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   喉鳞癌的 的翻译结果: 查询用时:0.583秒
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喉鳞癌的
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  laryngeal squamous cell carcinoma
     Objective To evaluate the role of human papillomavirus type 16,18(HPV 16,18) infection and ras activation in laryngeal squamous cell carcinoma and to investigate the association between HPV and ras gene mutations.
     1目的 探讨人乳头瘤病毒 16 ,18型 (HPV16 ,18)感染及 ras基因突变与喉鳞癌的关系。
短句来源
     Objective:To evaluate the role of p53 gene mutations and human papillomavirus type 16,18(HPV16,18) infection in laryngeal squamous cell carcinoma and to investigate the association between HPV infection and p53 gene mutations.
     目的 :探讨抑癌基因p53突变和人类乳头状瘤病毒 16,18型 (HPV16,18)感染与喉鳞癌的关系及二者在喉鳞癌中的相关性。
短句来源
     p53 GENE MUTATION AND ras GENE MUTATION AND HPV IN LARYNGEAL SQUAMOUS CELL CARCINOMA
     p53和ras基因突变及HPV感染与喉鳞癌的关系
短句来源
     Conclusion: Overexpression of HPV16E7 protein and loss of Rb protein expression may contribute to the genesis of human laryngeal squamous cell carcinoma.
     结论:HPV16E7蛋白的表达升高和Rb蛋白的表达下降可能会导致人喉鳞癌的发生和发展;
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     Objective:To study the correlation between the expression of CD44s,CD44v6 and the clinicopathological characters of laryngeal squamous cell carcinoma (LSCC) so as to analyze the role of them in occurrence and progression of LSCC.
     目的 :探讨标准型 CD44(CD44s)及变异型 CD44(CD44v6)在喉鳞癌的表达与临床病理特征的关系 ,及其在喉鳞癌发生发展中的作用。
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  larynx squamous carcinoma
     Clinical relationship study of bcl-2 and p53 protein with larynx squamous carcinoma
     bcl-2、p53蛋白与喉鳞癌的临床相关性研究
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     Objective It is to study the expression of bcl-2 and p53 protein in larynx squamous carcinoma and the interrelationship of them with patho-class and clinical stage of larynx squamous carcinoma and patient survival rate.
     目的探讨bcl-2及p53蛋白在喉鳞癌患者中的表达及与喉鳞癌的病理分级、临床分期和患者生存率间的相互关系。
短句来源
     Conclusion The expressions of bcl-2 and p53 protein have a relationship with patho-class,clinical stage and cervical lymph node metastasis of larynx squamous carcinoma and 3 a,5 a survival rates of the patients. It can be used as an evaluated index for aggravation,metastasis and prognosis of larynx squamous carcinoma.
     结论bcl-2、p53蛋白表达与喉鳞癌的病理分级、临床分期、颈淋巴结转移和患者的3,5 a生存率有一定关系,可作为评定喉鳞癌的进展、预测其转移与预后的指标。
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  “喉鳞癌的”译为未确定词的双语例句
     The presence of human papillomavirus (HPV) genomes 6B/11 and 16/18 DNA was examined in 32 cases of laryngeal carcinomas with in situ hybridization (ISH),which had been fixed in formalin and embedded in paraffin.
     为了证实人乳头瘤病毒(HPV)亚型的感染与喉鳞癌的关系,采用原位杂交技术,荧光素标记HPV6B/11、16、18DNA为探针,分别对32例福尔马林固定、石蜡包埋的喉鳞癌进行HPV6B/11、16、18型检测。
短句来源
     Conclusion: Inactivation of the p53 pathway and overexpression of HPV16/18-E6 and MDM2 may contribute to the genesis of human laryngeal cell carcinoma.
     结论HPV16/18-E6、MDM2蛋白的过表达和p53的失活与人喉鳞癌的发生发展密切相关。
短句来源
     The positive expression rate of P 73 in LSCC tissues and polyp of vocal cord tissues were 66.7%(20/30 )and 50%(15/30)respectively(P>0.05). P 73 was not correlated with the clinical stages and clinical typ ing of LSCC.
     P73阳性表达率在喉癌组织和声带息肉中分别为:66.7%(20/30),50.0%(15/30)(P>0.05),P73与喉鳞癌的临床分型、分期无相关性。
短句来源
     Results ①Laryngeal carcinomas with cervical lymph node metastasis had a significantly higher microvessel density than those without metastasis ( 32.1518 ± 6.489 , 18.0672 ± 4.983 , P< 0.01 );
     结果 ①颈淋巴结转移组喉鳞癌的微血管密度显著高于非转移组 (32 .1518± 6 .4 89∶18.0 6 72± 4 .983,P <0 .0 1) ;
短句来源
     The positive expression rates of P73 in LSCC tissues, polyps of the vocal cord tissues, paracancerous tissues, and nontypical hyperplasis tissues were 53.06% (26/49), 36.84% (7/19), 41.67% (5/12) and 37.5% (3/8) respectively(P> 0.05 ). The gene P73 was not correlated with the clinical stages and clinical typing of LSCC.
     P73阳性表达率在喉鳞癌组织、声带息肉、癌旁组织及非典型增生组织中分别为 5 3.0 6 % (2 6 / 4 9) ,36 .84 % (7/ 19) ,4 1.6 7% (5 / 12 ) ,37.5 % (3/ 8) ,P73与喉鳞癌的临床分型、分期无相关性。
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  laryngeal squamous cell carcinoma
It may serve as an alternative mechanism of activating the pathogenesis of human laryngeal squamous cell carcinoma.
      
