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纤维化
相关语句
  fibrosis
    Pharmacological Study on the Protective Action of Bicyclol Against Experimental Liver Injury and Fibrosis in Animals
    双环醇对实验性肝损伤、肝纤维化的保护作用和作用机制的研究
短句来源
    SIGNIFICANCE OF DETERMINATION OF SOME BIOCHEMICAL INDICES IN HEPATIC FIBROSIS OF ANIMAL SCHISTOSOMIASIS JAPONICA
    血吸虫病肝纤维化动物某些生化指标的检测及其意义
短句来源
    CHANGE IN LIVER COLLAGEN METABOLISM AND ITS SIGNIFICANCE DURING FIBROSIS FORMATION OF LIVER IN RABBITS WITH SCHISTOSOMIASIS
    兔血吸虫病肝纤维化形成过程中肝内胶原代谢的动态变化及其意义
短句来源
    ULTRASTRUCTURAL STUDIES ON EFFECTS OF COLCHICINE IN TREATING HEPATIC FIBROSIS OF SCHISTOSOMIASIS RABBITS
    秋水仙碱治疗家兔血吸虫病肝纤维化超微结构研究
短句来源
    Experimental Study of the Effect of IH764-3, a Potent Component Isolated from Salviae milltiorrhize, Against Pulmonary Fibrosis
    活血化瘀药物通脉灵及其有效单体IH764—3抗肺纤维化作用的实验研究
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  “纤维化”译为未确定词的双语例句
    An Experimental Research of Antifibrotic Effect of α-Tocopheral and Tetrandrine in Rat Liver
    维生素E和汉防己甲素防治肝纤维化的实验研究
短句来源
    [Methods] A total of 40 healthy Wistar rats were divided into four groups randomly: control group, model group, prevention group and treatment group.
    方法 Wistar大鼠 40 只,随机分成正常对照组、模型组、氯沙坦预防组和治疗组,采用 CCL4 皮下注射构建肝纤维化模型。 行 HE 和 VG 染色,判断肝组织炎症和纤维化的程度。
短句来源
    In imatinib mesylate and dexamethasone groups alveolitis grades and PF induced by bleomycin were obviously alleviated. The concentration of HYP and expression of PDGF-BB in lung tissues decreased in imatinib mesylate and dexamethasone groups compared with those in model group (P<0.05 or P<0.01).
    与模型组比较,格列卫组与地塞米松组的肺泡炎分级和肺纤维化程度均明显减轻,HYP含量和肺组织PDGF-BB表达均降低(P<0.05或P<0.01);
短句来源
    Effects of vitamin E on carbon tetrachloride-induced hepatic fibrosis-An experimental study
    维生素E抗大鼠四氯化碳所致肝纤维化的实验研究
短句来源
    Primary Study of Gamma-Interferon on Anti-Hepatofibrosis in Rats
    γ-干扰素抗大鼠肝纤维化的初步研究
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  fibrosis
Hepatic steatosis, lobular inflammation, hepatocytic ballooning and fibrosis were presented widespread in NAFLD liver tissues.
      
Mild perisinusoidal fibrosis and periportal fibrosis were often observed in stage 1 cases.
      
According to the statistic analysis, hepatic steatosis was positively correlated with lobular inflammation, hepatocytic ballooning and fibrosis (r = 0.587, 0.488, 0.374, respectively, all P value >amp;lt; 0.01).
      
The number of microgranulomas, lipogranulomas and apoptotic bodies increased following severity of steatosis, lobular inflammation and fibrosis.
      
We suggest that the role of portal inflammation should be emphasized besides hepatic steatosis, lobular inflammation, hepatocyte ballooning and fibrosis in diagnosis and evaluation of NAFLD.
      
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The distribution of various ~(57)Go-labelled Zhengguangmycin preparations, namely: single natural components A_2, A_4, A_5, A_6, B_2, a mixed preparation comprising of components A_2+B_2, and a single component derivation A_(5033) was studied in mice bearing solid type Ehrlich carcinoma. It was found that all these preparations exhibited antitumor and tumortropic properties. Among all the preparations, components A_5 and A_6 exhibited the strongest tumor-tropic property.Given at equivalent toxicity dosage (1/20...

The distribution of various ~(57)Go-labelled Zhengguangmycin preparations, namely: single natural components A_2, A_4, A_5, A_6, B_2, a mixed preparation comprising of components A_2+B_2, and a single component derivation A_(5033) was studied in mice bearing solid type Ehrlich carcinoma. It was found that all these preparations exhibited antitumor and tumortropic properties. Among all the preparations, components A_5 and A_6 exhibited the strongest tumor-tropic property.Given at equivalent toxicity dosage (1/20 LD_(50), components A_5 and A_4 exhibited the highest rate of tumor inhibition. The uptake of radioactivity in the mouse liver, kidney and tumor was the highest with component A_6 and the lowest with preparation A_(5033). It appears that A_6 would be the least promising component for clinical trial. The preparation A_(5033), beside the above mentioned properties, has the additional advantage of having a low uptake in the lung, rapid excretion through the kidney and the lowest acute toxicity. Moreover, A_(5033) exhibited a satisfactory tumor inhibition rate as compared with other prepations when given at equivalent toxicity dosage. It therefore appears to be worthy of further investigation from the point of diminishing pulmonary fibrosis. Though the uptake of component As in the mouse kidney and liver was rather high, yet it was lower than that of A_6. It was excreted slowly through the urine. On the ground that As has the strongest tumor inhibitory activity and a better retention in the animal body, it would also appear to be a component worthy of further study as an antitumor agent.

