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纤维化     
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  fibrosis
     Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis
     干扰素-γ抗肝纤维化动物实验和临床研究
短句来源
     Laboratory Study on Acupuncture and Moxibustion in Preventing and Treating Rats' Immune Hepatic Fibrosis Induced by Porcine Serum
     针灸防治大鼠猪血清免疫性肝纤维化的实验研究
短句来源
     TGF-β/Smad Signaling Pathway and Renal Tubulointerstitial Fibrosis
     TGF-β/Smad信号通路在肾小管间质纤维化中的作用及机制的实验研究
短句来源
     Study on Differentially Expressed Genes in the Schistosoma Japonicum Infected Hepatic Fibrosis
     血吸虫病肝纤维化基因差异表达的研究
短句来源
     Studies on Molecular Pathogenetic Mechanism of Renal Fibrosis
     肾纤维化分子病理机制的研究
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  fibrotic
     UGT2B7 mRNA levels of 1, 2, 3 fibrotic grade patients were 156%, 208% and 192%, respectively.
     3级肝纤维化患者UGT2B7mRNA水平为0级肝纤维化的192%、1级的208%、2级的156%。
短句来源
     The therapeutic effect of IL-10 and effects of IL-10 on expression of TNF-α、IGF-1 and IGF-1R in fibrotic rat liver
     IL-10对大鼠肝纤维化的治疗作用及对TNF-α、IGF-1及IGF-1R表达的影响
短句来源
     Compared to 0 fibrotic grade group, UGT2B15 mRNA levels of 1, 2, 4 fibrotic grade patients were 172%, 208% and 243%, respectively.
     肝纤维化对UGT2B15RNA的表达有显著的影响,4级肝纤维化患者UGT2B15mRNA水平为0级肝纤维化的172%、1级的208%、2级的243%。
短句来源
     Results The relative mRNA expression of AT1R in fibrotic l iver tissues was significantly higher than that of normal liver tissues (1.27±0 .45 vs0.71±0.21, P<0.01).
     结果纤维化肝组织AT1RmRNA的相对表达量明显高于正常肝组织(1.27±0.45vs0.71±0.21,P<0.01)。
短句来源
     The restenosis rate was 16.67% in the fibrotic stage of endobronchial tuberculosis (EBTB), and was 60% in the inflammatory reaction stage of EBTB (χ2=4.564, P<0.05, but χ2c=2.437, P>0.05).
     纤维化期EBTB再狭窄率为16.67%,炎症反应期EBTB再狭窄率为60%(χ2=4.564,P<0.05,但χ2c=2.437,P>0.05)。
短句来源
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  fibrogenesis
     ROLES OF CYTOKINES TGF-β_1, PDGF-BB AND bFGF IN HUMAN LIVER FIBROGENESIS
     细胞因子TGF-β_1、PDGF-BB、bFGF在人肝纤维化中的作用
短句来源
     Results With the development of hepatic fibrogenesis,the protein expressions of RhoA and p-MLC(Thr18/Ser19) and the mRNA expression of RhoA were significantly increased.
     结果随着肝纤维化的进展,RhoA、p-MLC(Thr18/Ser19)蛋白表达明显增加,RhoAmRNA基因表达也逐渐加强。
短句来源
     Effect of cyclooxygenase-2 on liver fibrogenesis induced by CCl_4 in rats
     环氧合酶-2在CCl_4诱导大鼠肝纤维化形成中的作用
短句来源
     Relationship between different expressions of Smad3, Smad7 genes and liver fibrogenesis
     Smad3、Smad7基因表达与肝纤维化发病关系研究
短句来源
     Recently, many reports have shown that the fibrinolytic system, especially urokinasetype plasminogen activator (uPA) and its main inhibitor-plasminogen activator inhibitor-1 (PAI-1), was involved in the fibrogenesis of liver.
     目前研究表明,纤维蛋白溶解系统(又称纤溶系统),特别是尿激酶型纤溶酶原激活物(urokinasetype plasminogen activator,uPA)及其主要抑制物纤溶酶原激活物抑制剂-1(plasminogen activator inhibitor-1,PAI-1)与肝纤维化关系密切。
短句来源
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  fibrosis induced
     Expressions of IL-1_β and IL-1_βR of liver tissue in rats with hepatic fibrosis induced by CCl_4
     四氯化碳致肝纤维化大鼠肝组织中IL-1_β及IL-1_βR的表达
短句来源
     The study of No.2 of Earthworm's extractions (EE2) in the effects on the expressions of α-SMA,TGF-β1、MMP-13 and TIMP-1 of rat hepatic fibrosis induced by carbon tetrachioride
     地龙2号对大鼠肝纤维化α-SMA、TGF-β1、MMP-13及TIMP-1蛋白表达的影响
短句来源
     Effects of flavonoids extrated from Astragalus complanatus on liver fibrosis induced by CCl_4 and serum levels of IFN-γ and TGF-β_1 in rats
     沙苑子黄酮抗CCl_4大鼠肝纤维化作用及对IFN-γ,TGF-β_1的影响
短句来源
     Protection of Oral Keboli-2 Liquor(可博利2号口服液) Against Liver Fibrosis Induced by Carbon Tetrachloride in Rats
     可博利2号口服液对CCl_4诱导大鼠肝纤维化保护作用的实验研究
短句来源
     [Objective] To study the expression of Smad2/3, Smad7, TIMP-1 and TGF-β1 in hepatic fibrosis induced by the exposure of CCL4 and the effects of Losartan on them.
     目的探讨 CCL4 诱导的肝纤维化模型鼠肝组织 Smad2/3,Smad7,TIMP-1,TGF-β1 的表达及氯沙坦干预后对其表达的影响。
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  fibrosis
Hepatic steatosis, lobular inflammation, hepatocytic ballooning and fibrosis were presented widespread in NAFLD liver tissues.
      
