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胞浆内游离钙
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  cytoplasmic free calcium
     Effect of J-894 on Cytoplasmic Free Calcium Concentration in Human Platelet Activation
     J-894对人体血小板激活时胞浆内游离钙浓度的影响
短句来源
     The intracellular free calcium concentration plays a key role as the second messenger in the regulation of cellular reaction. The changes of cytoplasmic free calcium concentration([Ca~(2+)]_i) in human platelets loaded with the fluorescent calcium indicator quin-2 were measured in this study.
     细胞内游离钙浓度在细胞反应的调节中作为第二信使起很重要的作用,本实验采用荧光钙指示剂 quin-2测定血小板胞浆内游离钙浓度[Ca~(2+)]_i 的变化。
短句来源
     TFA significantly reduced the resting and CaCl2-induced increase of cytoplasmic free calcium concentration ([Ca2+]i) in rabbits platelet in vitro, and the effects were in concentration-dependent manner.
     TFA(0.025,0.050,0.100mg·ml~(-1))对胶原诱导的血小板聚集可产生浓度依赖性的抑制作用,TFA可明显降低静息状态下血小板胞浆内游离钙浓度和抑制CaCl_2诱导的血小板胞浆内游离钙浓度的升高。
短句来源
     MAIN OUTCOME MEASURES ① Changes of neuronal cytoplasmic free calcium concentration.
     主要观察指标:①神经元胞浆内游离钙浓度变化。
短句来源
     PTI fluorescence imaging system was used to detect the changes of neuronal cytoplasmic free calcium concentration meanwhile Western blot technique was used to determine the changes of neuronal P-CREB content.
     用PTI荧光成像系统测量神经元胞浆内游离钙浓度变化,用Westernblot方法测定神经元内P-CREB的含量变化。
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  “胞浆内游离钙”译为未确定词的双语例句
     ( 2 ) plasma concentration of 5-HT, 5-HT_2 receptor specific binding and platelet intracellular free calcium concentration;
     (2)血浆5-HT水平、5-HT_2受体特异结合及血小板胞浆内游离钙(〖Ca~(2+)〗_i);
短句来源
     fluorescent dye Fluo 3/AM and Fura 2/AM were used to test the change in intracellular free calcium;
     以Fluo 3/AM和Fura 2 /AM为探针检测胞浆内游离钙离子浓度 ([Ca2 +]i)的变化 ;
短句来源
     CP-154526 could remarkably suppress the CRH (10-6 mol/L)induced increase in cytoplasmic free Ca2+ concentration and cAMP content in hypothalamic neurons Ca2+ concentration :(240±22),(171±16)nmol/L;
     CP-154526可明显抑制促肾上腺皮质激素释放激素(10-6mol/L)刺激的下丘脑神经元胞浆内游离钙浓度和环磷酸腺苷含量的生成[钙离子浓度:(240±22),(171±16)nmol/L;环磷酸腺苷含量:(3.26±0.19),(2.33±0.21)pmol/dish,P<0.01]。
短句来源
     When the calcium release channel open, calcium is put into the cytoplasm from SR.
     当肌浆网上钙释放通道(calcium release channel)被激活开放时,Ca~(2+)便从SR进入胞浆,当胞浆内游离钙达10~(-5)M时肌钙蛋白被激活。
短句来源
     RESULTS: The cytoplasmic free Ca2+ concentration and cAMP content were relatively lower in the hypothalamic neurons in normal control group,which obviously increased due to CRH stimulation (240±22),(153±11)nmol/L; (3.26±0.19),(0.44±0.02) pmol/dish,P < 0.01 ;
     结果:正常对照组的下丘脑神经元胞浆内游离钙浓度和环磷酸腺苷含量较低,外源性促肾上腺皮质激素释放激素刺激后,胞浆内游离钙浓度立即升高,神经元胞浆内环磷酸腺苷生成明显增加[(240±22),(153±11)nmol/L;(3.26±0.19),(0.44±0.02)pmol/dish,P<0.01];
短句来源
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  相似匹配句对
     MAIN OUTCOME MEASURES: ①Cytoplasmic free Ca2+ concentration in hypothalamic neurons.
     主要观察指标:①下丘脑神经元胞浆游离浓度。
短句来源
     MAIN OUTCOME MEASURES ① Changes of neuronal cytoplasmic free calcium concentration.
     主要观察指标:①神经元胞浆游离浓度变化。
短句来源
     The effect of estrogen on intracellular calcium concentration in human spermatozoa
     雌激素对人精子胞浆游离离子浓度的影响
短句来源
     Effect of J-894 on Cytoplasmic Free Calcium Concentration in Human Platelet Activation
     J-894对人体血小板激活时胞浆游离浓度的影响
短句来源
     Effect of berberine on the cytosolic calcium concentration in the single ventricular cell of guinea pig
     小檗碱对豚鼠心室肌细胞胞浆游离离子浓度的影响
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  cytoplasmic free calcium
Effect of interleukin-1β on the elevation of cytoplasmic free calcium of the cultured hippocampal neurons induced by L-glutamate
      
Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose
      
This strongly suggests that there is no correlation between maximal stimulation of cytoplasmic free calcium, and maximal stimulation of migration.
      
The mobilization of cytoplasmic free calcium is also normal.
      
Cytoplasmic free calcium has been observed in fura 2-loaded stria vascularis of the guinea pig.
      
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Hernandezine, an isoquinoline alkaloid, is one of the active ingredients isolated from Thalictrum glandulosissimum. It was found to inhibit markedly rat platelet aggregation induced by collagen, ADP, calicimycin (A-23187) and arachidonic acid (AA) in vitro. The IC50 were 14.5, 41.6, 44.1 and 48.3μg/ml, respectively. Hernandezine (25, 50 and 100 μg / ml) could not inhibit the formation of MDA in-duced by AA. Hernandezine could increase the concentration of cAMP in rabbit platelet and inhibit the increase of the...

Hernandezine, an isoquinoline alkaloid, is one of the active ingredients isolated from Thalictrum glandulosissimum. It was found to inhibit markedly rat platelet aggregation induced by collagen, ADP, calicimycin (A-23187) and arachidonic acid (AA) in vitro. The IC50 were 14.5, 41.6, 44.1 and 48.3μg/ml, respectively. Hernandezine (25, 50 and 100 μg / ml) could not inhibit the formation of MDA in-duced by AA. Hernandezine could increase the concentration of cAMP in rabbit platelet and inhibit the increase of the cytosolic free Ca2+ concentration in human platelet induced by thrombin.

海兰地嗪(Her)体外对胶原,ADP,A23187和AA诱导的大鼠血小板聚集有明显抑制作用,其IC_(50)分别为14.5,41.6,44.1和48.3μg/ml。Her对AA诱导的大鼠血小板MDA生成不能抑制,但能升高兔血小板cAMP水平和抑制凝血酶诱导的人血小板胞浆内游离钙离子浓度升高。Her的抗血小板聚集作用机理可能与升高血小板内cAMP水平和抑制细胞内游离钙离子浓度升高有关。

This paper reported the estimation of free calcium concentration in rabbit resting lymphocytes, and the effect of (-) Daurisoline (8701) on the cyto-plasmic free calcium concentration by using fluorescent indicator Fura -2/Am estimating technique. Results were compared with the effect of the Ca2-ionophore A23187.

采用钙荧光指示剂Fura—2/Am定量测试法检测了静息淋巴细胞胞浆内游离钙浓度,并以Ca~(2+)载体A23187作为阳性对照.观察了(一)蝙蝠葛苏林碱(8701)对兔淋巴细胞胞浆内Ca~(2+)浓度的影响。结果表明:8701的各种实验浓度均可显著地促进淋巴细胞内Ca~(2+)浓度增加,在浓度为10~(-4)mol·L~(-1)时,增加细胞内Ca~(2+)浓度的作用显著高于Ca~(2+)载体A23187的作用(P<0.01),提示该药有可能作为淋巴细胞的刺激剂或在高浓度时可能造成淋巴细胞的Ca~(2+)中毒作用。

Ca~(2+) are as Second messenger that regulate numerous physiological reaction. In this paper we propose a mathematical modelling method starting from the affection of transmembrane Ca~(2+) influence on aggregation of platelets By the method we apply the cytoplasmic Ca~(2+) concentration to express the character of p1atelet aggregation, that from one side affect the level of ageing and morbid star for platelets.

钙离子作为第二信使物质,调节着众多的生理反映。本文从钙离子的跨膜转运对血小板聚集的影响出发,提出一种数学模型方法,力图以胞浆内游离钙浓度作为指标去研究和标志血小板的聚集特性,它从一个侧面去反映血小板的老化程度或病态程度。

 
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