~(57)Co标记的七种争光霉素组分(A_2+B_2混合品、A_2、A_4、A_5、A_6、A_(5033)和B_2)在实体型艾氏腹水癌小鼠的分布实验中,发现七种组分都亲瘤和抑瘤。争光霉素A_5和A_6的亲瘤性最高。用等毒性剂量,A_5、A_4和A_2具有最高的抑瘤性。小鼠肝、肾和肿瘤对各种标记的争光霉素组分的摄取以A_(5033)为最低,A_6为最高,因此目前看来,以A_6进行临床试用的前景似比其他的组分为差。A_(5033)在肺中集聚少,排出较快,急性毒性又最低,按相等的LD_(50)剂量给药其抑瘤率也较高,从减少肺纤维化这点考虑,它可能是值得进一步研究的。A_5亲瘤抑瘤较高,肾和肝摄取较高,但较A_6为低,排出较慢,在体内保留时间较长,也是一种有发展前途的单一争光霉素组分。

In order to study the pathogenesis of hepatic fibrosis, serum monoamine oxidase, mucoprotein, plasma proline and hydroxyproline were determined on 7 rabbits infected with Schistosoma japonicum. After infection serum monoamine oxidase and mucoprotein increased markedly, while plasm hydroxyproline and proline decreased evidently. After pyquiton treatment serum mucoprotein rapidly decreased and returned to normal level; whereas serum monoamine oxidase also diminished significantly, but didn't return to normal....

In order to study the pathogenesis of hepatic fibrosis, serum monoamine oxidase, mucoprotein, plasma proline and hydroxyproline were determined on 7 rabbits infected with Schistosoma japonicum. After infection serum monoamine oxidase and mucoprotein increased markedly, while plasm hydroxyproline and proline decreased evidently. After pyquiton treatment serum mucoprotein rapidly decreased and returned to normal level; whereas serum monoamine oxidase also diminished significantly, but didn't return to normal. It is suggested these biochemical indices might be of value in the early diagnosis of hepatic fibrosis and the evaluation of the effectiveness of therapy in schistosomiasis.

观察了血吸虫病家兔感染前后、形成肝纤维化前后和吡喹酮灌胃给药前后的血清单胺氧化酶、粘蛋白、血浆游离脯氨酸和羟脯氨酸的动态变化。感染后血清单胺氧化酶和粘蛋白明显升高,血浆游离羟脯氨酸和脯氨酸显著降低。治疗后血清粘蛋白迅速显著降低,并回复到正常水平;血清单胺氧化酶也显著降低,但未恢复正常。这些生化指标在肝纤维化的早期诊断和疗效考核方面有一定参考价值。

Lung fibrosis Was produced by single intratracheal injection of bleomycin A5 ( 5 mg/kg) . The effect of sodium fulvate and anisodamine on that model were observed. The results showed that sodium fulvate (50mg/kg) and anisodamine ( 4 mg/kg) had significant protective effect on lung fibrosis induced by bleomycinA5. Lung index and hydroxyproline content of lung were decreased significantly. Histological examination showed that the pathological changes in lung were diminished as well. It is suggested that inhibition...

Lung fibrosis Was produced by single intratracheal injection of bleomycin A5 ( 5 mg/kg) . The effect of sodium fulvate and anisodamine on that model were observed. The results showed that sodium fulvate (50mg/kg) and anisodamine ( 4 mg/kg) had significant protective effect on lung fibrosis induced by bleomycinA5. Lung index and hydroxyproline content of lung were decreased significantly. Histological examination showed that the pathological changes in lung were diminished as well. It is suggested that inhibition of inflammatory reaction might be a possible mechanism for protective effect of sodium fulvate and anisodamine.

以平阳霉素(Bleomycin As,5mg/kg)气管内一次滴入形成大、小白鼠肺纤维化模型。观察了黄腐酸钠和山莨菪碱对该模型的作用。结果表明,黄腐酸钠(50mg/kg)和山菪莨碱(4mg/kg)均可明显减轻肺纤维化:使肺系数减小,肺羟脯氨酸含量降低,组织学检查也表明肺病变明显减轻。黄腐酸钠和山莨菪碱对肺纤维化的保护作用可能与抑制炎症有关。

 
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