Mild perisinusoidal fibrosis and periportal fibrosis were often observed in stage 1 cases.
      
According to the statistic analysis, hepatic steatosis was positively correlated with lobular inflammation, hepatocytic ballooning and fibrosis (r = 0.587, 0.488, 0.374, respectively, all P value >amp;lt; 0.01).
      
The number of microgranulomas, lipogranulomas and apoptotic bodies increased following severity of steatosis, lobular inflammation and fibrosis.
      
We suggest that the role of portal inflammation should be emphasized besides hepatic steatosis, lobular inflammation, hepatocyte ballooning and fibrosis in diagnosis and evaluation of NAFLD.
      
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  fibrotic
Fuzheng Huayu Decoction promotes protein synthesis and plays an anti-fibrotic role by anti-oxidation and accommodation of cell proliferation and transformation.
      
TGF-β1 treatment induced a fibrotic phenotype of RLE-6TN with increased expression of fibronectin (FN), α-smooth muscle actin (α-SMA) and vimentin, and decreased expression of E-cadherin (E-cad) and cytokeratin19 (CK19).
      
Although originally associated with tumorigenic processes, liver angiogenesis has also been observed in the context of different liver inflammatory, fibrotic, and ischemic conditions.
      
Histologically, an atypical infarct pattern was found, i.e., the common roundcell infiltration and the fibrotic process were surrounding but not penetrating the alcohol induced myocardial center of necrosis.
      
A prolonged treatment with daily oral doses of 1 mg/kg oxyfedrin during 30 days, did not alter the evolution of late isoproterenol-induced fibrotic heart lesions.
      
更多          
  fibrogenesis
The liver fibrogenesis was assessed using a digital image analysis instrument of Masson's trichrome stained sections.
      
It is associated with increased fibrogenesis and, in nongenotype 3 infection, with a reduced response to antiviral therapy.
      
Great progress has been made over the past 20 years in elucidating the mechanisms of hepatic fibrogenesis.
      
The recognition of the hepatic stellate cell as the fibrogenic cell of the liver, as well as the recognition of key cytokines involved in fibrogenesis, has facilitated the development of targeted antifibrotic therapies.
      
Great progress has been made over the past 20 years in elucidating the mechanisms of hepatic fibrogenesis.
      
更多          
  fibrosis induced
Objective: To explore the effect and mechanism of matrine (Mt.) on myocardial interstitial fibrosis induced by pressure overload.
      
Reactive oxygen species are known to act as biological mediators of tissue fibrosis induced by metallic compounds.
      
Thus, hypetension-induced fibrosis is probably triggered by other control mechanisms than fibrosis induced by MI.
      
Lung fibrosis induced by diquat after intratracheal administration
      
The aim of this study was to assess the antioxidant and antifibrotic effects of erdosteine on liver fibrosis induced by biliary obstruction in rats.
      
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