of the enzyme system. When Mg2+ concentration is above 8 mM, it increases the activity due to Na++K++Mg2+.
     本工作在大鼠心肌肌膜观察到,Mg~(2+)为心肌Na~+-K~+-ATP酶激活所不可缺少的因素,当Mg~(2+)浓度在0~6mM时,Na~+-K~+-ATP酶及Mg~(2+)-ATP酶活性与其密切相关;
短句来源
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  muscle membrane
     Relationship between anti-eye muscle membrane antibody and TSH receptor antibody in serum from patient with Graves ophthalmopathy
     Graves眼病患者血清抗眼肌膜抗体与TSH受体抗体的关系
短句来源
     DNA Binding Protein in Skeletal Muscle Membrane
     骨骼肌膜DNA结合蛋白
短句来源
     Objective To evaluate the effects of anti eye muscle membrane antibody and TSH receptor antibody(TRAb) in the immune pathogenesis of Graves ophthalmopathy (GO).
     目的 评价抗眼肌膜抗体和TSH受体抗体(TRAb)在Graves眼病(GO)免疫发病中的作用。
短句来源
     Objective Studying the relationship between eye muscle membrane antibody ( E M Ab)and Graves’ophthalmopathy ( G O) and its clinicalsignificance .
     目的 探讨抗眼肌膜抗体( E M Ab) 与 Graves 眼病的关系及其临床意义。
短句来源
     Affinity chromatography of human eye muscle membrane proteins to pooled IgG from patients with GO followed by SDS-polyacrylamide gel electrophoresis (SDS-PAGE) Ied to the appearance of proteins with molecular weights of about 45 kD, 28 kD, 55 kD,and 64 kD (especially the firot two), which were not present in the chromatography to pooled IgG from the controls.
     人眼肌膜蛋白经GO患者混合IgG亲和层析后进行SDS-聚丙烯酰胺凝胶电泳,显示分子量为45、28、55和64kD等蛋白条带。 经正常人混合IgG亲和层析未能显示上述结果。
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  sarcolemma
With increasing energy deficiency the cardiac sarcolemma loses its ability to retain macromolecules (myoglobin, enzymes) within the cell.
      
It is well documented that changes in contractility of the heart can originate from alterations at the level of the sarcolemma and the intracellular Ca2+ stores.
      
Negatively charged sites and calcium binding in the isolated rat heart sarcolemma*
      
Colloidal iron staining, calcium binding and enzyme activities were studied in the isolated rat heart sarcolemma.
      
Colloidal iron staining of the sarcolemma revealed a high density of negatively charged sites associated with the cell surface.
      
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  tunica muscularis
Repeated endoscopic biopsies did not reveal the histologic diagnosis, although endoscopic ultrasound invasion to the tunica muscularis could not be excluded.
      
Die Entstehung einer vorzugsweise auf das Antrum beschr?nkten Hypertrophie der Tunica muscularis propria im Tierversuch wird besprochen.
      
5-Hydroxytryptamine4 receptors mediate relaxation of the rat oesophageal tunica muscularis mucosae
      
The present study was designed to characterize an "atypical" 5-hydroxytryptamine (5-HT) receptor mediating relaxation of the rat oesophageal tunica muscularis mucosae.
      
Concentration-effect curves to 5-HT were not affected by tetrodotoxin or indomethacin, sugesting that 5-HT-induced relaxation of the tunica muscularis mucosae was mediated via a postjunctional receptor, independent of endogenous prostanoids.
      
更多          
  sarcolemmal
The treatment of sarcolemmal membrane fraction with cholera toxin increases basal adenylate cyclase activity and decreases the sensitivity of the enzyme to insulin.
      
Reperfusion, as evidenced by the influx of HRP into the damaged cells, unmasked sarcolemmal membrane injury.
      
The decrease in sarcolemmal Na+-K+ ATPase activity was associated with contractile failure and preceded the observed decrease in myocardial K+ and increase in Na+ contents.
      
Decreases in sarcolemmal, mitochondrial and myofibrillar ATPase activities as well as sarcolemmal adenylate cyclase activity were observed in late stages of bacterial endocarditis, at which time extensive myocardial cell damage was also apparent.
      
The effect of a calcium channel antagonist, Nisoldipine, on the ischemia-induced change of canine sarcolemmal membrane
      
更多          
  muscle membrane
an enhancement of coronary vascular smooth muscle membrane permeability to calcium ions.
      
Sodium channels from human ventricular muscle membrane vesicles were incorporated into planar lipid bilayers and the steady-state behavior of single sodium channels were examined in the presence of batrachotoxin.
      
