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结肠腺癌     
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  colon adenocarcinoma
     Study on Expression and Significance of JSB1 and C219 Protein in Colon Adenocarcinoma
     JSB1和C219蛋白在结肠腺癌的表达及其意义
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     Antisense inhibition effect of ~(99) Tc~m-VIP-ASON on the human colon adenocarcinoma cell line HT29
     ~(99)Tc~m-VIP-ASON对结肠腺癌HT29细胞的反义抑制研究
短句来源
     Retrovirus-mediated RNA inhibition of EphA2 gene expression in colon adenocarcinoma HCT-8 cells
     RNA干扰抑制EphA2癌基因在结肠腺癌HCT-8细胞系中的表达
短句来源
     Expression and Significance of Transforming Growth Factor β_1 in Colon Adenocarcinoma
     转化生长因子-β_1在结肠腺癌中的表达意义
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     Methods TGF-β1 in colon adenocarcinoma of 30 cases and normal colonitis tissue of 30 cases were examined using S-P immunohistochemical staining.
     方法采用S-P免疫组织化学染色方法,对30例结肠腺癌,30例正常结肠组织中的TGF-β1进行检测。
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  colonic adenocarcinoma
     An Oral DNA Vaccine pcDNA3.1+/flk-1_(n1-7) Against Colonic Adenocarcinoma of Mouse
     口服DNA疫苗pcDNA3.1+/flk-1_(n1-7)在抗小鼠结肠腺癌中的实验研究
短句来源
     Methods The expression of MAGE-4 gene in 44 human colonic adenocarcinoma tissue specimens and 15 normal colon tissue specimens were tested by RT-PCR.
     方法采用RT-PCR方法检测44份结肠腺癌组织及15份癌旁正常组织标本中MAGE-4基因的表达。
短句来源
     Objective To test the expression of melanoma antigen-4(MAGE-4) gene in human colonic adenocarcinoma tissue.
     目的检测黑色素瘤抗原-4(MAGE-4)基因在结肠腺癌中的表达情况。
短句来源
     Conclusion Specific expression of MAGE-4 gene was proved in human colonic adenocarcinoma tissue,which indicated that MAGE-4 gene might be used for the development of colonic carcinoma vaccine.
     结论MAGE-4基因在结肠腺癌组织中呈特异性表达,提示该基因可用于结肠癌疫苗的开发。
短句来源
     Results The positive rate of MAGE-4 was 38.64% in 44 human colonic adenocarcinoma tissue specimens. However,no expression of MAGE-4 gene was detected in 15 normal colon tissue specimens.
     结果44份结肠腺癌标本中,MAGE-4基因的阳性表达率为38.64%,而在15份癌旁正常组织中均不表达,两组比较差异有显著意义。
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  adenocarcinoma of colon
     Methods:immunohistochemistry(streptomycin avidin-biotinperoxidase complex,SP)was adopted to detect the expression of MMP-9VEGF,collagen IV and FVIII Ag in adenocarcinoma of colon.
     方法:采用免疫组织化学SP法检测结肠腺癌MMP-9、VEGF、Ⅳ型胶原及FⅧAg的表达情况。
短句来源
     Results 35 cases were totaled covering adenocarcinoma of lung, squamous carcinoma of oral cavity, adenocarcinoma of colon, mammary carcinoma and glioma.
     结果 共测试了临床肿瘤标本35例,包括肺腺癌、口腔鳞癌、结肠腺癌、乳腺癌和脑星形细胞瘤等。
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     Methods Nine patients with large LNML 7-21 cm in diameter (mean diameter 15 cm), had already resected the primary lesions, one from malignant mesenchymoma of stomach, four from adenocarcinoma of colon, three from carcinoma of rectum and one from lung cancer.
     方法9例LNML患者,瘤体直径7~21cm,平均15cm,全部患者均已行原发病灶切除。 原发病包括胃间质恶性肿瘤1例,结肠腺癌4例,直肠癌3例,肺癌1例。
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  colorectal adenocarcinoma
     The expression of CD44v6 in the high and middle differentiated colorectal cancer were 45.8% (11/24) and 68.7% (11/16) respectively, which had significant difference (P<0.05), but which had no striking difference from the expression in human colorectal adenocarcinoma (P>0.05).
     在高、中分化腺癌组织中 ,CD44 v6阳性率分别为 45 .8%(11/ 2 4)和 6 8.7%(11/ 16 ) ,有显著性差异(P<0 .0 5 ) ,但在直肠腺癌组织与结肠腺癌组织间表达无显著性差别 (P>0 .0 5 ) .
短句来源
     But the frequency of slow acetylator genotype was increased significantly in patients with colorectal adenocarcinoma compared with controls (42.8% vs 33.7%,P=0.033,OR=1.576,95%CI:1.037—2.396).
     但与正常对照组相比,结肠腺癌患者中慢型乙酰化基因型频率增高(42.8%比33.7%,P= 0.033,OR=1.576,95%CI:1.037~2.396)。
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     Objective To analyze the association of genetic polymorphism of Glutathione S transferase (GST) M1, T1 and N acetyltransferase 1(NAT1) with genetic susceptibility to sporadic colorectal adenocarcinoma (SCRAC).
     目的 探讨谷胱甘肽S 转移酶 (GST)M 1、T1和N 乙酰化转移酶 1(NAT1)基因多态与散发性结肠腺癌 (SCRAC)遗传易感性的关联。
短句来源
     The in vitro and in vivo chemotactic effect on immune cells by hMIP-1β gene transfected murine colorectal adenocarcinoma CT26 cells
     hMIP-1β基因转染小鼠结肠腺癌CT26细胞对免疫细胞的体内外趋化作用
短句来源
     The expression of p27~(kip1) in colorectal adenocarcinoma and the correlation with the clinicopathological features
     结肠腺癌组织p27~(kip1)表达水平及与临床病理因素的关系
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  colon adenocarcinoma
Modality of Cell Death Induced by Foscan?-Based Photodynamic Treatment in Human Colon Adenocarcinoma Cell Line HT29
      