A correlative study of Ki67 and vascular endothelial growth factor and their value in laryngeal squamous cell carcinoma
      
Objective: To study the correlation between Ki67 and vascular endothelial growth factor(VEGF) and the significance of their expression in laryngeal squamous cell carcinoma(LSCC).
      
Prognostic value of Ki67 and VEGF expression in laryngeal squamous cell carcinoma
      
OBJECTIVE To investigate the prognostic value of measuring Ki67 and VEGF expression in laryngeal squamous cell carcinoma (LSCC).
      
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  larynx squamous carcinoma
Among them, the radioresistant cell line Hep-2R was isolated and established from a radiosensitive human larynx squamous carcinoma cell line Hep-2 by our center.
      


55 cases of laryngeal cancer were treated with surgery alone from 1977 to 1981 in our hospital. The operative techniques employed included the Arslan's method (31 cases) and Vega's method (24 cases). All the cases were followed up for 3-7 years. The results showed that 5-year survival rate was achieved in 78% of the cases of supraglottic cancer and in 77% of the cases of glottic cancer.

1977~1981年采用Arslan及Vega术治疗喉鳞癌55例。随访3~7年,声门上区癌术后5年的生存率达74.7%,声门癌达75.5%。

DNA ploidy, S% and proli-ferative index(PI)of carcinomatous cell wereevaluated with FCM in 41 patients withlaryngeal primary squamous cell carcinomaswhich were operated on in our departmentduring the period between Jan.1979 to Oct.1987.The results showed that DNA aneup-loidy was identified in 65.85% of the case,(27/41) and patients with aneuploid carci-nomas had higher S% (mean±standard:23.22±9.57%), higher PI (mean±standard: 37.59±9.57%)and higher rate of relapse and/ormetastasis than those with diploid tumous(55.55%...

DNA ploidy, S% and proli-ferative index(PI)of carcinomatous cell wereevaluated with FCM in 41 patients withlaryngeal primary squamous cell carcinomaswhich were operated on in our departmentduring the period between Jan.1979 to Oct.1987.The results showed that DNA aneup-loidy was identified in 65.85% of the case,(27/41) and patients with aneuploid carci-nomas had higher S% (mean±standard:23.22±9.57%), higher PI (mean±standard: 37.59±9.57%)and higher rate of relapse and/ormetastasis than those with diploid tumous(55.55% vs 11.77%, P<0.025). Patientswith aneuploid carcinomas also correlatedwith an unfavorable prognosis comperedwith those with diploid tumors.Cases withaneuploid and dipliod carcinomas had 66.11%and 92.86% respectively for two years posto-peration survival rate; 46.74% and 92.86% res-pectively for five years postoperation sur-vival rate(Logrank test:X~2=5. 96, P<0.025).We conclude that nuclear DNA measure-ment with flow cytometry is of important-si gnificance in estimating prognosis andguiding treatment for laryngeal squamouscell carcinomas.

作者对41例行手术治疗并随访2年以上的喉鳞癌患者用流式细胞测定法测定癌细胞核DNA量。结果:异倍体率为65.85%。异倍体肿瘤细胞的S%,分裂增殖指数和肿瘤患者的复发和(或)转移率显著高于二倍体肿瘤者(P<0.025);患者的生存率显著低于二倍体肿瘤者(P<0.025)。表明:肿瘤细胞核DNA测定能提供重要的预后信息,有助于改进治疗,提高患者生存率。

The testosterone, progestrone and estradiol receptors (TR, PR, ER) were analyzed with direct fluorescent histochemistry in 33 laryngeal squamous cell carcinomas and their neighbering tissues. In the laryngeal tissues, the manifestation of these receptors was richer in columnar epithelia than in squamous epithelia, and stronger in ductal epithelia than in acinar epithelia. In 33 laryngeal carcinomas, the positive indication rates were 65% in TR, 43% in PR and 21% in ER, Fespectively. These percentages indicated...

The testosterone, progestrone and estradiol receptors (TR, PR, ER) were analyzed with direct fluorescent histochemistry in 33 laryngeal squamous cell carcinomas and their neighbering tissues. In the laryngeal tissues, the manifestation of these receptors was richer in columnar epithelia than in squamous epithelia, and stronger in ductal epithelia than in acinar epithelia. In 33 laryngeal carcinomas, the positive indication rates were 65% in TR, 43% in PR and 21% in ER, Fespectively. These percentages indicated that the laryngeal carcinomas were more dependent on testosterone than on progesterone and estradiol. These three receptors were corresponded to each other in 48% of the cases, while in the remaining 52%, these three receptors were uncoordinated. In one of the 33 cases, the manifestation of the receptors of the metastatic carcinoma in lymph nodes was different from the primary carcinoma. From the point of view of receptors these phenomena showed the heterogeneity of the cancer cells existed in some laryngeal carcinomas. The intensities of the manifestation of the receptors were related to the tissues differentiation; such as: richer receptors in benign squamous epithelia as opposed to malignancy, and richer receptors in well differeutiated squamous cell carcinomas as opposed to poorly differentiated squamous cell carcinomas.

用荧光组化法测定33例喉鳞癌及癌旁组织的睾丸酮、孕酮和雌二醇受体。3个受体在癌旁的表达为表面柱状上皮强于鳞状上皮,腺管上皮强于腺泡。在33例喉鳞癌中3个受体的阳性检出率分别为65%、43%和21%;显示喉鳞癌更依赖于睾丸酮。有48%的病例3个受体在同一病例表达一致,52%不一致;另1例伴淋巴结转移癌,其受体表达也与原发癌不一致;从受体角度显示部分病例癌细胞具异质性。受体的表达强度与组织分化有关,在良性鳞状上皮强于恶性,在高分化癌强于低分化癌。

 
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