This might be the mechanism by which potassium is released from muscle cells into the circulation and muscle membrane excitability is restored.
      
Myoglobin is a sensitive marker of increased muscle membrane vulnerability
      
Changes in muscle proteins in serum after exercise were studied to evaluate the use of such proteins as indicators of increased muscle membrane vulnerability.
      
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  其他


Serial sections of musculus rectus lateralis in the eyes of the cat, stained with Glee's silver imp-regnation for paraffin method, were used for this study. A great number of nerve endings were found in the extrinsic eye muscles, far more than thosewhich found in the musculus lumbricales. A few muscle spindles were found. Near the tendon ofthis muscle. The spiral nerve endings and the grape-like endings were also found on the muscle fibers.A few arboreal sensory endings, sensory spools and free sensory endings...

Serial sections of musculus rectus lateralis in the eyes of the cat, stained with Glee's silver imp-regnation for paraffin method, were used for this study. A great number of nerve endings were found in the extrinsic eye muscles, far more than thosewhich found in the musculus lumbricales. A few muscle spindles were found. Near the tendon ofthis muscle. The spiral nerve endings and the grape-like endings were also found on the muscle fibers.A few arboreal sensory endings, sensory spools and free sensory endings could be located in the in-tramuscular connective tissue. The end-plates of the musculus rectus lateralis of the cat may be divided into four-types: the dichotomous end-plate, arboreal end-plate, flowr-like end-plate and claw-like end-plate.A few ultraterminal endings were likewise found in it.

作者在用石蜡镀银法染色的猫眼外直肌的切片中,观察到下列的结果: 1.猫眼外直肌内有丰富的神经末梢。在单位面积中,神经末梢的数量比它的蚓状肌要多得多。 2.猫眼外直肌运动终板的大小和形状有很大的差异。根据形状可分为叉状运动终板、树枝状运动终板、花瓣状运动终板和爪状运动终板四种类型。少数已有运动终板的肌纤维,尚接受副末梢的供给。 3.和运动纤维伴行的细纤维,一部分是运动纤维的分支,它们参与运动终板的组成。有一些细纤维除开分支组成运动终板外,其本干穿出运动终板,末端形成梭状肿大,终止于其他的肌纤维。 4.猫眼外直肌的两端,紧靠肌腱的附近,存在着少数形态较简单没有结缔组织膜包被的肌膜。 5.猫眼外直肌内有很丰富的感觉末梢。葡萄状感觉末梢的数量最多,是眼外直肌最主要的本体感觉末梢;并且还有少量的肌梭和螺旋状感觉末梢。在结缔组织中,有游离感觉末梢、丝球状感觉末梢、树枝状感觉末梢和芽状感觉未梢。 6.Marsland,Glees和 Erikson的石蜡镀银法,是一个较简便而稳定的神经末梢的染色法。

It is generally accepted that the change of Ca ion concentration in sarcoplasm, which is regulated by the sarcoplasmic reticulum in the skeletal muscle cell, is the key linkage in the process of excitation-contraction coupling. In the case of frog cardiac cell, the sarcoplasmic reticulum is poorly developed, the T-tubule may be absent completely and the diameter of the cell is rather small, thus it has been repeatedly proposed that in such muscle cell, the sarcoplasmic Ca ion concentration may be controlled...

It is generally accepted that the change of Ca ion concentration in sarcoplasm, which is regulated by the sarcoplasmic reticulum in the skeletal muscle cell, is the key linkage in the process of excitation-contraction coupling. In the case of frog cardiac cell, the sarcoplasmic reticulum is poorly developed, the T-tubule may be absent completely and the diameter of the cell is rather small, thus it has been repeatedly proposed that in such muscle cell, the sarcoplasmic Ca ion concentration may be controlled by the processes occurring in the sarcolemma. In this article a quantitative test of the possibility of such supposion is made. Assume that the increase of intracellular Ca ion concentration during activity is due simply to the inward transmembrane diffusion of the ions down their concentration gradient from the extracellular fluid into the cell and the decrease of concentration is attributed to a certain carrier involved active membrane process. The latter process may be expressed as Based on above assumptions, the successive values of the intracellular Ca ion concentration during the course of repeatitive stimulation at a given frequency and the asymptotic steady valves of concentration under different stimulus frequencies have been calculated and then are compared with the experimental results of "staircase" phenomenon by making use of the known relation between the sarcoplasmic Ca ion concentration and the steady contractile force developed. Fairly good agreement has been obtained within quite a wide range of stimulus frequencies. It is entirely possible that the sarcolemma of frog cardiac cell plays a crucial role in the regulation of sarcoplasmic Ca ion concentratiom even in the view of quantitative consideration.