Organoid Culture of Human Colon Adenocarcinoma as a Model of Local Intercellular Interactions
      
Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds
      
Changes of nuclear matrix protein and its relationship with c-erbB-2 in human colon adenocarcinoma
      
Colorectal cancer results from the accumulation of genetic and epigenetic alterations that transform colonic epithelial cells into colon adenocarcinoma cells.
      
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  colonic adenocarcinoma
Insulin-like growth factor binding-protein-7 (IGFBP7) was obtained from our previous colonic adenocarcinoma (CRC) and normal mucosa suppression subtraction hybridization (SSH) cDNA libraries.
      
At pathology, the neoplastic mass was identified as malakoplakia with a small area corresponding to a moderately differentiated colonic adenocarcinoma.
      
Primary minute invasive de novo colonic adenocarcinoma appearing as submucosal tumor
      
infusion) to WAG rats bearing hind limb solid colonic adenocarcinoma implants.
      
Imaging features of ovarian metastases from colonic adenocarcinoma in adolescents
      
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  adenocarcinoma of colon
Unusual appearance of brain metastasis from adenocarcinoma of colon
      
Histological characteristics of AC3488UM tumor were poorly differentiated adenocarcinoma of colon.
      
Only one malignant liver tumor, which had metastasized from a mucinous adenocarcinoma of colon, showed ADC of greater than 1.6x 1O mm2/sec.
      
Preoperative histologic grading can not be used as a factor in deciding the length of the margin of resection in adenocarcinoma of colon and rectum.
      
  colorectal adenocarcinoma
Deletions of the YNZ22and Alu-VpA/MycL1Loci and Post-Surgery Prognosis in Human Colorectal Adenocarcinoma
      
HIF-1 α a transcripts were positive in 67.7% (42/62) and 44.4% (8/18) of colorectal adenocarcinoma and adenoma, respectively.
      
The positive staining rate of NDRG1 protein was significant higher in colorectal adenocarcinoma group than that in colorectal adenoma group (p >amp;lt; 0.05).
      
Correlationship between cellular DNA and AgNOR protein content in the developing course of colorectal adenocarcinoma
      
Future approaches to improve sensitivity of fecal DNA detection of colorectal adenocarcinoma may require the inclusion of epigenetic biomarkers, the use of colonocytes isolated from feces, or both.
      
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  其他


A clinicopathological study on 273 cases of colonic cancer was done.The right sidedcolonic cancer differed from the left sided ones in their age distribution,clinical symptomsand signs,histopathological patterns,metastatic rate of lymph nodes,what so ever.Causesin creating these differences were discussed.

本文将273例手术切除的结肠腺癌分左右两侧进行比较,发现右侧结肠癌年龄构成明显高于左侧,临床以腹痛、腹块最常见,贫血,消瘦,腹水等消耗性症状也明显多于左侧;组织学类型中粘液腺癌发生率高,淋巴结转移率亦高于左侧。对发生上述差异的原因进行了分析。

Selective superior and inferior mesenteric arteriographies were performed in 18 patients with gastrointestinal bleeding.Twelve cases of lower gastrointesti- nal hemorrhage were diagnosed by their angiograms.They consist of two cases of leiomyoma in the small bowel,two cases of angiodysplasia in the small bowel,two cases of nonocclusive mesenteric infarction,two cases of malignant lymphoma,three cases of colonic adenocarcinoma and one case of colonic polyp. Three typical cases were reported.The authors emphasized...

Selective superior and inferior mesenteric arteriographies were performed in 18 patients with gastrointestinal bleeding.Twelve cases of lower gastrointesti- nal hemorrhage were diagnosed by their angiograms.They consist of two cases of leiomyoma in the small bowel,two cases of angiodysplasia in the small bowel,two cases of nonocclusive mesenteric infarction,two cases of malignant lymphoma,three cases of colonic adenocarcinoma and one case of colonic polyp. Three typical cases were reported.The authors emphasized the value of the mesenteric arteriography in lower gastrointestinal bleeding.The X-ray signs of relating intestinal diseases were discussed.And the opinion how to improve the diagnostic sensitivity was proposed.

对18例疑为下消化道出血的患者作选择性肠系膜动脉造影,发现小肠平滑肌瘤2例、小肠血管发育异常2例、非闭塞性肠系膜血管梗塞症2例、回盲部和升结肠恶性淋巴瘤各1例、结肠腺癌3例以及乙状结肠息肉1例。本文对其中3例典型病例作了介绍,还对选择性肠系膜动脉造影诊断下消化道出血的价值、造影片上各类出血性病变的鉴别诊断及如何提高阳性诊断率等问题进行了讨论。

The expression of monoclonal antibody MC3 and its relationship to abno-ormal mucin secretion were investigated in colon tumors, including polypoid adenomas (32 cases ), villous adenomas (11), adenomas with atypical hyperplasia(18) and adenocarcino-mas(36), with PAP immunohistochemistry and aldehyde fuscin-alcian blue histochemical methods. The results showed that MC3, which mainly appeared in adenocarcinoma of colon, expressed luminal .marginal and cellular types in adenoepithelium. The former two types could...

The expression of monoclonal antibody MC3 and its relationship to abno-ormal mucin secretion were investigated in colon tumors, including polypoid adenomas (32 cases ), villous adenomas (11), adenomas with atypical hyperplasia(18) and adenocarcino-mas(36), with PAP immunohistochemistry and aldehyde fuscin-alcian blue histochemical methods. The results showed that MC3, which mainly appeared in adenocarcinoma of colon, expressed luminal .marginal and cellular types in adenoepithelium. The former two types could be seen also in adenoma of colon, but different positive staining of MC3 was exised. Some connection between expression of MC3 and adnormal mucin secretion of colon could be observed too. It is suggested that the appearance of MC3 may be related to this secretion of mucin.

本文应用抗人结肠癌单克隆抗体MC_3对32例结肠腺病性息肉。11例绒毛状腺病,18例结肠腺瘤伴不典型增生和36例结肠腺癌组织进行了PAP免疫组织化学染色,并同时采用醛复红—阿辛蓝(AF/AB)复合染色法,观察了结肠癌异型粘液分泌与MC_3表达的关系。结果表明,MC_3主要为结肠肿瘤的标记癌组织MC_3表达有三种类型即腺腔型腔缘型和细胞型、前两型表达亦见于结肠腺瘤,其中腺瘸性息肉和绒毛状腺瘤MC_3表达的阳性率存在差异。本文还观察到癌组织MC_3表达的类型与强度癌细胞分泌非硫酸粘液有一定关系。 本文提示MC_3与结肠肿瘤细胞的分泌有关,并可将其用于结肠癌细胞生物学特性研究及结肠肿瘤的辅助诊断。

 
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