在骨胳肌兴奋-收缩耦联过程中,肌浆钙离子浓度主要由肌浆网系调节。青蛙心肌细胞的肌浆网系不发达,没有横管,且细胞直径很小,因此肌浆钙离子浓度很可能由发生在肌膜上的过程调节。本文从定量角度验证这一设想的可能性。假定青蛙心肌细胞兴奋时钙离子顺浓度差从细胞外跨膜扩散入细胞使肌浆钙浓度升高,又经肌膜上类似载体作用的主动过程将钙离子排出细胞,由此计算静息蛙心肌在某一频率的重复刺激下肌浆钙离子浓度随刺激次数的变化以及对不同刺激频率当收缩张力达稳态时肌浆内钙浓度值。利用肌肉稳态收缩张力和细胞内钙离子浓度之间已知的单值关系可以看到,计算结果同实验记录的蛙心肌稳态张力与刺激频率间的“阶梯”关系符合得很好,说明青蛙心肌细胞膜在调节肌浆钙离子浓度中起决定作用这一想法从定量角度考虑也完全是可能的.

The snake venom of the Bungarus fasciatus was fractionated on CM-SephadexC-50 column into sixteen fractions.The peaks Ⅷ,Ⅹ,Ⅷ,ⅩⅣ,ⅩⅤ,ⅩⅥ werelethal.Effects of peaks Ⅹ,Ⅷ,ⅩⅣ,ⅩⅥ,on the miniature end-plate potentials,end plate potentials and muscular membrane potentials of the rat phrenic-diaphragmand other neuromuscular preparations were studied.Effects of these fractions on thesensitivity of the isolated denervated muscles to acetylcholine were also observed.Itwas suggested that peaks ⅩⅣ and ⅩⅥ containing neurotoxic...

The snake venom of the Bungarus fasciatus was fractionated on CM-SephadexC-50 column into sixteen fractions.The peaks Ⅷ,Ⅹ,Ⅷ,ⅩⅣ,ⅩⅤ,ⅩⅥ werelethal.Effects of peaks Ⅹ,Ⅷ,ⅩⅣ,ⅩⅥ,on the miniature end-plate potentials,end plate potentials and muscular membrane potentials of the rat phrenic-diaphragmand other neuromuscular preparations were studied.Effects of these fractions on thesensitivity of the isolated denervated muscles to acetylcholine were also observed.Itwas suggested that peaks ⅩⅣ and ⅩⅥ containing neurotoxic components actingpostsynaptically,peak Ⅹ containing cytotoxic and peak Ⅷ containing cytotoxic andpresynaptic components.By rechromatography on Bio Rex-70 column,a postsynaptioneurotoxin was purified from peak ⅩⅣ and a cytotoxin was purified from peakⅩⅢ.Both of them gave a single band by disk gel polyacrylamide eletrophoresis in8 M urea.Their molecular weights were 13,200 for the cytotoxin and 7,900 for thepostsynaptic neurotoxin by gel filtration.Their minimum lethal doses determinedby intravenous injection into mice were 4.μg/g and 0.16μg/g respectively.

金环蛇毒经羧甲基-葡聚糖凝胶C-50柱层析分离为几个主峰,其中Ⅷ、Ⅹ、ⅩⅢ、ⅩⅣ、ⅩⅤ及ⅩⅥ六个峰为主要致死成分。在大白鼠膈神经-膈肌及其他神经肌肉标本上用电生理方法检测蛋白含量较高的Ⅹ_2、ⅩⅢ_2、ⅩⅣ_2及ⅩⅥ_1峰的作用,观察它们对微终板电位、终板电位及肌膜电位的影响。此外,还检测它们的离体去神经肌肉标本对乙酰胆碱敏感性的影响。实验结果提示,ⅩⅣ_2峰及ⅩⅥ_1峰中含有作用于突触后的神经毒性组分,ⅩⅢ_2峰中含有细胞毒性组分,X_2峰中含有细胞毒性及突触前神经毒性作用组分。再经Bio Rex-70柱层析后,从ⅩⅢ_2峰中纯化得一个细胞毒素,从ⅩⅣ_2峰中纯化得一个突触后神经毒素,它们在8M 尿素聚丙烯酰胺凝胶圆盘电泳中呈单一区带。凝胶过滤法测得该细胞毒索的分子量为13200、神经毒素的分子量为7,900。细胞毒素的小白鼠静脉注射最小致死量为4.1微克/克,神经毒素为0.16微克/克。

 
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